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The map label for this gene is pabB [H]

Identifier: 85375215

GI number: 85375215

Start: 2409721

End: 2411532

Strand: Direct

Name: pabB [H]

Synonym: ELI_11940

Alternate gene names: 85375215

Gene position: 2409721-2411532 (Clockwise)

Preceding gene: 85375213

Following gene: 85375216

Centisome position: 78.95

GC content: 66.94

Gene sequence:

>1812_bases
ATGGCCGATCGCGCTCCTTTCGTTTTGCTCGACGATGCCCGTACCGAGGGCGCTGCGCAGGCGCACCTCTACGAGGGTCC
GAGCGAGGTTTTCGTGGCCTATCGACCCGCTGAGGTGGAGAACGCGCTCGCCCGGGCGCAGGCGGCGCAGACGGAACGGG
GCGGGACGCTGGCGGGCTATATCGGCTACGAAGCGGGCTTGGCGCTGGAGCCAAAGTTCATGCCGAGGGCCGATGCCCGC
ACCGGCGCTGGCGGGCCGCTGGTATGGCTCGGCCTGTTCGCGACGGAGCGTGCGGTGGAGGCCGAAGATGTTCCCGGCTG
GCTATCGGAAAACGGGACCGGCCAGGCAACCCTCGGCCCGCTCGATCCGCAAGTCTCGCGCGGGGCTTACGAAGAGGCGT
TTGCCACGCTGCAGGAGGCTATCAAGGCGGGCGATATCTATCAGGCCAATCTGACGCTGCCTTTGGCGGGCGGATATACC
GGCGATCCGGTCGCGCTTTACGCCATGCTGCGACCCGCAGCGAAAGCCGGCTATGGCGGGCTGATCTTCGACGGATCGCA
CTGGCTCTTGAGCCTCAGCCCGGAACTGTTCGTGTCGCTCAAGGACGGGCAAGCTCGAGCCAAGCCGATGAAAGGCACGC
GGCCGCGCGCGGCTGATGCGGAAGCGGACAAGACCTTGGCCGAAGACTTGACGGGTTCGGAGAAAGACAAGGCCGAGAAC
CTGATGATCGTCGATCTGATGCGCAACGACCTGAGCCGCGTGGCCGAGGCGGGCAGCGTGACGGTGGAAAAGCCTTTCGC
GGTCGAGAGCTACCCGACCGTGCACCAGATGGTCACGACGGTCCACGCGCGGCTGCAACCCGGAAAGGGCGCGATGGACC
TGATCCACGCGCTGTTCCCCTGCGGCTCGATTACAGGCGCGCCCAAGATCCGCGCAATGGAACTGATTGACCGTGTCGAG
CCCGATGCGCGCGGCCCCTATTGCGGCGCGATCGGGCGGATCGATGGCGATGGCAACGCCGCCTTCAACGTCGCCATCCG
GACATTGCGCCTCACGCCGATAGAGAACGAGCGCGGCAAGGCGGTGCTCGGCGTCGGCTCGGCCATCGTGGCGGACAGCG
ATTGCGGCACCGAATGGCGCGAGACAATCCTCAAGGGCGGCTTCGCACGCGCCAGCGATGCGCAGGCCCAGGCGCCCGGC
TTCCACCTGATCGAAACGATGCGCTTCGATCCGGAGCGTGGGATCGAATTGCTCGAACTGCACCTCGAGCGGATGAAGGC
GAGCGCGGCGGAGCTGGGCTTCACCTTCGATCGGCACGCCACCCGCAACCAGATCCAGGCGCTGTGCTTCGATCTGGAGC
AGCCTGCACGCGTGCGGCTGACCAGCGGTCGGACTGGTAATATCGCGCTCGAGGCAACCCCGCTCGGCGCGCCCTGGAGC
GAGCCGGCGAGATGCGCGATCCTGCCGCTGCCGGTCGATCCCGGCGACTGGCGCTTGCGCCACAAGACCAGCGATCGGGG
CTTTTACGAGGCAGCGCAGCATGTGGCACGCGAGGCCCAAGCGCAGGAGGCACTGTTGCTGCACCCCGATGGTCAGCTGA
CCGAAGGCTGCATCTCCAACATCTTCGTCGAGCGCGAGGGGCGGCTTGTGACACCGCCCGCTGCGCTGGGCCTGCTGCCG
GGCGTGTTGCGGCGCTCGCTGATCGAACAGGGCCGCGCGGTCGAAGGGGAAGTCCGCATCGAAGACCTCGAAGGCGGTTT
CTTCATCGGCAACGCCGTGCGCGGGCTGGTGAAGGCCGAGCTCATCGCCTAG

Upstream 100 bases:

>100_bases
TTGTACCCCCAATCCGGTGTGGTTGTGACGATGTGGCGGCAGGAGCAGCTATCGGTCAAGTGAGGTTCCAATTCCCGCAT
CACGCTTTATGGCGGAGGGA

Downstream 100 bases:

>100_bases
AAACCCTTCGGGCTGAGGCTGTCGAAGCCCTGCATTTTCTTTTAGCGCTGCTCTCAAAGTGAAGGACAGCCCTTCGACAG
GTTCAGGGCGAACGAACAAT

Product: Para-aminobenzoate synthase, component I

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 603; Mature: 602

Protein sequence:

>603_residues
MADRAPFVLLDDARTEGAAQAHLYEGPSEVFVAYRPAEVENALARAQAAQTERGGTLAGYIGYEAGLALEPKFMPRADAR
TGAGGPLVWLGLFATERAVEAEDVPGWLSENGTGQATLGPLDPQVSRGAYEEAFATLQEAIKAGDIYQANLTLPLAGGYT
GDPVALYAMLRPAAKAGYGGLIFDGSHWLLSLSPELFVSLKDGQARAKPMKGTRPRAADAEADKTLAEDLTGSEKDKAEN
LMIVDLMRNDLSRVAEAGSVTVEKPFAVESYPTVHQMVTTVHARLQPGKGAMDLIHALFPCGSITGAPKIRAMELIDRVE
PDARGPYCGAIGRIDGDGNAAFNVAIRTLRLTPIENERGKAVLGVGSAIVADSDCGTEWRETILKGGFARASDAQAQAPG
FHLIETMRFDPERGIELLELHLERMKASAAELGFTFDRHATRNQIQALCFDLEQPARVRLTSGRTGNIALEATPLGAPWS
EPARCAILPLPVDPGDWRLRHKTSDRGFYEAAQHVAREAQAQEALLLHPDGQLTEGCISNIFVEREGRLVTPPAALGLLP
GVLRRSLIEQGRAVEGEVRIEDLEGGFFIGNAVRGLVKAELIA

Sequences:

>Translated_603_residues
MADRAPFVLLDDARTEGAAQAHLYEGPSEVFVAYRPAEVENALARAQAAQTERGGTLAGYIGYEAGLALEPKFMPRADAR
TGAGGPLVWLGLFATERAVEAEDVPGWLSENGTGQATLGPLDPQVSRGAYEEAFATLQEAIKAGDIYQANLTLPLAGGYT
GDPVALYAMLRPAAKAGYGGLIFDGSHWLLSLSPELFVSLKDGQARAKPMKGTRPRAADAEADKTLAEDLTGSEKDKAEN
LMIVDLMRNDLSRVAEAGSVTVEKPFAVESYPTVHQMVTTVHARLQPGKGAMDLIHALFPCGSITGAPKIRAMELIDRVE
PDARGPYCGAIGRIDGDGNAAFNVAIRTLRLTPIENERGKAVLGVGSAIVADSDCGTEWRETILKGGFARASDAQAQAPG
FHLIETMRFDPERGIELLELHLERMKASAAELGFTFDRHATRNQIQALCFDLEQPARVRLTSGRTGNIALEATPLGAPWS
EPARCAILPLPVDPGDWRLRHKTSDRGFYEAAQHVAREAQAQEALLLHPDGQLTEGCISNIFVEREGRLVTPPAALGLLP
GVLRRSLIEQGRAVEGEVRIEDLEGGFFIGNAVRGLVKAELIA
>Mature_602_residues
ADRAPFVLLDDARTEGAAQAHLYEGPSEVFVAYRPAEVENALARAQAAQTERGGTLAGYIGYEAGLALEPKFMPRADART
GAGGPLVWLGLFATERAVEAEDVPGWLSENGTGQATLGPLDPQVSRGAYEEAFATLQEAIKAGDIYQANLTLPLAGGYTG
DPVALYAMLRPAAKAGYGGLIFDGSHWLLSLSPELFVSLKDGQARAKPMKGTRPRAADAEADKTLAEDLTGSEKDKAENL
MIVDLMRNDLSRVAEAGSVTVEKPFAVESYPTVHQMVTTVHARLQPGKGAMDLIHALFPCGSITGAPKIRAMELIDRVEP
DARGPYCGAIGRIDGDGNAAFNVAIRTLRLTPIENERGKAVLGVGSAIVADSDCGTEWRETILKGGFARASDAQAQAPGF
HLIETMRFDPERGIELLELHLERMKASAAELGFTFDRHATRNQIQALCFDLEQPARVRLTSGRTGNIALEATPLGAPWSE
PARCAILPLPVDPGDWRLRHKTSDRGFYEAAQHVAREAQAQEALLLHPDGQLTEGCISNIFVEREGRLVTPPAALGLLPG
VLRRSLIEQGRAVEGEVRIEDLEGGFFIGNAVRGLVKAELIA

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=261, Percent_Identity=44.0613026819923, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1787518, Length=258, Percent_Identity=32.1705426356589, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786809, Length=198, Percent_Identity=28.7878787878788, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320935, Length=280, Percent_Identity=35, Blast_Score=154, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6324361, Length=249, Percent_Identity=28.1124497991968, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 64635; Mature: 64504

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00770 AA_TRANSFER_CLASS_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADRAPFVLLDDARTEGAAQAHLYEGPSEVFVAYRPAEVENALARAQAAQTERGGTLAGY
CCCCCCEEEEECCCCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEE
IGYEAGLALEPKFMPRADARTGAGGPLVWLGLFATERAVEAEDVPGWLSENGTGQATLGP
ECCCCCCEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHCCCCCCCCHHCCCCCCCEEECC
LDPQVSRGAYEEAFATLQEAIKAGDIYQANLTLPLAGGYTGDPVALYAMLRPAAKAGYGG
CCCHHHCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
LIFDGSHWLLSLSPELFVSLKDGQARAKPMKGTRPRAADAEADKTLAEDLTGSEKDKAEN
EEEECCCEEEEECHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCC
LMIVDLMRNDLSRVAEAGSVTVEKPFAVESYPTVHQMVTTVHARLQPGKGAMDLIHALFP
EEEEHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHC
CGSITGAPKIRAMELIDRVEPDARGPYCGAIGRIDGDGNAAFNVAIRTLRLTPIENERGK
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCEEEEEEEEEEEECCCCCCCC
AVLGVGSAIVADSDCGTEWRETILKGGFARASDAQAQAPGFHLIETMRFDPERGIELLEL
EEEECCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHCHHHHHH
HLERMKASAAELGFTFDRHATRNQIQALCFDLEQPARVRLTSGRTGNIALEATPLGAPWS
HHHHHHHHHHHHCCEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCC
EPARCAILPLPVDPGDWRLRHKTSDRGFYEAAQHVAREAQAQEALLLHPDGQLTEGCISN
CCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHH
IFVEREGRLVTPPAALGLLPGVLRRSLIEQGRAVEGEVRIEDLEGGFFIGNAVRGLVKAE
EEEECCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHHH
LIA
HCC
>Mature Secondary Structure 
ADRAPFVLLDDARTEGAAQAHLYEGPSEVFVAYRPAEVENALARAQAAQTERGGTLAGY
CCCCCEEEEECCCCCCCCCEEEECCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEE
IGYEAGLALEPKFMPRADARTGAGGPLVWLGLFATERAVEAEDVPGWLSENGTGQATLGP
ECCCCCCEECCCCCCCCCCCCCCCCCEEEEEHHHHHHHCCCCCCCCHHCCCCCCCEEECC
LDPQVSRGAYEEAFATLQEAIKAGDIYQANLTLPLAGGYTGDPVALYAMLRPAAKAGYGG
CCCHHHCCHHHHHHHHHHHHHHCCCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCC
LIFDGSHWLLSLSPELFVSLKDGQARAKPMKGTRPRAADAEADKTLAEDLTGSEKDKAEN
EEEECCCEEEEECHHHEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHCC
LMIVDLMRNDLSRVAEAGSVTVEKPFAVESYPTVHQMVTTVHARLQPGKGAMDLIHALFP
EEEEHHHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHC
CGSITGAPKIRAMELIDRVEPDARGPYCGAIGRIDGDGNAAFNVAIRTLRLTPIENERGK
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCEEEEEEEEEEEECCCCCCCC
AVLGVGSAIVADSDCGTEWRETILKGGFARASDAQAQAPGFHLIETMRFDPERGIELLEL
EEEECCCEEEECCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHCCCHHHCHHHHHH
HLERMKASAAELGFTFDRHATRNQIQALCFDLEQPARVRLTSGRTGNIALEATPLGAPWS
HHHHHHHHHHHHCCEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEEEECCCCCCC
EPARCAILPLPVDPGDWRLRHKTSDRGFYEAAQHVAREAQAQEALLLHPDGQLTEGCISN
CCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHHH
IFVEREGRLVTPPAALGLLPGVLRRSLIEQGRAVEGEVRIEDLEGGFFIGNAVRGLVKAE
EEEECCCCEECCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEHHHHHHHHHHH
LIA
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 2251281 [H]