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The map label for this gene is erg3 [H]

Identifier: 85373959

GI number: 85373959

Start: 1169754

End: 1170653

Strand: Reverse

Name: erg3 [H]

Synonym: ELI_05660

Alternate gene names: 85373959

Gene position: 1170653-1169754 (Counterclockwise)

Preceding gene: 85373960

Following gene: 85373958

Centisome position: 38.35

GC content: 59.33

Gene sequence:

>900_bases
ATGGAGAGTATAGAAAGCGCCATCGCATTCATCGGCGGCCCGGCTGCCTTGTGGATTCTTGCGTCGGTCTATTTCGGCAG
TGTCATTGTCGAACGAGTCTGGGCGCTGTGGGGAAATCCCGACTACGACAACAAGGACGCGCTGTGCTCGATCGGGCTCA
ACCTTATCAGTAGCGTCCTCAATCTCGTCATAGCGATCCTGATCCCGCTCGCGCTCTATGTGGCGGTGTTCGACAATCTT
CGTCTCGTTTCCGAAATGTCGCTGCTGCTGGCAATTCCGCTCGCCTTCCTGTTTCACGAACTGGCCTATTACTGGGACCA
TCGCCTGGCGCACCGGATCGGCCTGCTTTGGGCTTTTCACGCGATCCATCACTCGTCGAACGAGTTCAACCATTCGACCG
CAGCGCGCGGGTTCGTTTTCGACGGGCAGCTCAAGAACCTGTTCGCCCTACCCGCGGCGTTCGTCGGAATCGATCCGGTC
GTTTACATCGCGGTCAGCGTCTGCACCAATGCCTTCGGTATCTGGAACCACGCGAGCTATGTCCCGCGGATGGGCTGGAT
CGACCGGGTGCTCATGACGCCGAAGATGCACAAGGTCCATCACGCCAACCAGCCCCAATATATCGACCGCAATTACAGCC
AGGTCACGCTACTCTACGACCGCCTGTTCGGATCGGTCGCCCATCTCGCGGAAGAACCCGACCCCGGCCTCGTCAAGCGG
GTCTACGACAATAATCCGCTCACCGCGCAATTCGCCGGGTTGAAGCAACTCAAGGACCGCATGGATCACGCAGAGCGCTG
GCAGGACAAACTGGCCTATCTCTGGCGTCCGCCCGAATGGTCGCACGATGGCGTCTGCCGTTCCGACTGTCCGAAATACG
GAGCGCTCCCGGCGTCCTGA

Upstream 100 bases:

>100_bases
CCGGCAGATCGAGGCCAAGGCGCTGCGCAAGCTCAAGCACCCGAGCCGCAGCCGCAAGATGCGGTCTTTCCTGGATCAAT
AAAACCGCTAGGATCAGGCG

Downstream 100 bases:

>100_bases
TTGAAGATAAGGCCTCCGGACGGGGTCGCACGAATCGCCCCGCTCGCCTATGGCGACGCGCATGAAGATAGCGATCGCAT
CCGACCACGCCGCCGTCGAG

Product: hypothetical protein

Products: NA

Alternate protein names: Sterol-C5-desaturase [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MESIESAIAFIGGPAALWILASVYFGSVIVERVWALWGNPDYDNKDALCSIGLNLISSVLNLVIAILIPLALYVAVFDNL
RLVSEMSLLLAIPLAFLFHELAYYWDHRLAHRIGLLWAFHAIHHSSNEFNHSTAARGFVFDGQLKNLFALPAAFVGIDPV
VYIAVSVCTNAFGIWNHASYVPRMGWIDRVLMTPKMHKVHHANQPQYIDRNYSQVTLLYDRLFGSVAHLAEEPDPGLVKR
VYDNNPLTAQFAGLKQLKDRMDHAERWQDKLAYLWRPPEWSHDGVCRSDCPKYGALPAS

Sequences:

>Translated_299_residues
MESIESAIAFIGGPAALWILASVYFGSVIVERVWALWGNPDYDNKDALCSIGLNLISSVLNLVIAILIPLALYVAVFDNL
RLVSEMSLLLAIPLAFLFHELAYYWDHRLAHRIGLLWAFHAIHHSSNEFNHSTAARGFVFDGQLKNLFALPAAFVGIDPV
VYIAVSVCTNAFGIWNHASYVPRMGWIDRVLMTPKMHKVHHANQPQYIDRNYSQVTLLYDRLFGSVAHLAEEPDPGLVKR
VYDNNPLTAQFAGLKQLKDRMDHAERWQDKLAYLWRPPEWSHDGVCRSDCPKYGALPAS
>Mature_299_residues
MESIESAIAFIGGPAALWILASVYFGSVIVERVWALWGNPDYDNKDALCSIGLNLISSVLNLVIAILIPLALYVAVFDNL
RLVSEMSLLLAIPLAFLFHELAYYWDHRLAHRIGLLWAFHAIHHSSNEFNHSTAARGFVFDGQLKNLFALPAAFVGIDPV
VYIAVSVCTNAFGIWNHASYVPRMGWIDRVLMTPKMHKVHHANQPQYIDRNYSQVTLLYDRLFGSVAHLAEEPDPGLVKR
VYDNNPLTAQFAGLKQLKDRMDHAERWQDKLAYLWRPPEWSHDGVCRSDCPKYGALPAS

Specific function: Unknown

COG id: COG3000

COG function: function code I; Sterol desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sterol desaturase family [H]

Homologues:

Organism=Homo sapiens, GI51972212, Length=252, Percent_Identity=31.7460317460317, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI25144659, Length=220, Percent_Identity=29.5454545454545, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006694 [H]

Pfam domain/function: PF04116 FA_hydroxylase [H]

EC number: NA

Molecular weight: Translated: 33740; Mature: 33740

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESIESAIAFIGGPAALWILASVYFGSVIVERVWALWGNPDYDNKDALCSIGLNLISSVL
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
NLVIAILIPLALYVAVFDNLRLVSEMSLLLAIPLAFLFHELAYYWDHRLAHRIGLLWAFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIHHSSNEFNHSTAARGFVFDGQLKNLFALPAAFVGIDPVVYIAVSVCTNAFGIWNHASY
HHHHCCCCCCCHHHHCCCEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHH
VPRMGWIDRVLMTPKMHKVHHANQPQYIDRNYSQVTLLYDRLFGSVAHLAEEPDPGLVKR
CCCHHHHHHHHHCCCHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VYDNNPLTAQFAGLKQLKDRMDHAERWQDKLAYLWRPPEWSHDGVCRSDCPKYGALPAS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCC
>Mature Secondary Structure
MESIESAIAFIGGPAALWILASVYFGSVIVERVWALWGNPDYDNKDALCSIGLNLISSVL
CCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
NLVIAILIPLALYVAVFDNLRLVSEMSLLLAIPLAFLFHELAYYWDHRLAHRIGLLWAFH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIHHSSNEFNHSTAARGFVFDGQLKNLFALPAAFVGIDPVVYIAVSVCTNAFGIWNHASY
HHHHCCCCCCCHHHHCCCEECCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHH
VPRMGWIDRVLMTPKMHKVHHANQPQYIDRNYSQVTLLYDRLFGSVAHLAEEPDPGLVKR
CCCHHHHHHHHHCCCHHHHHCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
VYDNNPLTAQFAGLKQLKDRMDHAERWQDKLAYLWRPPEWSHDGVCRSDCPKYGALPAS
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]