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The map label for this gene is lpxH [H]

Identifier: 85858944

GI number: 85858944

Start: 1126053

End: 1126853

Strand: Direct

Name: lpxH [H]

Synonym: SYN_01366

Alternate gene names: 85858944

Gene position: 1126053-1126853 (Clockwise)

Preceding gene: 85858942

Following gene: 85858945

Centisome position: 35.42

GC content: 48.69

Gene sequence:

>801_bases
ATGAAAGCGGTATTTATCGCCGATGCGCATCTGAAGAACAGCTGTGATCTGAATTATCGGAAAATGCTGAATTTTCTTTC
GCTGCTCATTCATCCTTCCGATGTCAATTCGCCCTTGAAGAGGGAATCTGCGGCTCGCCGGCGGATTCCCGTGGATGATC
TTTATATCGGGGGAGATTTTTTCGATTTCTGGTTTTGCCGGGGCGAAATGGTTTATCCGGAATTTCTGCCGGTTATCCTG
GCATTGATCGCTGTCAGGGATAGGGGGGTCCGCGTTCATTTTGCGGAAGGCAATCATGATTTCTTCCTTTCCGATTACTT
CACCCGGATACTGGGGATGGAGGTTTTTACCGACTGGACGACGCTCATGCTGGATGACTGTAAAGTCCTTTTTTCCCACG
GCGATACGGTGGACAGGAGTAATGTTCAATATCTGAGGCTTCGAAAACTTTTGAGGAGCCGCTTGATCTATCAGCTCCAG
CGCCGCCTTCCTCTTTCCTGGTTGTGGAAGATTGCCGCTGCCTGTTCAGCCACGAGCAAGGGCCAATCCCGGCCTTCCGA
AGAAAAACTTTCCGGAATACTGCATGCTTTTTCTGCAGCGAAGATACAGGGAGAGATTGACGCTGTGATCCTGGGGCATT
GCCACCAACCGATTCTGAAAGAATTTCAAATCAGGGGGCGGAGAAAATATACCATCACTCTGGGGGACTGGATCCGGCAT
TTTTCCTATCTCTATTATGAAGATGGAATTTTCAGGTTTCATTGTTTCAAAGGTGAAAAAAGCGCGCGTTGCGGAACCTA
A

Upstream 100 bases:

>100_bases
ATCTTTTTCGGAAGAGTCCTTTATGCTAATGAAGAACGCCTTCTTGAGATAAACGATTGAACAGAAAGAAAAAACAGACG
GAAGGAACATCCTGGATTTC

Downstream 100 bases:

>100_bases
CTTTTCTTTTTTCGTAATGAATTTTCTTGTCACCTGAAGTGAACATAATGCTGGACTTATCTTGATTGATGTGTTAGCAC
GCCCACAAATTTGATCGGGA

Product: calcineurin-like phosphoesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MKAVFIADAHLKNSCDLNYRKMLNFLSLLIHPSDVNSPLKRESAARRRIPVDDLYIGGDFFDFWFCRGEMVYPEFLPVIL
ALIAVRDRGVRVHFAEGNHDFFLSDYFTRILGMEVFTDWTTLMLDDCKVLFSHGDTVDRSNVQYLRLRKLLRSRLIYQLQ
RRLPLSWLWKIAAACSATSKGQSRPSEEKLSGILHAFSAAKIQGEIDAVILGHCHQPILKEFQIRGRRKYTITLGDWIRH
FSYLYYEDGIFRFHCFKGEKSARCGT

Sequences:

>Translated_266_residues
MKAVFIADAHLKNSCDLNYRKMLNFLSLLIHPSDVNSPLKRESAARRRIPVDDLYIGGDFFDFWFCRGEMVYPEFLPVIL
ALIAVRDRGVRVHFAEGNHDFFLSDYFTRILGMEVFTDWTTLMLDDCKVLFSHGDTVDRSNVQYLRLRKLLRSRLIYQLQ
RRLPLSWLWKIAAACSATSKGQSRPSEEKLSGILHAFSAAKIQGEIDAVILGHCHQPILKEFQIRGRRKYTITLGDWIRH
FSYLYYEDGIFRFHCFKGEKSARCGT
>Mature_266_residues
MKAVFIADAHLKNSCDLNYRKMLNFLSLLIHPSDVNSPLKRESAARRRIPVDDLYIGGDFFDFWFCRGEMVYPEFLPVIL
ALIAVRDRGVRVHFAEGNHDFFLSDYFTRILGMEVFTDWTTLMLDDCKVLFSHGDTVDRSNVQYLRLRKLLRSRLIYQLQ
RRLPLSWLWKIAAACSATSKGQSRPSEEKLSGILHAFSAAKIQGEIDAVILGHCHQPILKEFQIRGRRKYTITLGDWIRH
FSYLYYEDGIFRFHCFKGEKSARCGT

Specific function: Catalyzes the hydrolysis of the pyrophosphate bond of UDP-2,3-diacylglucosamine to yield 2,3-diacylglucosamine 1- phosphate (lipid X) and UMP [H]

COG id: COG2908

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lpxH family [H]

Homologues:

Organism=Escherichia coli, GI1786735, Length=238, Percent_Identity=29.8319327731092, Blast_Score=78, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010138 [H]

Pfam domain/function: NA

EC number: 3.6.1.-

Molecular weight: Translated: 30952; Mature: 30952

Theoretical pI: Translated: 9.35; Mature: 9.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVFIADAHLKNSCDLNYRKMLNFLSLLIHPSDVNSPLKRESAARRRIPVDDLYIGGDF
CCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEECCCH
FDFWFCRGEMVYPEFLPVILALIAVRDRGVRVHFAEGNHDFFLSDYFTRILGMEVFTDWT
HHHHHCCCCEECHHHHHHHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHH
TLMLDDCKVLFSHGDTVDRSNVQYLRLRKLLRSRLIYQLQRRLPLSWLWKIAAACSATSK
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
GQSRPSEEKLSGILHAFSAAKIQGEIDAVILGHCHQPILKEFQIRGRRKYTITLGDWIRH
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCEEEEEEHHHHHHH
FSYLYYEDGIFRFHCFKGEKSARCGT
HHHHEEECCEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MKAVFIADAHLKNSCDLNYRKMLNFLSLLIHPSDVNSPLKRESAARRRIPVDDLYIGGDF
CCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCEEECCCH
FDFWFCRGEMVYPEFLPVILALIAVRDRGVRVHFAEGNHDFFLSDYFTRILGMEVFTDWT
HHHHHCCCCEECHHHHHHHHHHHHHHCCCEEEEEECCCCCEEHHHHHHHHHHHHHHHHHH
TLMLDDCKVLFSHGDTVDRSNVQYLRLRKLLRSRLIYQLQRRLPLSWLWKIAAACSATSK
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCC
GQSRPSEEKLSGILHAFSAAKIQGEIDAVILGHCHQPILKEFQIRGRRKYTITLGDWIRH
CCCCCCHHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHCCCEEEEEEHHHHHHH
FSYLYYEDGIFRFHCFKGEKSARCGT
HHHHEEECCEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA