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The map label for this gene is appC [H]

Identifier: 85859106

GI number: 85859106

Start: 1283468

End: 1284304

Strand: Direct

Name: appC [H]

Synonym: SYN_01342

Alternate gene names: 85859106

Gene position: 1283468-1284304 (Clockwise)

Preceding gene: 85859105

Following gene: 85859108

Centisome position: 40.37

GC content: 61.89

Gene sequence:

>837_bases
ATGGATAAGGATTTTCGGCGTCGATTTATAAAAAACCGCCTTGCTCTGGCGGGGAGCGTCCTGGTGCTGATCCTCTTTGT
CGTTTCCCTGCTTGCGCCCTGGCTGGCCCCTTACGACCCCAACGCCATCGATCTGAATAACATCCTTGCGCCGCCGTCAG
CCGCGCACTGGTTCGGGACGGACCAACTGGGGCGGGATGTCTGCAGCCGGATGATCTGGGGGGCGGGGATTTCTCTCAAG
GTCGGCTTCGTGGCGACGGGCATCGCCATTGTCATCGGAACGATTCTGGGAGCGGTTGCGGGCTACTACGGCGGCTGGGT
GGATGCCCTGATCATGCGGTTCGTGGACATCATGCTCTGCTTCCCCACGTTTTTCCTGATCCTGGCCGTGATCGCCCTGC
TGGAGCCTTCCATCTGGAACATCATGATCATCATCGGGATTACGGGCTGGATGGGGATCACGCGGCTGGTGCGCGCCGAT
TTCATCTCGCTGAAACAGCGGGATTTTATCCTGGCGGCCCGGGCCATCGGGGCAAGCGACCTGCGGATCATCTTTATCCA
CATGCTGCCCAATGCCATGGCCTCCGTGCTGGTGGCGGCGACCCTGGGCGTCGCGGGGGCGATCCTGACCGAATCGGCGC
TGAGTTTTCTGGGCATCGGGGTTCAGCCACCCACACCAAGCTGGGGAAACATCCTCACCGCCGGCAAGGACAACATCGAC
ATCGCCTGGTGGCTGTCCCTCTATCCCGGACTGGCGATCCTTCTCACCGTGCTGGGCTACAACCTCCTTGGCGAGGGGAT
CCGCGACTCCCTCGATCCCCGTCTGCGCCGCCGCTGA

Upstream 100 bases:

>100_bases
ATCGGGGCCGTGCTGACGCTGATCGGCAACCTGCTGGCCGACGTTTCCTACGCGCTGGCCGATCCCAGGATCCGGGTGTC
CTGAAAGGACTGGAATAGTT

Downstream 100 bases:

>100_bases
AAAAATCTTACCGGGTGCTCCGGTTTAAGCAAGGAAGAGGGGGGGAGGCGACGAAGTCGTTTACAGAATACGTTGAGGCG
CCGCAGGCGAAGCCGAAGCC

Product: peptide ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 278

Protein sequence:

>278_residues
MDKDFRRRFIKNRLALAGSVLVLILFVVSLLAPWLAPYDPNAIDLNNILAPPSAAHWFGTDQLGRDVCSRMIWGAGISLK
VGFVATGIAIVIGTILGAVAGYYGGWVDALIMRFVDIMLCFPTFFLILAVIALLEPSIWNIMIIIGITGWMGITRLVRAD
FISLKQRDFILAARAIGASDLRIIFIHMLPNAMASVLVAATLGVAGAILTESALSFLGIGVQPPTPSWGNILTAGKDNID
IAWWLSLYPGLAILLTVLGYNLLGEGIRDSLDPRLRRR

Sequences:

>Translated_278_residues
MDKDFRRRFIKNRLALAGSVLVLILFVVSLLAPWLAPYDPNAIDLNNILAPPSAAHWFGTDQLGRDVCSRMIWGAGISLK
VGFVATGIAIVIGTILGAVAGYYGGWVDALIMRFVDIMLCFPTFFLILAVIALLEPSIWNIMIIIGITGWMGITRLVRAD
FISLKQRDFILAARAIGASDLRIIFIHMLPNAMASVLVAATLGVAGAILTESALSFLGIGVQPPTPSWGNILTAGKDNID
IAWWLSLYPGLAILLTVLGYNLLGEGIRDSLDPRLRRR
>Mature_278_residues
MDKDFRRRFIKNRLALAGSVLVLILFVVSLLAPWLAPYDPNAIDLNNILAPPSAAHWFGTDQLGRDVCSRMIWGAGISLK
VGFVATGIAIVIGTILGAVAGYYGGWVDALIMRFVDIMLCFPTFFLILAVIALLEPSIWNIMIIIGITGWMGITRLVRAD
FISLKQRDFILAARAIGASDLRIIFIHMLPNAMASVLVAATLGVAGAILTESALSFLGIGVQPPTPSWGNILTAGKDNID
IAWWLSLYPGLAILLTVLGYNLLGEGIRDSLDPRLRRR

Specific function: This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transportin

COG id: COG1173

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787054, Length=275, Percent_Identity=45.0909090909091, Blast_Score=248, Evalue=3e-67,
Organism=Escherichia coli, GI1787760, Length=261, Percent_Identity=42.5287356321839, Blast_Score=221, Evalue=4e-59,
Organism=Escherichia coli, GI1789964, Length=281, Percent_Identity=43.7722419928826, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1787498, Length=276, Percent_Identity=38.0434782608696, Blast_Score=179, Evalue=2e-46,
Organism=Escherichia coli, GI1789889, Length=244, Percent_Identity=38.1147540983607, Blast_Score=173, Evalue=1e-44,
Organism=Escherichia coli, GI1788505, Length=226, Percent_Identity=38.9380530973451, Blast_Score=162, Evalue=2e-41,
Organism=Escherichia coli, GI1787549, Length=275, Percent_Identity=33.4545454545455, Blast_Score=138, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 30213; Mature: 30213

Theoretical pI: Translated: 9.51; Mature: 9.51

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKDFRRRFIKNRLALAGSVLVLILFVVSLLAPWLAPYDPNAIDLNNILAPPSAAHWFGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCH
DQLGRDVCSRMIWGAGISLKVGFVATGIAIVIGTILGAVAGYYGGWVDALIMRFVDIMLC
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPTFFLILAVIALLEPSIWNIMIIIGITGWMGITRLVRADFISLKQRDFILAARAIGASD
HHHHHHHHHHHHHHCCCHHHEEHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LRIIFIHMLPNAMASVLVAATLGVAGAILTESALSFLGIGVQPPTPSWGNILTAGKDNID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCH
IAWWLSLYPGLAILLTVLGYNLLGEGIRDSLDPRLRRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC
>Mature Secondary Structure
MDKDFRRRFIKNRLALAGSVLVLILFVVSLLAPWLAPYDPNAIDLNNILAPPSAAHWFGT
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHCCCH
DQLGRDVCSRMIWGAGISLKVGFVATGIAIVIGTILGAVAGYYGGWVDALIMRFVDIMLC
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FPTFFLILAVIALLEPSIWNIMIIIGITGWMGITRLVRADFISLKQRDFILAARAIGASD
HHHHHHHHHHHHHHCCCHHHEEHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LRIIFIHMLPNAMASVLVAATLGVAGAILTESALSFLGIGVQPPTPSWGNILTAGKDNID
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCH
IAWWLSLYPGLAILLTVLGYNLLGEGIRDSLDPRLRRR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7997159; 9384377 [H]