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The map label for this gene is murG

Identifier: 85858526

GI number: 85858526

Start: 679387

End: 680472

Strand: Direct

Name: murG

Synonym: SYN_01746

Alternate gene names: 85858526

Gene position: 679387-680472 (Clockwise)

Preceding gene: 85858525

Following gene: 85858527

Centisome position: 21.37

GC content: 52.85

Gene sequence:

>1086_bases
ATGACTGTTCGAGTGATCATTGCCGGTGGAGGGACCGGCGGGCATCTGTTTCCCGGTGTGGCAATTGCCGAGGAGTTGCT
ACGACGAGACAGGGAGAACAGAGTTCTTTTTGTCGGAACGAAGCGGGGGATTGAAAAAAAAGTGCTGAAGGACCTTGGTT
TCCGCCTGAAACTGCTGAATGTGGAAGGCATCAAAGGGCGTGGAGTGATGCGGTCCAGTCTGGCCCTTTTAAAACTTCCG
GGAAGCCTGATGCAGTCGATGAAAATAATTCGTGATTTCCGACCGGATGTCGTTATCGGCGTCGGAGGCTATGCTTCGGG
TCCAGCCGTCATGGCAGCCCATCTGATGGGAATCAAGACCGCTATTGCTGAACAGAATTCCATCCCGGGACTTACCAATC
GCATTCTGGGCCGGTTTGTTGATCGTGTTTTCCTCAGCTTTTCCGACGGGGGGAAATGGTTCTCCGCTAAAAAAGCTGCA
GTTTCAGGAAATCCGATCCGGGCCGCCTTCTTCAATGGGAAACCGGTTCTTGAAAAGACCGGGGATCAATTTTCCCTGCT
GGTTTTCGGAGGAAGTCAGGGAGCTCATGCAATCAATTCGGCGTTTCAGGATGCCCTTCCTTTTCTGCAGCTTTTGAAGG
GGTGTCTCCGTATTGTTCATCAAACCGGGGAACGGGATTGTGAAAGCATGGCTGCCGCGTATAGCGCACAGGGGTTTTCC
GCCCGTGTTGTTCCCTTCATTCGAGATATGGCAGCGGCATACGAGGCTGCCGATCTCCTCATCTGCCGGGCGGGAGCCAC
CTCAATTGCCGAGATCACCGCCATCGGCAAGGCGGCGATCCTCATCCCCTTTCCCTATGCGATTGGGGATCACCAGACGG
AAAACGCCAAAGTTCTCCTCAAGGCCGGGGCGGCCGTAATGATCCCGGAAAAGGATCTTACCGGGAAAAAACTCGCGGAT
GAGATTCAGAATTTTTATTCTCATCCCTCCCTGCTTAAGGATATGGAAGCAAAAGCAGCCAGTCTGGGAAACATTTATGC
AGCTTCGGATATTGTCGATTCCTGTATGGCCATGATCAGGCTGTAG

Upstream 100 bases:

>100_bases
CCTTTCTCAGTTACGGCGGGACGTCGCTGCTGATGAGCCTGACGGCTGTGGGCATCCTTCTGAACATCTCCACTTATACG
GAAATAAAGGAAGAGTCCTG

Downstream 100 bases:

>100_bases
AAAACTATTTTGTATAGACATGATACAATATATAGTGTATGTATCTGCAATTTATACCACATAAAGTGTGATATGTTTCA
CACATGAGGGGAATGCCATT

Product: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 361; Mature: 360

Protein sequence:

>361_residues
MTVRVIIAGGGTGGHLFPGVAIAEELLRRDRENRVLFVGTKRGIEKKVLKDLGFRLKLLNVEGIKGRGVMRSSLALLKLP
GSLMQSMKIIRDFRPDVVIGVGGYASGPAVMAAHLMGIKTAIAEQNSIPGLTNRILGRFVDRVFLSFSDGGKWFSAKKAA
VSGNPIRAAFFNGKPVLEKTGDQFSLLVFGGSQGAHAINSAFQDALPFLQLLKGCLRIVHQTGERDCESMAAAYSAQGFS
ARVVPFIRDMAAAYEAADLLICRAGATSIAEITAIGKAAILIPFPYAIGDHQTENAKVLLKAGAAVMIPEKDLTGKKLAD
EIQNFYSHPSLLKDMEAKAASLGNIYAASDIVDSCMAMIRL

Sequences:

>Translated_361_residues
MTVRVIIAGGGTGGHLFPGVAIAEELLRRDRENRVLFVGTKRGIEKKVLKDLGFRLKLLNVEGIKGRGVMRSSLALLKLP
GSLMQSMKIIRDFRPDVVIGVGGYASGPAVMAAHLMGIKTAIAEQNSIPGLTNRILGRFVDRVFLSFSDGGKWFSAKKAA
VSGNPIRAAFFNGKPVLEKTGDQFSLLVFGGSQGAHAINSAFQDALPFLQLLKGCLRIVHQTGERDCESMAAAYSAQGFS
ARVVPFIRDMAAAYEAADLLICRAGATSIAEITAIGKAAILIPFPYAIGDHQTENAKVLLKAGAAVMIPEKDLTGKKLAD
EIQNFYSHPSLLKDMEAKAASLGNIYAASDIVDSCMAMIRL
>Mature_360_residues
TVRVIIAGGGTGGHLFPGVAIAEELLRRDRENRVLFVGTKRGIEKKVLKDLGFRLKLLNVEGIKGRGVMRSSLALLKLPG
SLMQSMKIIRDFRPDVVIGVGGYASGPAVMAAHLMGIKTAIAEQNSIPGLTNRILGRFVDRVFLSFSDGGKWFSAKKAAV
SGNPIRAAFFNGKPVLEKTGDQFSLLVFGGSQGAHAINSAFQDALPFLQLLKGCLRIVHQTGERDCESMAAAYSAQGFSA
RVVPFIRDMAAAYEAADLLICRAGATSIAEITAIGKAAILIPFPYAIGDHQTENAKVLLKAGAAVMIPEKDLTGKKLADE
IQNFYSHPSLLKDMEAKAASLGNIYAASDIVDSCMAMIRL

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=343, Percent_Identity=33.8192419825073, Blast_Score=181, Evalue=5e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_SYNAS (Q2LR48)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_460728.1
- ProteinModelPortal:   Q2LR48
- STRING:   Q2LR48
- GeneID:   3885153
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_01746
- NMPDR:   fig|56780.10.peg.673
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   IGFGGYP
- PhylomeDB:   Q2LR48
- BioCyc:   SACI56780:SYN_01746-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38564; Mature: 38432

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVRVIIAGGGTGGHLFPGVAIAEELLRRDRENRVLFVGTKRGIEKKVLKDLGFRLKLLN
CEEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCEEEEEE
VEGIKGRGVMRSSLALLKLPGSLMQSMKIIRDFRPDVVIGVGGYASGPAVMAAHLMGIKT
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHH
AIAEQNSIPGLTNRILGRFVDRVFLSFSDGGKWFSAKKAAVSGNPIRAAFFNGKPVLEKT
HHHCCCCCCCHHHHHHHHHHHHHHHEECCCCCEEECCHHCCCCCCEEEEEECCCCCCCCC
GDQFSLLVFGGSQGAHAINSAFQDALPFLQLLKGCLRIVHQTGERDCESMAAAYSAQGFS
CCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
ARVVPFIRDMAAAYEAADLLICRAGATSIAEITAIGKAAILIPFPYAIGDHQTENAKVLL
CHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEEE
KAGAAVMIPEKDLTGKKLADEIQNFYSHPSLLKDMEAKAASLGNIYAASDIVDSCMAMIR
ECCCEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
L
C
>Mature Secondary Structure 
TVRVIIAGGGTGGHLFPGVAIAEELLRRDRENRVLFVGTKRGIEKKVLKDLGFRLKLLN
EEEEEEEECCCCCCCCCCHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHCCCEEEEEE
VEGIKGRGVMRSSLALLKLPGSLMQSMKIIRDFRPDVVIGVGGYASGPAVMAAHLMGIKT
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHH
AIAEQNSIPGLTNRILGRFVDRVFLSFSDGGKWFSAKKAAVSGNPIRAAFFNGKPVLEKT
HHHCCCCCCCHHHHHHHHHHHHHHHEECCCCCEEECCHHCCCCCCEEEEEECCCCCCCCC
GDQFSLLVFGGSQGAHAINSAFQDALPFLQLLKGCLRIVHQTGERDCESMAAAYSAQGFS
CCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
ARVVPFIRDMAAAYEAADLLICRAGATSIAEITAIGKAAILIPFPYAIGDHQTENAKVLL
CHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCEEEEEECCCCCCCCCCCCCEEEE
KAGAAVMIPEKDLTGKKLADEIQNFYSHPSLLKDMEAKAASLGNIYAASDIVDSCMAMIR
ECCCEEEECCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHC
L
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA