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The map label for this gene is hflX [H]

Identifier: 85374078

GI number: 85374078

Start: 1299707

End: 1301008

Strand: Reverse

Name: hflX [H]

Synonym: ELI_06255

Alternate gene names: 85374078

Gene position: 1301008-1299707 (Counterclockwise)

Preceding gene: 85374079

Following gene: 85374064

Centisome position: 42.62

GC content: 65.36

Gene sequence:

>1302_bases
ATGGGCGAAGTCTCGCGCGGGGCGCGGGCGCTCGTCGTGTGCCCGGACATCAGGCGCGAGAGCTACGATCTCGATCCGGA
CGCGCGCCTGGAGGAGATCACCGGGCTGACGCTGGCGATCGGTATCGAGGTTATCGAGAGCTACATCCTGCCGATCCGGC
AGGTGCAGCCCAATACGCTGCTGGGCTCCGGCCAGGTCGAGCGCGTTTCAACCGATTGCGAATTGCACGAGATCGAGCTC
GTCGTCATCGATGGCGCGCTCAGCCCGATCCAGCAGCGCAACCTCGAAGAGAAATTCAAACGCAAGGTCATCGACCGCAC
CGGGCTGATTTTGGAGATTTTCGGCGAACGCGCGGCGACGGCGGAAGGCCGCCTTCAGGTCGAGCTGGCGCATCTCGACT
ACCAACAGAGCCGCCTGGTGCGCAGCTGGACCCACCTGGAACGCCAGCGCGGCGGCTTCGGCTTCCTCGGCGGGCCGGGG
GAGACCCAGATCGAGGCCGACCGCCGGATGATCCGCCAGCGCATGGGCCGCTTGCGCAAGGAGCTGGAGCAGGTGCGCAA
GACCCGCGGCCTGCATCGCGAGCGGCGGGGGAGGGCTCCGTGGCCCGTCATCGCGCTGGTCGGTTACACCAATGCCGGCA
AGTCGACGCTGTTCAACCGCCTGACCGGCGCGGAAGTGATGGCGGAAGACCTGCTGTTCGCAACGCTCGACCCGACCATG
CGCGCGATTGCGTTGCCGGGCGTCGAGAAAGCGATCCTGTCCGATACGGTCGGCTTCATCTCCGACCTGCCGACGCAGCT
GGTCGCCGCCTTCCGCGCGACGCTGGAAGAGGTGACGGCTGCCGACCTAATCCTGCATGTGCGCGATATCGCCAATTCCT
CGAGCGCGGCGCAGAAGTCGCAGGTACTCGAGGTCCTGCAGGATCTCGGCGTGATCGACGGCGAGGACGGTGAGAGCAGC
ATTCCGATTCTCGAGGTCTGGAACAAATGGGACCTGCTCGATCAGGACAGCGCGGAGGAATTGTCCGGCGTGGCCGAGGG
CGACGATAGCGTTATTCCCGTCTCAGCAGCCACCGGTTGGCATGTCGATGTGTTGCAGGAACGGCTCGGCCAGGTGCTGA
CGGCGCAGGCGCAGACGCGCGAATTCCTGCTATCGGTCTCCGAAGGTCGCAAAATCGCATGGCTGCATCAGCACGGCGAC
GTGCTGGCGGACGAGGATGGGGGCGAGGGCGACGAAGGCCCGATGCGCAAGCTGACTGTGCGGCTCAATCCCAAGGAACT
GGGCCAGTACGAGACGCTTTAG

Upstream 100 bases:

>100_bases
TCGCTTACAAACACGCCGTTTCGACGGTGCAGCCTGCCAGTGCGGTCGACCTGACCGACTGGGAAGAGGACGAAGAAGAC
TGAGCTTCGATGATGATCTG

Downstream 100 bases:

>100_bases
CGCGCGCTATTCATCGGCCTTGACCGCCTGCCAGAGCGCTTCCTGTTCCTCGAGCGAAAGCTGCGGGAAGGTGGAGCCGG
CTTTCCCCTCCATTCCGCGA

Product: GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 433; Mature: 432

Protein sequence:

>433_residues
MGEVSRGARALVVCPDIRRESYDLDPDARLEEITGLTLAIGIEVIESYILPIRQVQPNTLLGSGQVERVSTDCELHEIEL
VVIDGALSPIQQRNLEEKFKRKVIDRTGLILEIFGERAATAEGRLQVELAHLDYQQSRLVRSWTHLERQRGGFGFLGGPG
ETQIEADRRMIRQRMGRLRKELEQVRKTRGLHRERRGRAPWPVIALVGYTNAGKSTLFNRLTGAEVMAEDLLFATLDPTM
RAIALPGVEKAILSDTVGFISDLPTQLVAAFRATLEEVTAADLILHVRDIANSSSAAQKSQVLEVLQDLGVIDGEDGESS
IPILEVWNKWDLLDQDSAEELSGVAEGDDSVIPVSAATGWHVDVLQERLGQVLTAQAQTREFLLSVSEGRKIAWLHQHGD
VLADEDGGEGDEGPMRKLTVRLNPKELGQYETL

Sequences:

>Translated_433_residues
MGEVSRGARALVVCPDIRRESYDLDPDARLEEITGLTLAIGIEVIESYILPIRQVQPNTLLGSGQVERVSTDCELHEIEL
VVIDGALSPIQQRNLEEKFKRKVIDRTGLILEIFGERAATAEGRLQVELAHLDYQQSRLVRSWTHLERQRGGFGFLGGPG
ETQIEADRRMIRQRMGRLRKELEQVRKTRGLHRERRGRAPWPVIALVGYTNAGKSTLFNRLTGAEVMAEDLLFATLDPTM
RAIALPGVEKAILSDTVGFISDLPTQLVAAFRATLEEVTAADLILHVRDIANSSSAAQKSQVLEVLQDLGVIDGEDGESS
IPILEVWNKWDLLDQDSAEELSGVAEGDDSVIPVSAATGWHVDVLQERLGQVLTAQAQTREFLLSVSEGRKIAWLHQHGD
VLADEDGGEGDEGPMRKLTVRLNPKELGQYETL
>Mature_432_residues
GEVSRGARALVVCPDIRRESYDLDPDARLEEITGLTLAIGIEVIESYILPIRQVQPNTLLGSGQVERVSTDCELHEIELV
VIDGALSPIQQRNLEEKFKRKVIDRTGLILEIFGERAATAEGRLQVELAHLDYQQSRLVRSWTHLERQRGGFGFLGGPGE
TQIEADRRMIRQRMGRLRKELEQVRKTRGLHRERRGRAPWPVIALVGYTNAGKSTLFNRLTGAEVMAEDLLFATLDPTMR
AIALPGVEKAILSDTVGFISDLPTQLVAAFRATLEEVTAADLILHVRDIANSSSAAQKSQVLEVLQDLGVIDGEDGESSI
PILEVWNKWDLLDQDSAEELSGVAEGDDSVIPVSAATGWHVDVLQERLGQVLTAQAQTREFLLSVSEGRKIAWLHQHGDV
LADEDGGEGDEGPMRKLTVRLNPKELGQYETL

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=282, Percent_Identity=36.8794326241135, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI310133116, Length=280, Percent_Identity=36.7857142857143, Blast_Score=148, Evalue=8e-36,
Organism=Homo sapiens, GI310124269, Length=261, Percent_Identity=37.5478927203065, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI310124267, Length=261, Percent_Identity=37.5478927203065, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI310124171, Length=261, Percent_Identity=37.5478927203065, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI310124169, Length=261, Percent_Identity=37.5478927203065, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1790615, Length=368, Percent_Identity=43.75, Blast_Score=264, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17561038, Length=433, Percent_Identity=32.5635103926097, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24650079, Length=419, Percent_Identity=33.6515513126492, Blast_Score=177, Evalue=1e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 47939; Mature: 47808

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGEVSRGARALVVCPDIRRESYDLDPDARLEEITGLTLAIGIEVIESYILPIRQVQPNTL
CCCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCHHHCCCCCE
LGSGQVERVSTDCELHEIELVVIDGALSPIQQRNLEEKFKRKVIDRTGLILEIFGERAAT
ECCCCCEEECCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHHHCCCEEEECCCHHCC
AEGRLQVELAHLDYQQSRLVRSWTHLERQRGGFGFLGGPGETQIEADRRMIRQRMGRLRK
CCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ELEQVRKTRGLHRERRGRAPWPVIALVGYTNAGKSTLFNRLTGAEVMAEDLLFATLDPTM
HHHHHHHHHCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCHHH
RAIALPGVEKAILSDTVGFISDLPTQLVAAFRATLEEVTAADLILHVRDIANSSSAAQKS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QVLEVLQDLGVIDGEDGESSIPILEVWNKWDLLDQDSAEELSGVAEGDDSVIPVSAATGW
HHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCC
HVDVLQERLGQVLTAQAQTREFLLSVSEGRKIAWLHQHGDVLADEDGGEGDEGPMRKLTV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEE
RLNPKELGQYETL
EECHHHCCCCCCC
>Mature Secondary Structure 
GEVSRGARALVVCPDIRRESYDLDPDARLEEITGLTLAIGIEVIESYILPIRQVQPNTL
CCCCCCCEEEEECCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHHCCHHHCCCCCE
LGSGQVERVSTDCELHEIELVVIDGALSPIQQRNLEEKFKRKVIDRTGLILEIFGERAAT
ECCCCCEEECCCCCEEEEEEEEECCCCCHHHHCCHHHHHHHHHHHHCCCEEEECCCHHCC
AEGRLQVELAHLDYQQSRLVRSWTHLERQRGGFGFLGGPGETQIEADRRMIRQRMGRLRK
CCCEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
ELEQVRKTRGLHRERRGRAPWPVIALVGYTNAGKSTLFNRLTGAEVMAEDLLFATLDPTM
HHHHHHHHHCCHHHHCCCCCCCEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHHHCCHHH
RAIALPGVEKAILSDTVGFISDLPTQLVAAFRATLEEVTAADLILHVRDIANSSSAAQKS
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
QVLEVLQDLGVIDGEDGESSIPILEVWNKWDLLDQDSAEELSGVAEGDDSVIPVSAATGW
HHHHHHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCHHHHCCCCCCCCCEEEEECCCCC
HVDVLQERLGQVLTAQAQTREFLLSVSEGRKIAWLHQHGDVLADEDGGEGDEGPMRKLTV
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCCCCEEEEE
RLNPKELGQYETL
EECHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]