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The map label for this gene is crp [C]

Identifier: 85375638

GI number: 85375638

Start: 2828112

End: 2828741

Strand: Reverse

Name: crp [C]

Synonym: ELI_14055

Alternate gene names: 85375638

Gene position: 2828741-2828112 (Counterclockwise)

Preceding gene: 85375641

Following gene: 85375636

Centisome position: 92.67

GC content: 69.84

Gene sequence:

>630_bases
GTGGCGCCGACGCTGTTCGGCCTGCTCGACGAAAGTCTGCGCGAGGCCCTGCGCGCGGCCGCGCCCGAGCGTCGGTTCGC
GCCGGGACAGGTGATCCAGCAGCGCGGCGAAGCGACCAGCGGCTTCTGGGTGATCGAGCGCGGCGCGGTGGTGGTGGGCC
AGTATCTGGAGAGCGGCGACTTCCGCGCCATCGCCCATCTCGGCGAACGCGATTCCTACGGCGAGCTGGCGTGGCTGGCC
GGCCGGACGCGGGTCGTCGATGCGGTCGCGCGCACCGAATGTTCGCTGCGCTGGATCGAAGGCGCACGCTTCGAAGCGGC
GCTGGCAAACAACCCCAGCGCGATGCGGCAATTGCTGAGCGGGCTGGCGGAAGAATTGCAGGAGATGATCGACTTGGTCG
CCGGGCAGCATGGGGGCAGAGGGCTCAACCGGATCGCGCATTTCCTGCGCAATCTCTCCGCCACCGGCCCGGTGATCGCG
ATGGGGCAGCAGGAACTGGGCGACCTGGCCGGCGTCACCCGCGCAACCGCCAATGCCGCGCTCAAGACGCTCGAGCAGGC
GGGCTGTATCGAGCGCGGGTACCGCCGGATTGTGGTGAAGGACCGCGAGCGTCTGGCGGACTGGGCCTAG

Upstream 100 bases:

>100_bases
CAGTCGGCATGATCCACTCCCTTGTTGGAAGCCGGATAGCGCGCTATCGCAATCGGGAATGTCAGATTCTATACAATCGC
GCGCCGAGGGCCGGTCGGTT

Downstream 100 bases:

>100_bases
CGGGCCGGAGCCGGTGCTTCGCGTTCCGCGCCCGCACACGGATCTTCGTCGTCGCCGCCGCCGCCCAGCTGCGTGATGGC
GAGTACCCCGCCCACGACCA

Product: cyclic nucleotide-binding

Products: NA

Alternate protein names: CAMP-Dependent Transcriptional Regulator; Transcriptional Regulator Crp/Fnr Family

Number of amino acids: Translated: 209; Mature: 208

Protein sequence:

>209_residues
MAPTLFGLLDESLREALRAAAPERRFAPGQVIQQRGEATSGFWVIERGAVVVGQYLESGDFRAIAHLGERDSYGELAWLA
GRTRVVDAVARTECSLRWIEGARFEAALANNPSAMRQLLSGLAEELQEMIDLVAGQHGGRGLNRIAHFLRNLSATGPVIA
MGQQELGDLAGVTRATANAALKTLEQAGCIERGYRRIVVKDRERLADWA

Sequences:

>Translated_209_residues
MAPTLFGLLDESLREALRAAAPERRFAPGQVIQQRGEATSGFWVIERGAVVVGQYLESGDFRAIAHLGERDSYGELAWLA
GRTRVVDAVARTECSLRWIEGARFEAALANNPSAMRQLLSGLAEELQEMIDLVAGQHGGRGLNRIAHFLRNLSATGPVIA
MGQQELGDLAGVTRATANAALKTLEQAGCIERGYRRIVVKDRERLADWA
>Mature_208_residues
APTLFGLLDESLREALRAAAPERRFAPGQVIQQRGEATSGFWVIERGAVVVGQYLESGDFRAIAHLGERDSYGELAWLAG
RTRVVDAVARTECSLRWIEGARFEAALANNPSAMRQLLSGLAEELQEMIDLVAGQHGGRGLNRIAHFLRNLSATGPVIAM
GQQELGDLAGVTRATANAALKTLEQAGCIERGYRRIVVKDRERLADWA

Specific function: This Protein Complexes With Cyclic AMP And Binds To Specific DNA Sites Near The Promoter To Regulate The Transcription Of Several Catabolite-Sensitive Operons. The Protein Induces A Severe Bend In The DNA. Acts As A Negative Regulator Of Its Own Synthesi

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 22767; Mature: 22636

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPTLFGLLDESLREALRAAAPERRFAPGQVIQQRGEATSGFWVIERGAVVVGQYLESGD
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCC
FRAIAHLGERDSYGELAWLAGRTRVVDAVARTECSLRWIEGARFEAALANNPSAMRQLLS
HHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHH
GLAEELQEMIDLVAGQHGGRGLNRIAHFLRNLSATGPVIAMGQQELGDLAGVTRATANAA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHH
LKTLEQAGCIERGYRRIVVKDRERLADWA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
APTLFGLLDESLREALRAAAPERRFAPGQVIQQRGEATSGFWVIERGAVVVGQYLESGD
CCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHCCCCCCCEEEEECCHHHHHHHHCCCC
FRAIAHLGERDSYGELAWLAGRTRVVDAVARTECSLRWIEGARFEAALANNPSAMRQLLS
HHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHH
GLAEELQEMIDLVAGQHGGRGLNRIAHFLRNLSATGPVIAMGQQELGDLAGVTRATANAA
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHHHHHH
LKTLEQAGCIERGYRRIVVKDRERLADWA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA