Click here to switch to the map view.

The map label for this gene is cysS [H]

Identifier: 85374564

GI number: 85374564

Start: 1769013

End: 1770515

Strand: Reverse

Name: cysS [H]

Synonym: ELI_08685

Alternate gene names: 85374564

Gene position: 1770515-1769013 (Counterclockwise)

Preceding gene: 85374565

Following gene: 85374563

Centisome position: 58.0

GC content: 61.61

Gene sequence:

>1503_bases
ATGACCACCACGCCGCTCAAGCTGTTCAATTCGCTCACCCGCTCGCTGGAGGAATTCCAGCCGATCCACCCGGGCGAAGC
GCGCGTCTATACCTGCGGGCCGACGGTCTATAACTACCAGCATATCGGAAATATGCGGGCCTATATCTTCGCCGATACGC
TGGGGCGTACGCTCAGCTGGAAGGGCTTCGACCTCAAGCATGTGATCAACATCACCGATGTCGGCCACCTGACCTCGGAT
GCCGATGCGGGCGACGACAAGATGGAAAAGGCCGCCGCGCGCGAGGGCAAGAGCGCATGGGACATCGCGCGCTACTACCA
GCAAGTGTTCGAGGCCGACCTGGATCGGCTCAACATTCGCAAGCCCGAGCACCCGCGTGCGACAGACTATGTCGAAAGCA
TGATCGCATGGGCCAAAAGCATCGAAGCGAAGCATTGCTACGAGCTCGACAGCGGGCTCTATTTCGATGTCTCGACCGTA
CCCGAATACGGGCGGCTGGCGCGCGCCGTAACCGATGAAGGTGAAGGCCGCATCGATGAGGTCGAAGGCAAGCGCAACGC
CGCCGACTTCGCGATCTGGCGCAAGACCCCGCCGGGCGAGACGCGGCAGATGGAATGGGATTCGCCGTGGGGCAAGGGCG
CACCGGGGTGGCACCTCGAATGCTCGGTCATGAGCGCAGAACTGCTCGGCCACCCGTTCGACATCCACACCGGCGGAATC
GATCACCGCGAGATCCACCACCCCAACGAGATCGCGCAGAACCAGGCGCATAATTGCTCGCCCGACAGCGGCGCGAAGAT
CTGGATGCACAACAACTTCCTGATCGACCGGCGCGGGAAGATGTCGAAAAGCTCGGGCGAGTTCCTGACGCTGCAGGCGC
TGGTCGACCGCGGCTTCCACCCGCTCGCCTACCGCATGCTGTGCCTGCAGGCGCATTATCGCAGCGAGCTGGAATTCACG
TGGGAAGGATTGGAAGCGGCGCTGGTGCGGTTAAAGCGCATGGTAATGGCGCTCGAAACCCTCAAGGCCCGTCATGCTGA
ACTCGTTTCAGCATCGATGCCGAACTCCAAACCGTGGGCGCAAATGGAAGCATGGACCCTGAAACAAGTTCAGGGTGACG
ATTGGGGGAAGCTTGGCCCTGCAATCGAGAAGTTCGGCACCGCAATCGCCGATGATCTCAATACCGCAATCTCCCTGACC
GCCATGGAAGACCTTCTCGCCACCAAGAAGATCGATCCTGCTAAGAAGCTCGTTCTCGCAAGTGCTTTCGATGCCGTTTT
GGGTTTTGACCTCCTCAACCTTTCTCGCACCGATCTCCGCACCCGCCCCGCGACCGCCGAAATCAGCGAAGCCGAAATCG
AGGCCGCGTTCGCCGAGCGCAAGGAAGCCCGCGCGGCCAAGGACTTCGCCCGCTCCGACGCAATCCGCGACGACCTCGCG
GCCAAAGGCGTCGAGGTTATGGACGGCGACCCGCTCGGCTGGGAGTGGAAGCGGGGCACTTGA

Upstream 100 bases:

>100_bases
CCGTCATCCCAGCGCAAGCTGGGATCTCTCTCAATCCCGTCGCGCCGGTGGAGCCAGATCCCAGCTTGCGCTGGGATGAC
GGGCATATATTAGGCCCCAC

Downstream 100 bases:

>100_bases
CCAATCCTAATTCTCAAACCCCGTTCGCCCTGAGCCGGTGGCGCTTTGCGCCGTCTTTGACTCCGAAGGGCAGCCACGGC
TGTTGCGGCTGGGCTTCGAC

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 500; Mature: 499

Protein sequence:

>500_residues
MTTTPLKLFNSLTRSLEEFQPIHPGEARVYTCGPTVYNYQHIGNMRAYIFADTLGRTLSWKGFDLKHVINITDVGHLTSD
ADAGDDKMEKAAAREGKSAWDIARYYQQVFEADLDRLNIRKPEHPRATDYVESMIAWAKSIEAKHCYELDSGLYFDVSTV
PEYGRLARAVTDEGEGRIDEVEGKRNAADFAIWRKTPPGETRQMEWDSPWGKGAPGWHLECSVMSAELLGHPFDIHTGGI
DHREIHHPNEIAQNQAHNCSPDSGAKIWMHNNFLIDRRGKMSKSSGEFLTLQALVDRGFHPLAYRMLCLQAHYRSELEFT
WEGLEAALVRLKRMVMALETLKARHAELVSASMPNSKPWAQMEAWTLKQVQGDDWGKLGPAIEKFGTAIADDLNTAISLT
AMEDLLATKKIDPAKKLVLASAFDAVLGFDLLNLSRTDLRTRPATAEISEAEIEAAFAERKEARAAKDFARSDAIRDDLA
AKGVEVMDGDPLGWEWKRGT

Sequences:

>Translated_500_residues
MTTTPLKLFNSLTRSLEEFQPIHPGEARVYTCGPTVYNYQHIGNMRAYIFADTLGRTLSWKGFDLKHVINITDVGHLTSD
ADAGDDKMEKAAAREGKSAWDIARYYQQVFEADLDRLNIRKPEHPRATDYVESMIAWAKSIEAKHCYELDSGLYFDVSTV
PEYGRLARAVTDEGEGRIDEVEGKRNAADFAIWRKTPPGETRQMEWDSPWGKGAPGWHLECSVMSAELLGHPFDIHTGGI
DHREIHHPNEIAQNQAHNCSPDSGAKIWMHNNFLIDRRGKMSKSSGEFLTLQALVDRGFHPLAYRMLCLQAHYRSELEFT
WEGLEAALVRLKRMVMALETLKARHAELVSASMPNSKPWAQMEAWTLKQVQGDDWGKLGPAIEKFGTAIADDLNTAISLT
AMEDLLATKKIDPAKKLVLASAFDAVLGFDLLNLSRTDLRTRPATAEISEAEIEAAFAERKEARAAKDFARSDAIRDDLA
AKGVEVMDGDPLGWEWKRGT
>Mature_499_residues
TTTPLKLFNSLTRSLEEFQPIHPGEARVYTCGPTVYNYQHIGNMRAYIFADTLGRTLSWKGFDLKHVINITDVGHLTSDA
DAGDDKMEKAAAREGKSAWDIARYYQQVFEADLDRLNIRKPEHPRATDYVESMIAWAKSIEAKHCYELDSGLYFDVSTVP
EYGRLARAVTDEGEGRIDEVEGKRNAADFAIWRKTPPGETRQMEWDSPWGKGAPGWHLECSVMSAELLGHPFDIHTGGID
HREIHHPNEIAQNQAHNCSPDSGAKIWMHNNFLIDRRGKMSKSSGEFLTLQALVDRGFHPLAYRMLCLQAHYRSELEFTW
EGLEAALVRLKRMVMALETLKARHAELVSASMPNSKPWAQMEAWTLKQVQGDDWGKLGPAIEKFGTAIADDLNTAISLTA
MEDLLATKKIDPAKKLVLASAFDAVLGFDLLNLSRTDLRTRPATAEISEAEIEAAFAERKEARAAKDFARSDAIRDDLAA
KGVEVMDGDPLGWEWKRGT

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=327, Percent_Identity=33.9449541284404, Blast_Score=169, Evalue=8e-42,
Organism=Homo sapiens, GI10835051, Length=245, Percent_Identity=33.8775510204082, Blast_Score=127, Evalue=4e-29,
Organism=Homo sapiens, GI21269877, Length=245, Percent_Identity=33.8775510204082, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI62240992, Length=245, Percent_Identity=33.8775510204082, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI303304987, Length=245, Percent_Identity=33.8775510204082, Blast_Score=126, Evalue=5e-29,
Organism=Escherichia coli, GI1786737, Length=508, Percent_Identity=36.6141732283465, Blast_Score=249, Evalue=4e-67,
Organism=Caenorhabditis elegans, GI17509797, Length=334, Percent_Identity=29.940119760479, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17509795, Length=334, Percent_Identity=29.940119760479, Blast_Score=125, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6324082, Length=319, Percent_Identity=30.0940438871473, Blast_Score=132, Evalue=1e-31,
Organism=Drosophila melanogaster, GI19922218, Length=412, Percent_Identity=31.0679611650485, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI19922364, Length=327, Percent_Identity=30.5810397553517, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 56103; Mature: 55972

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTPLKLFNSLTRSLEEFQPIHPGEARVYTCGPTVYNYQHIGNMRAYIFADTLGRTLSW
CCCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEECHHHHCCEEEEEEEHHHCCCCCC
KGFDLKHVINITDVGHLTSDADAGDDKMEKAAAREGKSAWDIARYYQQVFEADLDRLNIR
CCCCHHHEEEEHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
KPEHPRATDYVESMIAWAKSIEAKHCYELDSGLYFDVSTVPEYGRLARAVTDEGEGRIDE
CCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEC
VEGKRNAADFAIWRKTPPGETRQMEWDSPWGKGAPGWHLECSVMSAELLGHPFDIHTGGI
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCEECCCCC
DHREIHHPNEIAQNQAHNCSPDSGAKIWMHNNFLIDRRGKMSKSSGEFLTLQALVDRGFH
CCHHCCCCHHHHHCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCEEEHHHHHHCCCC
PLAYRMLCLQAHYRSELEFTWEGLEAALVRLKRMVMALETLKARHAELVSASMPNSKPWA
HHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
QMEAWTLKQVQGDDWGKLGPAIEKFGTAIADDLNTAISLTAMEDLLATKKIDPAKKLVLA
HHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCHHHHHHHH
SAFDAVLGFDLLNLSRTDLRTRPATAEISEAEIEAAFAERKEARAAKDFARSDAIRDDLA
HHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKGVEVMDGDPLGWEWKRGT
HCCCEEECCCCCCCCCCCCC
>Mature Secondary Structure 
TTTPLKLFNSLTRSLEEFQPIHPGEARVYTCGPTVYNYQHIGNMRAYIFADTLGRTLSW
CCCHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEECHHHHCCEEEEEEEHHHCCCCCC
KGFDLKHVINITDVGHLTSDADAGDDKMEKAAAREGKSAWDIARYYQQVFEADLDRLNIR
CCCCHHHEEEEHHCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCC
KPEHPRATDYVESMIAWAKSIEAKHCYELDSGLYFDVSTVPEYGRLARAVTDEGEGRIDE
CCCCCCHHHHHHHHHHHHHHCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHCCCCCCEEC
VEGKRNAADFAIWRKTPPGETRQMEWDSPWGKGAPGWHLECSVMSAELLGHPFDIHTGGI
CCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHCCCCCEECCCCC
DHREIHHPNEIAQNQAHNCSPDSGAKIWMHNNFLIDRRGKMSKSSGEFLTLQALVDRGFH
CCHHCCCCHHHHHCCCCCCCCCCCCEEEEECCEEEECCCCCCCCCCCEEEHHHHHHCCCC
PLAYRMLCLQAHYRSELEFTWEGLEAALVRLKRMVMALETLKARHAELVSASMPNSKPWA
HHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCH
QMEAWTLKQVQGDDWGKLGPAIEKFGTAIADDLNTAISLTAMEDLLATKKIDPAKKLVLA
HHHHHHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHEEHHHHHHHHHHCCCCHHHHHHHH
SAFDAVLGFDLLNLSRTDLRTRPATAEISEAEIEAAFAERKEARAAKDFARSDAIRDDLA
HHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKGVEVMDGDPLGWEWKRGT
HCCCEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA