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The map label for this gene is ilvK [H]

Identifier: 85858681

GI number: 85858681

Start: 858721

End: 859098

Strand: Direct

Name: ilvK [H]

Synonym: SYN_03155

Alternate gene names: 85858681

Gene position: 858721-859098 (Clockwise)

Preceding gene: 85858680

Following gene: 85858682

Centisome position: 27.01

GC content: 50.26

Gene sequence:

>378_bases
GTGGGAACCAGCAATATCTTTTTCCTGATTGGCGATGAACTGGTGACGGCCCCTCTGGAAGGGACCATCCTGCCCGGAGT
GACTCGGGATTCCGTGATTAAAATGGCCCGGCACTGGGGGATGACCGTTTCGGAACGGAGACTTTCCATGGAGGAAGTTC
TTCAGGCAGTCGAAACGGGAACGCTTAAGGAAGTTTTCGCGTCCGGCACGGCGGCTGTGGTTTCTCCTGTCGGTCAGTTT
TATTATCAGGGTAAAGAGTATCAGGTTAATGGCGGAAAGACGGGGCCTTTAACGGAAAAACTTTACAATGAAATCCTTGG
TATTCAGTATGGCGAAAAAGAGGATCCATTCGGCTGGAGAATGAAAATTTCCGACTGA

Upstream 100 bases:

>100_bases
AATTATGCGGCAAGTCTTTATGCCAGTCAGATTGCCATGAAAATGGGCTACACCCAGGGTTTTATGGCTGGATGCCATCG
AGAGAAAGTACGTCGAAGAG

Downstream 100 bases:

>100_bases
GGATTCCCGATGAAATCTCATCCACAAGCCTGTGGACAAGCCTGTGGATAACGCTGTTGATAAATCGGGTAAGTCTGTAA
TTGTTACGAATATTGACCGA

Product: branched-chain amino acid aminotransferase

Products: NA

Alternate protein names: BCAT 2; Vegetative protein 85; VEG85 [H]

Number of amino acids: Translated: 125; Mature: 124

Protein sequence:

>125_residues
MGTSNIFFLIGDELVTAPLEGTILPGVTRDSVIKMARHWGMTVSERRLSMEEVLQAVETGTLKEVFASGTAAVVSPVGQF
YYQGKEYQVNGGKTGPLTEKLYNEILGIQYGEKEDPFGWRMKISD

Sequences:

>Translated_125_residues
MGTSNIFFLIGDELVTAPLEGTILPGVTRDSVIKMARHWGMTVSERRLSMEEVLQAVETGTLKEVFASGTAAVVSPVGQF
YYQGKEYQVNGGKTGPLTEKLYNEILGIQYGEKEDPFGWRMKISD
>Mature_124_residues
GTSNIFFLIGDELVTAPLEGTILPGVTRDSVIKMARHWGMTVSERRLSMEEVLQAVETGTLKEVFASGTAAVVSPVGQFY
YQGKEYQVNGGKTGPLTEKLYNEILGIQYGEKEDPFGWRMKISD

Specific function: Transaminates branched-chain amino acids and ketoglutarate [H]

COG id: COG0115

COG function: function code EH; Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI296010902, Length=131, Percent_Identity=38.9312977099237, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI38176287, Length=131, Percent_Identity=38.9312977099237, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI296010904, Length=121, Percent_Identity=40.495867768595, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI296010906, Length=131, Percent_Identity=38.9312977099237, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI296010900, Length=131, Percent_Identity=38.9312977099237, Blast_Score=91, Evalue=2e-19,
Organism=Homo sapiens, GI50658084, Length=118, Percent_Identity=42.3728813559322, Blast_Score=88, Evalue=2e-18,
Organism=Homo sapiens, GI258614015, Length=118, Percent_Identity=42.3728813559322, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI48994963, Length=115, Percent_Identity=38.2608695652174, Blast_Score=75, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17568601, Length=126, Percent_Identity=48.4126984126984, Blast_Score=91, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17565728, Length=95, Percent_Identity=38.9473684210526, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322608, Length=140, Percent_Identity=42.1428571428571, Blast_Score=96, Evalue=2e-21,
Organism=Saccharomyces cerevisiae, GI6322002, Length=127, Percent_Identity=41.7322834645669, Blast_Score=82, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641779, Length=125, Percent_Identity=42.4, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: 2342 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 11,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001544
- InterPro:   IPR018300
- InterPro:   IPR005786 [H]

Pfam domain/function: PF01063 Aminotran_4 [H]

EC number: =2.6.1.42 [H]

Molecular weight: Translated: 13809; Mature: 13678

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTSNIFFLIGDELVTAPLEGTILPGVTRDSVIKMARHWGMTVSERRLSMEEVLQAVETG
CCCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCC
TLKEVFASGTAAVVSPVGQFYYQGKEYQVNGGKTGPLTEKLYNEILGIQYGEKEDPFGWR
HHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
MKISD
EEECC
>Mature Secondary Structure 
GTSNIFFLIGDELVTAPLEGTILPGVTRDSVIKMARHWGMTVSERRLSMEEVLQAVETG
CCCCEEEEECCCEEECCCCCCCCCCCCHHHHHHHHHHHCCCHHHHHCCHHHHHHHHCCC
TLKEVFASGTAAVVSPVGQFYYQGKEYQVNGGKTGPLTEKLYNEILGIQYGEKEDPFGWR
HHHHHHHCCCHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCEE
MKISD
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 7934828; 9298659 [H]