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The map label for this gene is pcm [H]

Identifier: 85375409

GI number: 85375409

Start: 2604222

End: 2604821

Strand: Direct

Name: pcm [H]

Synonym: ELI_12910

Alternate gene names: 85375409

Gene position: 2604222-2604821 (Clockwise)

Preceding gene: 85375404

Following gene: 85375410

Centisome position: 85.32

GC content: 66.67

Gene sequence:

>600_bases
ATGATCGATACTGCCACCCGCCCCATCGACTATGCCGCCGCCCGTCGCGCGATGATCGACAGCCAGCTGCGCACCAGCGG
CGTCAATTCGACCGCTGTGCTGGCTCGGATGCTGTCCGTACCGCGCGAGGATCACGTGCCCGCGAGCGCCAGGGGCCATT
GCTACATGGACCGCGCGATCGCGCTCGATAATGGCGGCACGCTGGCACAGCCGGTCTCGCACGGCAAGATGCTGAGCGAA
GCGCGGCCGAACCTCGAAGACAGCGCGCTGATCGTCGAGAACGGCTCGGGCTACCTCGCGGCGCTGGTCGAACCGATGGT
GGCGAAGCTGGACACTGTTTCGGCCGAAGATGCCGCAACGGGCAAGAAGCGCGGCAGCTACAGCCTGATCCTGATCGACG
GCGCGATCGAAGCCTGCCCTGCGGCCCTGGCCAAGCGGCTCGACGAGAACGGTCGCATGGTCACTGGCCTGATCGAAGAC
GGCGTGACCCGCCTCGCGATCGGCAAGCGGCAGGGCAAGGACATGGCATTCCTCCCGGTCGCCGACGTTGCGCTACCGCG
CCTCCCGGCTTTCGATAGCCCGAAAGGCTGGAGCTTCTGA

Upstream 100 bases:

>100_bases
GGCATTCGCAGCCGCATAAGCGCTTGGCCTGTTCGGGCCATATCGGTAAGGGGGAATTGACGAACTGTATTGTCGGTGTA
ATACAGCTACAGGATTTCCC

Downstream 100 bases:

>100_bases
CCATGAAACGTCTCGGGAGGTATCCTGCCCTGCTGTGCGGAGCGTCGCTGCTGGCGGCGAGTCCGGCGCAGGCCGATACC
CTGCGCGAGGCGCTGGTCGA

Product: protein-L-isoaspartate O-methyltransferase

Products: NA

Alternate protein names: L-isoaspartyl protein carboxyl methyltransferase; Protein L-isoaspartyl methyltransferase; Protein-beta-aspartate methyltransferase; PIMT [H]

Number of amino acids: Translated: 199; Mature: 199

Protein sequence:

>199_residues
MIDTATRPIDYAAARRAMIDSQLRTSGVNSTAVLARMLSVPREDHVPASARGHCYMDRAIALDNGGTLAQPVSHGKMLSE
ARPNLEDSALIVENGSGYLAALVEPMVAKLDTVSAEDAATGKKRGSYSLILIDGAIEACPAALAKRLDENGRMVTGLIED
GVTRLAIGKRQGKDMAFLPVADVALPRLPAFDSPKGWSF

Sequences:

>Translated_199_residues
MIDTATRPIDYAAARRAMIDSQLRTSGVNSTAVLARMLSVPREDHVPASARGHCYMDRAIALDNGGTLAQPVSHGKMLSE
ARPNLEDSALIVENGSGYLAALVEPMVAKLDTVSAEDAATGKKRGSYSLILIDGAIEACPAALAKRLDENGRMVTGLIED
GVTRLAIGKRQGKDMAFLPVADVALPRLPAFDSPKGWSF
>Mature_199_residues
MIDTATRPIDYAAARRAMIDSQLRTSGVNSTAVLARMLSVPREDHVPASARGHCYMDRAIALDNGGTLAQPVSHGKMLSE
ARPNLEDSALIVENGSGYLAALVEPMVAKLDTVSAEDAATGKKRGSYSLILIDGAIEACPAALAKRLDENGRMVTGLIED
GVTRLAIGKRQGKDMAFLPVADVALPRLPAFDSPKGWSF

Specific function: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins [H]

COG id: COG2518

COG function: function code O; Protein-L-isoaspartate carboxylmethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: =2.1.1.77 [H]

Molecular weight: Translated: 21103; Mature: 21103

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDTATRPIDYAAARRAMIDSQLRTSGVNSTAVLARMLSVPREDHVPASARGHCYMDRAI
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCEE
ALDNGGTLAQPVSHGKMLSEARPNLEDSALIVENGSGYLAALVEPMVAKLDTVSAEDAAT
EECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHCC
GKKRGSYSLILIDGAIEACPAALAKRLDENGRMVTGLIEDGVTRLAIGKRQGKDMAFLPV
CCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEHHCCHHEEHHCCCCCCCEEEEEH
ADVALPRLPAFDSPKGWSF
HHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MIDTATRPIDYAAARRAMIDSQLRTSGVNSTAVLARMLSVPREDHVPASARGHCYMDRAI
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEECCEE
ALDNGGTLAQPVSHGKMLSEARPNLEDSALIVENGSGYLAALVEPMVAKLDTVSAEDAAT
EECCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCHHCC
GKKRGSYSLILIDGAIEACPAALAKRLDENGRMVTGLIEDGVTRLAIGKRQGKDMAFLPV
CCCCCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEEEHHCCHHEEHHCCCCCCCEEEEEH
ADVALPRLPAFDSPKGWSF
HHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA