Click here to switch to the map view.

The map label for this gene is dcp [H]

Identifier: 85374413

GI number: 85374413

Start: 1641289

End: 1643565

Strand: Direct

Name: dcp [H]

Synonym: ELI_07930

Alternate gene names: 85374413

Gene position: 1641289-1643565 (Clockwise)

Preceding gene: 85374412

Following gene: 85374420

Centisome position: 53.77

GC content: 61.97

Gene sequence:

>2277_bases
ATGAAGGCCCAGATCCTGGCCACCACCGCCGCCGCAGCCCTGCTCGCCGGCTGTCAGACATATAACGAGGGAGCCGCCAT
GGACCCGATCGCGCAAGCCGAGGCCGATGCGGCTTACAGCCCGGAAATCCCCGAGGGCAGCGGCTATTTCGCGTCCGACA
GCAGCCTGCCCTTCCTCGCCCCGGACTTCACCAAAATTTCGGAAGACGACTACATGCCGGCTTTTCAGCAGGGCATGGAC
ATCCAGAAGGCCGAAGTGCAGGCGATTATCGACAACCCTGCCGCGCCGACCTTCGAAAACACCATCGTCGCGCTGGAAAA
ATCCGGTCGCATGCTCGGCCGCGTCGCGCGCATTTTCTTCGCACTGACCGGTTCCAACACCACCGACCGGCTCGACGAGA
TCAACCGCGAAGTCGGGCCGATGCTGTCCGCACACTCGGACTCGATCACGCTCAACCCGGCGCTCTTCGAGCGCGTCAAG
GCGGTCTACGATAACCGCGCGGCCATGGCGATGACGGTCGAAGACGCCAAGTTGCTCGAAGAAACCTACAAGCAGATGGT
CCACGCGGGCGCATTGCTGACCGAGGCCGAGCGCGAGCGGGTAAAGGCAATCAATACCGAGCTTTCCACGCTGACCACCG
AATTCGGTCAGGCCGTCCGTTCGGCCACCAACGACCAGCCGCTGATCGTCGATACGCGCGCCGAACTTGCGGGCCTGTCC
GACAGCGATATCGAAGCCGCCGCCAAGCTCGCGGCAGAGAAGGGCCATGACGGCAAGTTCGCCATCGCGCTGCAAAACAC
AACGCAGCAGCCCTCGATCCCCAGCCTCGAGAACCGCGACGTGCGCGAGCGGCTGTTCAAGCTGAGCCACAACCGTGCCG
ACGGCACCAATCCCGAGCATGACACGCGCATGCTGTTGGCAAAGATCGCCACCCTGCGCGCGGAAAAGGCTGCCCTTTTC
GGCGAAGAGGACTGGGCGAGCTACACGATGTACGATCGCATGGCGCAAAAACCCGCGACGGCATTGAAGTTCATGACCGA
CATGGTCCCCGCCCTCGCCGCAACACAACGCCGCGAAGCTGCCATGCTCAACGAGCAGATCGCGTCGAAGGGCGGCAATT
TCACCGTCGAACCGTGGGACTGGTATCGTTTCGCCAACCAGATCAAGGCCGAGCGTTACGAGCTGGATGAAGATGCGATG
ATGGAATATTTCCAGCTCGACAAGGTGCTGGAAGATGGCGTCTTCTTCATGGCCGAGAAGCTCTACGGCCTCACTTTCGA
GCGGCGCACGGACCTGCCGGTCTATCACCCCGATGTATGGACCTACACCGTATTCGATGCCGACGGCAGCGAGCTCGGCC
TGTTCTATTTTGACCCGTTCCAGCGCCCGTCGAAACGCGGCGGCGCGTGGATGAGCAATTTCGTCGACCAAAGCTATCTG
TGGGGCACCAAGCCGGTGATCTACAATGTGCTCAACATCCCGAAGGCGCCCGAAGGCGAAGTGCAGCTGGTCAGCTATGA
CTGGGTCAACACGACGTTCCACGAATTCGGCCATGCGCTGCACGGCTTCTTCGCGGACCAGAAATATGAAAGCCTTTCCG
GCACGGCGACGGCACGCGATTTCGTCGAGTATCCGAGCCAGGTCCATGAAATGTGGGCGACCTGGCCGTCGGTCCTCCAG
AACTATGCCAAGCATTACGAGACCGGCGAGACGATCCCGCAGGCGATGATCGACAAGATCGAAGCCGCATCCAAGTTCAA
CCAGGGCTACGACTTCGGCGAAGTCGTCGAAGCGGCGTTGCTCGACATGAAATGGGCCGCGCTATCGCCCGAGGAAGCCG
CCGCCATCGACACGCCGGAGAAGGTCTCCGCCTTCGAACGCCGCTCGCTGGAGGAACTGGGGCTCGAGATCGACCTGGTG
CCGCCGCGCTATCGCAGCACCTATTTCAACCACATCTTCAGCAGCCCAGCCGGCTATTCGGCCGGCTATTACAGCTATCT
GTGGACCGAGATGCTCGACCGCGACAGCCGCAAGTGGTTCCGCGACAATGGCGGGCTGACGCGCGCCAATGGCGATCACT
ATCGCAAGACCGTGCTGAGCCGTGGTGGCACAATGGACTATTTTCAGATGTTCGAGAACTTCGCCGGTCGCCAGCCCAAC
GTCCAGCCGATGCTGGAAGCGCGTGGCCTGGTCGCGAGCGCCGATGGCGCGGTCGACAGCGAAGCCTCCGACGGTGCCCT
GCCGCCACGCACCACTGCGAGCACGCCCGGCGAATAA

Upstream 100 bases:

>100_bases
TAATCAATCTCCGGTTCAAGCTCGACCAGCTAAGCAACATTCAACGGCGGCGTCGCTTTCATGCGCGCCGCCAGGTCGTG
TTAGAACGAATGGAGAGATT

Downstream 100 bases:

>100_bases
CGCGTATCGGACCTAGGCGCGGCGTAGCTTGCTGCGCCACGCCAGCGACTGGCGGTTGAGCGCGGACAGATCCGCCTCAT
CCGCCAGCGCCGCCTCTCCC

Product: peptidyl-dipeptidase DCP

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 758; Mature: 758

Protein sequence:

>758_residues
MKAQILATTAAAALLAGCQTYNEGAAMDPIAQAEADAAYSPEIPEGSGYFASDSSLPFLAPDFTKISEDDYMPAFQQGMD
IQKAEVQAIIDNPAAPTFENTIVALEKSGRMLGRVARIFFALTGSNTTDRLDEINREVGPMLSAHSDSITLNPALFERVK
AVYDNRAAMAMTVEDAKLLEETYKQMVHAGALLTEAERERVKAINTELSTLTTEFGQAVRSATNDQPLIVDTRAELAGLS
DSDIEAAAKLAAEKGHDGKFAIALQNTTQQPSIPSLENRDVRERLFKLSHNRADGTNPEHDTRMLLAKIATLRAEKAALF
GEEDWASYTMYDRMAQKPATALKFMTDMVPALAATQRREAAMLNEQIASKGGNFTVEPWDWYRFANQIKAERYELDEDAM
MEYFQLDKVLEDGVFFMAEKLYGLTFERRTDLPVYHPDVWTYTVFDADGSELGLFYFDPFQRPSKRGGAWMSNFVDQSYL
WGTKPVIYNVLNIPKAPEGEVQLVSYDWVNTTFHEFGHALHGFFADQKYESLSGTATARDFVEYPSQVHEMWATWPSVLQ
NYAKHYETGETIPQAMIDKIEAASKFNQGYDFGEVVEAALLDMKWAALSPEEAAAIDTPEKVSAFERRSLEELGLEIDLV
PPRYRSTYFNHIFSSPAGYSAGYYSYLWTEMLDRDSRKWFRDNGGLTRANGDHYRKTVLSRGGTMDYFQMFENFAGRQPN
VQPMLEARGLVASADGAVDSEASDGALPPRTTASTPGE

Sequences:

>Translated_758_residues
MKAQILATTAAAALLAGCQTYNEGAAMDPIAQAEADAAYSPEIPEGSGYFASDSSLPFLAPDFTKISEDDYMPAFQQGMD
IQKAEVQAIIDNPAAPTFENTIVALEKSGRMLGRVARIFFALTGSNTTDRLDEINREVGPMLSAHSDSITLNPALFERVK
AVYDNRAAMAMTVEDAKLLEETYKQMVHAGALLTEAERERVKAINTELSTLTTEFGQAVRSATNDQPLIVDTRAELAGLS
DSDIEAAAKLAAEKGHDGKFAIALQNTTQQPSIPSLENRDVRERLFKLSHNRADGTNPEHDTRMLLAKIATLRAEKAALF
GEEDWASYTMYDRMAQKPATALKFMTDMVPALAATQRREAAMLNEQIASKGGNFTVEPWDWYRFANQIKAERYELDEDAM
MEYFQLDKVLEDGVFFMAEKLYGLTFERRTDLPVYHPDVWTYTVFDADGSELGLFYFDPFQRPSKRGGAWMSNFVDQSYL
WGTKPVIYNVLNIPKAPEGEVQLVSYDWVNTTFHEFGHALHGFFADQKYESLSGTATARDFVEYPSQVHEMWATWPSVLQ
NYAKHYETGETIPQAMIDKIEAASKFNQGYDFGEVVEAALLDMKWAALSPEEAAAIDTPEKVSAFERRSLEELGLEIDLV
PPRYRSTYFNHIFSSPAGYSAGYYSYLWTEMLDRDSRKWFRDNGGLTRANGDHYRKTVLSRGGTMDYFQMFENFAGRQPN
VQPMLEARGLVASADGAVDSEASDGALPPRTTASTPGE
>Mature_758_residues
MKAQILATTAAAALLAGCQTYNEGAAMDPIAQAEADAAYSPEIPEGSGYFASDSSLPFLAPDFTKISEDDYMPAFQQGMD
IQKAEVQAIIDNPAAPTFENTIVALEKSGRMLGRVARIFFALTGSNTTDRLDEINREVGPMLSAHSDSITLNPALFERVK
AVYDNRAAMAMTVEDAKLLEETYKQMVHAGALLTEAERERVKAINTELSTLTTEFGQAVRSATNDQPLIVDTRAELAGLS
DSDIEAAAKLAAEKGHDGKFAIALQNTTQQPSIPSLENRDVRERLFKLSHNRADGTNPEHDTRMLLAKIATLRAEKAALF
GEEDWASYTMYDRMAQKPATALKFMTDMVPALAATQRREAAMLNEQIASKGGNFTVEPWDWYRFANQIKAERYELDEDAM
MEYFQLDKVLEDGVFFMAEKLYGLTFERRTDLPVYHPDVWTYTVFDADGSELGLFYFDPFQRPSKRGGAWMSNFVDQSYL
WGTKPVIYNVLNIPKAPEGEVQLVSYDWVNTTFHEFGHALHGFFADQKYESLSGTATARDFVEYPSQVHEMWATWPSVLQ
NYAKHYETGETIPQAMIDKIEAASKFNQGYDFGEVVEAALLDMKWAALSPEEAAAIDTPEKVSAFERRSLEELGLEIDLV
PPRYRSTYFNHIFSSPAGYSAGYYSYLWTEMLDRDSRKWFRDNGGLTRANGDHYRKTVLSRGGTMDYFQMFENFAGRQPN
VQPMLEARGLVASADGAVDSEASDGALPPRTTASTPGE

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=614, Percent_Identity=26.5472312703583, Blast_Score=199, Evalue=8e-51,
Organism=Homo sapiens, GI14149738, Length=609, Percent_Identity=26.9293924466338, Blast_Score=183, Evalue=6e-46,
Organism=Homo sapiens, GI156105687, Length=443, Percent_Identity=25.9593679458239, Blast_Score=143, Evalue=8e-34,
Organism=Escherichia coli, GI1787819, Length=681, Percent_Identity=44.4933920704846, Blast_Score=596, Evalue=1e-171,
Organism=Escherichia coli, GI1789913, Length=685, Percent_Identity=29.1970802919708, Blast_Score=294, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI32565901, Length=461, Percent_Identity=22.7765726681128, Blast_Score=70, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6319793, Length=635, Percent_Identity=26.9291338582677, Blast_Score=188, Evalue=3e-48,
Organism=Saccharomyces cerevisiae, GI6322715, Length=682, Percent_Identity=21.5542521994135, Blast_Score=108, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21356111, Length=552, Percent_Identity=23.3695652173913, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI20129717, Length=437, Percent_Identity=25.1716247139588, Blast_Score=121, Evalue=2e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 84562; Mature: 84562

Theoretical pI: Translated: 4.48; Mature: 4.48

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAQILATTAAAALLAGCQTYNEGAAMDPIAQAEADAAYSPEIPEGSGYFASDSSLPFLA
CCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDFTKISEDDYMPAFQQGMDIQKAEVQAIIDNPAAPTFENTIVALEKSGRMLGRVARIFF
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
ALTGSNTTDRLDEINREVGPMLSAHSDSITLNPALFERVKAVYDNRAAMAMTVEDAKLLE
HCCCCCCHHHHHHHHHHHCCHHHCCCCCEEECHHHHHHHHHHHCCCCEEEEEHHHHHHHH
ETYKQMVHAGALLTEAERERVKAINTELSTLTTEFGQAVRSATNDQPLIVDTRAELAGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHCCCC
DSDIEAAAKLAAEKGHDGKFAIALQNTTQQPSIPSLENRDVRERLFKLSHNRADGTNPEH
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCH
DTRMLLAKIATLRAEKAALFGEEDWASYTMYDRMAQKPATALKFMTDMVPALAATQRREA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
AMLNEQIASKGGNFTVEPWDWYRFANQIKAERYELDEDAMMEYFQLDKVLEDGVFFMAEK
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LYGLTFERRTDLPVYHPDVWTYTVFDADGSELGLFYFDPFQRPSKRGGAWMSNFVDQSYL
HHCCEECCCCCCCEECCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHC
WGTKPVIYNVLNIPKAPEGEVQLVSYDWVNTTFHEFGHALHGFFADQKYESLSGTATARD
CCCCHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FVEYPSQVHEMWATWPSVLQNYAKHYETGETIPQAMIDKIEAASKFNQGYDFGEVVEAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LDMKWAALSPEEAAAIDTPEKVSAFERRSLEELGLEIDLVPPRYRSTYFNHIFSSPAGYS
HHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCC
AGYYSYLWTEMLDRDSRKWFRDNGGLTRANGDHYRKTVLSRGGTMDYFQMFENFAGRQPN
CHHHHHHHHHHHCCHHHHHHHCCCCEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
VQPMLEARGLVASADGAVDSEASDGALPPRTTASTPGE
CCHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKAQILATTAAAALLAGCQTYNEGAAMDPIAQAEADAAYSPEIPEGSGYFASDSSLPFLA
CCCEEHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDFTKISEDDYMPAFQQGMDIQKAEVQAIIDNPAAPTFENTIVALEKSGRMLGRVARIFF
CCCCCCCCCCCCCHHHHCCCCHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHH
ALTGSNTTDRLDEINREVGPMLSAHSDSITLNPALFERVKAVYDNRAAMAMTVEDAKLLE
HCCCCCCHHHHHHHHHHHCCHHHCCCCCEEECHHHHHHHHHHHCCCCEEEEEHHHHHHHH
ETYKQMVHAGALLTEAERERVKAINTELSTLTTEFGQAVRSATNDQPLIVDTRAELAGLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECHHHHCCCC
DSDIEAAAKLAAEKGHDGKFAIALQNTTQQPSIPSLENRDVRERLFKLSHNRADGTNPEH
CCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCH
DTRMLLAKIATLRAEKAALFGEEDWASYTMYDRMAQKPATALKFMTDMVPALAATQRREA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
AMLNEQIASKGGNFTVEPWDWYRFANQIKAERYELDEDAMMEYFQLDKVLEDGVFFMAEK
HHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
LYGLTFERRTDLPVYHPDVWTYTVFDADGSELGLFYFDPFQRPSKRGGAWMSNFVDQSYL
HHCCEECCCCCCCEECCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHC
WGTKPVIYNVLNIPKAPEGEVQLVSYDWVNTTFHEFGHALHGFFADQKYESLSGTATARD
CCCCHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
FVEYPSQVHEMWATWPSVLQNYAKHYETGETIPQAMIDKIEAASKFNQGYDFGEVVEAAL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
LDMKWAALSPEEAAAIDTPEKVSAFERRSLEELGLEIDLVPPRYRSTYFNHIFSSPAGYS
HHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHCCCCCCC
AGYYSYLWTEMLDRDSRKWFRDNGGLTRANGDHYRKTVLSRGGTMDYFQMFENFAGRQPN
CHHHHHHHHHHHCCHHHHHHHCCCCEECCCCHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
VQPMLEARGLVASADGAVDSEASDGALPPRTTASTPGE
CCHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]