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The map label for this gene is yhdH [H]

Identifier: 85373897

GI number: 85373897

Start: 1107759

End: 1109198

Strand: Direct

Name: yhdH [H]

Synonym: ELI_05350

Alternate gene names: 85373897

Gene position: 1107759-1109198 (Clockwise)

Preceding gene: 85373894

Following gene: 85373898

Centisome position: 36.29

GC content: 62.85

Gene sequence:

>1440_bases
ATGGTAGCTTCAGCTTCGACCGGTAGCGCAGCGCGCGACGGATGGTCATCTCGTTCGGCGTTTATCCTTGCGGCCATCGG
TGCCGCGGTCGGTCTCGGCAATATCTGGCGCTTCCCGACGCTCGCCGGCGAAAGCGGGGGTGGGGCCTTCGTGTTCTTCT
ATATCGCCTGCGTGTTCCTGCTCGGTCTGCCGCTGGTTCTTTCCGAGGTGTTCATCGGGCGCGCGGGCCAGACCGATGCA
GTGGGTTCGATCAAGAAAGTGGCACGAGATTCCGGCGCGTCGGAAAGCTGGTCGATTTTCGGCGCGGTCGGCGCAATGGC
GGCGTTCCTGATCCTGTCGTTCTATTCGGTGGTCGCGGGCTGGGTGCTCTATTACGTCGGAGTGATGGGGGCGGACCTGC
TGGGCGCCATCGCTGCAGGCGAGCCGTTCCGTGGCGCGCTGGCGGGCGAAAGCCAGGAGGCGATTCAGGGGCGGATGGGC
AATCTCTTCGCCAGTCCGGGGCTGCTGCTTGCAATGCACCTCGTGTTCATGGGCGGCACGCTTTTCATCGTTGCGCGCGG
CATCGGTTCAGGGATCGAAAAAGCCGCGACTTGGTTGATGCCTGCATTCTTTGTCCTGCTGGTCGGCATTACCATTTACG
GCGCATTCGTGGGAGATATGGGCGATGCGATCGCATTTCTCTTCACGCCCGACTGGTCGAAGCTGACGCCTGCGGTGATG
AATTCCGCATTGGGCCAGGCGCTATTCTCACTGTCGCTCGGGGTGGCTGGTCTCATCACCTACGGTTCCTACATCAACGA
AGGCAGCAAGCTGGGCTCGACTTCGGCCACCATCGCTATCGCCGACACCAGCGTAGCTCTGCTCGCCGGCCTGATGATCT
TCCCCATCGTTTTCGCAGTCGGTCTCGATCCGGCGGCCGGCCCGACGCTGGTGTTCCAGACGCTGCCCTTCGCATTCCAG
TCGATGCCGGCAGGCGCGCTGATCGGCTTCCTCTTCTTCGTGCTGATCCTCGTCGCTGCGATCACCAGTTCGATCTCGCT
GCTCGAAGTGCCGACTGCATACGGTATCGGCGAGCGGGGCTGGAGCCGTCGCCAGTCGGCGCTCATCTTCGGTGGCGGCG
CGTTCGTCGTCGGCATCGCATGCCTGCTCGGCTACAACGTCTGGGCAGACGTGCGCCTGCTTGGCTTCTGGCCGCTGTTT
GCAGAGACAGACATCCTCGACACGATCGACGGCTTTACCGGCAAGGTGATGCTGCCGCTCGGTGCGCTGCTGACATCGGT
ATTCATCGGCTGGAAGGCCGACCGCAAGATGGTGCAGGAAGTGACCGGGCTGGAAGGGCCGATGTTTGCCATCTGGCGCT
TCCTGATCGCGTGGCTGTGTCCGCTGGCGGTGACGATCATCCTGATCACCGGCCTGTTCCCGGCGGTGCTGGGATCGTGA

Upstream 100 bases:

>100_bases
GTCCCGTTTCCTTTGGCCCTTGGCCTAGGCGCAAAATCGTTGCAGAAGGCGCGCATTACCCGCGCGAGGGGGTCGCGCGT
TGAGAGGACAAAATCACGAT

Downstream 100 bases:

>100_bases
TTTACGACATTGGCGGCGGGAGATTTGTGGAGTAATTCGCACGCCGTCGGTTGGCAGGGCGGGAGTGGCCCGCTGCGGGC
CTGACGGAATCTTCCACGAT

Product: sodium-dependent transporter, NSS family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MVASASTGSAARDGWSSRSAFILAAIGAAVGLGNIWRFPTLAGESGGGAFVFFYIACVFLLGLPLVLSEVFIGRAGQTDA
VGSIKKVARDSGASESWSIFGAVGAMAAFLILSFYSVVAGWVLYYVGVMGADLLGAIAAGEPFRGALAGESQEAIQGRMG
NLFASPGLLLAMHLVFMGGTLFIVARGIGSGIEKAATWLMPAFFVLLVGITIYGAFVGDMGDAIAFLFTPDWSKLTPAVM
NSALGQALFSLSLGVAGLITYGSYINEGSKLGSTSATIAIADTSVALLAGLMIFPIVFAVGLDPAAGPTLVFQTLPFAFQ
SMPAGALIGFLFFVLILVAAITSSISLLEVPTAYGIGERGWSRRQSALIFGGGAFVVGIACLLGYNVWADVRLLGFWPLF
AETDILDTIDGFTGKVMLPLGALLTSVFIGWKADRKMVQEVTGLEGPMFAIWRFLIAWLCPLAVTIILITGLFPAVLGS

Sequences:

>Translated_479_residues
MVASASTGSAARDGWSSRSAFILAAIGAAVGLGNIWRFPTLAGESGGGAFVFFYIACVFLLGLPLVLSEVFIGRAGQTDA
VGSIKKVARDSGASESWSIFGAVGAMAAFLILSFYSVVAGWVLYYVGVMGADLLGAIAAGEPFRGALAGESQEAIQGRMG
NLFASPGLLLAMHLVFMGGTLFIVARGIGSGIEKAATWLMPAFFVLLVGITIYGAFVGDMGDAIAFLFTPDWSKLTPAVM
NSALGQALFSLSLGVAGLITYGSYINEGSKLGSTSATIAIADTSVALLAGLMIFPIVFAVGLDPAAGPTLVFQTLPFAFQ
SMPAGALIGFLFFVLILVAAITSSISLLEVPTAYGIGERGWSRRQSALIFGGGAFVVGIACLLGYNVWADVRLLGFWPLF
AETDILDTIDGFTGKVMLPLGALLTSVFIGWKADRKMVQEVTGLEGPMFAIWRFLIAWLCPLAVTIILITGLFPAVLGS
>Mature_479_residues
MVASASTGSAARDGWSSRSAFILAAIGAAVGLGNIWRFPTLAGESGGGAFVFFYIACVFLLGLPLVLSEVFIGRAGQTDA
VGSIKKVARDSGASESWSIFGAVGAMAAFLILSFYSVVAGWVLYYVGVMGADLLGAIAAGEPFRGALAGESQEAIQGRMG
NLFASPGLLLAMHLVFMGGTLFIVARGIGSGIEKAATWLMPAFFVLLVGITIYGAFVGDMGDAIAFLFTPDWSKLTPAVM
NSALGQALFSLSLGVAGLITYGSYINEGSKLGSTSATIAIADTSVALLAGLMIFPIVFAVGLDPAAGPTLVFQTLPFAFQ
SMPAGALIGFLFFVLILVAAITSSISLLEVPTAYGIGERGWSRRQSALIFGGGAFVVGIACLLGYNVWADVRLLGFWPLF
AETDILDTIDGFTGKVMLPLGALLTSVFIGWKADRKMVQEVTGLEGPMFAIWRFLIAWLCPLAVTIILITGLFPAVLGS

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI188528618, Length=376, Percent_Identity=27.1276595744681, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI4507043, Length=429, Percent_Identity=24.009324009324, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI92859670, Length=407, Percent_Identity=24.0786240786241, Blast_Score=96, Evalue=6e-20,
Organism=Homo sapiens, GI58219014, Length=310, Percent_Identity=27.4193548387097, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI21361581, Length=390, Percent_Identity=23.5897435897436, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI194018524, Length=312, Percent_Identity=27.5641025641026, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI33354281, Length=316, Percent_Identity=24.3670886075949, Blast_Score=88, Evalue=2e-17,
Organism=Homo sapiens, GI67782317, Length=371, Percent_Identity=25.3369272237197, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI11181770, Length=314, Percent_Identity=25.1592356687898, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI51468073, Length=321, Percent_Identity=22.7414330218069, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI171184408, Length=382, Percent_Identity=23.8219895287958, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI171184406, Length=382, Percent_Identity=23.8219895287958, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI171184404, Length=382, Percent_Identity=23.8219895287958, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI134304856, Length=414, Percent_Identity=27.0531400966184, Blast_Score=83, Evalue=5e-16,
Organism=Homo sapiens, GI5032097, Length=358, Percent_Identity=23.1843575418994, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI21361693, Length=124, Percent_Identity=30.6451612903226, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI197276623, Length=365, Percent_Identity=25.4794520547945, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI54607094, Length=365, Percent_Identity=25.4794520547945, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI4507041, Length=384, Percent_Identity=24.21875, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI289191351, Length=537, Percent_Identity=23.2774674115456, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI4557046, Length=537, Percent_Identity=23.2774674115456, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI289191377, Length=537, Percent_Identity=23.2774674115456, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI12408638, Length=290, Percent_Identity=25.1724137931034, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI218563756, Length=360, Percent_Identity=23.3333333333333, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI197276625, Length=127, Percent_Identity=33.0708661417323, Blast_Score=70, Evalue=6e-12,
Organism=Homo sapiens, GI6005715, Length=209, Percent_Identity=24.8803827751196, Blast_Score=67, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI71995588, Length=387, Percent_Identity=24.031007751938, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17555248, Length=394, Percent_Identity=23.8578680203046, Blast_Score=96, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI25146584, Length=435, Percent_Identity=23.2183908045977, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17542050, Length=132, Percent_Identity=37.1212121212121, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17554804, Length=503, Percent_Identity=23.8568588469185, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI115534083, Length=531, Percent_Identity=22.0338983050847, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17535731, Length=122, Percent_Identity=38.5245901639344, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI133952791, Length=122, Percent_Identity=35.2459016393443, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24661428, Length=389, Percent_Identity=26.7352185089974, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI17136952, Length=407, Percent_Identity=24.0786240786241, Blast_Score=108, Evalue=6e-24,
Organism=Drosophila melanogaster, GI281364394, Length=411, Percent_Identity=23.3576642335766, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28574704, Length=411, Percent_Identity=23.3576642335766, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI17136950, Length=411, Percent_Identity=23.3576642335766, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI28574702, Length=411, Percent_Identity=23.3576642335766, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI45550877, Length=434, Percent_Identity=26.2672811059908, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI45551183, Length=434, Percent_Identity=27.1889400921659, Blast_Score=103, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24639514, Length=531, Percent_Identity=23.5404896421846, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI221329674, Length=531, Percent_Identity=23.5404896421846, Blast_Score=100, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24639516, Length=306, Percent_Identity=27.1241830065359, Blast_Score=99, Evalue=9e-21,
Organism=Drosophila melanogaster, GI19921936, Length=381, Percent_Identity=27.0341207349081, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI19921352, Length=435, Percent_Identity=25.5172413793103, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24584353, Length=435, Percent_Identity=25.5172413793103, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI45551088, Length=382, Percent_Identity=24.869109947644, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24652942, Length=382, Percent_Identity=25.130890052356, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24762620, Length=382, Percent_Identity=24.869109947644, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24639853, Length=442, Percent_Identity=27.1493212669683, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI281365034, Length=446, Percent_Identity=26.0089686098655, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24582567, Length=397, Percent_Identity=25.1889168765743, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24655079, Length=321, Percent_Identity=28.3489096573209, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24654186, Length=413, Percent_Identity=23.9709443099274, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49811; Mature: 49811

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVASASTGSAARDGWSSRSAFILAAIGAAVGLGNIWRFPTLAGESGGGAFVFFYIACVFL
CCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHHH
LGLPLVLSEVFIGRAGQTDAVGSIKKVARDSGASESWSIFGAVGAMAAFLILSFYSVVAG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WVLYYVGVMGADLLGAIAAGEPFRGALAGESQEAIQGRMGNLFASPGLLLAMHLVFMGGT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCH
LFIVARGIGSGIEKAATWLMPAFFVLLVGITIYGAFVGDMGDAIAFLFTPDWSKLTPAVM
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHH
NSALGQALFSLSLGVAGLITYGSYINEGSKLGSTSATIAIADTSVALLAGLMIFPIVFAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHH
GLDPAAGPTLVFQTLPFAFQSMPAGALIGFLFFVLILVAAITSSISLLEVPTAYGIGERG
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCC
WSRRQSALIFGGGAFVVGIACLLGYNVWADVRLLGFWPLFAETDILDTIDGFTGKVMLPL
HHHCCCEEEECCHHHHHHHHHHHCCCHHHHHHHHEEEHHHHCCHHHHHHCCCCCHHHHHH
GALLTSVFIGWKADRKMVQEVTGLEGPMFAIWRFLIAWLCPLAVTIILITGLFPAVLGS
HHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVASASTGSAARDGWSSRSAFILAAIGAAVGLGNIWRFPTLAGESGGGAFVFFYIACVFL
CCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHHH
LGLPLVLSEVFIGRAGQTDAVGSIKKVARDSGASESWSIFGAVGAMAAFLILSFYSVVAG
HHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
WVLYYVGVMGADLLGAIAAGEPFRGALAGESQEAIQGRMGNLFASPGLLLAMHLVFMGGT
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCH
LFIVARGIGSGIEKAATWLMPAFFVLLVGITIYGAFVGDMGDAIAFLFTPDWSKLTPAVM
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHCCHHHH
NSALGQALFSLSLGVAGLITYGSYINEGSKLGSTSATIAIADTSVALLAGLMIFPIVFAV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHH
GLDPAAGPTLVFQTLPFAFQSMPAGALIGFLFFVLILVAAITSSISLLEVPTAYGIGERG
CCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHEECCCCCCCCCCC
WSRRQSALIFGGGAFVVGIACLLGYNVWADVRLLGFWPLFAETDILDTIDGFTGKVMLPL
HHHCCCEEEECCHHHHHHHHHHHCCCHHHHHHHHEEEHHHHCCHHHHHHCCCCCHHHHHH
GALLTSVFIGWKADRKMVQEVTGLEGPMFAIWRFLIAWLCPLAVTIILITGLFPAVLGS
HHHHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]