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The map label for this gene is uppP

Identifier: 85375240

GI number: 85375240

Start: 2431420

End: 2432277

Strand: Reverse

Name: uppP

Synonym: ELI_12065

Alternate gene names: 85375240

Gene position: 2432277-2431420 (Counterclockwise)

Preceding gene: 85375241

Following gene: 85375239

Centisome position: 79.68

GC content: 60.84

Gene sequence:

>858_bases
ATGACATTCCTGCAGCTCCTCATCATCGCGGTGGTCCAGGGGATCACGGAGTTTCTCCCGATCTCGTCGTCGGGACACCT
GATCCTGATCCCCAATTTTACCGAGTTTCCCGACCAGGGCCCGCTGATCGACGTGGCGGTGCATGTCGGCTCGCTGCTTG
CGATCATCGTCTATTTCTTCAAGGACGTGCTCACGCTCGCGCGCGGCGGCTTTGCGAGCATCGGCATCGGAACCGACCGG
CCCGATGCGCCGAGCGAGCGGCGGCTGTTCTGGTGGATCGTACTGGGGACCATCCCGGCGGTCGCGTTCGGCCTTGCGAT
CAAGCTCGGCGCGTTCAATTCGATTGCGGAGACATGGTTCAATATCACCGTGATCGACGACGACCTGATGAGCTCGATCC
GCTTTACCGATCTCATCGCTTTCAACCTCATCGTCTACGGTATCGCGCTCGGTCTCGCCGACTGGCTCGGCAAGGAAGTG
AAGAAGTTCGAGGATATGAGCTGGCGCGACGGACTGATCGTCGGCATCGCGCAGGCGCTGGCGATCATTCCCGGTACCAG
CCGTTCGGGCGTGACCATGACGGCGGCGCGGGCACTGGGCTATTCGCGCTACGAATCGGCGCGCTTCTCCTTCCTGCTGT
CGATCCCGGCGGTGGCCGGTGCAGGCGTGCTGATCGTGCCCGAAATTTTCGAAGCGGGCGCTACCCTCGCAATGGATGCA
TTGATCGCAGGGGTGCTGACCTTCATTGCGGCCTTCCTCACCATGGCCTTCTTGATGAATTTCCTGAAGCGCGCTTCGAT
GCTTGTGTTCGTCTTCTACCGCGTCGCCATGGGTTGCGCGCTGTTGGCGTTCTTTTGA

Upstream 100 bases:

>100_bases
ATGAAGTCTCGCGCCCCTCCCGCTTGCGGGAGGGGATGGGGGTGGGTAAGGGCGCTGCGTCCGCAATCGCGGTGCATTTG
CAAAGGGTCGGACCTCCGCC

Downstream 100 bases:

>100_bases
CCGTTGCCGGGGCGATTGGTTTCGAATGGAACCAAATACCGGTCCTGCCGTTGCAGGAGTGAGGAGACAGGCAGCGTTTG
ACGAGCAATGGCATTACTTA

Product: undecaprenol kinase, putative

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MTFLQLLIIAVVQGITEFLPISSSGHLILIPNFTEFPDQGPLIDVAVHVGSLLAIIVYFFKDVLTLARGGFASIGIGTDR
PDAPSERRLFWWIVLGTIPAVAFGLAIKLGAFNSIAETWFNITVIDDDLMSSIRFTDLIAFNLIVYGIALGLADWLGKEV
KKFEDMSWRDGLIVGIAQALAIIPGTSRSGVTMTAARALGYSRYESARFSFLLSIPAVAGAGVLIVPEIFEAGATLAMDA
LIAGVLTFIAAFLTMAFLMNFLKRASMLVFVFYRVAMGCALLAFF

Sequences:

>Translated_285_residues
MTFLQLLIIAVVQGITEFLPISSSGHLILIPNFTEFPDQGPLIDVAVHVGSLLAIIVYFFKDVLTLARGGFASIGIGTDR
PDAPSERRLFWWIVLGTIPAVAFGLAIKLGAFNSIAETWFNITVIDDDLMSSIRFTDLIAFNLIVYGIALGLADWLGKEV
KKFEDMSWRDGLIVGIAQALAIIPGTSRSGVTMTAARALGYSRYESARFSFLLSIPAVAGAGVLIVPEIFEAGATLAMDA
LIAGVLTFIAAFLTMAFLMNFLKRASMLVFVFYRVAMGCALLAFF
>Mature_284_residues
TFLQLLIIAVVQGITEFLPISSSGHLILIPNFTEFPDQGPLIDVAVHVGSLLAIIVYFFKDVLTLARGGFASIGIGTDRP
DAPSERRLFWWIVLGTIPAVAFGLAIKLGAFNSIAETWFNITVIDDDLMSSIRFTDLIAFNLIVYGIALGLADWLGKEVK
KFEDMSWRDGLIVGIAQALAIIPGTSRSGVTMTAARALGYSRYESARFSFLLSIPAVAGAGVLIVPEIFEAGATLAMDAL
IAGVLTFIAAFLTMAFLMNFLKRASMLVFVFYRVAMGCALLAFF

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=289, Percent_Identity=31.8339100346021, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_ERYLH (Q2N736)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_459302.1
- ProteinModelPortal:   Q2N736
- STRING:   Q2N736
- GeneID:   3869644
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_12065
- NMPDR:   fig|314225.3.peg.613
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   SAYICVK
- BioCyc:   ELIT314225:ELI_12065-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30834; Mature: 30703

Theoretical pI: Translated: 4.99; Mature: 4.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x43ea05e0)-; HASH(0x43d32328)-; HASH(0x43e2c120)-; HASH(0x43e2bc7c)-; HASH(0xd768c80)-; HASH(0x43e2b634)-; HASH(0x43e1b830)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFLQLLIIAVVQGITEFLPISSSGHLILIPNFTEFPDQGPLIDVAVHVGSLLAIIVYFF
CHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KDVLTLARGGFASIGIGTDRPDAPSERRLFWWIVLGTIPAVAFGLAIKLGAFNSIAETWF
HHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHH
NITVIDDDLMSSIRFTDLIAFNLIVYGIALGLADWLGKEVKKFEDMSWRDGLIVGIAQAL
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AIIPGTSRSGVTMTAARALGYSRYESARFSFLLSIPAVAGAGVLIVPEIFEAGATLAMDA
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECHHHHCCCEEEEHHHHHCCHHHHHHH
LIAGVLTFIAAFLTMAFLMNFLKRASMLVFVFYRVAMGCALLAFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
TFLQLLIIAVVQGITEFLPISSSGHLILIPNFTEFPDQGPLIDVAVHVGSLLAIIVYFF
HHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
KDVLTLARGGFASIGIGTDRPDAPSERRLFWWIVLGTIPAVAFGLAIKLGAFNSIAETWF
HHHHHHHCCCCEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHH
NITVIDDDLMSSIRFTDLIAFNLIVYGIALGLADWLGKEVKKFEDMSWRDGLIVGIAQAL
EEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AIIPGTSRSGVTMTAARALGYSRYESARFSFLLSIPAVAGAGVLIVPEIFEAGATLAMDA
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEECHHHHCCCEEEEHHHHHCCHHHHHHH
LIAGVLTFIAAFLTMAFLMNFLKRASMLVFVFYRVAMGCALLAFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA