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The map label for this gene is rsmH

Identifier: 85858517

GI number: 85858517

Start: 669242

End: 670189

Strand: Direct

Name: rsmH

Synonym: SYN_01737

Alternate gene names: 85858517

Gene position: 669242-670189 (Clockwise)

Preceding gene: 85858516

Following gene: 85858518

Centisome position: 21.05

GC content: 54.11

Gene sequence:

>948_bases
ATGCCGGAAGGGAAGTATTCCTATCATGAGCCCGTGTTGCTTGAAGAGGCCATTGCCTCCCTTAACTGCCGCGGTGGCGG
GATTTACGTTGACGGAACGGTGGGTGGCGGAGGACATGCCGCCTTGATTCTGGAGAGATCGGCACCGGATGGCTTCCTTC
TGGGAATGGATGTCGATGGCGACGCCCTGCAGGCTGCAGAGAAGCGCCTGATGCCTTTTGGCCGACGGAAAACGCTTGTC
AAGGCAAATTATGCCGACATGCGAAAAGTGCTTGCAGACCTGAAAATCCTGCAGGTTGACGGTATTCTGCTTGACCTTGG
AGTCTCTTCCCACCAGTTGGATGCGGCGGAACGAGGGTTCAGCCTGCTGAAGGATGCCCCGCTGGATATGCGCATGGATT
CCGAAGCCGGCCGAAGCGCGTATGATGTTGTCAATACCTGTTCTGAGCGAGAATTGAAGGATATCATCCGAAAATACGGA
GAAGAAATCATGGCAGGTCGAATCGCCCGGGCGATTGCCGAGAAGCGGAAAGATACTCCGATCAAGTCAACGACTCAACT
GGCAGCCATTGTGGCGGGCGCATTGCCCGGGGGCTTTCGGCACAAAAAAATTCATCCCGCAACCCGGACCTTCCAGGCTC
TCAGAATTTACATTAATAACGAACTTTCGAATCTACATCGAGCCATTTTCGACAGTACCGACTGTCTCAAACCGGGTGGA
CGGTTTTCCATCATTTCTTTTCACTCGCTGGAAGACAGCTTGGTAAAGAATGGCTTTCGTTCCCTGGAAAAAGGGTGCAT
CTGTCCGGCTGATATGCCGGTTTGTGCCTGCGGACAAAGTCCCCGGTTAAAGGTCATCACCCGGAAACCGATATCTCCCT
GCCGGGATGAGGTTGAAGCTAATCCCCGGTCGCGGAGCGCGCGGCTTCGAACTGCGGAAAGGATTTAG

Upstream 100 bases:

>100_bases
TTGAAATATGGGACAGGGATCTCTATGAAGCGGATCGTCTGAATACCTCAGGAAGTCTCAGTAATTTCGGGGATTACATG
ACGGAGCTCGGTCTCTGAAA

Downstream 100 bases:

>100_bases
AGCTTGCCGGTTGACGAAATCCCAGCCAGGACATCCCAGATTGAACATCAGGAACAGAAAAAGTCGACGGGGTTGAGATA
TTCATCCCTGATGATCGGCG

Product: S-adenosyl-methyltransferase mraW

Products: NA

Alternate protein names: 16S rRNA m(4)C1402 methyltransferase; rRNA (cytosine-N(4)-)-methyltransferase RsmH

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MPEGKYSYHEPVLLEEAIASLNCRGGGIYVDGTVGGGGHAALILERSAPDGFLLGMDVDGDALQAAEKRLMPFGRRKTLV
KANYADMRKVLADLKILQVDGILLDLGVSSHQLDAAERGFSLLKDAPLDMRMDSEAGRSAYDVVNTCSERELKDIIRKYG
EEIMAGRIARAIAEKRKDTPIKSTTQLAAIVAGALPGGFRHKKIHPATRTFQALRIYINNELSNLHRAIFDSTDCLKPGG
RFSIISFHSLEDSLVKNGFRSLEKGCICPADMPVCACGQSPRLKVITRKPISPCRDEVEANPRSRSARLRTAERI

Sequences:

>Translated_315_residues
MPEGKYSYHEPVLLEEAIASLNCRGGGIYVDGTVGGGGHAALILERSAPDGFLLGMDVDGDALQAAEKRLMPFGRRKTLV
KANYADMRKVLADLKILQVDGILLDLGVSSHQLDAAERGFSLLKDAPLDMRMDSEAGRSAYDVVNTCSERELKDIIRKYG
EEIMAGRIARAIAEKRKDTPIKSTTQLAAIVAGALPGGFRHKKIHPATRTFQALRIYINNELSNLHRAIFDSTDCLKPGG
RFSIISFHSLEDSLVKNGFRSLEKGCICPADMPVCACGQSPRLKVITRKPISPCRDEVEANPRSRSARLRTAERI
>Mature_314_residues
PEGKYSYHEPVLLEEAIASLNCRGGGIYVDGTVGGGGHAALILERSAPDGFLLGMDVDGDALQAAEKRLMPFGRRKTLVK
ANYADMRKVLADLKILQVDGILLDLGVSSHQLDAAERGFSLLKDAPLDMRMDSEAGRSAYDVVNTCSERELKDIIRKYGE
EIMAGRIARAIAEKRKDTPIKSTTQLAAIVAGALPGGFRHKKIHPATRTFQALRIYINNELSNLHRAIFDSTDCLKPGGR
FSIISFHSLEDSLVKNGFRSLEKGCICPADMPVCACGQSPRLKVITRKPISPCRDEVEANPRSRSARLRTAERI

Specific function: Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA

COG id: COG0275

COG function: function code M; Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmH family

Homologues:

Organism=Homo sapiens, GI165377209, Length=339, Percent_Identity=39.5280235988201, Blast_Score=202, Evalue=4e-52,
Organism=Homo sapiens, GI165377202, Length=191, Percent_Identity=43.455497382199, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI1786270, Length=311, Percent_Identity=44.3729903536978, Blast_Score=248, Evalue=3e-67,
Organism=Drosophila melanogaster, GI62472493, Length=327, Percent_Identity=37.6146788990826, Blast_Score=177, Evalue=9e-45,
Organism=Drosophila melanogaster, GI28571637, Length=327, Percent_Identity=37.6146788990826, Blast_Score=177, Evalue=9e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RSMH_SYNAS (Q2LR39)

Other databases:

- EMBL:   CP000252
- RefSeq:   YP_460719.1
- ProteinModelPortal:   Q2LR39
- SMR:   Q2LR39
- STRING:   Q2LR39
- GeneID:   3882657
- GenomeReviews:   CP000252_GR
- KEGG:   sat:SYN_01737
- NMPDR:   fig|56780.10.peg.665
- eggNOG:   COG0275
- HOGENOM:   HBG302779
- OMA:   PQLDDPE
- PhylomeDB:   Q2LR39
- BioCyc:   SACI56780:SYN_01737-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01007
- InterPro:   IPR002903
- PANTHER:   PTHR11265
- PIRSF:   PIRSF004486
- TIGRFAMs:   TIGR00006

Pfam domain/function: PF01795 Methyltransf_5

EC number: NA

Molecular weight: Translated: 34490; Mature: 34359

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: BINDING 57-57 BINDING 91-91 BINDING 105-105 BINDING 112-112

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPEGKYSYHEPVLLEEAIASLNCRGGGIYVDGTVGGGGHAALILERSAPDGFLLGMDVDG
CCCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEECCCCCCEEEEECCCC
DALQAAEKRLMPFGRRKTLVKANYADMRKVLADLKILQVDGILLDLGVSSHQLDAAERGF
HHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHEEEECCEEEECCCCCHHHHHHHHHH
SLLKDAPLDMRMDSEAGRSAYDVVNTCSERELKDIIRKYGEEIMAGRIARAIAEKRKDTP
HHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IKSTTQLAAIVAGALPGGFRHKKIHPATRTFQALRIYINNELSNLHRAIFDSTDCLKPGG
CCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RFSIISFHSLEDSLVKNGFRSLEKGCICPADMPVCACGQSPRLKVITRKPISPCRDEVEA
CEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEECCCCCHHHHHHCC
NPRSRSARLRTAERI
CCCCHHHHHHHHCCC
>Mature Secondary Structure 
PEGKYSYHEPVLLEEAIASLNCRGGGIYVDGTVGGGGHAALILERSAPDGFLLGMDVDG
CCCCCCCCCCHHHHHHHHHCCCCCCCEEEECCCCCCCEEEEEEECCCCCCEEEEECCCC
DALQAAEKRLMPFGRRKTLVKANYADMRKVLADLKILQVDGILLDLGVSSHQLDAAERGF
HHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHEEEECCEEEECCCCCHHHHHHHHHH
SLLKDAPLDMRMDSEAGRSAYDVVNTCSERELKDIIRKYGEEIMAGRIARAIAEKRKDTP
HHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
IKSTTQLAAIVAGALPGGFRHKKIHPATRTFQALRIYINNELSNLHRAIFDSTDCLKPGG
CCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
RFSIISFHSLEDSLVKNGFRSLEKGCICPADMPVCACGQSPRLKVITRKPISPCRDEVEA
CEEEEEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCEEEEECCCCCHHHHHHCC
NPRSRSARLRTAERI
CCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA