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The map label for this gene is ruvA

Identifier: 85858586

GI number: 85858586

Start: 747690

End: 748304

Strand: Direct

Name: ruvA

Synonym: SYN_02972

Alternate gene names: 85858586

Gene position: 747690-748304 (Clockwise)

Preceding gene: 85858585

Following gene: 85858587

Centisome position: 23.52

GC content: 41.95

Gene sequence:

>615_bases
ATGATTGCGCAGATTCGAGGAAAACTGATACTTAAAACCGTATCGATGGTTATCATTGATAATCACGGGATCGGCTATGA
GGTAATGATTCCGCTATCCACGTATTATGAACTACCCGACGTGGGAAGCGAAGTCAGTTTGTTCGTTTATACCTTTTTTA
AACAGGATTCAATACTTCTCGTAGGTTTTTGCACAGAAAACGAAAAACAGCTTTTCAAGTTGATGATTTCGGTTTCCGGT
ATCGGTCCGCGCCTTGCGGTAAATGTGTTGTCCGGGATCAACTCGAGTGAACTTATTCATGCCATAGCAAATAATGATTT
GAATCGTCTTCTGAAAGTTCCGGGTCTTGGAAGAAAAATGGCACAAAGAGTCATTTTGGAACTTCGGGACAAGGTATCTG
GATGGACATCCAAAGAGCAGATAACCTTCATAAATAATAAAAAGGATGCAATCGATCAGAGCGTTATGGAAGAGGATGCC
ATCTCCGCGTTGATAAATCTGGGGTATAAGAGCCAGGCAGCAAAGGATGCAATTGATCGAGTCATTTCAGAGGGTGGTGA
AAATAAATCATTGGATGTGATCCTGAAGAAAGCGCTGAAAGTACTGGCCATGTAG

Upstream 100 bases:

>100_bases
CATTATGAAATTGTCAGAGCTTCCTCCCGCAGATGCTTCAGACGCAATCGCAGTAGCCATATGTCATCTCAACCATCAGA
AGAAAAATCACATATAATCC

Downstream 100 bases:

>100_bases
CCAAACGGAAATAAGATTCATAAACCGGATGAATCGTTTGGCGAACCGATATAAAGTGTGTCCCTCATTGCATGAGTTAA
TCCAAAAAATATCAGTAGTG

Product: holliday junction DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MIAQIRGKLILKTVSMVIIDNHGIGYEVMIPLSTYYELPDVGSEVSLFVYTFFKQDSILLVGFCTENEKQLFKLMISVSG
IGPRLAVNVLSGINSSELIHAIANNDLNRLLKVPGLGRKMAQRVILELRDKVSGWTSKEQITFINNKKDAIDQSVMEEDA
ISALINLGYKSQAAKDAIDRVISEGGENKSLDVILKKALKVLAM

Sequences:

>Translated_204_residues
MIAQIRGKLILKTVSMVIIDNHGIGYEVMIPLSTYYELPDVGSEVSLFVYTFFKQDSILLVGFCTENEKQLFKLMISVSG
IGPRLAVNVLSGINSSELIHAIANNDLNRLLKVPGLGRKMAQRVILELRDKVSGWTSKEQITFINNKKDAIDQSVMEEDA
ISALINLGYKSQAAKDAIDRVISEGGENKSLDVILKKALKVLAM
>Mature_204_residues
MIAQIRGKLILKTVSMVIIDNHGIGYEVMIPLSTYYELPDVGSEVSLFVYTFFKQDSILLVGFCTENEKQLFKLMISVSG
IGPRLAVNVLSGINSSELIHAIANNDLNRLLKVPGLGRKMAQRVILELRDKVSGWTSKEQITFINNKKDAIDQSVMEEDA
ISALINLGYKSQAAKDAIDRVISEGGENKSLDVILKKALKVLAM

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=205, Percent_Identity=33.1707317073171, Blast_Score=148, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_SYNAS (Q2LRA9)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_460788.1
- ProteinModelPortal:   Q2LRA9
- SMR:   Q2LRA9
- STRING:   Q2LRA9
- GeneID:   3885054
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_02972
- NMPDR:   fig|56780.10.peg.729
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   Q2LRA9
- BioCyc:   SACI56780:SYN_02972-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 22528; Mature: 22528

Theoretical pI: Translated: 8.42; Mature: 8.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIAQIRGKLILKTVSMVIIDNHGIGYEVMIPLSTYYELPDVGSEVSLFVYTFFKQDSILL
CCCHHHHHHHHHHHEEEEECCCCCCEEEEEEHHHHCCCCCCCCCCEEEEEEEECCCCEEE
VGFCTENEKQLFKLMISVSGIGPRLAVNVLSGINSSELIHAIANNDLNRLLKVPGLGRKM
EEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCCHHH
AQRVILELRDKVSGWTSKEQITFINNKKDAIDQSVMEEDAISALINLGYKSQAAKDAIDR
HHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VISEGGENKSLDVILKKALKVLAM
HHHCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIAQIRGKLILKTVSMVIIDNHGIGYEVMIPLSTYYELPDVGSEVSLFVYTFFKQDSILL
CCCHHHHHHHHHHHEEEEECCCCCCEEEEEEHHHHCCCCCCCCCCEEEEEEEECCCCEEE
VGFCTENEKQLFKLMISVSGIGPRLAVNVLSGINSSELIHAIANNDLNRLLKVPGLGRKM
EEEECCCHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHCCCHHHHHCCCCCCHHH
AQRVILELRDKVSGWTSKEQITFINNKKDAIDQSVMEEDAISALINLGYKSQAAKDAIDR
HHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
VISEGGENKSLDVILKKALKVLAM
HHHCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA