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The map label for this gene is yesM [H]

Identifier: 85375358

GI number: 85375358

Start: 2560303

End: 2561520

Strand: Direct

Name: yesM [H]

Synonym: ELI_12655

Alternate gene names: 85375358

Gene position: 2560303-2561520 (Clockwise)

Preceding gene: 85375356

Following gene: 85375359

Centisome position: 83.88

GC content: 62.15

Gene sequence:

>1218_bases
ATGGCCATGCTGCCCTTTCGCCCTACGCCGTTCTTCGAGAACAAGAACCGCGCGTTCTGGAACCTGCAATTCGCAGGCTG
GACCGGTGCGATCGCGCTGCGTTCGATCCAGGGCATCTCCAACGGCCAGCCGCCATCCTACCTGATCCTGATGCTGATCG
TCGGTATCACCGGTTTTGCCATCAGCACACTGCTGTCCGTGGTCTATCGCCAGCTCATCAATCGCCCGCCCCTGGTGACC
TGGGGCGCGACGGCCGCGGTGCTGGCGATTGCGGTGACGATCTATGCCCTGGTCGAAGCATGGGTGATCAGCCTCTATTT
CGCCGACCGCGATACGACGCTGACGCAGCTGGTGCTGATCTATCTGTTTTTCGATTTCTCGCTGCTCGGTGCGTGGACCG
GTCTCTATTACGCCATCAACTTCTTCCTGCAGGTGGAAGAGCAGGCCGACCGCCTCGAGCGGCTCGAATTGCAGGCGACG
AGCGCGCAGCTCGCCATGCTGCGCTACCAGCTCAACCCGCATTTCCTTTTCAACACGCTCAATTCGATCAGCACGCTCGT
GCTGCTCAAACAGACCGAGCCTGCCAATGCGATGCTGACCCGGCTGTCCGGCTTCCTGCGGCATACGCTGATCACCGAGC
CAGGCGGCAAGGTCACCGTCGCGCAGGAGGTTGAGACGCTGAAGCTTTATCTCGATATCGAGCGCATGCGTTTCGAAGAG
CGGCTGCGGACCGAGTTCGACGTTTCGGACGCAGCCGCCAAGGCGATGCTGCCTTCGCTTCTGCTCCAGCCGCTGGTCGA
GAATGCAATCAAATATGCCGTCTCCCCGCAGGAAGAGGGCGCGCGCATTACGCTGGCGGCGCAATTGGTCGGAGAAAGGC
TGCGCGTCGTCGTTTCCGATACCGGCCCGGGATTGCAAAGGCCCGAAACCCGCGCCAGCCTGCCGCTTGCAATGACGGGC
GCATATACCTCCACGGGTGTGGGGCTCGCCAATATTCGCGACCGGCTTGCCCAGGCCTATGGAGAGGACCACCTGTTCGA
AATCCGCACCCCCGATGATGGCGGGTTCACCGTCATCATCGAAATCCCCCACGAATCCGCATCCAAAGACAGCGGGGAAG
CCGATCCCCCACGGCTCTCCGAACCGGGCGCAGCCGCGACCGACACGCTGCCCGACAATGTGGAATCCCTAGCGGCGCGC
CGCGCCACAGGAAGCTGA

Upstream 100 bases:

>100_bases
CGTTCATGGCAAGGTCTCCTCTTCACAGGCGAAAATAGCGGAATTCCGCGCGATCCGCAAAATATCTGACGTTTGGCCAA
ATTTGTCCTATCTAGGGCGC

Downstream 100 bases:

>100_bases
CCATGACAATCCGAACTATCCTAGTCGACGACGAAAAACTTGCCATCCAGGGCCTGCAATTGCGGCTCGAGCCCTTCGAA
GACGTCGAGATCATCGGCAC

Product: two-component signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MAMLPFRPTPFFENKNRAFWNLQFAGWTGAIALRSIQGISNGQPPSYLILMLIVGITGFAISTLLSVVYRQLINRPPLVT
WGATAAVLAIAVTIYALVEAWVISLYFADRDTTLTQLVLIYLFFDFSLLGAWTGLYYAINFFLQVEEQADRLERLELQAT
SAQLAMLRYQLNPHFLFNTLNSISTLVLLKQTEPANAMLTRLSGFLRHTLITEPGGKVTVAQEVETLKLYLDIERMRFEE
RLRTEFDVSDAAAKAMLPSLLLQPLVENAIKYAVSPQEEGARITLAAQLVGERLRVVVSDTGPGLQRPETRASLPLAMTG
AYTSTGVGLANIRDRLAQAYGEDHLFEIRTPDDGGFTVIIEIPHESASKDSGEADPPRLSEPGAAATDTLPDNVESLAAR
RATGS

Sequences:

>Translated_405_residues
MAMLPFRPTPFFENKNRAFWNLQFAGWTGAIALRSIQGISNGQPPSYLILMLIVGITGFAISTLLSVVYRQLINRPPLVT
WGATAAVLAIAVTIYALVEAWVISLYFADRDTTLTQLVLIYLFFDFSLLGAWTGLYYAINFFLQVEEQADRLERLELQAT
SAQLAMLRYQLNPHFLFNTLNSISTLVLLKQTEPANAMLTRLSGFLRHTLITEPGGKVTVAQEVETLKLYLDIERMRFEE
RLRTEFDVSDAAAKAMLPSLLLQPLVENAIKYAVSPQEEGARITLAAQLVGERLRVVVSDTGPGLQRPETRASLPLAMTG
AYTSTGVGLANIRDRLAQAYGEDHLFEIRTPDDGGFTVIIEIPHESASKDSGEADPPRLSEPGAAATDTLPDNVESLAAR
RATGS
>Mature_404_residues
AMLPFRPTPFFENKNRAFWNLQFAGWTGAIALRSIQGISNGQPPSYLILMLIVGITGFAISTLLSVVYRQLINRPPLVTW
GATAAVLAIAVTIYALVEAWVISLYFADRDTTLTQLVLIYLFFDFSLLGAWTGLYYAINFFLQVEEQADRLERLELQATS
AQLAMLRYQLNPHFLFNTLNSISTLVLLKQTEPANAMLTRLSGFLRHTLITEPGGKVTVAQEVETLKLYLDIERMRFEER
LRTEFDVSDAAAKAMLPSLLLQPLVENAIKYAVSPQEEGARITLAAQLVGERLRVVVSDTGPGLQRPETRASLPLAMTGA
YTSTGVGLANIRDRLAQAYGEDHLFEIRTPDDGGFTVIIEIPHESASKDSGEADPPRLSEPGAAATDTLPDNVESLAARR
ATGS

Specific function: Member of the two-component regulatory system yesM/yesN. Probably activates yesN by phosphorylation [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788446, Length=215, Percent_Identity=32.093023255814, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1788723, Length=195, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR010559
- InterPro:   IPR005467 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 44623; Mature: 44492

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAMLPFRPTPFFENKNRAFWNLQFAGWTGAIALRSIQGISNGQPPSYLILMLIVGITGFA
CCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ISTLLSVVYRQLINRPPLVTWGATAAVLAIAVTIYALVEAWVISLYFADRDTTLTQLVLI
HHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHH
YLFFDFSLLGAWTGLYYAINFFLQVEEQADRLERLELQATSAQLAMLRYQLNPHFLFNTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
NSISTLVLLKQTEPANAMLTRLSGFLRHTLITEPGGKVTVAQEVETLKLYLDIERMRFEE
HHHHEEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCEEEHHHHEEEHHHHHHHHHHHHH
RLRTEFDVSDAAAKAMLPSLLLQPLVENAIKYAVSPQEEGARITLAAQLVGERLRVVVSD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHEEEEEC
TGPGLQRPETRASLPLAMTGAYTSTGVGLANIRDRLAQAYGEDHLFEIRTPDDGGFTVII
CCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEE
EIPHESASKDSGEADPPRLSEPGAAATDTLPDNVESLAARRATGS
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
AMLPFRPTPFFENKNRAFWNLQFAGWTGAIALRSIQGISNGQPPSYLILMLIVGITGFA
CCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
ISTLLSVVYRQLINRPPLVTWGATAAVLAIAVTIYALVEAWVISLYFADRDTTLTQLVLI
HHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHH
YLFFDFSLLGAWTGLYYAINFFLQVEEQADRLERLELQATSAQLAMLRYQLNPHFLFNTL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
NSISTLVLLKQTEPANAMLTRLSGFLRHTLITEPGGKVTVAQEVETLKLYLDIERMRFEE
HHHHEEEEEECCCCHHHHHHHHHHHHHHHHEECCCCCEEEHHHHEEEHHHHHHHHHHHHH
RLRTEFDVSDAAAKAMLPSLLLQPLVENAIKYAVSPQEEGARITLAAQLVGERLRVVVSD
HHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHEEEEEC
TGPGLQRPETRASLPLAMTGAYTSTGVGLANIRDRLAQAYGEDHLFEIRTPDDGGFTVII
CCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCCCCEEEEE
EIPHESASKDSGEADPPRLSEPGAAATDTLPDNVESLAARRATGS
ECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]