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The map label for this gene is ctaA

Identifier: 85375397

GI number: 85375397

Start: 2594668

End: 2595681

Strand: Direct

Name: ctaA

Synonym: ELI_12850

Alternate gene names: 85375397

Gene position: 2594668-2595681 (Clockwise)

Preceding gene: 85375392

Following gene: 85375398

Centisome position: 85.0

GC content: 65.68

Gene sequence:

>1014_bases
ATGGCGCTGGCCCGTTGGCTGTGGGTCGTTGCCGGCCTGGTCGTGACGATCGTCGCAATAGGCGGGATCACCCGGCTGAC
GGAAAGCGGCCTTTCGATCACGCATTGGAGCGTGGTGTCCGGCATCCTCCCGCCGCTGTCCGAAAGCGCCTGGCAGGCCG
AGTTCGACCTTTATCGCCAGACCGGAGAATATCGCCTCGAGAGCGGGCCGGCCGGAATGGACCTGGCCGCTTTCAAGTTC
ATTTATTTCTGGGAATGGTTTCACCGCATCCTGGGGCGGGTGATCGGCCTCGCTTTCCTGCTGCCGATGATGTGGTTCTG
GATCAGGGGCATGATCCCGGCGGGCTACAGGGGGCGGCTGCTCGCCCTCTTCGCGCTGATCTGCGGGCAGGGTGCGCTCG
GCTGGTACATGGTCGCCTCAGGTGTCGGGACCGACCTGACCGATGTCAGCCATTTCCGGCTATCGGCACATTTGTTGACT
GCGCTTTTCCTGCTTGCGGGGCTGGTCTGGACCGCGCTCGACTTGCGGCGACTGGCGCGCGTGCCCGATGCGCGGCCTGC
GCGCTTCACCGGCGTCGCGTGGATGGCTTCGATCATCCTCTTCATCCAGATCCTGCTCGGCGCATGGGTCGCCGGGCTCA
ATGCCGGGCATGCGTCTTACAGCTGGCCGATGATGAATGGCGGGCTCCTGCCGCAGCCCGATCTCACCAGGGGATGGCTG
TGGGCACTGACGCACGATCCCTTCCTGCTGCATTTCCTCCACCGCTGGTGGGCGTGGGTCGCTGTGATTGCGCTCGTCGT
CCTGGCGCGCAAGGTCCGCCCGTTCGACCGCCGTGCGTCGATCGCGGTGCATTCCGCCTTCGGAACCATGGTCGTGCTCG
GCATCGCGACGGTGCTGAGCGAAGTCTCGCTATGGATCGCGGTCGCGCACCAGCTTACCGGCGCGCTGCTGGTGATCTCG
ACCGCTTGGGCGGCGCATGCCATCGGCACGGCGCGCAAGACCGAGGCCGCATGA

Upstream 100 bases:

>100_bases
GCAAACCGCCTTGAAACCTGCACCGCGCGCGACCATTGGAGAGCGCATGGCGACTTTGTCCCAAGTTCCCCCGGTCTCGC
GGAAAGCCCGCGCCGCGCCG

Downstream 100 bases:

>100_bases
GCGCGCTGATCTACGCGCCCTTCCCCGACCGGGAAACCGCCCGGCAGGTCGCCACGCAATTGCTCGACGAAAAGCTGATC
GCCTGCGCCAACCTGCTGGG

Product: cytochrome c oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MALARWLWVVAGLVVTIVAIGGITRLTESGLSITHWSVVSGILPPLSESAWQAEFDLYRQTGEYRLESGPAGMDLAAFKF
IYFWEWFHRILGRVIGLAFLLPMMWFWIRGMIPAGYRGRLLALFALICGQGALGWYMVASGVGTDLTDVSHFRLSAHLLT
ALFLLAGLVWTALDLRRLARVPDARPARFTGVAWMASIILFIQILLGAWVAGLNAGHASYSWPMMNGGLLPQPDLTRGWL
WALTHDPFLLHFLHRWWAWVAVIALVVLARKVRPFDRRASIAVHSAFGTMVVLGIATVLSEVSLWIAVAHQLTGALLVIS
TAWAAHAIGTARKTEAA

Sequences:

>Translated_337_residues
MALARWLWVVAGLVVTIVAIGGITRLTESGLSITHWSVVSGILPPLSESAWQAEFDLYRQTGEYRLESGPAGMDLAAFKF
IYFWEWFHRILGRVIGLAFLLPMMWFWIRGMIPAGYRGRLLALFALICGQGALGWYMVASGVGTDLTDVSHFRLSAHLLT
ALFLLAGLVWTALDLRRLARVPDARPARFTGVAWMASIILFIQILLGAWVAGLNAGHASYSWPMMNGGLLPQPDLTRGWL
WALTHDPFLLHFLHRWWAWVAVIALVVLARKVRPFDRRASIAVHSAFGTMVVLGIATVLSEVSLWIAVAHQLTGALLVIS
TAWAAHAIGTARKTEAA
>Mature_336_residues
ALARWLWVVAGLVVTIVAIGGITRLTESGLSITHWSVVSGILPPLSESAWQAEFDLYRQTGEYRLESGPAGMDLAAFKFI
YFWEWFHRILGRVIGLAFLLPMMWFWIRGMIPAGYRGRLLALFALICGQGALGWYMVASGVGTDLTDVSHFRLSAHLLTA
LFLLAGLVWTALDLRRLARVPDARPARFTGVAWMASIILFIQILLGAWVAGLNAGHASYSWPMMNGGLLPQPDLTRGWLW
ALTHDPFLLHFLHRWWAWVAVIALVVLARKVRPFDRRASIAVHSAFGTMVVLGIATVLSEVSLWIAVAHQLTGALLVIST
AWAAHAIGTARKTEAA

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=334, Percent_Identity=37.7245508982036, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI17921987, Length=291, Percent_Identity=37.8006872852234, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI17536069, Length=341, Percent_Identity=32.8445747800587, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6320989, Length=362, Percent_Identity=33.7016574585635, Blast_Score=173, Evalue=3e-44,
Organism=Drosophila melanogaster, GI19922860, Length=348, Percent_Identity=34.4827586206897, Blast_Score=166, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_ERYLH (Q2N6M9)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_459459.1
- STRING:   Q2N6M9
- GeneID:   3869166
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_12850
- NMPDR:   fig|314225.3.peg.455
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- OMA:   PPMSEAA
- PhylomeDB:   Q2N6M9
- ProtClustDB:   CLSK2775494
- BioCyc:   ELIT314225:ELI_12850-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 37202; Mature: 37071

Theoretical pI: Translated: 10.61; Mature: 10.61

Prosite motif: NA

Important sites: BINDING 310-310

Signals:

None

Transmembrane regions:

HASH(0xce999d4)-; HASH(0xf1f1e58)-; HASH(0xf0a75dc)-; HASH(0xf245b7c)-; HASH(0xf1ba334)-; HASH(0xf1b51f8)-; HASH(0xf1ba310)-; HASH(0xf1b5258)-;

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALARWLWVVAGLVVTIVAIGGITRLTESGLSITHWSVVSGILPPLSESAWQAEFDLYRQ
CHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
TGEYRLESGPAGMDLAAFKFIYFWEWFHRILGRVIGLAFLLPMMWFWIRGMIPAGYRGRL
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LALFALICGQGALGWYMVASGVGTDLTDVSHFRLSAHLLTALFLLAGLVWTALDLRRLAR
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPDARPARFTGVAWMASIILFIQILLGAWVAGLNAGHASYSWPMMNGGLLPQPDLTRGWL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEE
WALTHDPFLLHFLHRWWAWVAVIALVVLARKVRPFDRRASIAVHSAFGTMVVLGIATVLS
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EVSLWIAVAHQLTGALLVISTAWAAHAIGTARKTEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCH
>Mature Secondary Structure 
ALARWLWVVAGLVVTIVAIGGITRLTESGLSITHWSVVSGILPPLSESAWQAEFDLYRQ
HHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHH
TGEYRLESGPAGMDLAAFKFIYFWEWFHRILGRVIGLAFLLPMMWFWIRGMIPAGYRGRL
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
LALFALICGQGALGWYMVASGVGTDLTDVSHFRLSAHLLTALFLLAGLVWTALDLRRLAR
HHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPDARPARFTGVAWMASIILFIQILLGAWVAGLNAGHASYSWPMMNGGLLPQPDLTRGWL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEE
WALTHDPFLLHFLHRWWAWVAVIALVVLARKVRPFDRRASIAVHSAFGTMVVLGIATVLS
EEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
EVSLWIAVAHQLTGALLVISTAWAAHAIGTARKTEAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA