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The map label for this gene is suhB [H]

Identifier: 85373843

GI number: 85373843

Start: 1048534

End: 1049346

Strand: Reverse

Name: suhB [H]

Synonym: ELI_05080

Alternate gene names: 85373843

Gene position: 1049346-1048534 (Counterclockwise)

Preceding gene: 85373844

Following gene: 85373834

Centisome position: 34.38

GC content: 63.1

Gene sequence:

>813_bases
TTGAGTGCGCTCGACGACGAATTGCTCGACCTGTTTCGGTTCGCTGCCGAACGCTCGATCCTGCCGCGCTGGCAGAACCT
GCGCAGCGACCAGATCGAGGAAAAGGCCAAGGGCGATCTCGTGACGGTGGTCGATCAAGAAGTCGAAGAGTTTCTCAGCG
AAGCGCTCACGAAGTTACAGCCCGGCGTTGCCATCGTGGGAGAGGAAGCGGCGCATTCCGATCCGTCGGTGCTCGAACAG
CTTTCAGGCCCCTGCTGGATCATCGACCCCATCGACGGCACGAGCAATTTCGCGCGCGGCGAAGGCCATTTCGCAATCAT
GCTCGCGCTGGCCGACGGCGGTGAGACGATTGCGAGCTGGATATACGATCCCGTCCGTCCTCGCCTGCTAACAGCGCGCA
AGGGTGGCGGAGCGTTCCGCGACGGGGATCCGGTGAAAGCGTCTTCAGATGGAGAGACCCCACCGACTCTGTCGGCGATG
ACAAAATTTATGAATGACGAGCAACGCGCTCTGTTCGTGGCAGAGATCGTGCCTCACTACACTCTGGCCACAGCCCCAGG
CGCAGCGGCGGAAGAATACCCGCGCGTCGCCTTCGGGGGCACCGACATCGCGATCTATGAGCGCACGCTGCCATGGGATC
ATGCCGCCGGGTGCCTGTTCCTCAACGAGGCAGGCGGAGTGTGCGCACGGCAGGACGGATCGCCCTATCGGGTCGACTCG
GATCGCAAAGGGATGATTGCCGCCGCCAGCCAGGGCTTGTGGGACGAATTCGTCGCGCGGCTCGAGACCTTGGGCTTCCG
CCCGGGCGGCTAG

Upstream 100 bases:

>100_bases
TCAGCGTCGAAGTCGATCTAGGCATCGGCGATGGCAAAGCGACCGTGTGGACCTGCGACCTTACGCATGGCTACATCGCC
ATCAACGCCGACTACCGATC

Downstream 100 bases:

>100_bases
ATCACCCGGGTCAGAAACCGCACCGGATCAGATTTCGCTTTCGATCCAGTCCTTGAGCTGGCTCTTGGGCGCAGCGCCGA
CCTTGCGGGCGACCGCTTCG

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MSALDDELLDLFRFAAERSILPRWQNLRSDQIEEKAKGDLVTVVDQEVEEFLSEALTKLQPGVAIVGEEAAHSDPSVLEQ
LSGPCWIIDPIDGTSNFARGEGHFAIMLALADGGETIASWIYDPVRPRLLTARKGGGAFRDGDPVKASSDGETPPTLSAM
TKFMNDEQRALFVAEIVPHYTLATAPGAAAEEYPRVAFGGTDIAIYERTLPWDHAAGCLFLNEAGGVCARQDGSPYRVDS
DRKGMIAAASQGLWDEFVARLETLGFRPGG

Sequences:

>Translated_270_residues
MSALDDELLDLFRFAAERSILPRWQNLRSDQIEEKAKGDLVTVVDQEVEEFLSEALTKLQPGVAIVGEEAAHSDPSVLEQ
LSGPCWIIDPIDGTSNFARGEGHFAIMLALADGGETIASWIYDPVRPRLLTARKGGGAFRDGDPVKASSDGETPPTLSAM
TKFMNDEQRALFVAEIVPHYTLATAPGAAAEEYPRVAFGGTDIAIYERTLPWDHAAGCLFLNEAGGVCARQDGSPYRVDS
DRKGMIAAASQGLWDEFVARLETLGFRPGG
>Mature_269_residues
SALDDELLDLFRFAAERSILPRWQNLRSDQIEEKAKGDLVTVVDQEVEEFLSEALTKLQPGVAIVGEEAAHSDPSVLEQL
SGPCWIIDPIDGTSNFARGEGHFAIMLALADGGETIASWIYDPVRPRLLTARKGGGAFRDGDPVKASSDGETPPTLSAMT
KFMNDEQRALFVAEIVPHYTLATAPGAAAEEYPRVAFGGTDIAIYERTLPWDHAAGCLFLNEAGGVCARQDGSPYRVDSD
RKGMIAAASQGLWDEFVARLETLGFRPGG

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI5031789, Length=238, Percent_Identity=30.672268907563, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI221625487, Length=238, Percent_Identity=30.672268907563, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI7657236, Length=264, Percent_Identity=28.4090909090909, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI221625507, Length=113, Percent_Identity=37.1681415929204, Blast_Score=75, Evalue=5e-14,
Organism=Escherichia coli, GI1788882, Length=210, Percent_Identity=33.8095238095238, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1790659, Length=208, Percent_Identity=25.4807692307692, Blast_Score=61, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI193202572, Length=246, Percent_Identity=31.7073170731707, Blast_Score=101, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI193202570, Length=249, Percent_Identity=30.9236947791165, Blast_Score=98, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6320493, Length=231, Percent_Identity=29.8701298701299, Blast_Score=90, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24664918, Length=264, Percent_Identity=29.9242424242424, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI21357957, Length=225, Percent_Identity=31.5555555555556, Blast_Score=110, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24664922, Length=232, Percent_Identity=31.8965517241379, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24664926, Length=249, Percent_Identity=30.1204819277108, Blast_Score=107, Evalue=7e-24,
Organism=Drosophila melanogaster, GI21357329, Length=245, Percent_Identity=31.4285714285714, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI21357303, Length=206, Percent_Identity=32.5242718446602, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29198; Mature: 29067

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS00629 IMP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALDDELLDLFRFAAERSILPRWQNLRSDQIEEKAKGDLVTVVDQEVEEFLSEALTKLQ
CCCCHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHC
PGVAIVGEEAAHSDPSVLEQLSGPCWIIDPIDGTSNFARGEGHFAIMLALADGGETIASW
CCEEEEECCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHH
IYDPVRPRLLTARKGGGAFRDGDPVKASSDGETPPTLSAMTKFMNDEQRALFVAEIVPHY
HHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCC
TLATAPGAAAEEYPRVAFGGTDIAIYERTLPWDHAAGCLFLNEAGGVCARQDGSPYRVDS
EEECCCCCCHHHCCCEEECCCEEEEEEECCCCCCCCCEEEEECCCCEEECCCCCCCEECC
DRKGMIAAASQGLWDEFVARLETLGFRPGG
CCCCEEEHHCCCHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SALDDELLDLFRFAAERSILPRWQNLRSDQIEEKAKGDLVTVVDQEVEEFLSEALTKLQ
CCCHHHHHHHHHHHHHHHHCHHHHHCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHC
PGVAIVGEEAAHSDPSVLEQLSGPCWIIDPIDGTSNFARGEGHFAIMLALADGGETIASW
CCEEEEECCCCCCCHHHHHHHCCCEEEEECCCCCCCCCCCCCCEEEEEEECCCCHHHHHH
IYDPVRPRLLTARKGGGAFRDGDPVKASSDGETPPTLSAMTKFMNDEQRALFVAEIVPHY
HHCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCHHHHHHHHHHHCCC
TLATAPGAAAEEYPRVAFGGTDIAIYERTLPWDHAAGCLFLNEAGGVCARQDGSPYRVDS
EEECCCCCCHHHCCCEEECCCEEEEEEECCCCCCCCCEEEEECCCCEEECCCCCCCEECC
DRKGMIAAASQGLWDEFVARLETLGFRPGG
CCCCEEEHHCCCHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969500; 9384377 [H]