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The map label for this gene is ftsA [H]

Identifier: 85858530

GI number: 85858530

Start: 683937

End: 685166

Strand: Direct

Name: ftsA [H]

Synonym: SYN_03127

Alternate gene names: 85858530

Gene position: 683937-685166 (Clockwise)

Preceding gene: 85858529

Following gene: 85858531

Centisome position: 21.51

GC content: 54.07

Gene sequence:

>1230_bases
ATGGGTATGCAGGGCAATGTCATCGTCGGATTGGATATAGGCACGACAAAAACCTGTGCCATTGTTGGTGAAGTAACCGA
TACAGGCATTGATATCATCGGCATCGGTTCTCATCCCTCGGACGGATTGAGGAAAGGCGTCGTAGTGAACATCGACAGCA
CCGTAGAGGCGATCAAAGCAGCAGTGGAAGAGGCGGAACGTATGTCCGGCTGTGAAATCGGTTCTGTCTTTACGGGGATT
GCCGGCGGCCATATTAAAGCGCAGAACAGCCTGGGCATCGTGGCCGTGAAGGGGCGTGAAGTAGGCAGCGAGGATGTGGA
ACGTGCTATCGAAGCCGCCAAAGCGATCGCCATTCCCCTGGACCGGCAGATCCTGCATACACTGCCCCAGAGTTATGTTG
TGGACGAACAGGATGGGATTAAGGATCCGGTAGGCATGTCTGGTGTCAGGCTGGAAGCGAAGGTCCATGTCGTAACCGGT
GTGGTGACCTCCATCCAGAATATTGAAAAATCCGTTACCCGTGTTGGGCTGGACATCAATGATATTGTTCTGGAACAGCT
TGCAGCCAGTCAGGCCGTGCTGAGCGATGATGAACGCGATCTGGGAGTGGCTCTGCTGGACATCGGGGGCGGAACCACGA
ATATTGCGGTTTTCTGGGAGGGAAGCATCCGTCATACGGCTGTTATTCCCGTCGGTGGTAATTACGTGACCAGTGATATC
GCCACCGGCTTGAGAACGCCCCTTAACGAGGCGGAAAAAATCAAAATCGGCTTTGGGTGCGCCTATGCGCCGATGATTCC
CAAGGAGGAAACCATTGAGGTGCCAAGCGTAGGCGGCCGGGAGCCTCGTGTCGTGTCGCGCCAGATCCTGGGGCGGATCA
TTGAGGCGCGTATGGAAGAAATTCTGAACATGGCATATAAGGAAATCGTTCGCTCCGGCTATGAAGACGTTCTGGCTGCG
GGAGTTGTGCTTGCAGGTGGGACGGCTCTCCTGGACGGCATTACGGAACTGACGGAGCAGATTTTCAATATGCCGGTCCG
GAGGGGGTATCCCTCAGGTATCGGAGGATTGACAGATGTGGTTAACAGCCCCATGTATGCGACAGGCGTCGGTCTTGTCC
TTTACGGGAGTAAAAACCTGGCCAAGGTTGTCGTGAGGAAGGGCGAGAAGGGAAAGGCGGGGGATGATGTGATCGCGAAA
TTCAAAAAATGGATATTAGAATTCTTCTAG

Upstream 100 bases:

>100_bases
CGGTGGCTATGCCGACAACTTCGTTCATTTCAAGACAGGAGAGGATGCACAAGTTCTTGTTTCACATCCTCCCATTATCA
GAGAAAGGTGGACAGAGCAA

Downstream 100 bases:

>100_bases
GGGGGTGTCATGTTTGAATTGTCTGAGTCGGAAAATTTCAGTTCCGCAAAAATCAAGGTTATTGGAATCGGTGGTGGTGG
AGGGAACGCAATTAACACTA

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MGMQGNVIVGLDIGTTKTCAIVGEVTDTGIDIIGIGSHPSDGLRKGVVVNIDSTVEAIKAAVEEAERMSGCEIGSVFTGI
AGGHIKAQNSLGIVAVKGREVGSEDVERAIEAAKAIAIPLDRQILHTLPQSYVVDEQDGIKDPVGMSGVRLEAKVHVVTG
VVTSIQNIEKSVTRVGLDINDIVLEQLAASQAVLSDDERDLGVALLDIGGGTTNIAVFWEGSIRHTAVIPVGGNYVTSDI
ATGLRTPLNEAEKIKIGFGCAYAPMIPKEETIEVPSVGGREPRVVSRQILGRIIEARMEEILNMAYKEIVRSGYEDVLAA
GVVLAGGTALLDGITELTEQIFNMPVRRGYPSGIGGLTDVVNSPMYATGVGLVLYGSKNLAKVVVRKGEKGKAGDDVIAK
FKKWILEFF

Sequences:

>Translated_409_residues
MGMQGNVIVGLDIGTTKTCAIVGEVTDTGIDIIGIGSHPSDGLRKGVVVNIDSTVEAIKAAVEEAERMSGCEIGSVFTGI
AGGHIKAQNSLGIVAVKGREVGSEDVERAIEAAKAIAIPLDRQILHTLPQSYVVDEQDGIKDPVGMSGVRLEAKVHVVTG
VVTSIQNIEKSVTRVGLDINDIVLEQLAASQAVLSDDERDLGVALLDIGGGTTNIAVFWEGSIRHTAVIPVGGNYVTSDI
ATGLRTPLNEAEKIKIGFGCAYAPMIPKEETIEVPSVGGREPRVVSRQILGRIIEARMEEILNMAYKEIVRSGYEDVLAA
GVVLAGGTALLDGITELTEQIFNMPVRRGYPSGIGGLTDVVNSPMYATGVGLVLYGSKNLAKVVVRKGEKGKAGDDVIAK
FKKWILEFF
>Mature_408_residues
GMQGNVIVGLDIGTTKTCAIVGEVTDTGIDIIGIGSHPSDGLRKGVVVNIDSTVEAIKAAVEEAERMSGCEIGSVFTGIA
GGHIKAQNSLGIVAVKGREVGSEDVERAIEAAKAIAIPLDRQILHTLPQSYVVDEQDGIKDPVGMSGVRLEAKVHVVTGV
VTSIQNIEKSVTRVGLDINDIVLEQLAASQAVLSDDERDLGVALLDIGGGTTNIAVFWEGSIRHTAVIPVGGNYVTSDIA
TGLRTPLNEAEKIKIGFGCAYAPMIPKEETIEVPSVGGREPRVVSRQILGRIIEARMEEILNMAYKEIVRSGYEDVLAAG
VVLAGGTALLDGITELTEQIFNMPVRRGYPSGIGGLTDVVNSPMYATGVGLVLYGSKNLAKVVVRKGEKGKAGDDVIAKF
KKWILEFF

Specific function: This protein may be involved in anomalous filament growth. May be a component of the septum [H]

COG id: COG0849

COG function: function code D; Actin-like ATPase involved in cell division

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI1786282, Length=382, Percent_Identity=45.5497382198953, Blast_Score=349, Evalue=2e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020823
- InterPro:   IPR003494 [H]

Pfam domain/function: PF02491 FtsA [H]

EC number: NA

Molecular weight: Translated: 43155; Mature: 43024

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMQGNVIVGLDIGTTKTCAIVGEVTDTGIDIIGIGSHPSDGLRKGVVVNIDSTVEAIKA
CCCCCCEEEEEECCCCCEEEEEECCCCCCEEEEECCCCCCCHHHCCEEEEECHHHHHHHH
AVEEAERMSGCEIGSVFTGIAGGHIKAQNSLGIVAVKGREVGSEDVERAIEAAKAIAIPL
HHHHHHHHCCCCHHHHHHCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC
DRQILHTLPQSYVVDEQDGIKDPVGMSGVRLEAKVHVVTGVVTSIQNIEKSVTRVGLDIN
CHHHHHHCCHHEECCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCHH
DIVLEQLAASQAVLSDDERDLGVALLDIGGGTTNIAVFWEGSIRHTAVIPVGGNYVTSDI
HHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEECCCCEEEEEECCCCEEHHHH
ATGLRTPLNEAEKIKIGFGCAYAPMIPKEETIEVPSVGGREPRVVSRQILGRIIEARMEE
HHHHCCCCCCCCEEEEEECEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ILNMAYKEIVRSGYEDVLAAGVVLAGGTALLDGITELTEQIFNMPVRRGYPSGIGGLTDV
HHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHH
VNSPMYATGVGLVLYGSKNLAKVVVRKGEKGKAGDDVIAKFKKWILEFF
HCCCCEECCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GMQGNVIVGLDIGTTKTCAIVGEVTDTGIDIIGIGSHPSDGLRKGVVVNIDSTVEAIKA
CCCCCEEEEEECCCCCEEEEEECCCCCCEEEEECCCCCCCHHHCCEEEEECHHHHHHHH
AVEEAERMSGCEIGSVFTGIAGGHIKAQNSLGIVAVKGREVGSEDVERAIEAAKAIAIPL
HHHHHHHHCCCCHHHHHHCCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCC
DRQILHTLPQSYVVDEQDGIKDPVGMSGVRLEAKVHVVTGVVTSIQNIEKSVTRVGLDIN
CHHHHHHCCHHEECCCCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCHH
DIVLEQLAASQAVLSDDERDLGVALLDIGGGTTNIAVFWEGSIRHTAVIPVGGNYVTSDI
HHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEEEECCCCEEEEEECCCCEEHHHH
ATGLRTPLNEAEKIKIGFGCAYAPMIPKEETIEVPSVGGREPRVVSRQILGRIIEARMEE
HHHHCCCCCCCCEEEEEECEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ILNMAYKEIVRSGYEDVLAAGVVLAGGTALLDGITELTEQIFNMPVRRGYPSGIGGLTDV
HHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCCCCCCHHHHH
VNSPMYATGVGLVLYGSKNLAKVVVRKGEKGKAGDDVIAKFKKWILEFF
HCCCCEECCCEEEEECCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043; 8581173 [H]