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The map label for this gene is mmgC [H]

Identifier: 85375042

GI number: 85375042

Start: 2237254

End: 2238417

Strand: Reverse

Name: mmgC [H]

Synonym: ELI_11075

Alternate gene names: 85375042

Gene position: 2238417-2237254 (Counterclockwise)

Preceding gene: 85375045

Following gene: 85375041

Centisome position: 73.33

GC content: 61.0

Gene sequence:

>1164_bases
ATGCCCGCCATCGACGTACCCCAGCCCGAATTCATGGAAGACGAAGAGATTTCGATCTTCGCCGATGCCGTCGGCAAGTT
CTACCAGCAGCATGCGCCGGAGAAGCGCGTCAAGAAATGGCGCGAAGAGGGGCAGGTCGAGCGCGAGTTCTGGAACGAGG
CGGGCGCGGCAGGCTTGCTCGGCGTTTCCGTGCCCGAAGAATATGGCGGCCACGGCGGCGATTTCCGTCATGACATGGTG
GTGATCGACCAGCAGGCCAAGCACGGCGTCGATGGCTTCGCCGCCAGCCTGCACAACACCATCATCCTGCCCTACCTCGT
GCGTCACGGCACCGAGGAGCAGAAGAAGAAATACCTGCCCAAGCTTGTGACCGGCGAGCTCGTCAGCGCAATCGCCATGA
CCGAGCCGGGTGTCGGCAGCGATTTGCAGAGCATCACCACGACCGCGCTCAAGGACGGCAACGGTTACCGCATCAACGGG
GCCAAGACCTATATCTCCAACGGCCAGACGGCGGACTTCATCGTTGTCGTCGCCAAGACCGACCCGAACGAGCGCGCCAA
GGGCATCTCGCTGATGCTGCTGGAAACCGAAGGCGCGGAAGGCTTCCAGCGCGGCAAGAAGCTCGACAAGATCGGGCTGG
ACGCTGCCGATACGTCGGAGCTGTTCTTCGACAATGTCTTCGTTCCGGCTGAAAACGTGCTCGGCGGGGTCGAAGGCAAG
GGTTTCTATCAGCTGATGGGCGAACTGGCGCAGGAGCGGCTGGTGATCGCGATGGGCGCGGCCACCGGCATTGAGAAAGC
GCTCGAAGTGACGCTCGAATACGTCAAAGAACGCAAGGCCTTCGGGCAGACGATCTGGGATTTCCAGAACACCCAGTTCG
TGCTTGCCGACCTCAAGGCGCGCGGCACGGCGGCGCGCGTGTTCGTGAACGATTGCATCGCCAAGCTGCTGAAGGGCGAA
CTCGACGTGGCAACAGCGGCCATGGCGAAATACTGGGTCACCGAATTGCAGAGCGAAGTGGTCGACAAGTGTCTCCAGCT
CCACGGCGGCGCGGGCTATATCAACGAATATCCCATCGCCAAGATGTACCGCGATGCCCGCATCACACGGATTTTCGGTG
GTTCGAACGAAGTCATGAAGATGCTGATCGCGCGTTCGATGTAG

Upstream 100 bases:

>100_bases
CCATGCGCCGCGTGTTTTACGGCCTTTGGAATGCGTTGCGGTCCGCTACCGACATGATACGGTGCGACGCAACATCTAAA
TACTGGAGAGGACCACACCC

Downstream 100 bases:

>100_bases
CTGGAGGGGAGGAAACTATCGCGCCCGCAGCCGTTGGTTTGGCGAAGGAGTGGCGCGATAGCGGAAGAGCCGCAAAATTT
AGAAGACGTTCTCGGCGACA

Product: acyl-CoA dehydrogenase, long-chain specific

Products: 2,3-dehydroacyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MPAIDVPQPEFMEDEEISIFADAVGKFYQQHAPEKRVKKWREEGQVEREFWNEAGAAGLLGVSVPEEYGGHGGDFRHDMV
VIDQQAKHGVDGFAASLHNTIILPYLVRHGTEEQKKKYLPKLVTGELVSAIAMTEPGVGSDLQSITTTALKDGNGYRING
AKTYISNGQTADFIVVVAKTDPNERAKGISLMLLETEGAEGFQRGKKLDKIGLDAADTSELFFDNVFVPAENVLGGVEGK
GFYQLMGELAQERLVIAMGAATGIEKALEVTLEYVKERKAFGQTIWDFQNTQFVLADLKARGTAARVFVNDCIAKLLKGE
LDVATAAMAKYWVTELQSEVVDKCLQLHGGAGYINEYPIAKMYRDARITRIFGGSNEVMKMLIARSM

Sequences:

>Translated_387_residues
MPAIDVPQPEFMEDEEISIFADAVGKFYQQHAPEKRVKKWREEGQVEREFWNEAGAAGLLGVSVPEEYGGHGGDFRHDMV
VIDQQAKHGVDGFAASLHNTIILPYLVRHGTEEQKKKYLPKLVTGELVSAIAMTEPGVGSDLQSITTTALKDGNGYRING
AKTYISNGQTADFIVVVAKTDPNERAKGISLMLLETEGAEGFQRGKKLDKIGLDAADTSELFFDNVFVPAENVLGGVEGK
GFYQLMGELAQERLVIAMGAATGIEKALEVTLEYVKERKAFGQTIWDFQNTQFVLADLKARGTAARVFVNDCIAKLLKGE
LDVATAAMAKYWVTELQSEVVDKCLQLHGGAGYINEYPIAKMYRDARITRIFGGSNEVMKMLIARSM
>Mature_386_residues
PAIDVPQPEFMEDEEISIFADAVGKFYQQHAPEKRVKKWREEGQVEREFWNEAGAAGLLGVSVPEEYGGHGGDFRHDMVV
IDQQAKHGVDGFAASLHNTIILPYLVRHGTEEQKKKYLPKLVTGELVSAIAMTEPGVGSDLQSITTTALKDGNGYRINGA
KTYISNGQTADFIVVVAKTDPNERAKGISLMLLETEGAEGFQRGKKLDKIGLDAADTSELFFDNVFVPAENVLGGVEGKG
FYQLMGELAQERLVIAMGAATGIEKALEVTLEYVKERKAFGQTIWDFQNTQFVLADLKARGTAARVFVNDCIAKLLKGEL
DVATAAMAKYWVTELQSEVVDKCLQLHGGAGYINEYPIAKMYRDARITRIFGGSNEVMKMLIARSM

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501857, Length=374, Percent_Identity=48.1283422459893, Blast_Score=344, Evalue=6e-95,
Organism=Homo sapiens, GI226958412, Length=379, Percent_Identity=38.2585751978892, Blast_Score=249, Evalue=4e-66,
Organism=Homo sapiens, GI226958414, Length=345, Percent_Identity=39.1304347826087, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI4501859, Length=381, Percent_Identity=36.4829396325459, Blast_Score=216, Evalue=2e-56,
Organism=Homo sapiens, GI21361497, Length=395, Percent_Identity=34.6835443037975, Blast_Score=193, Evalue=2e-49,
Organism=Homo sapiens, GI187960098, Length=334, Percent_Identity=32.9341317365269, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI4557231, Length=334, Percent_Identity=32.9341317365269, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI7656849, Length=363, Percent_Identity=33.6088154269972, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI4557233, Length=333, Percent_Identity=33.9339339339339, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI76496475, Length=396, Percent_Identity=31.8181818181818, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI4557235, Length=396, Percent_Identity=31.8181818181818, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI4503943, Length=399, Percent_Identity=26.5664160401003, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI211971008, Length=294, Percent_Identity=32.9931972789116, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI48976061, Length=294, Percent_Identity=32.9931972789116, Blast_Score=109, Evalue=4e-24,
Organism=Homo sapiens, GI7669494, Length=307, Percent_Identity=29.9674267100977, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI38505218, Length=380, Percent_Identity=27.3684210526316, Blast_Score=101, Evalue=1e-21,
Organism=Escherichia coli, GI87081958, Length=379, Percent_Identity=29.5514511873351, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1786223, Length=336, Percent_Identity=28.2738095238095, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI87081702, Length=409, Percent_Identity=23.2273838630807, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI87082384, Length=272, Percent_Identity=25, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538396, Length=379, Percent_Identity=36.4116094986807, Blast_Score=243, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17508101, Length=385, Percent_Identity=34.2857142857143, Blast_Score=206, Evalue=2e-53,
Organism=Caenorhabditis elegans, GI17506239, Length=384, Percent_Identity=34.1145833333333, Blast_Score=202, Evalue=2e-52,
Organism=Caenorhabditis elegans, GI17551932, Length=354, Percent_Identity=34.180790960452, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI17505929, Length=385, Percent_Identity=31.9480519480519, Blast_Score=194, Evalue=8e-50,
Organism=Caenorhabditis elegans, GI17533517, Length=355, Percent_Identity=32.9577464788732, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17534899, Length=353, Percent_Identity=31.728045325779, Blast_Score=190, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17570075, Length=343, Percent_Identity=33.2361516034985, Blast_Score=187, Evalue=7e-48,
Organism=Caenorhabditis elegans, GI17569725, Length=354, Percent_Identity=31.9209039548023, Blast_Score=183, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI71990804, Length=287, Percent_Identity=38.6759581881533, Blast_Score=174, Evalue=9e-44,
Organism=Caenorhabditis elegans, GI71985184, Length=394, Percent_Identity=30.9644670050761, Blast_Score=169, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI32563615, Length=231, Percent_Identity=37.6623376623377, Blast_Score=150, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI71985192, Length=345, Percent_Identity=30.1449275362319, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71982178, Length=266, Percent_Identity=28.9473684210526, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17534353, Length=384, Percent_Identity=26.8229166666667, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17562446, Length=293, Percent_Identity=30.7167235494881, Blast_Score=101, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17531909, Length=241, Percent_Identity=27.8008298755187, Blast_Score=96, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17552648, Length=364, Percent_Identity=24.7252747252747, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI86563381, Length=279, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI86563383, Length=279, Percent_Identity=25.8064516129032, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355753, Length=384, Percent_Identity=34.8958333333333, Blast_Score=217, Evalue=8e-57,
Organism=Drosophila melanogaster, GI24666513, Length=389, Percent_Identity=33.6760925449871, Blast_Score=204, Evalue=6e-53,
Organism=Drosophila melanogaster, GI21356377, Length=367, Percent_Identity=34.3324250681199, Blast_Score=192, Evalue=3e-49,
Organism=Drosophila melanogaster, GI24660351, Length=335, Percent_Identity=33.4328358208955, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI24646207, Length=334, Percent_Identity=34.7305389221557, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI281363737, Length=340, Percent_Identity=32.6470588235294, Blast_Score=159, Evalue=4e-39,
Organism=Drosophila melanogaster, GI19920834, Length=294, Percent_Identity=30.6122448979592, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.3

Molecular weight: Translated: 42552; Mature: 42421

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAIDVPQPEFMEDEEISIFADAVGKFYQQHAPEKRVKKWREEGQVEREFWNEAGAAGLL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCCCEE
GVSVPEEYGGHGGDFRHDMVVIDQQAKHGVDGFAASLHNTIILPYLVRHGTEEQKKKYLP
ECCCCHHHCCCCCCCCCCEEEEECHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCH
KLVTGELVSAIAMTEPGVGSDLQSITTTALKDGNGYRINGAKTYISNGQTADFIVVVAKT
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEECCCEEEECCCCCCEEEEEEEEC
DPNERAKGISLMLLETEGAEGFQRGKKLDKIGLDAADTSELFFDNVFVPAENVLGGVEGK
CCCCHHCCEEEEEEECCCCHHHHHCCHHHHHCCCCCCCHHHHHCCCCCCHHHHHCCCCCC
GFYQLMGELAQERLVIAMGAATGIEKALEVTLEYVKERKAFGQTIWDFQNTQFVLADLKA
HHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHC
RGTAARVFVNDCIAKLLKGELDVATAAMAKYWVTELQSEVVDKCLQLHGGAGYINEYPIA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
KMYRDARITRIFGGSNEVMKMLIARSM
HHHHHHHEEEEECCCHHHHHHHHHHCC
>Mature Secondary Structure 
PAIDVPQPEFMEDEEISIFADAVGKFYQQHAPEKRVKKWREEGQVEREFWNEAGAAGLL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHCCCCCEE
GVSVPEEYGGHGGDFRHDMVVIDQQAKHGVDGFAASLHNTIILPYLVRHGTEEQKKKYLP
ECCCCHHHCCCCCCCCCCEEEEECHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCH
KLVTGELVSAIAMTEPGVGSDLQSITTTALKDGNGYRINGAKTYISNGQTADFIVVVAKT
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEECCCEEEECCCCCCEEEEEEEEC
DPNERAKGISLMLLETEGAEGFQRGKKLDKIGLDAADTSELFFDNVFVPAENVLGGVEGK
CCCCHHCCEEEEEEECCCCHHHHHCCHHHHHCCCCCCCHHHHHCCCCCCHHHHHCCCCCC
GFYQLMGELAQERLVIAMGAATGIEKALEVTLEYVKERKAFGQTIWDFQNTQFVLADLKA
HHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHHC
RGTAARVFVNDCIAKLLKGELDVATAAMAKYWVTELQSEVVDKCLQLHGGAGYINEYPIA
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHH
KMYRDARITRIFGGSNEVMKMLIARSM
HHHHHHHEEEEECCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; acceptor

Specific reaction: acyl-CoA + acceptor = 2,3-dehydroacyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]