Click here to switch to the map view.

The map label for this gene is gutA [H]

Identifier: 85373863

GI number: 85373863

Start: 1073375

End: 1074730

Strand: Reverse

Name: gutA [H]

Synonym: ELI_05180

Alternate gene names: 85373863

Gene position: 1074730-1073375 (Counterclockwise)

Preceding gene: 85373864

Following gene: 85373861

Centisome position: 35.21

GC content: 60.32

Gene sequence:

>1356_bases
GTGAAAGACGGCGGGTTCAACTATTTCCTGCTGCTGTTCTACGGCACTGTCGTTGGGCTCGAACCGGGGCTGGTCGGCCT
TGCCATCCTGATCGCCCTCGTGCTCGATGCCGTGTCCGATCCGCTGGTCGGCTATTGGTCGGACAATTTCCGCTCGCGCT
GGGGCAGGCGCCACCCCTTCATGTATGCCGCCGCCATTCCGGTTGCGGCGAGCTATTACATGCTGTGGAACCCGCCCGAC
TGGAGTCAGGGCGCGCTGTTTGCCTACCTGCTCGGGCTCGCCGTGTTGATCCGCACCTTTATCACCTTCTACGAGACGCC
CAGTTCCGCACTACTTCCCGAGCTCTCGTCGGACTACGAAGAGCGCACCAGCCTGCAGACCTATCGCCTCTTCTTCGGCT
GGACCGGCGGCAATGCGATGACTGTGCTGATGTTCGGCGCACTGCTGGTGCCTACCGCAGTCTATTCGCACGGCATACTC
AACCGCGAAGGCTATGCGACCTATGGTGTGATCGCTTCGGTGCTGATCTTCGCCGCCATCATGATCTCGGCTCTCGGCAC
CCATCGCAACATACCGCAGTTGCGCGAGGCACCGGTCAATACCGAACGGTTTTCGCTGCGCAAACTGTTCGGCGAAATGT
TCGAGACGCTGAGCGAGAAGAGCTTCTTCGCGCTGTTCGTGGCCACGCTGCTTGGTTCGGTCGCCACGGGCGTGGCGGCC
TCGCTGGCCTTCATCATGCTGACCTATTTCTGGGGCTTTTCCACCCAGCAGCAATTCATCTGGACCGCGCTGGTGTTCTT
TTCGGCGCTGATAAGTTTCTTCGTCGCACCCTTCGCCGTCAAACGCGCGGGCAAGCGCAGAGCCGTTATCATCCTAGGGC
TGATCGCTTTCACCGTTGCGCCAGCGCCCGTGCTTCTCCGGCTGTTCGGTCTCATGCCGGAAAATGGCGATCCGATGCTG
TTTCCGCTGATCGCGACCATCAACACGCTGGACTTGTCACTGATTATCGCGCTGCAGGCGGTGCTCTATTCCATGATCGC
CGATCTCGTGGAGAGCAGCGAGCTAAGGACCGGGCGCCGCTCGGAGGGCGTGTTCTATGCCGCAGTCACCTTCACCCGCA
AATGCACGGTTGGCCTCGGATCCTTTGTCGGTGGCATCATCCTGTCGATCGTTGCCATACCCAAGGCAGCGGATCCCAGC
GATGTCACGCCCGACAAGTTATGGCTGCTCGGCGCATTCTATGCCCCTACCCTGCTCGCGCTGTGGATGGGCATGATCTA
CGCGATCAGCCGCTACAAGATCAGCAAGGAAGAGCACGAGGAAAACCTGCGCAAGCTCTCCTCGCAAGGCACCTGA

Upstream 100 bases:

>100_bases
AAAGCTGGCCACGCAAACCGACGCTCCGCTCGCACACGGCGCTGACAAGCCGCCGATCGCGACCAAGCTCGCCTATGGCT
TCGGCTCCGTCGCCTTTGGC

Downstream 100 bases:

>100_bases
TCAGGCGGGTACGCTTTCCTTCTGCATCGCATTCATGCGCGCGAGGATATCTTCCGCCTCCCGCATGGTGCGGTCGATCA
GTTCCTGACATGTCGGGATA

Product: sugar transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MKDGGFNYFLLLFYGTVVGLEPGLVGLAILIALVLDAVSDPLVGYWSDNFRSRWGRRHPFMYAAAIPVAASYYMLWNPPD
WSQGALFAYLLGLAVLIRTFITFYETPSSALLPELSSDYEERTSLQTYRLFFGWTGGNAMTVLMFGALLVPTAVYSHGIL
NREGYATYGVIASVLIFAAIMISALGTHRNIPQLREAPVNTERFSLRKLFGEMFETLSEKSFFALFVATLLGSVATGVAA
SLAFIMLTYFWGFSTQQQFIWTALVFFSALISFFVAPFAVKRAGKRRAVIILGLIAFTVAPAPVLLRLFGLMPENGDPML
FPLIATINTLDLSLIIALQAVLYSMIADLVESSELRTGRRSEGVFYAAVTFTRKCTVGLGSFVGGIILSIVAIPKAADPS
DVTPDKLWLLGAFYAPTLLALWMGMIYAISRYKISKEEHEENLRKLSSQGT

Sequences:

>Translated_451_residues
MKDGGFNYFLLLFYGTVVGLEPGLVGLAILIALVLDAVSDPLVGYWSDNFRSRWGRRHPFMYAAAIPVAASYYMLWNPPD
WSQGALFAYLLGLAVLIRTFITFYETPSSALLPELSSDYEERTSLQTYRLFFGWTGGNAMTVLMFGALLVPTAVYSHGIL
NREGYATYGVIASVLIFAAIMISALGTHRNIPQLREAPVNTERFSLRKLFGEMFETLSEKSFFALFVATLLGSVATGVAA
SLAFIMLTYFWGFSTQQQFIWTALVFFSALISFFVAPFAVKRAGKRRAVIILGLIAFTVAPAPVLLRLFGLMPENGDPML
FPLIATINTLDLSLIIALQAVLYSMIADLVESSELRTGRRSEGVFYAAVTFTRKCTVGLGSFVGGIILSIVAIPKAADPS
DVTPDKLWLLGAFYAPTLLALWMGMIYAISRYKISKEEHEENLRKLSSQGT
>Mature_451_residues
MKDGGFNYFLLLFYGTVVGLEPGLVGLAILIALVLDAVSDPLVGYWSDNFRSRWGRRHPFMYAAAIPVAASYYMLWNPPD
WSQGALFAYLLGLAVLIRTFITFYETPSSALLPELSSDYEERTSLQTYRLFFGWTGGNAMTVLMFGALLVPTAVYSHGIL
NREGYATYGVIASVLIFAAIMISALGTHRNIPQLREAPVNTERFSLRKLFGEMFETLSEKSFFALFVATLLGSVATGVAA
SLAFIMLTYFWGFSTQQQFIWTALVFFSALISFFVAPFAVKRAGKRRAVIILGLIAFTVAPAPVLLRLFGLMPENGDPML
FPLIATINTLDLSLIIALQAVLYSMIADLVESSELRTGRRSEGVFYAAVTFTRKCTVGLGSFVGGIILSIVAIPKAADPS
DVTPDKLWLLGAFYAPTLLALWMGMIYAISRYKISKEEHEENLRKLSSQGT

Specific function: Probably involved in glucitol uptake [H]

COG id: COG2211

COG function: function code G; Na+/melibiose symporter and related transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:galactoside symporter (TC 2.A.2) family [H]

Homologues:

Organism=Homo sapiens, GI42713696, Length=411, Percent_Identity=24.5742092457421, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1786466, Length=444, Percent_Identity=25, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI87082306, Length=381, Percent_Identity=24.6719160104987, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI48994989, Length=466, Percent_Identity=24.0343347639485, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790561, Length=394, Percent_Identity=20.3045685279188, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI145693206, Length=462, Percent_Identity=25.3246753246753, Blast_Score=72, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001927
- InterPro:   IPR018043 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 49710; Mature: 49710

Theoretical pI: Translated: 8.71; Mature: 8.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDGGFNYFLLLFYGTVVGLEPGLVGLAILIALVLDAVSDPLVGYWSDNFRSRWGRRHPF
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCCHHHHHHCCCCCCC
MYAAAIPVAASYYMLWNPPDWSQGALFAYLLGLAVLIRTFITFYETPSSALLPELSSDYE
HHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCHH
ERTSLQTYRLFFGWTGGNAMTVLMFGALLVPTAVYSHGILNREGYATYGVIASVLIFAAI
HHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
MISALGTHRNIPQLREAPVNTERFSLRKLFGEMFETLSEKSFFALFVATLLGSVATGVAA
HHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAFIMLTYFWGFSTQQQFIWTALVFFSALISFFVAPFAVKRAGKRRAVIILGLIAFTVA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
PAPVLLRLFGLMPENGDPMLFPLIATINTLDLSLIIALQAVLYSMIADLVESSELRTGRR
CHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SEGVFYAAVTFTRKCTVGLGSFVGGIILSIVAIPKAADPSDVTPDKLWLLGAFYAPTLLA
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LWMGMIYAISRYKISKEEHEENLRKLSSQGT
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKDGGFNYFLLLFYGTVVGLEPGLVGLAILIALVLDAVSDPLVGYWSDNFRSRWGRRHPF
CCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEECCCHHHHHHCCCCCCC
MYAAAIPVAASYYMLWNPPDWSQGALFAYLLGLAVLIRTFITFYETPSSALLPELSSDYE
HHHHHHHHHHCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHCCHH
ERTSLQTYRLFFGWTGGNAMTVLMFGALLVPTAVYSHGILNREGYATYGVIASVLIFAAI
HHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHH
MISALGTHRNIPQLREAPVNTERFSLRKLFGEMFETLSEKSFFALFVATLLGSVATGVAA
HHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLAFIMLTYFWGFSTQQQFIWTALVFFSALISFFVAPFAVKRAGKRRAVIILGLIAFTVA
HHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHC
PAPVLLRLFGLMPENGDPMLFPLIATINTLDLSLIIALQAVLYSMIADLVESSELRTGRR
CHHHHHHHHHCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SEGVFYAAVTFTRKCTVGLGSFVGGIILSIVAIPKAADPSDVTPDKLWLLGAFYAPTLLA
CCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHH
LWMGMIYAISRYKISKEEHEENLRKLSSQGT
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9455482; 9384377 [H]