BacMap

Definition	Erythrobacter litoralis HTCC2594 chromosome, complete genome.
Accession	NC_007722
Length	3,052,398

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The map label for this gene is bdhA [H]

Identifier: 85374248

GI number: 85374248

Start: 1473171

End: 1473929

Strand: Reverse

Name: bdhA [H]

Synonym: ELI_07105

Alternate gene names: 85374248

Gene position: 1473929-1473171 (Counterclockwise)

Preceding gene: 85374251

Following gene: 85374247

Centisome position: 48.29

GC content: 63.37

Gene sequence:

>759_bases
ATGTTCCTCGAAGGCAAGCGTGCTTTGGTAACCGGCTCGACCTCGGGCATCGGCCTCGCCGTGGCGAAGGCTCTCCACGC
GGAAGGGGCCGAAGTGGTCCTCAACGGCTTCGGCGACGACAGCGAGATTGCATCGCTGCGCGAAGAGCTTGGCGGCGCGG
CCCATTTCGGCACCGACCTGACCGACGTTGCCGCCGTCGAAGCGATGATGGCCGATGCCGGTCCGCTCGATATTCTCGTC
AACAATGCGGGCATGCAGCATGTCTCGCCGGTCGAGGATTTCCCGGTCGACAAGTGGAACCTGATCATCGCGCTCAACCT
GACAGCCGCCTTCCACACCACGCGGCTGGCCGTGCCGGCGATGCGGGACAAGGGCTGGGGACGCATCATCAATACCGCCA
GTGCCCATTCCAAAACGGCGTCGCCTTTCAAGAGTGCCTACAACGCAAGCAAGCACGGTATCGACGGCTTCACCAAGACC
ATCGCGCTGGAGCTCGCGCAGACAGGTGTGACGGCAAATTGCATCAGCCCGGGCTATGTCTGGACGCCCCTGATCGAAGG
GCAAATCCCCGACACCATGAAGGCGCGCGGCCTCAGTCGCGAGGAAGTGATCGAGGATGTCCTGCTCGCCAAGCAGCCGA
CGAAGAAATTCGTCCAGCCGCACGAGATCGGCGCGCTCGCAGTATTCCTGTGCCGCGAGGAAGCGGGCAATGTAACGGGC
GCGAACTGGAGCATCGACGGCGGCTGGACCGCCGAGTAG

Upstream 100 bases:

>100_bases
ATCCTGTCCCCTTCGTACGTTCGCCGCCTGTTTTGGCTGGACAGGGGCGGTTTTGGCCGCAAAACGACCCTCGCGTCCAT
TCAATTCACCGGAGAACCCG

Downstream 100 bases:

>100_bases
CATCGCGCAAGAAAGGGCAAACGGGTCGCATGAGAACAGGGGGCAGGGCGCTTCTCGGGCTGGTCGCGGGGCTGTCGCTC
ACCGCTTGCCAGACCATGCC

Product: 3-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 252; Mature: 252

Protein sequence:

>252_residues
MFLEGKRALVTGSTSGIGLAVAKALHAEGAEVVLNGFGDDSEIASLREELGGAAHFGTDLTDVAAVEAMMADAGPLDILV
NNAGMQHVSPVEDFPVDKWNLIIALNLTAAFHTTRLAVPAMRDKGWGRIINTASAHSKTASPFKSAYNASKHGIDGFTKT
IALELAQTGVTANCISPGYVWTPLIEGQIPDTMKARGLSREEVIEDVLLAKQPTKKFVQPHEIGALAVFLCREEAGNVTG
ANWSIDGGWTAE

Sequences:

>Translated_252_residues
MFLEGKRALVTGSTSGIGLAVAKALHAEGAEVVLNGFGDDSEIASLREELGGAAHFGTDLTDVAAVEAMMADAGPLDILV
NNAGMQHVSPVEDFPVDKWNLIIALNLTAAFHTTRLAVPAMRDKGWGRIINTASAHSKTASPFKSAYNASKHGIDGFTKT
IALELAQTGVTANCISPGYVWTPLIEGQIPDTMKARGLSREEVIEDVLLAKQPTKKFVQPHEIGALAVFLCREEAGNVTG
ANWSIDGGWTAE
>Mature_252_residues
MFLEGKRALVTGSTSGIGLAVAKALHAEGAEVVLNGFGDDSEIASLREELGGAAHFGTDLTDVAAVEAMMADAGPLDILV
NNAGMQHVSPVEDFPVDKWNLIIALNLTAAFHTTRLAVPAMRDKGWGRIINTASAHSKTASPFKSAYNASKHGIDGFTKT
IALELAQTGVTANCISPGYVWTPLIEGQIPDTMKARGLSREEVIEDVLLAKQPTKKFVQPHEIGALAVFLCREEAGNVTG
ANWSIDGGWTAE

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI7705925, Length=250, Percent_Identity=30, Blast_Score=112, Evalue=3e-25,
Organism=Homo sapiens, GI32483357, Length=254, Percent_Identity=31.1023622047244, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI66933014, Length=249, Percent_Identity=32.1285140562249, Blast_Score=107, Evalue=1e-23,
Organism=Homo sapiens, GI20149619, Length=252, Percent_Identity=32.9365079365079, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=34.468085106383, Blast_Score=101, Evalue=7e-22,
Organism=Homo sapiens, GI15277342, Length=264, Percent_Identity=28.4090909090909, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI19923817, Length=260, Percent_Identity=25.7692307692308, Blast_Score=88, Evalue=9e-18,
Organism=Homo sapiens, GI142976729, Length=218, Percent_Identity=32.5688073394495, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI31542939, Length=222, Percent_Identity=31.0810810810811, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI4504505, Length=263, Percent_Identity=25.8555133079848, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI126723750, Length=258, Percent_Identity=29.4573643410853, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI126723191, Length=181, Percent_Identity=32.0441988950276, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI7706318, Length=194, Percent_Identity=30.9278350515464, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI4758504, Length=200, Percent_Identity=33, Blast_Score=75, Evalue=4e-14,
Organism=Homo sapiens, GI5031737, Length=256, Percent_Identity=26.5625, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI33667109, Length=189, Percent_Identity=30.6878306878307, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI109715829, Length=195, Percent_Identity=31.7948717948718, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI7657478, Length=194, Percent_Identity=27.319587628866, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI4503817, Length=193, Percent_Identity=26.4248704663212, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI157739938, Length=191, Percent_Identity=25.130890052356, Blast_Score=68, Evalue=6e-12,
Organism=Homo sapiens, GI7705855, Length=197, Percent_Identity=29.4416243654822, Blast_Score=68, Evalue=8e-12,
Organism=Homo sapiens, GI44680136, Length=185, Percent_Identity=26.4864864864865, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI44680133, Length=185, Percent_Identity=26.4864864864865, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI17738292, Length=185, Percent_Identity=26.4864864864865, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87082100, Length=260, Percent_Identity=36.9230769230769, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1790717, Length=253, Percent_Identity=32.8063241106719, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1787335, Length=254, Percent_Identity=32.6771653543307, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI1788459, Length=252, Percent_Identity=32.5396825396825, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI87082160, Length=253, Percent_Identity=34.3873517786561, Blast_Score=114, Evalue=6e-27,
Organism=Escherichia coli, GI2367175, Length=254, Percent_Identity=32.6771653543307, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1789208, Length=256, Percent_Identity=29.296875, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1789378, Length=258, Percent_Identity=30.6201550387597, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1787905, Length=258, Percent_Identity=28.6821705426357, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI2367365, Length=249, Percent_Identity=29.718875502008, Blast_Score=91, Evalue=7e-20,
Organism=Escherichia coli, GI1786812, Length=261, Percent_Identity=28.735632183908, Blast_Score=87, Evalue=8e-19,
Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=26.8774703557312, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787820, Length=178, Percent_Identity=29.7752808988764, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1786701, Length=183, Percent_Identity=30.0546448087432, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787545, Length=264, Percent_Identity=25.3787878787879, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=30.1158301158301, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25147288, Length=256, Percent_Identity=29.296875, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17555706, Length=254, Percent_Identity=26.7716535433071, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17561402, Length=262, Percent_Identity=28.6259541984733, Blast_Score=90, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71994604, Length=259, Percent_Identity=28.1853281853282, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17562906, Length=270, Percent_Identity=31.8518518518519, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17564282, Length=195, Percent_Identity=34.8717948717949, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562908, Length=271, Percent_Identity=31.3653136531365, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI71994600, Length=256, Percent_Identity=27.34375, Blast_Score=84, Evalue=7e-17,
Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=29.6296296296296, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=273, Percent_Identity=28.5714285714286, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17508895, Length=195, Percent_Identity=30.2564102564103, Blast_Score=81, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=27.3408239700375, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI193204405, Length=270, Percent_Identity=30, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17531453, Length=271, Percent_Identity=30.6273062730627, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=28.8888888888889, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17568967, Length=189, Percent_Identity=30.6878306878307, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17538182, Length=259, Percent_Identity=30.8880308880309, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=26.615969581749, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=194, Percent_Identity=29.8969072164948, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193203117, Length=194, Percent_Identity=29.8969072164948, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17560220, Length=269, Percent_Identity=29.368029739777, Blast_Score=73, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=25.1851851851852, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=24.4, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=26.1363636363636, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=203, Percent_Identity=27.0935960591133, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17507613, Length=203, Percent_Identity=27.0935960591133, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=269, Percent_Identity=27.8810408921933, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=26.1992619926199, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71997402, Length=188, Percent_Identity=26.5957446808511, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=261, Percent_Identity=25.2873563218391, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=262, Percent_Identity=25.5725190839695, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=215, Percent_Identity=26.9767441860465, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=270, Percent_Identity=28.5185185185185, Blast_Score=66, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=248, Percent_Identity=27.0161290322581, Blast_Score=76, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6322227, Length=212, Percent_Identity=28.7735849056604, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324126, Length=184, Percent_Identity=25, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644339, Length=262, Percent_Identity=32.824427480916, Blast_Score=115, Evalue=4e-26,
Organism=Drosophila melanogaster, GI24639444, Length=260, Percent_Identity=30, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI28571526, Length=257, Percent_Identity=32.295719844358, Blast_Score=101, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21355319, Length=258, Percent_Identity=30.2325581395349, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI21357041, Length=257, Percent_Identity=31.5175097276265, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI23397609, Length=256, Percent_Identity=30.859375, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24643142, Length=256, Percent_Identity=28.515625, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21358495, Length=236, Percent_Identity=27.5423728813559, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI18859837, Length=203, Percent_Identity=30.0492610837438, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644337, Length=177, Percent_Identity=30.5084745762712, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI116007236, Length=236, Percent_Identity=29.6610169491525, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17737361, Length=206, Percent_Identity=31.0679611650485, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI21355631, Length=247, Percent_Identity=25.9109311740891, Blast_Score=68, Evalue=7e-12,
Organism=Drosophila melanogaster, GI28574402, Length=193, Percent_Identity=30.5699481865285, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24584744, Length=193, Percent_Identity=30.5699481865285, Blast_Score=67, Evalue=9e-12,
Organism=Drosophila melanogaster, GI24640442, Length=203, Percent_Identity=28.0788177339901, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21356301, Length=196, Percent_Identity=27.0408163265306, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28571387, Length=212, Percent_Identity=28.7735849056604, Blast_Score=65, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24641232, Length=239, Percent_Identity=27.6150627615063, Blast_Score=65, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 26622; Mature: 26622

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLEGKRALVTGSTSGIGLAVAKALHAEGAEVVLNGFGDDSEIASLREELGGAAHFGTDL
CCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHCCCCH
TDVAAVEAMMADAGPLDILVNNAGMQHVSPVEDFPVDKWNLIIALNLTAAFHTTRLAVPA
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCCCCCEEEEEEEEEHHHHHHHHEECCC
MRDKGWGRIINTASAHSKTASPFKSAYNASKHGIDGFTKTIALELAQTGVTANCISPGYV
CCCCCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEE
WTPLIEGQIPDTMKARGLSREEVIEDVLLAKQPTKKFVQPHEIGALAVFLCREEAGNVTG
EEEEECCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHCCCCCHHCCEEEEEEHHHCCCCCC
ANWSIDGGWTAE
CCEECCCCCCCC
>Mature Secondary Structure
MFLEGKRALVTGSTSGIGLAVAKALHAEGAEVVLNGFGDDSEIASLREELGGAAHFGTDL
CCCCCCEEEEECCCCCHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHCCCCH
TDVAAVEAMMADAGPLDILVNNAGMQHVSPVEDFPVDKWNLIIALNLTAAFHTTRLAVPA
HHHHHHHHHHHCCCCEEEEEECCCCCCCCCHHHCCCCCEEEEEEEEEHHHHHHHHEECCC
MRDKGWGRIINTASAHSKTASPFKSAYNASKHGIDGFTKTIALELAQTGVTANCISPGYV
CCCCCCCCEEECCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEE
WTPLIEGQIPDTMKARGLSREEVIEDVLLAKQPTKKFVQPHEIGALAVFLCREEAGNVTG
EEEEECCCCCCHHHHCCCCHHHHHHHHHHCCCCHHHCCCCCHHCCEEEEEEHHHCCCCCC
ANWSIDGGWTAE
CCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]