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The map label for this gene is btuC [H]

Identifier: 85374417

GI number: 85374417

Start: 1645748

End: 1646701

Strand: Reverse

Name: btuC [H]

Synonym: ELI_07950

Alternate gene names: 85374417

Gene position: 1646701-1645748 (Counterclockwise)

Preceding gene: 85374418

Following gene: 85374416

Centisome position: 53.95

GC content: 68.24

Gene sequence:

>954_bases
GTGAACCGCGCCACACGTCTCTTTCTCGCTCTCCTCGTCATTGCATTCCCGCTCTCGCTGCTGGCGGGGCGCGTGTGGCT
CGACCCGGCGAGCACGCCCAACGCCGCCGTCATCCTCGCCGAATTGCGCCTGCCCCGCGCGGTGCTGGCGGTGACGATCG
GCGCGGGGCTGGGCGCGGCGGGGGCGGCGATGCAGGGCTATTTGCGCAACCCGCTCGCCGATCCCGGACTGTTCGGTATC
GCGCCAGGCGCGGCGCTGGGCGCGGTGACGAGCTTCTGGTTCGGCTACGCTGCCTCGCCTTACCTCCTGCCGCTTTTTGC
GCTGGTCGGTGCAGGCGGCGCGATGGCGCTGCTGGCCCTGATCGCCGGGCGCACGGGAGGGATCGCGCTGTTCACTCTGG
CGGGACTCATGATTGCCAGCCTTGCCGGCGCCCTGACCAGCCTCGCCATCAGCCTTGCGCCCAACGCCTTTGCCATGAGC
CAGATCGTGACCTGGTTGATGGGCGCATTGACCGATCGCAGCTGGCAGGATGTCTACCTTGCCGCGCCGCTTACTCTGCT
CGGGATCGCGTGTCTGTGGCGGACGGCCAGGGCACTCGATGCGCTCACGCTGGGCGATGCTGCTGCGCGCTCGCTAGGGA
TCGAGCCGGGCCGGCTGTTGTTCTGGCTTATCCTCGGCATCGGTCTCACCGTCGGCAGCGGCGTTGCGGTAGCCGGCATC
ATCGGTTTCGTCGGTTTGATCGTGCCGCATCTCGTGCGCACGCTGACCGATCGCACGCCGTCGCAATTGCTGCTGCCGAG
CGCGCTCGCGGGCGCGGTGCTGGTGCTGGTGGCGGACAGTGTGGTGCGCATCCTTCCCCTCGTCACCGAACTGCGCCTCG
GAATCGCGCTCAGCCTTATTGGCGCGCCGTTCTTCCTGTGGCTGCTTCTGCGGATGAGAAGGGGCCTCGCATGA

Upstream 100 bases:

>100_bases
AGCTGAACGAGCTGCGAACCGAGCGTTTCGATGCCAATCTGCTCTATTGCGGCGGGCCGAGCATAATTCGCGCGCTCGAA
CGGCTGGCGGAGCTTCGCCG

Downstream 100 bases:

>100_bases
ACCTATCCGCGCAGAACCTCGCCGTCGGAACGCGGCTGGTCGATGTCTCGCTCACGCTCGAGCCGGGCACGGTGACCGCA
ATCTGCGGTCCCAACGGTGC

Product: iron compound ABC transporter, permease protein

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNRATRLFLALLVIAFPLSLLAGRVWLDPASTPNAAVILAELRLPRAVLAVTIGAGLGAAGAAMQGYLRNPLADPGLFGI
APGAALGAVTSFWFGYAASPYLLPLFALVGAGGAMALLALIAGRTGGIALFTLAGLMIASLAGALTSLAISLAPNAFAMS
QIVTWLMGALTDRSWQDVYLAAPLTLLGIACLWRTARALDALTLGDAAARSLGIEPGRLLFWLILGIGLTVGSGVAVAGI
IGFVGLIVPHLVRTLTDRTPSQLLLPSALAGAVLVLVADSVVRILPLVTELRLGIALSLIGAPFFLWLLLRMRRGLA

Sequences:

>Translated_317_residues
MNRATRLFLALLVIAFPLSLLAGRVWLDPASTPNAAVILAELRLPRAVLAVTIGAGLGAAGAAMQGYLRNPLADPGLFGI
APGAALGAVTSFWFGYAASPYLLPLFALVGAGGAMALLALIAGRTGGIALFTLAGLMIASLAGALTSLAISLAPNAFAMS
QIVTWLMGALTDRSWQDVYLAAPLTLLGIACLWRTARALDALTLGDAAARSLGIEPGRLLFWLILGIGLTVGSGVAVAGI
IGFVGLIVPHLVRTLTDRTPSQLLLPSALAGAVLVLVADSVVRILPLVTELRLGIALSLIGAPFFLWLLLRMRRGLA
>Mature_317_residues
MNRATRLFLALLVIAFPLSLLAGRVWLDPASTPNAAVILAELRLPRAVLAVTIGAGLGAAGAAMQGYLRNPLADPGLFGI
APGAALGAVTSFWFGYAASPYLLPLFALVGAGGAMALLALIAGRTGGIALFTLAGLMIASLAGALTSLAISLAPNAFAMS
QIVTWLMGALTDRSWQDVYLAAPLTLLGIACLWRTARALDALTLGDAAARSLGIEPGRLLFWLILGIGLTVGSGVAVAGI
IGFVGLIVPHLVRTLTDRTPSQLLLPSALAGAVLVLVADSVVRILPLVTELRLGIALSLIGAPFFLWLLLRMRRGLA

Specific function: Part of the ABC transporter complex BtuCDF involved in vitamin B12 import. Involved in the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=277, Percent_Identity=38.2671480144404, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1788004, Length=302, Percent_Identity=36.0927152317881, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1790741, Length=289, Percent_Identity=36.3321799307958, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1786805, Length=284, Percent_Identity=34.1549295774648, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786347, Length=278, Percent_Identity=30.5755395683453, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786804, Length=223, Percent_Identity=30.0448430493274, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 32611; Mature: 32611

Theoretical pI: Translated: 11.60; Mature: 11.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRATRLFLALLVIAFPLSLLAGRVWLDPASTPNAAVILAELRLPRAVLAVTIGAGLGAA
CCHHHHHHHHHHHHHHHHHHHHCHHEECCCCCCCCEEEEHHHHCCHHHHHHHHCCCCCHH
GAAMQGYLRNPLADPGLFGIAPGAALGAVTSFWFGYAASPYLLPLFALVGAGGAMALLAL
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHH
IAGRTGGIALFTLAGLMIASLAGALTSLAISLAPNAFAMSQIVTWLMGALTDRSWQDVYL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHH
AAPLTLLGIACLWRTARALDALTLGDAAARSLGIEPGRLLFWLILGIGLTVGSGVAVAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
IGFVGLIVPHLVRTLTDRTPSQLLLPSALAGAVLVLVADSVVRILPLVTELRLGIALSLI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAPFFLWLLLRMRRGLA
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNRATRLFLALLVIAFPLSLLAGRVWLDPASTPNAAVILAELRLPRAVLAVTIGAGLGAA
CCHHHHHHHHHHHHHHHHHHHHCHHEECCCCCCCCEEEEHHHHCCHHHHHHHHCCCCCHH
GAAMQGYLRNPLADPGLFGIAPGAALGAVTSFWFGYAASPYLLPLFALVGAGGAMALLAL
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHH
IAGRTGGIALFTLAGLMIASLAGALTSLAISLAPNAFAMSQIVTWLMGALTDRSWQDVYL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCHHHH
AAPLTLLGIACLWRTARALDALTLGDAAARSLGIEPGRLLFWLILGIGLTVGSGVAVAGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHH
IGFVGLIVPHLVRTLTDRTPSQLLLPSALAGAVLVLVADSVVRILPLVTELRLGIALSLI
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAPFFLWLLLRMRRGLA
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA