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The map label for this gene is tnaA

Identifier: 85858803

GI number: 85858803

Start: 992650

End: 994095

Strand: Direct

Name: tnaA

Synonym: SYN_01455

Alternate gene names: 85858803

Gene position: 992650-994095 (Clockwise)

Preceding gene: 85858802

Following gene: 85858809

Centisome position: 31.22

GC content: 52.97

Gene sequence:

>1446_bases
ATGAACATCAGACTGTCCAACGGGAAGCTGCTCCCTGTGGAAATGCACAAGATCAAGATCGTCCAGCAAACGAGACTGCC
CTCGGCCGATGAGCGCCTGAGGGCTATGGAGGAGGCCGGCTACAATACCTTCCTGCTTCGAACCCGCGATGTCTTTCTGG
ATATGTTGACGGATAGCGGCACCAATGCCATGAGCGATAATCAGTTGGGCGCCATGATGGTGGCCGATGATGCCTACGCC
GGCAGTGAAAGCTTCTACAAGTTGCAGGATGCCGTCAATGAGGTCTTCGGCCTTCCTTATTTGCTTCCGGCGCATCAAGG
CCGTGCAGCGGAACACCTGTTGGCCAAGGTTTTAGTCAAACCTGGCGATGTTGTTCCCATGAACTATCATTTTACGACTA
CCAAGGCCCACTTCACACTGGCCGGAGGGACGGTGCTGGAAATCTTTACGGATGAAGCCTTGAATACGGACAGCAAAGAG
TTCTTCAAAGGCAATATTGATACAGATAAATTTCTCGATGTGATCAAAACCTACGGATCAGAACGTATCTCCTTTGTTCG
GATGGAGGCCACGACCAATCTTCTGGGTGGCCAGCCTTTTTCCATGGCCAATTACAAGAAAGTGAAGGAAATCGCCGCGG
CGAACAACATCAAACTCGTTCTCGACGCCAGTCTGATTTCCGAACAGGCCTATTTCATCAAGCAGCGGGAAGACGGCTAT
AAGGATCGATCCATCGCTGAGATTATCTGGGAACTTGCAGACATCGCGGATATCGTTTACCTGTCGGGACGGAAGAGCTG
TGCTGTCCGTGGCGGGTTTATCGCCACGAAGCGTAAGGATATTTTTGATACCATTCTTCCCTGGCTTCCCGTTTATGAAG
GATTTGCAACCTACGGCGGCATGTCCACAAAAGAGATCGAGGCCATGGCTGTAGGCATCCGGGAAATGACTCAATACAGT
GTGGCGAGCAGTTCGGCGGATATGATCCAGTATTTTGCTGAACAATTAAAGACACGGGGCATTCCCGTGGTGACGCCTCC
GGGGGGGCTGGCCTGTCACATTGATGCCCGCCGCTTTCTTCCGGACATCCCTCCCTCCAAGTATATTGCCGCCTCCCTGA
CTTCGGCCGTCTACCTCATATCCGGGGCAAGGGGGATGGAACGGGGCACCATGTCCGAGCAACGTGACCCGGATGGCAAT
GAGGTCTTTTCAGATCTGGAACTCCTGAGGCTTGCTGTGCCGCGCCGAACCTACACCCTTGCGCAAATCGATTACGTCGT
TGATCGGGTGGCCTGGCTCGCAAATCACCGGGATCTGATCAAGGGGTTGATCTTTTATGAAGAACCGCCTATCCTGCGCT
TCTTCTTCGGCAAGATGAGGGCCATTGACAACTGGGGCGCCAAGCTCGTGGAAGCCTTCAAAAATGATTTTGGGCCGGAG
CTGTAA

Upstream 100 bases:

>100_bases
GGGATTTTCTCTATGGCTTTTTTGGAATTTTTCATGATCCTGCTTCAGCCCTGCGGCGGCAATAGAAATTCAATAGCTAA
CCCTTATTAAGGAGGATTTT

Downstream 100 bases:

>100_bases
GATATCAGACGATACCAAGAATTCAGTGCGTTCAGGAAATGGATTTCTGAACGCACTGAATTCTTTAAAAAACCATTTTC
AAATTTAAAAAGGTTCCATG

Product: tryptophanase

Products: NA

Alternate protein names: Beta-tyrosinase [H]

Number of amino acids: Translated: 481; Mature: 481

Protein sequence:

>481_residues
MNIRLSNGKLLPVEMHKIKIVQQTRLPSADERLRAMEEAGYNTFLLRTRDVFLDMLTDSGTNAMSDNQLGAMMVADDAYA
GSESFYKLQDAVNEVFGLPYLLPAHQGRAAEHLLAKVLVKPGDVVPMNYHFTTTKAHFTLAGGTVLEIFTDEALNTDSKE
FFKGNIDTDKFLDVIKTYGSERISFVRMEATTNLLGGQPFSMANYKKVKEIAAANNIKLVLDASLISEQAYFIKQREDGY
KDRSIAEIIWELADIADIVYLSGRKSCAVRGGFIATKRKDIFDTILPWLPVYEGFATYGGMSTKEIEAMAVGIREMTQYS
VASSSADMIQYFAEQLKTRGIPVVTPPGGLACHIDARRFLPDIPPSKYIAASLTSAVYLISGARGMERGTMSEQRDPDGN
EVFSDLELLRLAVPRRTYTLAQIDYVVDRVAWLANHRDLIKGLIFYEEPPILRFFFGKMRAIDNWGAKLVEAFKNDFGPE
L

Sequences:

>Translated_481_residues
MNIRLSNGKLLPVEMHKIKIVQQTRLPSADERLRAMEEAGYNTFLLRTRDVFLDMLTDSGTNAMSDNQLGAMMVADDAYA
GSESFYKLQDAVNEVFGLPYLLPAHQGRAAEHLLAKVLVKPGDVVPMNYHFTTTKAHFTLAGGTVLEIFTDEALNTDSKE
FFKGNIDTDKFLDVIKTYGSERISFVRMEATTNLLGGQPFSMANYKKVKEIAAANNIKLVLDASLISEQAYFIKQREDGY
KDRSIAEIIWELADIADIVYLSGRKSCAVRGGFIATKRKDIFDTILPWLPVYEGFATYGGMSTKEIEAMAVGIREMTQYS
VASSSADMIQYFAEQLKTRGIPVVTPPGGLACHIDARRFLPDIPPSKYIAASLTSAVYLISGARGMERGTMSEQRDPDGN
EVFSDLELLRLAVPRRTYTLAQIDYVVDRVAWLANHRDLIKGLIFYEEPPILRFFFGKMRAIDNWGAKLVEAFKNDFGPE
L
>Mature_481_residues
MNIRLSNGKLLPVEMHKIKIVQQTRLPSADERLRAMEEAGYNTFLLRTRDVFLDMLTDSGTNAMSDNQLGAMMVADDAYA
GSESFYKLQDAVNEVFGLPYLLPAHQGRAAEHLLAKVLVKPGDVVPMNYHFTTTKAHFTLAGGTVLEIFTDEALNTDSKE
FFKGNIDTDKFLDVIKTYGSERISFVRMEATTNLLGGQPFSMANYKKVKEIAAANNIKLVLDASLISEQAYFIKQREDGY
KDRSIAEIIWELADIADIVYLSGRKSCAVRGGFIATKRKDIFDTILPWLPVYEGFATYGGMSTKEIEAMAVGIREMTQYS
VASSSADMIQYFAEQLKTRGIPVVTPPGGLACHIDARRFLPDIPPSKYIAASLTSAVYLISGARGMERGTMSEQRDPDGN
EVFSDLELLRLAVPRRTYTLAQIDYVVDRVAWLANHRDLIKGLIFYEEPPILRFFFGKMRAIDNWGAKLVEAFKNDFGPE
L

Specific function: Tryptophan catabolism. [C]

COG id: COG3033

COG function: function code E; Tryptophanase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-eliminating lyase family [H]

Homologues:

Organism=Escherichia coli, GI87082323, Length=473, Percent_Identity=35.5179704016913, Blast_Score=289, Evalue=3e-79,

Paralogues:

None

Copy number: 7160 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 460 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001597
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011166
- InterPro:   IPR018176
- InterPro:   IPR013441 [H]

Pfam domain/function: PF01212 Beta_elim_lyase [H]

EC number: =4.1.99.2 [H]

Molecular weight: Translated: 53796; Mature: 53796

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRLSNGKLLPVEMHKIKIVQQTRLPSADERLRAMEEAGYNTFLLRTRDVFLDMLTDSG
CEEEECCCCEEEEEHHHEEEEHHHCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCC
TNAMSDNQLGAMMVADDAYAGSESFYKLQDAVNEVFGLPYLLPAHQGRAAEHLLAKVLVK
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCC
PGDVVPMNYHFTTTKAHFTLAGGTVLEIFTDEALNTDSKEFFKGNIDTDKFLDVIKTYGS
CCCEEEEEEEEEECEEEEEEECCEEEEEEECHHCCCCCHHHHCCCCCHHHHHHHHHHCCC
ERISFVRMEATTNLLGGQPFSMANYKKVKEIAAANNIKLVLDASLISEQAYFIKQREDGY
CCEEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
KDRSIAEIIWELADIADIVYLSGRKSCAVRGGFIATKRKDIFDTILPWLPVYEGFATYGG
CCHHHHHHHHHHHHHHHHEEECCCCCEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHCC
MSTKEIEAMAVGIREMTQYSVASSSADMIQYFAEQLKTRGIPVVTPPGGLACHIDARRFL
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEHHHCC
PDIPPSKYIAASLTSAVYLISGARGMERGTMSEQRDPDGNEVFSDLELLRLAVPRRTYTL
CCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
AQIDYVVDRVAWLANHRDLIKGLIFYEEPPILRFFFGKMRAIDNWGAKLVEAFKNDFGPE
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
L
C
>Mature Secondary Structure
MNIRLSNGKLLPVEMHKIKIVQQTRLPSADERLRAMEEAGYNTFLLRTRDVFLDMLTDSG
CEEEECCCCEEEEEHHHEEEEHHHCCCCHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCC
TNAMSDNQLGAMMVADDAYAGSESFYKLQDAVNEVFGLPYLLPAHQGRAAEHLLAKVLVK
CCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCHHHHHHHHHHHCC
PGDVVPMNYHFTTTKAHFTLAGGTVLEIFTDEALNTDSKEFFKGNIDTDKFLDVIKTYGS
CCCEEEEEEEEEECEEEEEEECCEEEEEEECHHCCCCCHHHHCCCCCHHHHHHHHHHCCC
ERISFVRMEATTNLLGGQPFSMANYKKVKEIAAANNIKLVLDASLISEQAYFIKQREDGY
CCEEEEEEEHHHHHCCCCCCCHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCC
KDRSIAEIIWELADIADIVYLSGRKSCAVRGGFIATKRKDIFDTILPWLPVYEGFATYGG
CCHHHHHHHHHHHHHHHHEEECCCCCEEEECCEEECCHHHHHHHHHHHHHHHHHHHHHCC
MSTKEIEAMAVGIREMTQYSVASSSADMIQYFAEQLKTRGIPVVTPPGGLACHIDARRFL
CCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEHHHCC
PDIPPSKYIAASLTSAVYLISGARGMERGTMSEQRDPDGNEVFSDLELLRLAVPRRTYTL
CCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHH
AQIDYVVDRVAWLANHRDLIKGLIFYEEPPILRFFFGKMRAIDNWGAKLVEAFKNDFGPE
HHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA