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The map label for this gene is yyaL [H]

Identifier: 85858097

GI number: 85858097

Start: 267678

End: 269753

Strand: Direct

Name: yyaL [H]

Synonym: SYN_01448

Alternate gene names: 85858097

Gene position: 267678-269753 (Clockwise)

Preceding gene: 85858096

Following gene: 85858099

Centisome position: 8.42

GC content: 59.3

Gene sequence:

>2076_bases
ATGACCGATTCGACCCGCTCCACGGGTTCCTTCCGGAACCGCCTGCAGCAGGAAAAAAGTCCCTATCTGCTCCAGCATGC
CTCCAACCCGGTGGACTGGTATCCCTGGGGGGAGGAAGCCTTCGAAAAGGCCCGGCGGGAGGATAAGCCGATCTTTCTTT
CCATCGGTTATTCCACCTGTCACTGGTGCCACGTGATGGCCCATGAGTCTTTCGAGAACGAAGAGGTTGCCAGGCTGCTC
AATGAGTCTTTCATCTCCATCAAGGTGGACCGTGAGGAACGCCCCGATATCGACAAACTGTACATGGCTGTCTGTCAGCT
CCTGACCGGTGGAGGCGGCTGGCCGCTGACCATTCTCATGACCCCCGATCGGCGCCCTTTCTACGCGGGGACTTATATTC
CCAGGGAAAGCCGGTCGGGCATGGTGGGGATGCTGGTCCTGATTCCCGGACTCAGCGAGGTGTGGCGCAAGGAGCGGAAC
AGGATTCTGGAAACCGCCGGCGAGATTACGACGGCCCTGCAGGGGATGGATCAGGGCGGCCCCGGAGAACTGCCGCTGGA
CCGGGTTCTGCATGAAGCTTATGACGATCTGCGCCGCCGTTTCGATGCCCGTTATGGCGGGTTTGATTCCGCACCGAAAT
TTCCCATGGCTCAGCATTCCTTTTTTCTTCTGCGCTACGGCCGGAGGCAGGAAAACTCCCAGGCTCTGGCCATCGTGGAA
AAAACCCTGCAGTCGATGCGACGTGGGGGGATTTATGATGCGGTCGGCTTCGGTTTCCATCGGTACAGCACCGATGCCCA
ATGGCGGCTGCCGCACTTTGAAAAAATGCTTTACGATCAAGCCCTGCTGGCCATGGCCTATACCGAAGCCTTTCAGGCTG
CGGGACAGTCGTTGTACAAAAAAACGGCACGGGAGATTTTAACTTACGTCCTGCGGGATATGACCGCTCCGGAAGGCGGC
TTTTACTCGGCGGAGGACGCGGATACCGCCGGGGAGGAAGGGGCATTTTATCTCTGGACCGCTGAGGAACTTCGGCAGGT
GCTGCCGACGGAAGAGGCCGAACTGATGATCCGGGTCTACGCGATTCCTGAGGGCGGCAAACCTTCCGTACTGCACTGTT
CGTCATCGTATCCTGAACTGTCGGTTGATCTGGATCTTCCGGAAGAGAGGCTTCTGGAACGGCTGGAATCGGCGCGGCAG
AAACTTTTTCTTCAACGCGCAAAGCGGATTCGGCCTCTCCGGGATGACAAGATTCTGACCGACTGGAATGGACTGATGAT
TGCGGCCATGGCCCGGGCGGCAGCGGTCTTTGAAGAACCCGTGTACCTGCAGGCGGCCCGGGAGGCAGTCCGTTTCATTC
TGGAGAACCTGCGTGATCCGCGGGGGCGCCTCCTGCACCGCTGGCGGGAAGGTGAGGCGGCCATGCCGGCCGTTCTGGAC
GATTATGCCTTCCTGATCTGGGGGCTGATCGAGGCCTATGAAGCGACCTTCGATGCGAATCTTCTGCAGACGGCCCTTTC
TCTTGATGAAGAACTGACCGCCCATTTCTGGGACAACGCCTCTGGAGGCTATTTTTACACCCCGGATGATGGCGAGTCTT
TGCTGGTTCGCCAGAAGGAAAGCTATGACGGCGCCATTCCGTCGGGGAATTCCGTGGCCATGCTCAATCTGCTGCGTCTG
TCCCGCCTGACGGGTCAAGCGGGACTTGAAGAACGGGCCGTTGCGACGGCGCAGGCCTTTGCCGATTCCATCCGTTCCCT
GTCTGCCGCCCACACCTCGTTTATGGTCGCGCTGGATTATCTCGCCGGTCCTTCGGCTGAGGTGGTCATCGCCGGAAGCC
CGGAGGGAACGGACACCCGCGATATGCTGCGGGAACTGCGTCGGGCTTTCCTGCCTCACGTCACCGTTCTCCTGATTCCG
GACGAGGGGGAAAAGGGAATGCTCGCCGGAGTGGCGGAATTTACCGGGGGGATGACCCGTATCGATGGCCGGGCAACGGC
CTACGTCTGCCGGAATTTTTCCTGTCGAAAACCCACAACGGATCCGGCGGAAATGACCACCTTGCTTCGGGAATAG

Upstream 100 bases:

>100_bases
CATGCCGTTCACCTGCGGAAAAATAACCGTAAAACCGAAGCTTATGTGTTGAAAACAGCGGATTATCCTCTACTCCGCTG
TTTCAATAAGGAGAAAGATT

Downstream 100 bases:

>100_bases
CAGGAAAGGGAATTCCCTACCTGGGTTACGGATTTTCCGGGGTTTCCGGGGTTGCCGGAGTCGGCGGAGCGGACGCGGGC
GATGGCGTCATCGGCGGTAC

Product: thymidylate kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 690

Protein sequence:

>691_residues
MTDSTRSTGSFRNRLQQEKSPYLLQHASNPVDWYPWGEEAFEKARREDKPIFLSIGYSTCHWCHVMAHESFENEEVARLL
NESFISIKVDREERPDIDKLYMAVCQLLTGGGGWPLTILMTPDRRPFYAGTYIPRESRSGMVGMLVLIPGLSEVWRKERN
RILETAGEITTALQGMDQGGPGELPLDRVLHEAYDDLRRRFDARYGGFDSAPKFPMAQHSFFLLRYGRRQENSQALAIVE
KTLQSMRRGGIYDAVGFGFHRYSTDAQWRLPHFEKMLYDQALLAMAYTEAFQAAGQSLYKKTAREILTYVLRDMTAPEGG
FYSAEDADTAGEEGAFYLWTAEELRQVLPTEEAELMIRVYAIPEGGKPSVLHCSSSYPELSVDLDLPEERLLERLESARQ
KLFLQRAKRIRPLRDDKILTDWNGLMIAAMARAAAVFEEPVYLQAAREAVRFILENLRDPRGRLLHRWREGEAAMPAVLD
DYAFLIWGLIEAYEATFDANLLQTALSLDEELTAHFWDNASGGYFYTPDDGESLLVRQKESYDGAIPSGNSVAMLNLLRL
SRLTGQAGLEERAVATAQAFADSIRSLSAAHTSFMVALDYLAGPSAEVVIAGSPEGTDTRDMLRELRRAFLPHVTVLLIP
DEGEKGMLAGVAEFTGGMTRIDGRATAYVCRNFSCRKPTTDPAEMTTLLRE

Sequences:

>Translated_691_residues
MTDSTRSTGSFRNRLQQEKSPYLLQHASNPVDWYPWGEEAFEKARREDKPIFLSIGYSTCHWCHVMAHESFENEEVARLL
NESFISIKVDREERPDIDKLYMAVCQLLTGGGGWPLTILMTPDRRPFYAGTYIPRESRSGMVGMLVLIPGLSEVWRKERN
RILETAGEITTALQGMDQGGPGELPLDRVLHEAYDDLRRRFDARYGGFDSAPKFPMAQHSFFLLRYGRRQENSQALAIVE
KTLQSMRRGGIYDAVGFGFHRYSTDAQWRLPHFEKMLYDQALLAMAYTEAFQAAGQSLYKKTAREILTYVLRDMTAPEGG
FYSAEDADTAGEEGAFYLWTAEELRQVLPTEEAELMIRVYAIPEGGKPSVLHCSSSYPELSVDLDLPEERLLERLESARQ
KLFLQRAKRIRPLRDDKILTDWNGLMIAAMARAAAVFEEPVYLQAAREAVRFILENLRDPRGRLLHRWREGEAAMPAVLD
DYAFLIWGLIEAYEATFDANLLQTALSLDEELTAHFWDNASGGYFYTPDDGESLLVRQKESYDGAIPSGNSVAMLNLLRL
SRLTGQAGLEERAVATAQAFADSIRSLSAAHTSFMVALDYLAGPSAEVVIAGSPEGTDTRDMLRELRRAFLPHVTVLLIP
DEGEKGMLAGVAEFTGGMTRIDGRATAYVCRNFSCRKPTTDPAEMTTLLRE
>Mature_690_residues
TDSTRSTGSFRNRLQQEKSPYLLQHASNPVDWYPWGEEAFEKARREDKPIFLSIGYSTCHWCHVMAHESFENEEVARLLN
ESFISIKVDREERPDIDKLYMAVCQLLTGGGGWPLTILMTPDRRPFYAGTYIPRESRSGMVGMLVLIPGLSEVWRKERNR
ILETAGEITTALQGMDQGGPGELPLDRVLHEAYDDLRRRFDARYGGFDSAPKFPMAQHSFFLLRYGRRQENSQALAIVEK
TLQSMRRGGIYDAVGFGFHRYSTDAQWRLPHFEKMLYDQALLAMAYTEAFQAAGQSLYKKTAREILTYVLRDMTAPEGGF
YSAEDADTAGEEGAFYLWTAEELRQVLPTEEAELMIRVYAIPEGGKPSVLHCSSSYPELSVDLDLPEERLLERLESARQK
LFLQRAKRIRPLRDDKILTDWNGLMIAAMARAAAVFEEPVYLQAAREAVRFILENLRDPRGRLLHRWREGEAAMPAVLDD
YAFLIWGLIEAYEATFDANLLQTALSLDEELTAHFWDNASGGYFYTPDDGESLLVRQKESYDGAIPSGNSVAMLNLLRLS
RLTGQAGLEERAVATAQAFADSIRSLSAAHTSFMVALDYLAGPSAEVVIAGSPEGTDTRDMLRELRRAFLPHVTVLLIPD
EGEKGMLAGVAEFTGGMTRIDGRATAYVCRNFSCRKPTTDPAEMTTLLRE

Specific function: Unknown

COG id: COG1331

COG function: function code O; Highly conserved protein containing a thioredoxin domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To C.elegans B0495.5 [H]

Homologues:

Organism=Homo sapiens, GI31542723, Length=723, Percent_Identity=40.9405255878285, Blast_Score=528, Evalue=1e-150,
Organism=Caenorhabditis elegans, GI25147430, Length=726, Percent_Identity=34.435261707989, Blast_Score=434, Evalue=1e-122,
Organism=Drosophila melanogaster, GI20129985, Length=727, Percent_Identity=36.726272352132, Blast_Score=472, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008928
- InterPro:   IPR012341
- InterPro:   IPR010819
- InterPro:   IPR004879
- InterPro:   IPR005198
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF03190 DUF255; PF07221 GlcNAc_2-epim; PF03663 Glyco_hydro_76 [H]

EC number: NA

Molecular weight: Translated: 77916; Mature: 77785

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSTRSTGSFRNRLQQEKSPYLLQHASNPVDWYPWGEEAFEKARREDKPIFLSIGYSTC
CCCCCCCCHHHHHHHHHCCCCEEEHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHH
HWCHVMAHESFENEEVARLLNESFISIKVDREERPDIDKLYMAVCQLLTGGGGWPLTILM
HHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
TPDRRPFYAGTYIPRESRSGMVGMLVLIPGLSEVWRKERNRILETAGEITTALQGMDQGG
CCCCCCEECCCCCCCCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PGELPLDRVLHEAYDDLRRRFDARYGGFDSAPKFPMAQHSFFLLRYGRRQENSQALAIVE
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
KTLQSMRRGGIYDAVGFGFHRYSTDAQWRLPHFEKMLYDQALLAMAYTEAFQAAGQSLYK
HHHHHHHHCCCCHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTAREILTYVLRDMTAPEGGFYSAEDADTAGEEGAFYLWTAEELRQVLPTEEAELMIRVY
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCEEEEEEE
AIPEGGKPSVLHCSSSYPELSVDLDLPEERLLERLESARQKLFLQRAKRIRPLRDDKILT
EECCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
DWNGLMIAAMARAAAVFEEPVYLQAAREAVRFILENLRDPRGRLLHRWREGEAAMPAVLD
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHH
DYAFLIWGLIEAYEATFDANLLQTALSLDEELTAHFWDNASGGYFYTPDDGESLLVRQKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEECC
SYDGAIPSGNSVAMLNLLRLSRLTGQAGLEERAVATAQAFADSIRSLSAAHTSFMVALDY
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGPSAEVVIAGSPEGTDTRDMLRELRRAFLPHVTVLLIPDEGEKGMLAGVAEFTGGMTR
HCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCEE
IDGRATAYVCRNFSCRKPTTDPAEMTTLLRE
ECCCHHHHHHCCCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure 
TDSTRSTGSFRNRLQQEKSPYLLQHASNPVDWYPWGEEAFEKARREDKPIFLSIGYSTC
CCCCCCCHHHHHHHHHCCCCEEEHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCHH
HWCHVMAHESFENEEVARLLNESFISIKVDREERPDIDKLYMAVCQLLTGGGGWPLTILM
HHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEEEE
TPDRRPFYAGTYIPRESRSGMVGMLVLIPGLSEVWRKERNRILETAGEITTALQGMDQGG
CCCCCCEECCCCCCCCCCCCCEEEHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PGELPLDRVLHEAYDDLRRRFDARYGGFDSAPKFPMAQHSFFLLRYGRRQENSQALAIVE
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHH
KTLQSMRRGGIYDAVGFGFHRYSTDAQWRLPHFEKMLYDQALLAMAYTEAFQAAGQSLYK
HHHHHHHHCCCCHHHHCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KTAREILTYVLRDMTAPEGGFYSAEDADTAGEEGAFYLWTAEELRQVLPTEEAELMIRVY
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHCCCCCCEEEEEEE
AIPEGGKPSVLHCSSSYPELSVDLDLPEERLLERLESARQKLFLQRAKRIRPLRDDKILT
EECCCCCCCEEEECCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEE
DWNGLMIAAMARAAAVFEEPVYLQAAREAVRFILENLRDPRGRLLHRWREGEAAMPAVLD
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHH
DYAFLIWGLIEAYEATFDANLLQTALSLDEELTAHFWDNASGGYFYTPDDGESLLVRQKE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCEEEEEECC
SYDGAIPSGNSVAMLNLLRLSRLTGQAGLEERAVATAQAFADSIRSLSAAHTSFMVALDY
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAGPSAEVVIAGSPEGTDTRDMLRELRRAFLPHVTVLLIPDEGEKGMLAGVAEFTGGMTR
HCCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHCCCCEE
IDGRATAYVCRNFSCRKPTTDPAEMTTLLRE
ECCCHHHHHHCCCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]