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The map label for this gene is nudC [H]

Identifier: 85374540

GI number: 85374540

Start: 1751181

End: 1752074

Strand: Reverse

Name: nudC [H]

Synonym: ELI_08565

Alternate gene names: 85374540

Gene position: 1752074-1751181 (Counterclockwise)

Preceding gene: 85374541

Following gene: 85374539

Centisome position: 57.4

GC content: 66.44

Gene sequence:

>894_bases
ATGGCGGCGGGCAGCCCGACCGGACAGATTTTCTTCGCCGGATCGCCGATCGATCGCGCGGATAATCTGCGCGCCGATCC
CGATGCGCTGGCTGGGCTCATGAACTGGAAGGCGCGGTTGCTCGCGCTCGACGGGCTGTTTCCCGCGCTCGACGACGACC
ACCGGCTGCGATGGGGCACTTTGGCCGACGCGCCGGAGGATGCCGAGCTGGTGTTCCTCGGCCTCGACCGCACGGACGGC
GGCGAGCGGGCCTGTTTCGCTGCGGTGCCGGACAAGGGCGATGCCAGCCCACGCATGGCAAATCCGCAGCTCTGGTCGCT
GATGGCGACGCTCGATCCGGGTGATCTGGCGACCTATGGCGGCGCGCGCAGTCTGATCGACTGGCACGCGCGGCATCGCT
TCTGCGCGCAATGCGGTTCGGACACCAAGCTCGCCAAGGGCGGCTGGCAACGCGGCTGCGAGGCGTGCGGCGCGCAGCAT
TTCCCGCGCACCGATCCGGTCACGATCATGCTGGTCGAGCACGACGGGCGATTGATGCTCGGGCGTGGGCTCGGGTGGCC
CGAAGGTGCCTTTTCCGCGCTTGCCGGATTCGTGGAGCCGGGCGAGACGATCGAAGAGGCAGTAGCGCGCGAAGTGTTCG
AGGAATCCGGCGTGCGGGTGCGCGATGTGGCCTATGTCGCGAGCCAGCCATGGCCGTTCCCCAGCCAGCTCATGATCGGA
TGCCACAGCCATGCCGACAACGACGAATTGACCATCGACGAAACCGAGATGGCCGAGGTCGTTTTCTTCAGCCGCGAGGA
CGTGGTATCGTCGCTGAACGGCGATGGCCCGTTCCGCGCGCCGCCCAAACACGCGATCGCGCACAATCTGATGCAATGGT
GGTTGAACAAATGA

Upstream 100 bases:

>100_bases
CCGGGCTCTACACGCAATACATGCCGACCGAAGCCTACCCGATGCGGCAGGACTTCATGCAGGCGCTGACGGGCGAGATG
GCCGGGGCTGCAAGCTCCTG

Downstream 100 bases:

>100_bases
CCGAGACAGATCCGCGCCGCATGACGATCGACATCTGGTCCGACGTGATGTGTCCCTGGTGCGCGATCGGTTACGGGCAG
CTGCAAAAGGCGCTCGGCCA

Product: hydrolase, NUDIX family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 296

Protein sequence:

>297_residues
MAAGSPTGQIFFAGSPIDRADNLRADPDALAGLMNWKARLLALDGLFPALDDDHRLRWGTLADAPEDAELVFLGLDRTDG
GERACFAAVPDKGDASPRMANPQLWSLMATLDPGDLATYGGARSLIDWHARHRFCAQCGSDTKLAKGGWQRGCEACGAQH
FPRTDPVTIMLVEHDGRLMLGRGLGWPEGAFSALAGFVEPGETIEEAVAREVFEESGVRVRDVAYVASQPWPFPSQLMIG
CHSHADNDELTIDETEMAEVVFFSREDVVSSLNGDGPFRAPPKHAIAHNLMQWWLNK

Sequences:

>Translated_297_residues
MAAGSPTGQIFFAGSPIDRADNLRADPDALAGLMNWKARLLALDGLFPALDDDHRLRWGTLADAPEDAELVFLGLDRTDG
GERACFAAVPDKGDASPRMANPQLWSLMATLDPGDLATYGGARSLIDWHARHRFCAQCGSDTKLAKGGWQRGCEACGAQH
FPRTDPVTIMLVEHDGRLMLGRGLGWPEGAFSALAGFVEPGETIEEAVAREVFEESGVRVRDVAYVASQPWPFPSQLMIG
CHSHADNDELTIDETEMAEVVFFSREDVVSSLNGDGPFRAPPKHAIAHNLMQWWLNK
>Mature_296_residues
AAGSPTGQIFFAGSPIDRADNLRADPDALAGLMNWKARLLALDGLFPALDDDHRLRWGTLADAPEDAELVFLGLDRTDGG
ERACFAAVPDKGDASPRMANPQLWSLMATLDPGDLATYGGARSLIDWHARHRFCAQCGSDTKLAKGGWQRGCEACGAQHF
PRTDPVTIMLVEHDGRLMLGRGLGWPEGAFSALAGFVEPGETIEEAVAREVFEESGVRVRDVAYVASQPWPFPSQLMIGC
HSHADNDELTIDETEMAEVVFFSREDVVSSLNGDGPFRAPPKHAIAHNLMQWWLNK

Specific function: Unknown

COG id: COG2816

COG function: function code L; NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI13899267, Length=200, Percent_Identity=45.5, Blast_Score=174, Evalue=1e-43,
Organism=Homo sapiens, GI50593112, Length=208, Percent_Identity=37.0192307692308, Blast_Score=145, Evalue=5e-35,
Organism=Escherichia coli, GI48994995, Length=158, Percent_Identity=36.0759493670886, Blast_Score=123, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71986510, Length=196, Percent_Identity=29.0816326530612, Blast_Score=84, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI212645999, Length=196, Percent_Identity=29.0816326530612, Blast_Score=83, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6321371, Length=196, Percent_Identity=31.6326530612245, Blast_Score=102, Evalue=8e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015375
- InterPro:   IPR022925
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR015376 [H]

Pfam domain/function: PF00293 NUDIX; PF09296 NUDIX-like; PF09297 zf-NADH-PPase [H]

EC number: =3.6.1.22 [H]

Molecular weight: Translated: 32354; Mature: 32222

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAGSPTGQIFFAGSPIDRADNLRADPDALAGLMNWKARLLALDGLFPALDDDHRLRWGT
CCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEECC
LADAPEDAELVFLGLDRTDGGERACFAAVPDKGDASPRMANPQLWSLMATLDPGDLATYG
CCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHEECCCCCCHHHCC
GARSLIDWHARHRFCAQCGSDTKLAKGGWQRGCEACGAQHFPRTDPVTIMLVEHDGRLML
CHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEE
GRGLGWPEGAFSALAGFVEPGETIEEAVAREVFEESGVRVRDVAYVASQPWPFPSQLMIG
ECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHEE
CHSHADNDELTIDETEMAEVVFFSREDVVSSLNGDGPFRAPPKHAIAHNLMQWWLNK
ECCCCCCCCEEECHHHHHHHHEECHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AAGSPTGQIFFAGSPIDRADNLRADPDALAGLMNWKARLLALDGLFPALDDDHRLRWGT
CCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEECC
LADAPEDAELVFLGLDRTDGGERACFAAVPDKGDASPRMANPQLWSLMATLDPGDLATYG
CCCCCCCCEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCHHHHHEECCCCCCHHHCC
GARSLIDWHARHRFCAQCGSDTKLAKGGWQRGCEACGAQHFPRTDPVTIMLVEHDGRLML
CHHHHHHHHHHHHHHHHCCCCCCHHCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEE
GRGLGWPEGAFSALAGFVEPGETIEEAVAREVFEESGVRVRDVAYVASQPWPFPSQLMIG
ECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCHHHHHEE
CHSHADNDELTIDETEMAEVVFFSREDVVSSLNGDGPFRAPPKHAIAHNLMQWWLNK
ECCCCCCCCEEECHHHHHHHHEECHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]