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The map label for this gene is eryC1 [H]

Identifier: 85375498

GI number: 85375498

Start: 2690276

End: 2691373

Strand: Direct

Name: eryC1 [H]

Synonym: ELI_13355

Alternate gene names: 85375498

Gene position: 2690276-2691373 (Clockwise)

Preceding gene: 85375497

Following gene: 85375499

Centisome position: 88.14

GC content: 58.83

Gene sequence:

>1098_bases
GTGGTGAAGTTTCTCGACCTCGTCGGTCAATACAACGAGATCAAAGACGAAATCGATGTCGCGATCGCACGCGTTATCGG
TTCTGCCGCCTATATCGGCGGCCCGGACCTGACGGCATTCGAGGAAGAATTTGCCGATTTCCAGCAAGCGCAGCACTGCG
TCGGCGTCGCCAATGGCACTGACGCGCTCGAAATCGCCATCGAGGCGCTCGATCTGCCCTCGGGTTCGGAAATTCTCGTT
CCGGCCAACAGCTTCGTGGCGAGCTCCGAAGCAGTGACCCGCAGCGGCCATCGGGTGCTGTTCTGTGAAGCCGATGCGGT
CAGTTACACAATCGATCTCGATGACGCGGCCCATCGCGTAACCGAAAAGACCAAGGCCATGATCGTGGTCCACCTCTATG
GTCACCCGGCCGACATGGCTGCGGTGATGACGTTCGCTCGCAAACACGGTCTGAAAGTGATCGAGGATTGCGCCCAGGCG
CATGGGGCGGAATTTGACGGAAGGCGCATCGGTGCAATCGGCGATATCGGCGCGTTCAGTTTCTATCCCGGCAAGAATCT
CGGCGCTTATGGCGACGGCGGAGCAATCCTGACCGATGACGAGCAACTTGCGCGCAAATCGCGCATGATTGCCAACCACG
GTCGCATCGACAAGTACGATCATCAGTTCGAAGGGCGCAACAGCCGCCTCGATGGCTTGCAGGCAGCTATCCTGCGGGCG
AAACTGCCTCATCTCGACACGTGGATCGATCGCCGCAACGCTGTTGCACAGCGCTATTTCGATGCGTTGGGAGATCTCGA
TTGGCTGATCCTGCCGACGATTGCCGACAATGTCCGTCACGCGTTTCATCTGTTCGTTGTCAGGACCGATCACCGTGACG
CGTTGCAGGCGTTCCTCAAGGAAAACGGGGTGTCATCCGGCATTCACTATCCGATCGCCCTGCCGGACCTCGGTGCATAC
GACTACCTCCGCGGCCCCGATACACCTATCCTCGCTACGAAGCTCGCGCCGACATTGCTGAGCTTGCCGATGGGAGAGCA
CCTGACTGAAAGCGATACCGACAAGGTTATTGCGGCAGTCCGTTCGTTCCAGCCCTGA

Upstream 100 bases:

>100_bases
TCACGTGGTGATCGGGGCTGGCTCGGTTGTGACGCGCGACATTGTCGAACCGGGAATTTACGCCGGGAACCCGGCACGCA
AGATAAGGGATATTTAACAA

Downstream 100 bases:

>100_bases
GGCGGCAATGAAGATCGTATACCTGCATCAATATTTCGTCACCCCCGAGCAACCCGGGGGGACGCGGTCTTTCGAAATGG
CTCGCAGGTTGGTCGAAGCG

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 365; Mature: 365

Protein sequence:

>365_residues
MVKFLDLVGQYNEIKDEIDVAIARVIGSAAYIGGPDLTAFEEEFADFQQAQHCVGVANGTDALEIAIEALDLPSGSEILV
PANSFVASSEAVTRSGHRVLFCEADAVSYTIDLDDAAHRVTEKTKAMIVVHLYGHPADMAAVMTFARKHGLKVIEDCAQA
HGAEFDGRRIGAIGDIGAFSFYPGKNLGAYGDGGAILTDDEQLARKSRMIANHGRIDKYDHQFEGRNSRLDGLQAAILRA
KLPHLDTWIDRRNAVAQRYFDALGDLDWLILPTIADNVRHAFHLFVVRTDHRDALQAFLKENGVSSGIHYPIALPDLGAY
DYLRGPDTPILATKLAPTLLSLPMGEHLTESDTDKVIAAVRSFQP

Sequences:

>Translated_365_residues
MVKFLDLVGQYNEIKDEIDVAIARVIGSAAYIGGPDLTAFEEEFADFQQAQHCVGVANGTDALEIAIEALDLPSGSEILV
PANSFVASSEAVTRSGHRVLFCEADAVSYTIDLDDAAHRVTEKTKAMIVVHLYGHPADMAAVMTFARKHGLKVIEDCAQA
HGAEFDGRRIGAIGDIGAFSFYPGKNLGAYGDGGAILTDDEQLARKSRMIANHGRIDKYDHQFEGRNSRLDGLQAAILRA
KLPHLDTWIDRRNAVAQRYFDALGDLDWLILPTIADNVRHAFHLFVVRTDHRDALQAFLKENGVSSGIHYPIALPDLGAY
DYLRGPDTPILATKLAPTLLSLPMGEHLTESDTDKVIAAVRSFQP
>Mature_365_residues
MVKFLDLVGQYNEIKDEIDVAIARVIGSAAYIGGPDLTAFEEEFADFQQAQHCVGVANGTDALEIAIEALDLPSGSEILV
PANSFVASSEAVTRSGHRVLFCEADAVSYTIDLDDAAHRVTEKTKAMIVVHLYGHPADMAAVMTFARKHGLKVIEDCAQA
HGAEFDGRRIGAIGDIGAFSFYPGKNLGAYGDGGAILTDDEQLARKSRMIANHGRIDKYDHQFEGRNSRLDGLQAAILRA
KLPHLDTWIDRRNAVAQRYFDALGDLDWLILPTIADNVRHAFHLFVVRTDHRDALQAFLKENGVSSGIHYPIALPDLGAY
DYLRGPDTPILATKLAPTLLSLPMGEHLTESDTDKVIAAVRSFQP

Specific function: Sensor protein that transfers the signal of environmental stimuli to the regulatory region of target genes to activate or repress transcription of erythromycin biosynthesis genes (Potential) [H]

COG id: COG0399

COG function: function code M; Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the degT/dnrJ/eryC1 family [H]

Homologues:

Organism=Escherichia coli, GI145693159, Length=362, Percent_Identity=32.5966850828729, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI2367285, Length=321, Percent_Identity=32.7102803738318, Blast_Score=154, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000653
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01041 DegT_DnrJ_EryC1 [H]

EC number: NA

Molecular weight: Translated: 39820; Mature: 39820

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKFLDLVGQYNEIKDEIDVAIARVIGSAAYIGGPDLTAFEEEFADFQQAQHCVGVANGT
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
DALEIAIEALDLPSGSEILVPANSFVASSEAVTRSGHRVLFCEADAVSYTIDLDDAAHRV
HHHHHEEHHCCCCCCCEEEEECCHHHCCCHHHHCCCCEEEEEECCCEEEEEECCHHHHHH
TEKTKAMIVVHLYGHPADMAAVMTFARKHGLKVIEDCAQAHGAEFDGRRIGAIGDIGAFS
HHHCEEEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEECCEECCCCEE
FYPGKNLGAYGDGGAILTDDEQLARKSRMIANHGRIDKYDHQFEGRNSRLDGLQAAILRA
ECCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KLPHLDTWIDRRNAVAQRYFDALGDLDWLILPTIADNVRHAFHLFVVRTDHRDALQAFLK
HCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHEEEEEEEEEECCHHHHHHHHH
ENGVSSGIHYPIALPDLGAYDYLRGPDTPILATKLAPTLLSLPMGEHLTESDTDKVIAAV
HCCCCCCCCCEEECCCCCCCHHCCCCCCCEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
RSFQP
HHCCC
>Mature Secondary Structure
MVKFLDLVGQYNEIKDEIDVAIARVIGSAAYIGGPDLTAFEEEFADFQQAQHCVGVANGT
CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
DALEIAIEALDLPSGSEILVPANSFVASSEAVTRSGHRVLFCEADAVSYTIDLDDAAHRV
HHHHHEEHHCCCCCCCEEEEECCHHHCCCHHHHCCCCEEEEEECCCEEEEEECCHHHHHH
TEKTKAMIVVHLYGHPADMAAVMTFARKHGLKVIEDCAQAHGAEFDGRRIGAIGDIGAFS
HHHCEEEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCEECCEECCCCEE
FYPGKNLGAYGDGGAILTDDEQLARKSRMIANHGRIDKYDHQFEGRNSRLDGLQAAILRA
ECCCCCCCCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
KLPHLDTWIDRRNAVAQRYFDALGDLDWLILPTIADNVRHAFHLFVVRTDHRDALQAFLK
HCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHEEEEEEEEEECCHHHHHHHHH
ENGVSSGIHYPIALPDLGAYDYLRGPDTPILATKLAPTLLSLPMGEHLTESDTDKVIAAV
HCCCCCCCCCEEECCCCCCCHHCCCCCCCEEHHHHHHHHHHCCCCCCCCCCHHHHHHHHH
RSFQP
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2575703 [H]