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The map label for this gene is lspA [H]

Identifier: 85375536

GI number: 85375536

Start: 2729017

End: 2729571

Strand: Reverse

Name: lspA [H]

Synonym: ELI_13545

Alternate gene names: 85375536

Gene position: 2729571-2729017 (Counterclockwise)

Preceding gene: 85375537

Following gene: 85375535

Centisome position: 89.42

GC content: 60.54

Gene sequence:

>555_bases
ATGACCATAACGACGCAACAGGTCTGGAAGCGCCGCCTGGTCGGCTTCGCGCTGGCGCTGGCGATCCTCGCCGCCGACCA
GTATGTGAAATGGCTCGTGCGCGTGCAGCTCGATCTACGCAGCCGGCCAGAGGGTCTGTACGAGCTACTGCCGTTCTTCG
ACCTGCGATGGACGCAGAATTTCGGTATTTCGCTGGGCATGTTCGAAGCGACCAGCGTGGAGATGCGCTGGGCGCTGGTG
CTCGGAACCGCGCTGATCGCAGTCGTCGTCGGCATCTGGATGCTGCGCGAGAAAACGCTCGGCGACATTATCGGCCTCGG
CCTTATCTTCGGCGGCGCGCTCGGCAATATCTACGATCGCTACACCTGGGGCTATGTAATCGACTATGCCGACCTGCATT
TCGGGGAATTCCGCCCCTTCCTGATCTTCAACATTGCCGATGCCGCGATTACCATCGGCGTGCTGATTATCCTTGCCCGC
TCGTTCCTCGTGCCCGAAAAGAAGACTACGACGAGCGAACCCGACAAGTCGGCCGAAGTGCCGGCGGAGAGTTGA

Upstream 100 bases:

>100_bases
AATCCAAATGCGGCCGCTGCTGGCGCCTGCTTCCTGATGTCGAGGAAGACGGCGATTTGTGCGACCGCTGCGACGACGTG
GTCGGGGAGGTCGCCGCCCG

Downstream 100 bases:

>100_bases
GAGACATGACAAAGATTTCCTCCCTGATCCTGCTCGCTTCCGGCGGCGCCATGCTCGCATCCTGCGCTAGCGGCGGTATC
CTCAATCGCGACCGGCCCGA

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 184; Mature: 183

Protein sequence:

>184_residues
MTITTQQVWKRRLVGFALALAILAADQYVKWLVRVQLDLRSRPEGLYELLPFFDLRWTQNFGISLGMFEATSVEMRWALV
LGTALIAVVVGIWMLREKTLGDIIGLGLIFGGALGNIYDRYTWGYVIDYADLHFGEFRPFLIFNIADAAITIGVLIILAR
SFLVPEKKTTTSEPDKSAEVPAES

Sequences:

>Translated_184_residues
MTITTQQVWKRRLVGFALALAILAADQYVKWLVRVQLDLRSRPEGLYELLPFFDLRWTQNFGISLGMFEATSVEMRWALV
LGTALIAVVVGIWMLREKTLGDIIGLGLIFGGALGNIYDRYTWGYVIDYADLHFGEFRPFLIFNIADAAITIGVLIILAR
SFLVPEKKTTTSEPDKSAEVPAES
>Mature_183_residues
TITTQQVWKRRLVGFALALAILAADQYVKWLVRVQLDLRSRPEGLYELLPFFDLRWTQNFGISLGMFEATSVEMRWALVL
GTALIAVVVGIWMLREKTLGDIIGLGLIFGGALGNIYDRYTWGYVIDYADLHFGEFRPFLIFNIADAAITIGVLIILARS
FLVPEKKTTTSEPDKSAEVPAES

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=123, Percent_Identity=34.1463414634146, Blast_Score=68, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 20690; Mature: 20558

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTITTQQVWKRRLVGFALALAILAADQYVKWLVRVQLDLRSRPEGLYELLPFFDLRWTQN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCEECCC
FGISLGMFEATSVEMRWALVLGTALIAVVVGIWMLREKTLGDIIGLGLIFGGALGNIYDR
CCCEEECEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTWGYVIDYADLHFGEFRPFLIFNIADAAITIGVLIILARSFLVPEKKTTTSEPDKSAEV
HHCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PAES
CCCC
>Mature Secondary Structure 
TITTQQVWKRRLVGFALALAILAADQYVKWLVRVQLDLRSRPEGLYELLPFFDLRWTQN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCEECCC
FGISLGMFEATSVEMRWALVLGTALIAVVVGIWMLREKTLGDIIGLGLIFGGALGNIYDR
CCCEEECEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YTWGYVIDYADLHFGEFRPFLIFNIADAAITIGVLIILARSFLVPEKKTTTSEPDKSAEV
HHCCEEEEECCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
PAES
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA