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The map label for this gene is wza [H]

Identifier: 85375505

GI number: 85375505

Start: 2699277

End: 2699996

Strand: Reverse

Name: wza [H]

Synonym: ELI_13390

Alternate gene names: 85375505

Gene position: 2699996-2699277 (Counterclockwise)

Preceding gene: 85375506

Following gene: 85375504

Centisome position: 88.45

GC content: 61.39

Gene sequence:

>720_bases
ATGCTTCGAATTACTGTACTGATTTCGGCCGTGCTCCTGGCCGCCTGCGCCGGACGCGAACCGATACAATCGACTGCCGA
CCTGACTGTCGTCGAAGGCGTCTCCGAACTGCCGATGCCCGTCCGTTCGGACCTGGTGGCGCCTGATCGTCTGGCCCTGA
TCGGTCCGCTCGACACCATCAATGTCGATGTTTTCGGGGTGAGGGAGCTCAGCCGCGAAGTTCAGGTCGACAGCAGCGGG
CGCATTTCGATGCCGCTGGTCGGAACGCTTGAGGCCGGTGGCAAGACGTCGAGCGAACTCGCAAAGGACATCGAGGGCGA
ACTGGCCGGACGCTATGTCCGCAACCCGCAAGTCACCGTGAATATCCGCAGTTCGGTCAGCCAGTTCGTGGCGATCGACG
GGCAGGTCGTCGAACCGGGTCTCTATCCGGTGACCAACCAGCTCACCTTGATGCGCGCAATCGCATCGGCGAAGGGCCTG
ACGGAGTTCGCGCGTCAGGATGATGTCGTGATCTTGCGCACCGTGGATGGCCAGCGGATGGCCGGGCTTTACAATATCGG
TGCAATCCGCCGCGGGGTTTATGCAGACCCGGAAATCTACGCGAACGACGTCGTCGTCGTTGGCGATTCGCCGCAACGAC
GCAGGTTCCGCGACTTTGTCGCACTGTCGCCGCTCCTGGCATCGCCCTTGGTCGCAATTCTAAACAGTGGTTCGAACTGA

Upstream 100 bases:

>100_bases
AGGGCCGAAGCGCAATAGAGTATGATGAGTACGCGCATTGGTGGGTAGGCGCGACGAGAAGGGTTAATCTGCGAGACAAT
CGGGATTGTTAAACATAGTC

Downstream 100 bases:

>100_bases
TCATGAATGTTGTTCAAGCGGAATTGGGCGGCGAAGCTAGCCCTGTGGCCAATCAGGTCGCGATGGGCGCTGGAAACGTG
CCCATGGGTGGTGCCCGCGC

Product: GumB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MLRITVLISAVLLAACAGREPIQSTADLTVVEGVSELPMPVRSDLVAPDRLALIGPLDTINVDVFGVRELSREVQVDSSG
RISMPLVGTLEAGGKTSSELAKDIEGELAGRYVRNPQVTVNIRSSVSQFVAIDGQVVEPGLYPVTNQLTLMRAIASAKGL
TEFARQDDVVILRTVDGQRMAGLYNIGAIRRGVYADPEIYANDVVVVGDSPQRRRFRDFVALSPLLASPLVAILNSGSN

Sequences:

>Translated_239_residues
MLRITVLISAVLLAACAGREPIQSTADLTVVEGVSELPMPVRSDLVAPDRLALIGPLDTINVDVFGVRELSREVQVDSSG
RISMPLVGTLEAGGKTSSELAKDIEGELAGRYVRNPQVTVNIRSSVSQFVAIDGQVVEPGLYPVTNQLTLMRAIASAKGL
TEFARQDDVVILRTVDGQRMAGLYNIGAIRRGVYADPEIYANDVVVVGDSPQRRRFRDFVALSPLLASPLVAILNSGSN
>Mature_239_residues
MLRITVLISAVLLAACAGREPIQSTADLTVVEGVSELPMPVRSDLVAPDRLALIGPLDTINVDVFGVRELSREVQVDSSG
RISMPLVGTLEAGGKTSSELAKDIEGELAGRYVRNPQVTVNIRSSVSQFVAIDGQVVEPGLYPVTNQLTLMRAIASAKGL
TEFARQDDVVILRTVDGQRMAGLYNIGAIRRGVYADPEIYANDVVVVGDSPQRRRFRDFVALSPLLASPLVAILNSGSN

Specific function: Probably involved in the export of the extracellular polysaccharide colanic acid from the cell to medium [H]

COG id: COG1596

COG function: function code M; Periplasmic protein involved in polysaccharide export

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BexD/CtrA/VexA family [H]

Homologues:

Organism=Escherichia coli, GI1788376, Length=140, Percent_Identity=35, Blast_Score=67, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003715
- InterPro:   IPR019554 [H]

Pfam domain/function: PF02563 Poly_export; PF10531 SLBB [H]

EC number: NA

Molecular weight: Translated: 25569; Mature: 25569

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRITVLISAVLLAACAGREPIQSTADLTVVEGVSELPMPVRSDLVAPDRLALIGPLDTI
CEEHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHCCCCHHHCCCCCCCEEEECCCCEE
NVDVFGVRELSREVQVDSSGRISMPLVGTLEAGGKTSSELAKDIEGELAGRYVRNPQVTV
EEEEEEHHHHHHHHCCCCCCCEECCEEEEECCCCCCHHHHHHHHHHHHHCCEECCCEEEE
NIRSSVSQFVAIDGQVVEPGLYPVTNQLTLMRAIASAKGLTEFARQDDVVILRTVDGQRM
EEHHHHHHHHEECCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
AGLYNIGAIRRGVYADPEIYANDVVVVGDSPQRRRFRDFVALSPLLASPLVAILNSGSN
HHHHHHHHHHCCCCCCCCEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLRITVLISAVLLAACAGREPIQSTADLTVVEGVSELPMPVRSDLVAPDRLALIGPLDTI
CEEHHHHHHHHHHHHHCCCCCCCCCCCCCEECCHHHCCCCHHHCCCCCCCEEEECCCCEE
NVDVFGVRELSREVQVDSSGRISMPLVGTLEAGGKTSSELAKDIEGELAGRYVRNPQVTV
EEEEEEHHHHHHHHCCCCCCCEECCEEEEECCCCCCHHHHHHHHHHHHHCCEECCCEEEE
NIRSSVSQFVAIDGQVVEPGLYPVTNQLTLMRAIASAKGLTEFARQDDVVILRTVDGQRM
EEHHHHHHHHEECCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHH
AGLYNIGAIRRGVYADPEIYANDVVVVGDSPQRRRFRDFVALSPLLASPLVAILNSGSN
HHHHHHHHHHCCCCCCCCEEECCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]