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The map label for this gene is adh [H]

Identifier: 85375741

GI number: 85375741

Start: 2932628

End: 2934799

Strand: Reverse

Name: adh [H]

Synonym: ELI_14570

Alternate gene names: 85375741

Gene position: 2934799-2932628 (Counterclockwise)

Preceding gene: 85375744

Following gene: 85375735

Centisome position: 96.15

GC content: 64.78

Gene sequence:

>2172_bases
ATGCGGAAATGGACCACGGCACTGGCCGGGATCGCGGTGTTGTCGCTGGGCGGGATCACGCTCGCTGCCTGCAATAGCGG
GGAGGAAATGGTCGAAGGCGGTATCGACAATATCCGCCTGATGAATGCCGATGCCGACAGCGCCAATTGGATCACGCATG
GCCGGACCTATTCCGAACAGCGCTTTTCCCCGCTGAGCCAGGTCAACCAGGAAACGGTCGGCGAGCTGGGCCTCGCCTGG
TATGCCGACATGGACACCGCGCGCGGGCAAGAAGCGACGCCGCTGGTGATGGACGGCAAGCTCTACCTCACCACCGCCTG
GAGCAAGGTGAAGGCTTTCGACGCCGCGACGGGCGAGCCATTGTGGGAATACGATCCGCAAGTACCCGGCGAGACGGCGG
TCAAGGCGTGCTGCGATGTCGTCAACCGCGGGCTCGCGGCGTGGAACGACAAACTCTACCTCGGCACGCTCGACGGGCGG
CTGGTCGCGCTCGACCGCGATACCGGCGAGGTCGCGTGGGAAAAGGTCACCGTCGACCAGTCCAAGGCCTACACCGTCAC
CGGCGCGCCGCGGATTATCGACGGCAAGGTGCTGATCGGCAATGGCGGGGCTGAATTTGGCGTGCGCGGCTATATCGCGG
CCTATGATGCCGCCGACGGCGAGGAGCTGTGGCGCTTCTACACCGTCCCCGAAGGCACCGAGGATGAGAGCTCGCCTGCC
TATTTGCAGGAAGCAGCGGCGACATGGAACACCGATGTCCTTGCCAGTTCCGACGCCATCGGCGGCGGCGGCACGGTATG
GGATTCGATGGCCTACGACCCGGAGCTCGACCTGCTCTATATCGGCGTCGGCAACGGCAGCCCGTGGAACCGGGCCTATC
GCAGCCCCGGCGCCGACGGCACGGGCGAAGGCGACAACCTCTATCTCTCCAGCATCGTGGCGATCCGTCCCGACACCGGC
GAGTATGTCTGGCATTACCAGACGACGCCGGGCGAAACCTGGGACTACACTGCGACCCAGCACATCATCCTCGCGGATCT
CGAGATCGACGGGCGCGAGCGCCAGGTGTTGATGCAGGCCCCCAAGAACGGCTTCTTCTACGTCATCGACCGGGCCACCG
GCGAATTCATCAGCGCGGAAGAATATATCCCGCAGAACTGGGCCGAAGGGATCGACGAGAACGGTCGTCCGATCGAAGTC
GCCGAAGCACGCATCGACAAGACCGGCGAACCAGCTTTGGTTATGCCGGGGCCCCTTGGCGGCCATAACTGGCACCCTAT
GGCGTTCCACCCGGGCGAAGGACTGGTCTATATTCCCGCCTTCGAAGCGGCGACGATCTACGATCCGGAGCCCGACTGGA
AGCCCGACCCGGCGCGCGGTTTCAATGTCGGCTTCAATTTGGGCGCAGGCGATCTGCCGCCCGACATGGGCATCCGCAAA
CAGGTCTACGGCACCGTCAAAGGCAAGCTGATGGCGTGGGACCCGGTCGCGCAGGAAGCGCGCTGGACGGTCGAATTTCC
CGGGCCGTGGAATGGCGGCATCCTCGCCACCGGCGGTGGCCTGGTGTTCCAGGGCAATTCGGGCAGCGAATTCGCGGCCT
ATGATGCGTCGACTGGTGAGAAATTGTGGGGCTTCCCGGCACAGACCGGCATCGTCGCTCCGCCGATCACCTACACCGTC
GATGGCGAGCAATTTGTCGCCGTGCTGGCCGGATGGGGCGGGGCCTACGCCATCACCGCCGACGGCGAGTTGGTCAACGA
CCAGGGGCCGGTCCAGAACATCAGCCGCCTGCTGGTGTTCAAGATCGGCGGCACGGGCGAATTGCCCGAGCAACCCGAGC
TGGCGCGCCTGCCGCTCGACCCTCCGCCAAGCCGAGCCAGCGCGGAAGTGATCGCGCTCGGCAAGGAAAAATACGCTCGC
TATTGCGCGGTCTGCCACGCCCCGGCGGCGGTAGGCTCGACCGTCCTGCCCGACCTGCGACGCTCGGCAACGCTCGCGAA
CAAGCAGGCCTGGCTCGCCGTCGTCCACCAAGGCATCCTCAAGGACAATGGCATGGTCAGCTTCGCGGATTCACTCAGCG
AGGAAGAAATCGACGCGATCCGCGAATACGTGATCAAGCGCGCCAACGAAGACAAGGCTATCGAGCGTCCGGCACAGGTG
GCAAGGCGCTAG

Upstream 100 bases:

>100_bases
TTCCCCCCATGGACAAGCGCGGTCTGGTTGGGCAGAACCGGTAGCACATCAAAACCGGAACGGGCAGGCAAGCCCGCGCG
GTCTCTGGGGAGAGGGTATC

Downstream 100 bases:

>100_bases
GGGACTAAAGCGCTTCCTCGTAAAGTGCGAGCAAGCGGCTCCACGCCTTTTCTGCAGGCCCTTCGACGTAAGCGGGATTG
TCCGGCACGGTCCAGCCGTG

Product: alcohol dehydrogenase large subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 723; Mature: 723

Protein sequence:

>723_residues
MRKWTTALAGIAVLSLGGITLAACNSGEEMVEGGIDNIRLMNADADSANWITHGRTYSEQRFSPLSQVNQETVGELGLAW
YADMDTARGQEATPLVMDGKLYLTTAWSKVKAFDAATGEPLWEYDPQVPGETAVKACCDVVNRGLAAWNDKLYLGTLDGR
LVALDRDTGEVAWEKVTVDQSKAYTVTGAPRIIDGKVLIGNGGAEFGVRGYIAAYDAADGEELWRFYTVPEGTEDESSPA
YLQEAAATWNTDVLASSDAIGGGGTVWDSMAYDPELDLLYIGVGNGSPWNRAYRSPGADGTGEGDNLYLSSIVAIRPDTG
EYVWHYQTTPGETWDYTATQHIILADLEIDGRERQVLMQAPKNGFFYVIDRATGEFISAEEYIPQNWAEGIDENGRPIEV
AEARIDKTGEPALVMPGPLGGHNWHPMAFHPGEGLVYIPAFEAATIYDPEPDWKPDPARGFNVGFNLGAGDLPPDMGIRK
QVYGTVKGKLMAWDPVAQEARWTVEFPGPWNGGILATGGGLVFQGNSGSEFAAYDASTGEKLWGFPAQTGIVAPPITYTV
DGEQFVAVLAGWGGAYAITADGELVNDQGPVQNISRLLVFKIGGTGELPEQPELARLPLDPPPSRASAEVIALGKEKYAR
YCAVCHAPAAVGSTVLPDLRRSATLANKQAWLAVVHQGILKDNGMVSFADSLSEEEIDAIREYVIKRANEDKAIERPAQV
ARR

Sequences:

>Translated_723_residues
MRKWTTALAGIAVLSLGGITLAACNSGEEMVEGGIDNIRLMNADADSANWITHGRTYSEQRFSPLSQVNQETVGELGLAW
YADMDTARGQEATPLVMDGKLYLTTAWSKVKAFDAATGEPLWEYDPQVPGETAVKACCDVVNRGLAAWNDKLYLGTLDGR
LVALDRDTGEVAWEKVTVDQSKAYTVTGAPRIIDGKVLIGNGGAEFGVRGYIAAYDAADGEELWRFYTVPEGTEDESSPA
YLQEAAATWNTDVLASSDAIGGGGTVWDSMAYDPELDLLYIGVGNGSPWNRAYRSPGADGTGEGDNLYLSSIVAIRPDTG
EYVWHYQTTPGETWDYTATQHIILADLEIDGRERQVLMQAPKNGFFYVIDRATGEFISAEEYIPQNWAEGIDENGRPIEV
AEARIDKTGEPALVMPGPLGGHNWHPMAFHPGEGLVYIPAFEAATIYDPEPDWKPDPARGFNVGFNLGAGDLPPDMGIRK
QVYGTVKGKLMAWDPVAQEARWTVEFPGPWNGGILATGGGLVFQGNSGSEFAAYDASTGEKLWGFPAQTGIVAPPITYTV
DGEQFVAVLAGWGGAYAITADGELVNDQGPVQNISRLLVFKIGGTGELPEQPELARLPLDPPPSRASAEVIALGKEKYAR
YCAVCHAPAAVGSTVLPDLRRSATLANKQAWLAVVHQGILKDNGMVSFADSLSEEEIDAIREYVIKRANEDKAIERPAQV
ARR
>Mature_723_residues
MRKWTTALAGIAVLSLGGITLAACNSGEEMVEGGIDNIRLMNADADSANWITHGRTYSEQRFSPLSQVNQETVGELGLAW
YADMDTARGQEATPLVMDGKLYLTTAWSKVKAFDAATGEPLWEYDPQVPGETAVKACCDVVNRGLAAWNDKLYLGTLDGR
LVALDRDTGEVAWEKVTVDQSKAYTVTGAPRIIDGKVLIGNGGAEFGVRGYIAAYDAADGEELWRFYTVPEGTEDESSPA
YLQEAAATWNTDVLASSDAIGGGGTVWDSMAYDPELDLLYIGVGNGSPWNRAYRSPGADGTGEGDNLYLSSIVAIRPDTG
EYVWHYQTTPGETWDYTATQHIILADLEIDGRERQVLMQAPKNGFFYVIDRATGEFISAEEYIPQNWAEGIDENGRPIEV
AEARIDKTGEPALVMPGPLGGHNWHPMAFHPGEGLVYIPAFEAATIYDPEPDWKPDPARGFNVGFNLGAGDLPPDMGIRK
QVYGTVKGKLMAWDPVAQEARWTVEFPGPWNGGILATGGGLVFQGNSGSEFAAYDASTGEKLWGFPAQTGIVAPPITYTV
DGEQFVAVLAGWGGAYAITADGELVNDQGPVQNISRLLVFKIGGTGELPEQPELARLPLDPPPSRASAEVIALGKEKYAR
YCAVCHAPAAVGSTVLPDLRRSATLANKQAWLAVVHQGILKDNGMVSFADSLSEEEIDAIREYVIKRANEDKAIERPAQV
ARR

Specific function: Catalyzes the oxidation of primary alcohols except for methanol that is not a substrate [H]

COG id: COG4993

COG function: function code G; Glucose dehydrogenase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 cytochrome c domain [H]

Homologues:

Organism=Escherichia coli, GI1786316, Length=381, Percent_Identity=29.3963254593176, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009056
- InterPro:   IPR003088
- InterPro:   IPR019556
- InterPro:   IPR019551
- InterPro:   IPR018391
- InterPro:   IPR017512
- InterPro:   IPR002372
- InterPro:   IPR011047
- InterPro:   IPR001479 [H]

Pfam domain/function: PF00034 Cytochrom_C; PF01011 PQQ; PF10535 PQQ_C; PF10527 PQQ_N [H]

EC number: =1.1.2.8 [H]

Molecular weight: Translated: 77995; Mature: 77995

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00364 BACTERIAL_PQQ_2 ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKWTTALAGIAVLSLGGITLAACNSGEEMVEGGIDNIRLMNADADSANWITHGRTYSEQ
CCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCCEEEEECCCCCCCCEECCCCCCHH
RFSPLSQVNQETVGELGLAWYADMDTARGQEATPLVMDGKLYLTTAWSKVKAFDAATGEP
HCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCEEECCEEEEEECCHHHEEECCCCCCC
LWEYDPQVPGETAVKACCDVVNRGLAAWNDKLYLGTLDGRLVALDRDTGEVAWEKVTVDQ
CCCCCCCCCCHHHHHHHHHHHHCCHHHCCCEEEEEECCCEEEEEECCCCCEEEEEEEECC
SKAYTVTGAPRIIDGKVLIGNGGAEFGVRGYIAAYDAADGEELWRFYTVPEGTEDESSPA
CCEEEECCCCEEEECEEEEECCCCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCH
YLQEAAATWNTDVLASSDAIGGGGTVWDSMAYDPELDLLYIGVGNGSPWNRAYRSPGADG
HHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCCC
TGEGDNLYLSSIVAIRPDTGEYVWHYQTTPGETWDYTATQHIILADLEIDGRERQVLMQA
CCCCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCHHHEEEC
PKNGFFYVIDRATGEFISAEEYIPQNWAEGIDENGRPIEVAEARIDKTGEPALVMPGPLG
CCCCEEEEEECCCCCEECHHHHCCCHHHHCCCCCCCEEEEEHHHCCCCCCCEEEECCCCC
GHNWHPMAFHPGEGLVYIPAFEAATIYDPEPDWKPDPARGFNVGFNLGAGDLPPDMGIRK
CCCCCCCEEECCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHH
QVYGTVKGKLMAWDPVAQEARWTVEFPGPWNGGILATGGGLVFQGNSGSEFAAYDASTGE
HHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCEEEECCCEEEECCCCCCEEEECCCCCC
KLWGFPAQTGIVAPPITYTVDGEQFVAVLAGWGGAYAITADGELVNDQGPVQNISRLLVF
HHCCCCCCCCEECCCEEEEECCCEEEEEEECCCCEEEEEECCCEECCCCCHHHHCEEEEE
KIGGTGELPEQPELARLPLDPPPSRASAEVIALGKEKYARYCAVCHAPAAVGSTVLPDLR
EECCCCCCCCCCCCEECCCCCCCCCCCCEEEEECHHHHHHHHHHHCCHHHHCCHHHHHHH
RSATLANKQAWLAVVHQGILKDNGMVSFADSLSEEEIDAIREYVIKRANEDKAIERPAQV
HHHHHHCHHHHHHHHHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
ARR
HCC
>Mature Secondary Structure
MRKWTTALAGIAVLSLGGITLAACNSGEEMVEGGIDNIRLMNADADSANWITHGRTYSEQ
CCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHCCCCCEEEEECCCCCCCCEECCCCCCHH
RFSPLSQVNQETVGELGLAWYADMDTARGQEATPLVMDGKLYLTTAWSKVKAFDAATGEP
HCCHHHHHHHHHHHHHCEEEEECCCCCCCCCCCCEEECCEEEEEECCHHHEEECCCCCCC
LWEYDPQVPGETAVKACCDVVNRGLAAWNDKLYLGTLDGRLVALDRDTGEVAWEKVTVDQ
CCCCCCCCCCHHHHHHHHHHHHCCHHHCCCEEEEEECCCEEEEEECCCCCEEEEEEEECC
SKAYTVTGAPRIIDGKVLIGNGGAEFGVRGYIAAYDAADGEELWRFYTVPEGTEDESSPA
CCEEEECCCCEEEECEEEEECCCCCCCCEEEEEEECCCCCHHEEEEEECCCCCCCCCCCH
YLQEAAATWNTDVLASSDAIGGGGTVWDSMAYDPELDLLYIGVGNGSPWNRAYRSPGADG
HHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHCCCCCCC
TGEGDNLYLSSIVAIRPDTGEYVWHYQTTPGETWDYTATQHIILADLEIDGRERQVLMQA
CCCCCCEEEEEEEEECCCCCCEEEEEECCCCCCCCCCCCCEEEEEEEEECCCCHHHEEEC
PKNGFFYVIDRATGEFISAEEYIPQNWAEGIDENGRPIEVAEARIDKTGEPALVMPGPLG
CCCCEEEEEECCCCCEECHHHHCCCHHHHCCCCCCCEEEEEHHHCCCCCCCEEEECCCCC
GHNWHPMAFHPGEGLVYIPAFEAATIYDPEPDWKPDPARGFNVGFNLGAGDLPPDMGIRK
CCCCCCCEEECCCCEEEEECCCEEEEECCCCCCCCCCCCCCCCEEECCCCCCCCCCCCHH
QVYGTVKGKLMAWDPVAQEARWTVEFPGPWNGGILATGGGLVFQGNSGSEFAAYDASTGE
HHHHHCCCEEEEECCCCCCCEEEEECCCCCCCCEEEECCCEEEECCCCCCEEEECCCCCC
KLWGFPAQTGIVAPPITYTVDGEQFVAVLAGWGGAYAITADGELVNDQGPVQNISRLLVF
HHCCCCCCCCEECCCEEEEECCCEEEEEEECCCCEEEEEECCCEECCCCCHHHHCEEEEE
KIGGTGELPEQPELARLPLDPPPSRASAEVIALGKEKYARYCAVCHAPAAVGSTVLPDLR
EECCCCCCCCCCCCEECCCCCCCCCCCCEEEEECHHHHHHHHHHHCCHHHHCCHHHHHHH
RSATLANKQAWLAVVHQGILKDNGMVSFADSLSEEEIDAIREYVIKRANEDKAIERPAQV
HHHHHHCHHHHHHHHHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHH
ARR
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA