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The map label for this gene is 85373918

Identifier: 85373918

GI number: 85373918

Start: 1134650

End: 1135432

Strand: Reverse

Name: 85373918

Synonym: ELI_05455

Alternate gene names: NA

Gene position: 1135432-1134650 (Counterclockwise)

Preceding gene: 85373919

Following gene: 85373917

Centisome position: 37.2

GC content: 63.6

Gene sequence:

>783_bases
ATGGACAACAAGACCGCCAGCGACGACGCGCATATCCGCGACACCGTCAGCGACGAAGAATGGGCGGTCCGCGTCGATCT
CGCGGCAGCCTATCGGCTGGTTGCACTCTACGGCTGGGACGACCTGATTTTTACGCACCTCTCGGCCCGCGTACCGGGGC
CGGAGCATCACTTCCTCATCAACCCCTACGACATGATGTTCGAGGAGATCACCGCCTCTTCGCTGGTGAAGATCGACACC
GAGGGACAGCCGGTCATCCCGACGTCCCATCCCGTCAATCCGGCCGGTTTCACGATCCACTCGGCGCTGCACATGAATTG
CGACGATGCCCATGCGGTAATGCACCTCCATACGCCGTCCGGCCAGGCGGTCAGCGCCATGGCCGACGGGCTGATGGAGC
ACACCCAGACCGGCATGATCGCGCGCAGCGACATTGCCTATCACGAGTACGAAGGCATCGCGACCGATCTCGAGGAGCGC
GAGCGCCTGGTCGAGGACATGGGCGACAAGCACGCCATGATCCTGCGCAATCACGGCACCCTGGCGATCGGCAGGACTGT
CGGTGAATGCTTCCTGCGGCTCTATTTCATCGAGCGCGCCTGCGATGCCCAGGTCAAGATGCTGAGCGCGGGCCGCGAAA
ACCTCCATAACCCGCCGCAGGGCACGCCGGAAAAGGTCAAGGCGCAGACCCCGTCCGAGGGGATCGGCATGATCGCCAAC
GGTCTCGCTTGGCCGGCGCTGTTGCGCAAGCTCGACCGGATCGATCCGAGCTTCCGCAACTGA

Upstream 100 bases:

>100_bases
AGACCGAGCTTGCCCTGATCCCCTCCGATTGAATGCGGCGGCCAGACAGGCTACAGATTGCAAAACGAGACCCGAGAGGA
GCAGACCCATGGCCACCGTA

Downstream 100 bases:

>100_bases
CGCGCAGTGCGGCGTTTTCCTACTCGCATTCCGGCGGGTAGGAGAACCGCATGTCTCGCCGGATGCATTCACCAAAAGTT
TTCGTACCCGCACCGATGAG

Product: class II aldolase/adducin domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 260; Mature: 260

Protein sequence:

>260_residues
MDNKTASDDAHIRDTVSDEEWAVRVDLAAAYRLVALYGWDDLIFTHLSARVPGPEHHFLINPYDMMFEEITASSLVKIDT
EGQPVIPTSHPVNPAGFTIHSALHMNCDDAHAVMHLHTPSGQAVSAMADGLMEHTQTGMIARSDIAYHEYEGIATDLEER
ERLVEDMGDKHAMILRNHGTLAIGRTVGECFLRLYFIERACDAQVKMLSAGRENLHNPPQGTPEKVKAQTPSEGIGMIAN
GLAWPALLRKLDRIDPSFRN

Sequences:

>Translated_260_residues
MDNKTASDDAHIRDTVSDEEWAVRVDLAAAYRLVALYGWDDLIFTHLSARVPGPEHHFLINPYDMMFEEITASSLVKIDT
EGQPVIPTSHPVNPAGFTIHSALHMNCDDAHAVMHLHTPSGQAVSAMADGLMEHTQTGMIARSDIAYHEYEGIATDLEER
ERLVEDMGDKHAMILRNHGTLAIGRTVGECFLRLYFIERACDAQVKMLSAGRENLHNPPQGTPEKVKAQTPSEGIGMIAN
GLAWPALLRKLDRIDPSFRN
>Mature_260_residues
MDNKTASDDAHIRDTVSDEEWAVRVDLAAAYRLVALYGWDDLIFTHLSARVPGPEHHFLINPYDMMFEEITASSLVKIDT
EGQPVIPTSHPVNPAGFTIHSALHMNCDDAHAVMHLHTPSGQAVSAMADGLMEHTQTGMIARSDIAYHEYEGIATDLEER
ERLVEDMGDKHAMILRNHGTLAIGRTVGECFLRLYFIERACDAQVKMLSAGRENLHNPPQGTPEKVKAQTPSEGIGMIAN
GLAWPALLRKLDRIDPSFRN

Specific function: Unknown

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family [H]

Homologues:

Organism=Homo sapiens, GI29826325, Length=251, Percent_Identity=39.4422310756972, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI29826323, Length=251, Percent_Identity=39.4422310756972, Blast_Score=164, Evalue=6e-41,
Organism=Homo sapiens, GI29826321, Length=251, Percent_Identity=39.4422310756972, Blast_Score=164, Evalue=7e-41,
Organism=Homo sapiens, GI29826319, Length=251, Percent_Identity=39.4422310756972, Blast_Score=164, Evalue=8e-41,
Organism=Homo sapiens, GI89276787, Length=218, Percent_Identity=36.697247706422, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI297307160, Length=218, Percent_Identity=36.697247706422, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI9257190, Length=218, Percent_Identity=36.697247706422, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI297307158, Length=218, Percent_Identity=36.697247706422, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI9257192, Length=218, Percent_Identity=36.697247706422, Blast_Score=139, Evalue=4e-33,
Organism=Homo sapiens, GI9943848, Length=202, Percent_Identity=36.1386138613861, Blast_Score=131, Evalue=5e-31,
Organism=Homo sapiens, GI9951927, Length=202, Percent_Identity=36.1386138613861, Blast_Score=131, Evalue=7e-31,
Organism=Homo sapiens, GI62912453, Length=202, Percent_Identity=36.1386138613861, Blast_Score=131, Evalue=7e-31,
Organism=Caenorhabditis elegans, GI115533216, Length=255, Percent_Identity=37.2549019607843, Blast_Score=160, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI115533218, Length=255, Percent_Identity=37.2549019607843, Blast_Score=160, Evalue=8e-40,
Organism=Caenorhabditis elegans, GI71989560, Length=260, Percent_Identity=28.4615384615385, Blast_Score=113, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI71989550, Length=260, Percent_Identity=28.4615384615385, Blast_Score=113, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI71989555, Length=260, Percent_Identity=28.4615384615385, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI71989541, Length=260, Percent_Identity=28.4615384615385, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71989544, Length=260, Percent_Identity=28.4615384615385, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI281363755, Length=214, Percent_Identity=34.1121495327103, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI281363751, Length=214, Percent_Identity=34.1121495327103, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24655690, Length=214, Percent_Identity=34.1121495327103, Blast_Score=128, Evalue=5e-30,
Organism=Drosophila melanogaster, GI24655685, Length=214, Percent_Identity=34.1121495327103, Blast_Score=127, Evalue=9e-30,
Organism=Drosophila melanogaster, GI281363761, Length=214, Percent_Identity=34.1121495327103, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281363759, Length=214, Percent_Identity=34.1121495327103, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281363753, Length=214, Percent_Identity=34.1121495327103, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281363763, Length=214, Percent_Identity=34.1121495327103, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281363757, Length=214, Percent_Identity=34.1121495327103, Blast_Score=126, Evalue=1e-29,
Organism=Drosophila melanogaster, GI17136738, Length=214, Percent_Identity=34.1121495327103, Blast_Score=126, Evalue=1e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: NA

Molecular weight: Translated: 28845; Mature: 28845

Theoretical pI: Translated: 5.29; Mature: 5.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNKTASDDAHIRDTVSDEEWAVRVDLAAAYRLVALYGWDDLIFTHLSARVPGPEHHFLI
CCCCCCCCCCHHHHCCCCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEE
NPYDMMFEEITASSLVKIDTEGQPVIPTSHPVNPAGFTIHSALHMNCDDAHAVMHLHTPS
CHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCC
GQAVSAMADGLMEHTQTGMIARSDIAYHEYEGIATDLEERERLVEDMGDKHAMILRNHGT
CCHHHHHHHHHHHHHHCCCEEECCCCHHHHCCHHCCHHHHHHHHHHCCCCEEEEEECCCC
LAIGRTVGECFLRLYFIERACDAQVKMLSAGRENLHNPPQGTPEKVKAQTPSEGIGMIAN
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHH
GLAWPALLRKLDRIDPSFRN
HHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MDNKTASDDAHIRDTVSDEEWAVRVDLAAAYRLVALYGWDDLIFTHLSARVPGPEHHFLI
CCCCCCCCCCHHHHCCCCCCEEEEEEHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCEEEE
NPYDMMFEEITASSLVKIDTEGQPVIPTSHPVNPAGFTIHSALHMNCDDAHAVMHLHTPS
CHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCEEEEEEECCC
GQAVSAMADGLMEHTQTGMIARSDIAYHEYEGIATDLEERERLVEDMGDKHAMILRNHGT
CCHHHHHHHHHHHHHHCCCEEECCCCHHHHCCHHCCHHHHHHHHHHCCCCEEEEEECCCC
LAIGRTVGECFLRLYFIERACDAQVKMLSAGRENLHNPPQGTPEKVKAQTPSEGIGMIAN
EEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCHHHHH
GLAWPALLRKLDRIDPSFRN
HHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]