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The map label for this gene is engD [H]

Identifier: 85857918

GI number: 85857918

Start: 75316

End: 76374

Strand: Direct

Name: engD [H]

Synonym: SYN_00167

Alternate gene names: 85857918

Gene position: 75316-76374 (Clockwise)

Preceding gene: 85857917

Following gene: 85857919

Centisome position: 2.37

GC content: 58.45

Gene sequence:

>1059_bases
GTGTTACTCACAAAGGAGGAATCAGCAATGGAAATCGGGATTCTGGGTCTTCCCCAGAGTGGAAAAAGCACCCTTTTCGA
AATCATGACAGGCGTCCGCAGCTGCGATGTTCATGGGGAACAGTGTGTCCGCGGACAGGCCTCCGTTCCCGACAGACGGT
TTGACCGGCTTGTGGAAATCTATAAACCCCTTCGGGCCGTGCCTGCCCGGGTTCCCTTTACGGATGTGAACGCCGCGGGT
GAAAAGGCGTGGGAAACGGTTCGCCAGGCGCTCAGCGGCGCCGAAGGCCTGCTCCATGTGGTGGACTGCTTTTCGGACAG
ATCGATTTCGGCCATGGTGAATCGCTGCCGGCAACTGGATGACGAACTGATCCTCTCCGATCTGGTGGTGGTGGAGAACC
GCCGCGAGCGGCTCTTGAAGGTGGCCAAAAAAAACCTGAAGCCGCCTGAATCTCTCCATGTGGAGCTGATGCCGCGCCTG
CAGGAGCAGCTCGAAAGCGGGAGGCCCTTGCGGGAACTGAATCTGACGGTTGAGGAACGCCATGCTCTGTCCAGTTTTTC
TTTCTGGACGCTGAGACCGGAACTGGTTGTCCTTAATGTGGCTGAAGATGGTTTCCCGACCGTGGAAGCCTTTCAGACGG
AAGCCGGGCTGGTGGAGCCGGTGATGGGGATCTGCTGCGAGCTGGAAGCGGAAGTGGCCTCTCTTCCCACTGAGGAGCAG
CAGGAATTCCTGGCGGCCCTGGGCATGGAAGAACCTGCTTTCGGACGGGTGATCCGCGCCGCCTTTTCTCTCCTCGGGCG
GATATCCTACTTTACCGTGGGAGAGGACGAGGTGAAGGCCTGGGTCATTCCGGAAGGGACAAAGGCCCCACGCGCAGCCG
CGGCCATTCACAAGGATTTTGAAAGGGGTTTCATCAAAGCCGAAGTGGTAGCTTATGATGATTTCATCGCCTGCGGCGGC
TCTCACGCCAAAGCCAAGGCGGCGGGGAAGGTCCGCCTGGAAGGCAAGGATTATATCGTGCGGGACGGCGACATCATCAC
CTTCCGATTCAACGTCTGA

Upstream 100 bases:

>100_bases
GGTTCGACGTTTAATGTTCTCACCGTAATATTCCGACCTTGAACATTGAACGTAGCGCCCCCCGTCGAGGTGGCGCTTTG
TTAGTGAGTAACTTGTTTTC

Downstream 100 bases:

>100_bases
TCTTTCTTTTTCCCTTACAGGCAAGACGAAGAGCAGACGGCCTATCATCCAAATTCTTATTGCAGAGGTTCATAATTATG
AAAATCAAATTTTTAGGCGC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MLLTKEESAMEIGILGLPQSGKSTLFEIMTGVRSCDVHGEQCVRGQASVPDRRFDRLVEIYKPLRAVPARVPFTDVNAAG
EKAWETVRQALSGAEGLLHVVDCFSDRSISAMVNRCRQLDDELILSDLVVVENRRERLLKVAKKNLKPPESLHVELMPRL
QEQLESGRPLRELNLTVEERHALSSFSFWTLRPELVVLNVAEDGFPTVEAFQTEAGLVEPVMGICCELEAEVASLPTEEQ
QEFLAALGMEEPAFGRVIRAAFSLLGRISYFTVGEDEVKAWVIPEGTKAPRAAAAIHKDFERGFIKAEVVAYDDFIACGG
SHAKAKAAGKVRLEGKDYIVRDGDIITFRFNV

Sequences:

>Translated_352_residues
MLLTKEESAMEIGILGLPQSGKSTLFEIMTGVRSCDVHGEQCVRGQASVPDRRFDRLVEIYKPLRAVPARVPFTDVNAAG
EKAWETVRQALSGAEGLLHVVDCFSDRSISAMVNRCRQLDDELILSDLVVVENRRERLLKVAKKNLKPPESLHVELMPRL
QEQLESGRPLRELNLTVEERHALSSFSFWTLRPELVVLNVAEDGFPTVEAFQTEAGLVEPVMGICCELEAEVASLPTEEQ
QEFLAALGMEEPAFGRVIRAAFSLLGRISYFTVGEDEVKAWVIPEGTKAPRAAAAIHKDFERGFIKAEVVAYDDFIACGG
SHAKAKAAGKVRLEGKDYIVRDGDIITFRFNV
>Mature_352_residues
MLLTKEESAMEIGILGLPQSGKSTLFEIMTGVRSCDVHGEQCVRGQASVPDRRFDRLVEIYKPLRAVPARVPFTDVNAAG
EKAWETVRQALSGAEGLLHVVDCFSDRSISAMVNRCRQLDDELILSDLVVVENRRERLLKVAKKNLKPPESLHVELMPRL
QEQLESGRPLRELNLTVEERHALSSFSFWTLRPELVVLNVAEDGFPTVEAFQTEAGLVEPVMGICCELEAEVASLPTEEQ
QEFLAALGMEEPAFGRVIRAAFSLLGRISYFTVGEDEVKAWVIPEGTKAPRAAAAIHKDFERGFIKAEVVAYDDFIACGG
SHAKAKAAGKVRLEGKDYIVRDGDIITFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=377, Percent_Identity=33.42175066313, Blast_Score=179, Evalue=4e-45,
Organism=Homo sapiens, GI58761502, Length=233, Percent_Identity=37.7682403433476, Blast_Score=130, Evalue=3e-30,
Organism=Escherichia coli, GI1787454, Length=366, Percent_Identity=39.6174863387978, Blast_Score=239, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17509631, Length=370, Percent_Identity=31.3513513513514, Blast_Score=177, Evalue=5e-45,
Organism=Saccharomyces cerevisiae, GI6319499, Length=382, Percent_Identity=29.3193717277487, Blast_Score=133, Evalue=5e-32,
Organism=Saccharomyces cerevisiae, GI6321773, Length=392, Percent_Identity=27.8061224489796, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24640873, Length=375, Percent_Identity=32, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24640877, Length=375, Percent_Identity=32, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24640875, Length=375, Percent_Identity=32, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24640879, Length=330, Percent_Identity=32.7272727272727, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39040; Mature: 39040

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLTKEESAMEIGILGLPQSGKSTLFEIMTGVRSCDVHGEQCVRGQASVPDRRFDRLVEI
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHH
YKPLRAVPARVPFTDVNAAGEKAWETVRQALSGAEGLLHVVDCFSDRSISAMVNRCRQLD
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
DELILSDLVVVENRRERLLKVAKKNLKPPESLHVELMPRLQEQLESGRPLRELNLTVEER
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHH
HALSSFSFWTLRPELVVLNVAEDGFPTVEAFQTEAGLVEPVMGICCELEAEVASLPTEEQ
HHHHCCCEEEECCEEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCHHH
QEFLAALGMEEPAFGRVIRAAFSLLGRISYFTVGEDEVKAWVIPEGTKAPRAAAAIHKDF
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCCCHHHHHHHHHH
ERGFIKAEVVAYDDFIACGGSHAKAKAAGKVRLEGKDYIVRDGDIITFRFNV
HHCCEEEEEEEECCHHHCCCCCCCHHCCCEEEECCCCEEEECCCEEEEEECC
>Mature Secondary Structure
MLLTKEESAMEIGILGLPQSGKSTLFEIMTGVRSCDVHGEQCVRGQASVPDRRFDRLVEI
CCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHH
YKPLRAVPARVPFTDVNAAGEKAWETVRQALSGAEGLLHVVDCFSDRSISAMVNRCRQLD
HHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHH
DELILSDLVVVENRRERLLKVAKKNLKPPESLHVELMPRLQEQLESGRPLRELNLTVEER
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHH
HALSSFSFWTLRPELVVLNVAEDGFPTVEAFQTEAGLVEPVMGICCELEAEVASLPTEEQ
HHHHCCCEEEECCEEEEEEECCCCCCCHHHHHHHCCHHHHHHHHHHHCCHHHHHCCCHHH
QEFLAALGMEEPAFGRVIRAAFSLLGRISYFTVGEDEVKAWVIPEGTKAPRAAAAIHKDF
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHEEEECCCCEEEEECCCCCCCCHHHHHHHHHH
ERGFIKAEVVAYDDFIACGGSHAKAKAAGKVRLEGKDYIVRDGDIITFRFNV
HHCCEEEEEEEECCHHHCCCCCCCHHCCCEEEECCCCEEEECCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]