Click here to switch to the map view.

The map label for this gene is ilvH

Identifier: 85373929

GI number: 85373929

Start: 1144699

End: 1145214

Strand: Reverse

Name: ilvH

Synonym: ELI_05510

Alternate gene names: 85373929

Gene position: 1145214-1144699 (Counterclockwise)

Preceding gene: 85373930

Following gene: 85373928

Centisome position: 37.52

GC content: 62.02

Gene sequence:

>516_bases
ATGAAGATCACAGCGAAAGAGGCCGAGCGCCATGTGCTCGCCGTCACCGTCGATAATGAGCCGGGTATCCTCGCCAAAAT
TACCGGGCTGTTCACTGCGCGCGGCTACAATATCGACAGCCTGACAGTCGCGGACATCACTGAAGACCACGCCATCAGCC
GAATTACGGTAGTCACCAATGGACCGCCCGAAGTGATCGACCAAATCCAGGCGCAGCTTGAGCGCTTGGTGCCGGTTCAT
CGCGTCGTCGACCTGTCCGAAGCCGGCCCGCATGTCGAACGCGAGCTGGCGTTGGTAAAAGTCTCCGGCACCGGCGAGAA
ACGCGTCGAAGCACTGCGCCTGGCCGACATTTTCCGCGCGCGGCCCGTCGACACGACGACCGAGAGCTTTATTTTCGAGA
TCACCGGCCCGCCGGACAAGGTCGACAGCTTCATCGCCCTGATGCGCGAACTCGGCCTTGTCGAAGTCGGCCGGACCGGG
ATCGTCGGCATGATGCGCGGGGCGGAGGCGCTTTGA

Upstream 100 bases:

>100_bases
CCCGAGCGGGGCTGCGCATACCGACATGCTGCTTTATGGCGACCAGGTCGAAGGCACGATGGACGACGAAGCCAAGGCTT
TGGTGTAAAGGGCAGCCACC

Downstream 100 bases:

>100_bases
GAAGTTTCGTCATCCCAGCGAAAGCTGGGATCTCGCGTTGCAAGGCGCGACCGAGGATAACCAGATCCCGGCTTTCGCTG
GGATGACGTGAGGGAAGAAC

Product: acetolactate synthase 3 regulatory subunit

Products: NA

Alternate protein names: Acetohydroxy-acid synthase small subunit; AHAS; ALS [H]

Number of amino acids: Translated: 171; Mature: 171

Protein sequence:

>171_residues
MKITAKEAERHVLAVTVDNEPGILAKITGLFTARGYNIDSLTVADITEDHAISRITVVTNGPPEVIDQIQAQLERLVPVH
RVVDLSEAGPHVERELALVKVSGTGEKRVEALRLADIFRARPVDTTTESFIFEITGPPDKVDSFIALMRELGLVEVGRTG
IVGMMRGAEAL

Sequences:

>Translated_171_residues
MKITAKEAERHVLAVTVDNEPGILAKITGLFTARGYNIDSLTVADITEDHAISRITVVTNGPPEVIDQIQAQLERLVPVH
RVVDLSEAGPHVERELALVKVSGTGEKRVEALRLADIFRARPVDTTTESFIFEITGPPDKVDSFIALMRELGLVEVGRTG
IVGMMRGAEAL
>Mature_171_residues
MKITAKEAERHVLAVTVDNEPGILAKITGLFTARGYNIDSLTVADITEDHAISRITVVTNGPPEVIDQIQAQLERLVPVH
RVVDLSEAGPHVERELALVKVSGTGEKRVEALRLADIFRARPVDTTTESFIFEITGPPDKVDSFIALMRELGLVEVGRTG
IVGMMRGAEAL

Specific function: Valine and isoleucine biosynthesis; first step. [C]

COG id: COG0440

COG function: function code E; Acetolactate synthase, small (regulatory) subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ACT domain [H]

Homologues:

Organism=Escherichia coli, GI1786266, Length=159, Percent_Identity=44.6540880503145, Blast_Score=135, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319837, Length=207, Percent_Identity=28.5024154589372, Blast_Score=92, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004789
- InterPro:   IPR019455
- InterPro:   IPR002912 [H]

Pfam domain/function: PF01842 ACT; PF10369 ALS_ss_C [H]

EC number: =2.2.1.6 [H]

Molecular weight: Translated: 18592; Mature: 18592

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKITAKEAERHVLAVTVDNEPGILAKITGLFTARGYNIDSLTVADITEDHAISRITVVTN
CCCCCCCCCCEEEEEEECCCCCEEEEEEEHHEECCCCCCCEEEECCCCCCCEEEEEEEEC
GPPEVIDQIQAQLERLVPVHRVVDLSEAGPHVERELALVKVSGTGEKRVEALRLADIFRA
CCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHC
RPVDTTTESFIFEITGPPDKVDSFIALMRELGLVEVGRTGIVGMMRGAEAL
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEECCCCHHHHCCCCCCC
>Mature Secondary Structure
MKITAKEAERHVLAVTVDNEPGILAKITGLFTARGYNIDSLTVADITEDHAISRITVVTN
CCCCCCCCCCEEEEEEECCCCCEEEEEEEHHEECCCCCCCEEEECCCCCCCEEEEEEEEC
GPPEVIDQIQAQLERLVPVHRVVDLSEAGPHVERELALVKVSGTGEKRVEALRLADIFRA
CCHHHHHHHHHHHHHHCHHHHHHCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHC
RPVDTTTESFIFEITGPPDKVDSFIALMRELGLVEVGRTGIVGMMRGAEAL
CCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCEEECCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]