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The map label for this gene is mrdB [H]

Identifier: 85373981

GI number: 85373981

Start: 1190944

End: 1192065

Strand: Reverse

Name: mrdB [H]

Synonym: ELI_05770

Alternate gene names: 85373981

Gene position: 1192065-1190944 (Counterclockwise)

Preceding gene: 85373982

Following gene: 85373980

Centisome position: 39.05

GC content: 61.23

Gene sequence:

>1122_bases
GTGAATTCGGTCATCCCCGCGCCTATCGCGCGCCAGCCTTGGGGCATGCTTATCCCGCTGATATTGCTGACCTCCTTCGG
TGGGGCAGTGCTTTTCTCGGCTGCTGGCGGCAGTTTTAGCCCTTTCGCCAGCTCCCATTTCCTGCGCTTCGGTGTATTCC
TAGTAATGGCGGCGATCATCGCGGTCATGCCGCGCGACTTCGTGAAGTTCGCAGCATATCCGGCCTATGGCGTTACCCTG
ATCCTGTTGCTCGCGGTCGAAATCGTCGGGACACTGGGCGGCGGCAGCCAGCGCTGGCTCGAACTGGGCTTCATGCGGTT
GCAGCCATCCGAGATCATGAAGCCCGTGCTCGTCGTGGCCTTGGCCAAGTTCTACGATGGTCTGCCTGTGGGTATGATTG
CAACATGGCGCGCGCTCGTTCCCGCCGCGGTCCTTATCGGCATGCCGATGGCTCTGGTCCTGATGCAACCGGATCTCGGT
ACATCGCTCGCCATCGCTTTCGGCGGGGCAGTCGTAATGTTTCTCGCTGGACTGCCCATGCGCTGGTTCGTGGCAGGCGG
AGCAGCGGCGGCGGCGGTCATCCCGCTCGCCTACTTTTTTGCCCTGCAGCCGTACCAGCAGAAGCGGGTAAACACCTTCC
TCGATCCGGAGAGCGACCCGCTCGGTACGGGCTATCACATCACGCAGTCGAAGATCGCGATCGGATCGGGGGGGTGGACT
GGCAAGGGTTTCAACGAAGGCTCGCAAAGCCACCTCAACTACCTGCCCGAGCCGCATACCGATTTCGTATTCGCCACCAT
GGCGGAAGAGTGGGGCCTGCTCGGCGGCCTGTTCGTAATCGTCATGTTCGGGCTGATCCTCGCCTGGGGGCTCAGGGTCG
CACGCCAGTCGACTTTGCGCTTCGACAAGTTACTGGCCGCGGGAATGGTCGCGACGATGTTCTTCTACATCGCGATCAAC
CTGATGATGGTGATGGGCCTTGCGCCCGTGGTGGGTATTCCGCTGCCCTTCATGAGCCACGGCGGTTCGTCCATGCTGAC
CAACATGATCTGTATCGGCAGCCTGATGATGGTGAACCGCTGGAACCGCTCCAGCGCCCCGCGCGGTTTTATGTCGACTT
AG

Upstream 100 bases:

>100_bases
AAGCGCGCATGGCCGCGCAACAGGCGGAGGCTCTGGGGCAAGAAGCCAGCATCAGTCGCAACGAGAGCGCGCGCGGCACC
GAGCCGGCCGGGGGGAACCG

Downstream 100 bases:

>100_bases
CCCTTGCACCCAGGCTGCAAATCGCTAAATGACGCGCCTCCCGTCAATCGGGCCCTGCCGGATACCGGTAGCGTGGACGC
ATAGCTCAGTTGGTAGAGCA

Product: rod shape-determining protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 373; Mature: 373

Protein sequence:

>373_residues
MNSVIPAPIARQPWGMLIPLILLTSFGGAVLFSAAGGSFSPFASSHFLRFGVFLVMAAIIAVMPRDFVKFAAYPAYGVTL
ILLLAVEIVGTLGGGSQRWLELGFMRLQPSEIMKPVLVVALAKFYDGLPVGMIATWRALVPAAVLIGMPMALVLMQPDLG
TSLAIAFGGAVVMFLAGLPMRWFVAGGAAAAAVIPLAYFFALQPYQQKRVNTFLDPESDPLGTGYHITQSKIAIGSGGWT
GKGFNEGSQSHLNYLPEPHTDFVFATMAEEWGLLGGLFVIVMFGLILAWGLRVARQSTLRFDKLLAAGMVATMFFYIAIN
LMMVMGLAPVVGIPLPFMSHGGSSMLTNMICIGSLMMVNRWNRSSAPRGFMST

Sequences:

>Translated_373_residues
MNSVIPAPIARQPWGMLIPLILLTSFGGAVLFSAAGGSFSPFASSHFLRFGVFLVMAAIIAVMPRDFVKFAAYPAYGVTL
ILLLAVEIVGTLGGGSQRWLELGFMRLQPSEIMKPVLVVALAKFYDGLPVGMIATWRALVPAAVLIGMPMALVLMQPDLG
TSLAIAFGGAVVMFLAGLPMRWFVAGGAAAAAVIPLAYFFALQPYQQKRVNTFLDPESDPLGTGYHITQSKIAIGSGGWT
GKGFNEGSQSHLNYLPEPHTDFVFATMAEEWGLLGGLFVIVMFGLILAWGLRVARQSTLRFDKLLAAGMVATMFFYIAIN
LMMVMGLAPVVGIPLPFMSHGGSSMLTNMICIGSLMMVNRWNRSSAPRGFMST
>Mature_373_residues
MNSVIPAPIARQPWGMLIPLILLTSFGGAVLFSAAGGSFSPFASSHFLRFGVFLVMAAIIAVMPRDFVKFAAYPAYGVTL
ILLLAVEIVGTLGGGSQRWLELGFMRLQPSEIMKPVLVVALAKFYDGLPVGMIATWRALVPAAVLIGMPMALVLMQPDLG
TSLAIAFGGAVVMFLAGLPMRWFVAGGAAAAAVIPLAYFFALQPYQQKRVNTFLDPESDPLGTGYHITQSKIAIGSGGWT
GKGFNEGSQSHLNYLPEPHTDFVFATMAEEWGLLGGLFVIVMFGLILAWGLRVARQSTLRFDKLLAAGMVATMFFYIAIN
LMMVMGLAPVVGIPLPFMSHGGSSMLTNMICIGSLMMVNRWNRSSAPRGFMST

Specific function: This is one of the proteins responsible for the rod shape of the cell. It is required for the expression of the enzymatic activity of PBP2, which is thought to synthesize peptidoglycan in the step of initiation of cell elongation [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786853, Length=313, Percent_Identity=44.0894568690096, Blast_Score=232, Evalue=2e-62,
Organism=Escherichia coli, GI1786277, Length=334, Percent_Identity=32.0359281437126, Blast_Score=151, Evalue=6e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR011923 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 40000; Mature: 40000

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
6.7 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
6.7 %Met     (Mature Protein)
7.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSVIPAPIARQPWGMLIPLILLTSFGGAVLFSAAGGSFSPFASSHFLRFGVFLVMAAII
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
AVMPRDFVKFAAYPAYGVTLILLLAVEIVGTLGGGSQRWLELGFMRLQPSEIMKPVLVVA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECHHHHHHHHHHHH
LAKFYDGLPVGMIATWRALVPAAVLIGMPMALVLMQPDLGTSLAIAFGGAVVMFLAGLPM
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHCCCCH
RWFVAGGAAAAAVIPLAYFFALQPYQQKRVNTFLDPESDPLGTGYHITQSKIAIGSGGWT
HHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEECCEEEECCCCCC
GKGFNEGSQSHLNYLPEPHTDFVFATMAEEWGLLGGLFVIVMFGLILAWGLRVARQSTLR
CCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDKLLAAGMVATMFFYIAINLMMVMGLAPVVGIPLPFMSHGGSSMLTNMICIGSLMMVNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHC
WNRSSAPRGFMST
CCCCCCCCCCCCC
>Mature Secondary Structure
MNSVIPAPIARQPWGMLIPLILLTSFGGAVLFSAAGGSFSPFASSHFLRFGVFLVMAAII
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHH
AVMPRDFVKFAAYPAYGVTLILLLAVEIVGTLGGGSQRWLELGFMRLQPSEIMKPVLVVA
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHEECHHHHHHHHHHHH
LAKFYDGLPVGMIATWRALVPAAVLIGMPMALVLMQPDLGTSLAIAFGGAVVMFLAGLPM
HHHHHCCCCHHHHHHHHHHHHHHHHHHCCHHHEEECCCCCCHHHHHHHHHHHHHHCCCCH
RWFVAGGAAAAAVIPLAYFFALQPYQQKRVNTFLDPESDPLGTGYHITQSKIAIGSGGWT
HHHHCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCEEEECCEEEECCCCCC
GKGFNEGSQSHLNYLPEPHTDFVFATMAEEWGLLGGLFVIVMFGLILAWGLRVARQSTLR
CCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FDKLLAAGMVATMFFYIAINLMMVMGLAPVVGIPLPFMSHGGSSMLTNMICIGSLMMVNR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHC
WNRSSAPRGFMST
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]