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The map label for this gene is nusG [H]

Identifier: 85858133

GI number: 85858133

Start: 299664

End: 300194

Strand: Direct

Name: nusG [H]

Synonym: SYN_00070

Alternate gene names: 85858133

Gene position: 299664-300194 (Clockwise)

Preceding gene: 85858132

Following gene: 85858134

Centisome position: 9.43

GC content: 47.46

Gene sequence:

>531_bases
ATGGCTTTCAAGTGGTATGTGGTACATACGTATTCCGGATTCGAAAGCAAGGTGAAGCAGTCTCTTCAGGAGAGGATCGA
AGCGGCAGGTATGCAGGCTCGTTTTTCCGATATCCTGATTCCTGAGGAAGATGTTGTTGAGCTTGTGTCCGGTGAGAAAA
AAACTTCAAAGCGCAAGTTCTTTCCTGGCTATATTCTTGTGAAGATGGAACTGGACGACGATACATGGCATCTTGTGAAG
GATACCCCGAAGGTGACAGGGTTTATCGGGAGCAGGGAAAAACCGTCGCCCATCCCGGATAAAGATGTGGAGCTTCTCAA
GACAAGAATCGATGAAGGCACCTTGAAACCCAAACCTAAGTTCAAATTTGAGGTGGGCGATCATGTAACCATTATCGACG
GTCCGTTTACGAATTTCGATGGGGTCATCGATGAGGTCAAGGCCGAGAAAGGAAAATTGAGGGTTATCGTCAGCATTTTC
GGTCGACCGACCCCGGTTGAGTTGGATTTCATTCAGGTTGTTCAGAGCTGA

Upstream 100 bases:

>100_bases
CTCTGTGGTCATTGTCGTTGTCATCATTGTTTCCACTTTCCTCGGCATTGTAGATTTCGGTCTTGCCAAGACAATTAAGC
TGGTTTTGGGTTAGTAAACT

Downstream 100 bases:

>100_bases
TCAGGAATAAGTTTTTCCGGGGGCTCACGATAATAAAGTAGCGTAGGGTGGTAATTATGGCCAAAAAAGTCATAGCAAAT
ATCAAGCTTCAAATTAAAGC

Product: transcription antitermination protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 176; Mature: 175

Protein sequence:

>176_residues
MAFKWYVVHTYSGFESKVKQSLQERIEAAGMQARFSDILIPEEDVVELVSGEKKTSKRKFFPGYILVKMELDDDTWHLVK
DTPKVTGFIGSREKPSPIPDKDVELLKTRIDEGTLKPKPKFKFEVGDHVTIIDGPFTNFDGVIDEVKAEKGKLRVIVSIF
GRPTPVELDFIQVVQS

Sequences:

>Translated_176_residues
MAFKWYVVHTYSGFESKVKQSLQERIEAAGMQARFSDILIPEEDVVELVSGEKKTSKRKFFPGYILVKMELDDDTWHLVK
DTPKVTGFIGSREKPSPIPDKDVELLKTRIDEGTLKPKPKFKFEVGDHVTIIDGPFTNFDGVIDEVKAEKGKLRVIVSIF
GRPTPVELDFIQVVQS
>Mature_175_residues
AFKWYVVHTYSGFESKVKQSLQERIEAAGMQARFSDILIPEEDVVELVSGEKKTSKRKFFPGYILVKMELDDDTWHLVKD
TPKVTGFIGSREKPSPIPDKDVELLKTRIDEGTLKPKPKFKFEVGDHVTIIDGPFTNFDGVIDEVKAEKGKLRVIVSIFG
RPTPVELDFIQVVQS

Specific function: Influences transcription termination and antitermination. Acts as a component of the transcription complex, and interacts with the termination factor rho and RNA polymerase [H]

COG id: COG0250

COG function: function code K; Transcription antiterminator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KOW domain [H]

Homologues:

Organism=Escherichia coli, GI1790414, Length=171, Percent_Identity=50.2923976608187, Blast_Score=188, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005824
- InterPro:   IPR001062
- InterPro:   IPR015869
- InterPro:   IPR006645
- InterPro:   IPR014722
- InterPro:   IPR008991 [H]

Pfam domain/function: PF00467 KOW; PF02357 NusG [H]

EC number: NA

Molecular weight: Translated: 20000; Mature: 19869

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS01014 NUSG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFKWYVVHTYSGFESKVKQSLQERIEAAGMQARFSDILIPEEDVVELVSGEKKTSKRKF
CCEEEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCCCCCCCEE
FPGYILVKMELDDDTWHLVKDTPKVTGFIGSREKPSPIPDKDVELLKTRIDEGTLKPKPK
CCCEEEEEEEECCCCEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
FKFEVGDHVTIIDGPFTNFDGVIDEVKAEKGKLRVIVSIFGRPTPVELDFIQVVQS
EEEECCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHCC
>Mature Secondary Structure 
AFKWYVVHTYSGFESKVKQSLQERIEAAGMQARFSDILIPEEDVVELVSGEKKTSKRKF
CEEEEEEEEECCHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHHCCCCCCCCCEE
FPGYILVKMELDDDTWHLVKDTPKVTGFIGSREKPSPIPDKDVELLKTRIDEGTLKPKPK
CCCEEEEEEEECCCCEEEEECCCCEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCC
FKFEVGDHVTIIDGPFTNFDGVIDEVKAEKGKLRVIVSIFGRPTPVELDFIQVVQS
EEEECCCEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]