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The map label for this gene is mreB [H]

Identifier: 85858467

GI number: 85858467

Start: 623116

End: 624153

Strand: Direct

Name: mreB [H]

Synonym: SYN_00554

Alternate gene names: 85858467

Gene position: 623116-624153 (Clockwise)

Preceding gene: 85858461

Following gene: 85858468

Centisome position: 19.6

GC content: 53.37

Gene sequence:

>1038_bases
TTGCTGTTCGATTTCATTTTAGGGAAGTTTTCAAATGATCTGGCCATAGATCTGGGAACAGCCAATACTCTTGTCTATGT
CAAGAACAAGGGGATTGTTCTGAGTGAACCTTCCGTTGTAGCGGTTCATAAGGATTCCCGAGGCGTTAAAAAGGTGTTGG
CTGTGGGCGCCGAGGCGAAAAAGATGCTTGGAAGAACACCGGGCAATATTGTCGCGATAAGGCCCATGAGAGATGGTGTT
ATCGCTGACTTCGATATTACGGAAGCCATGCTGCGGCATTTCATTCTCAGTGTGCACAATCGCCGGGCCCTGGTCAGACC
CAGAATCATCGTGTCCATTCCCTCCGGGATCACGCAGGTGGAGAGACGAGCCGTGCGGGAAACCGTGGAGTCGGCAGGCG
CCCGTGAAATCTATCTGATCGAGGAGCCCATGGCGGCCGCCATAGGTGCGGGACTGCCCGTATCGGAGCCGATCAGTTCC
ATGATTGTTGACATCGGTGGAGGGACAACGGAAGTTGCGGTCATTTCACTGGCCGGCATCGTGTATTCCCAGTCTGTCAG
GGTGGCGGGAGACAAGATTGACGCGGAGATCGTCAATTTTATAAAGAGAAAGTACAGTCTTCTCATCGGCGAACGTACGG
GAGAGATCATCAAGACGACCATAGGCTGCGCCTATCCGGAAGACGAAATCCGCACTGTCGATGTCAAGGGAAGGGATCTG
ATTTCCGGCATTCCCAAGACGGTGGAAATTAATTCCGAGGAAATCCGGGATGCTATTATGGAACCCATCAAGATCATCGT
GGATACAATCAAGGATGCTCTGGAAAATGCTCCGCCGGAACTGGCGGGAGATATTGTGGACCGGGGAATCGTATTGACGG
GAGGCGGCGCCCTTCTGCGGAAGCTTGATGTCCTGATTCGGGAAGAGACGGGCCTGCCAATCACCATTGCCGACGATCCA
CTGACGACGGTAGCCATCGGTGCGGGGATGGCACTCGATCAACTGGACGTATTGAAGGAAGTCGCGATTCAGGCCTGA

Upstream 100 bases:

>100_bases
TTGATTAGGGTCATTAAATAGGATATAGGGAACAACCTGCGACTAGGGGCGCAAGTTCCGGCAGTCAGGTATTTCATAAC
AAAATCAAGGGGGAAGGACA

Downstream 100 bases:

>100_bases
GTCTGAGATGGGCTTCAATCTGAATATCACTGCTTAAATGGGATGTTCTGCTTTCGCTGCGGCCGGGTAGATCCGGATTT
CATAATTCGTGTCACGGCAG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MLFDFILGKFSNDLAIDLGTANTLVYVKNKGIVLSEPSVVAVHKDSRGVKKVLAVGAEAKKMLGRTPGNIVAIRPMRDGV
IADFDITEAMLRHFILSVHNRRALVRPRIIVSIPSGITQVERRAVRETVESAGAREIYLIEEPMAAAIGAGLPVSEPISS
MIVDIGGGTTEVAVISLAGIVYSQSVRVAGDKIDAEIVNFIKRKYSLLIGERTGEIIKTTIGCAYPEDEIRTVDVKGRDL
ISGIPKTVEINSEEIRDAIMEPIKIIVDTIKDALENAPPELAGDIVDRGIVLTGGGALLRKLDVLIREETGLPITIADDP
LTTVAIGAGMALDQLDVLKEVAIQA

Sequences:

>Translated_345_residues
MLFDFILGKFSNDLAIDLGTANTLVYVKNKGIVLSEPSVVAVHKDSRGVKKVLAVGAEAKKMLGRTPGNIVAIRPMRDGV
IADFDITEAMLRHFILSVHNRRALVRPRIIVSIPSGITQVERRAVRETVESAGAREIYLIEEPMAAAIGAGLPVSEPISS
MIVDIGGGTTEVAVISLAGIVYSQSVRVAGDKIDAEIVNFIKRKYSLLIGERTGEIIKTTIGCAYPEDEIRTVDVKGRDL
ISGIPKTVEINSEEIRDAIMEPIKIIVDTIKDALENAPPELAGDIVDRGIVLTGGGALLRKLDVLIREETGLPITIADDP
LTTVAIGAGMALDQLDVLKEVAIQA
>Mature_345_residues
MLFDFILGKFSNDLAIDLGTANTLVYVKNKGIVLSEPSVVAVHKDSRGVKKVLAVGAEAKKMLGRTPGNIVAIRPMRDGV
IADFDITEAMLRHFILSVHNRRALVRPRIIVSIPSGITQVERRAVRETVESAGAREIYLIEEPMAAAIGAGLPVSEPISS
MIVDIGGGTTEVAVISLAGIVYSQSVRVAGDKIDAEIVNFIKRKYSLLIGERTGEIIKTTIGCAYPEDEIRTVDVKGRDL
ISGIPKTVEINSEEIRDAIMEPIKIIVDTIKDALENAPPELAGDIVDRGIVLTGGGALLRKLDVLIREETGLPITIADDP
LTTVAIGAGMALDQLDVLKEVAIQA

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=340, Percent_Identity=62.3529411764706, Blast_Score=421, Evalue=1e-119,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 36971; Mature: 36971

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLFDFILGKFSNDLAIDLGTANTLVYVKNKGIVLSEPSVVAVHKDSRGVKKVLAVGAEAK
CCHHHHHHHCCCCEEEEECCCCEEEEEECCCEEEECCCEEEEECCCCHHHHHHHHCHHHH
KMLGRTPGNIVAIRPMRDGVIADFDITEAMLRHFILSVHNRRALVRPRIIVSIPSGITQV
HHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCHHHH
ERRAVRETVESAGAREIYLIEEPMAAAIGAGLPVSEPISSMIVDIGGGTTEVAVISLAGI
HHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCCCCCCHHHHEEECCCCCHHHHHHHHHHH
VYSQSVRVAGDKIDAEIVNFIKRKYSLLIGERTGEIIKTTIGCAYPEDEIRTVDVKGRDL
HHHCCEEECCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHCCCCCCCCCEEEECCCCHH
ISGIPKTVEINSEEIRDAIMEPIKIIVDTIKDALENAPPELAGDIVDRGIVLTGGGALLR
HHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHHHH
KLDVLIREETGLPITIADDPLTTVAIGAGMALDQLDVLKEVAIQA
HHHHHHEECCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLFDFILGKFSNDLAIDLGTANTLVYVKNKGIVLSEPSVVAVHKDSRGVKKVLAVGAEAK
CCHHHHHHHCCCCEEEEECCCCEEEEEECCCEEEECCCEEEEECCCCHHHHHHHHCHHHH
KMLGRTPGNIVAIRPMRDGVIADFDITEAMLRHFILSVHNRRALVRPRIIVSIPSGITQV
HHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCEEECCEEEEECCCCHHHH
ERRAVRETVESAGAREIYLIEEPMAAAIGAGLPVSEPISSMIVDIGGGTTEVAVISLAGI
HHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCCCCCCHHHHEEECCCCCHHHHHHHHHHH
VYSQSVRVAGDKIDAEIVNFIKRKYSLLIGERTGEIIKTTIGCAYPEDEIRTVDVKGRDL
HHHCCEEECCCCHHHHHHHHHHHHHHHEECCCCCHHHHHHHCCCCCCCCCEEEECCCCHH
ISGIPKTVEINSEEIRDAIMEPIKIIVDTIKDALENAPPELAGDIVDRGIVLTGGGALLR
HHCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHHHH
KLDVLIREETGLPITIADDPLTTVAIGAGMALDQLDVLKEVAIQA
HHHHHHEECCCCEEEECCCCCEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]