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The map label for this gene is hipA [C]

Identifier: 85373671

GI number: 85373671

Start: 872193

End: 873407

Strand: Reverse

Name: hipA [C]

Synonym: ELI_04220

Alternate gene names: 85373671

Gene position: 873407-872193 (Counterclockwise)

Preceding gene: 85373672

Following gene: 85373664

Centisome position: 28.61

GC content: 59.67

Gene sequence:

>1215_bases
ATGATCAACGCAGCGGCTCTCGATATCTTTCTGGGTGAGACGCGCGTTGGAACCATCGCACGGCTCGATGGAGATGCGAG
CATCTTCACATTCGACGATGTCTACCTTGCCGACCAGGATCGGCCGACGCTTTCGCTCGCCTACAAGGACGCGAATGGCG
AGATCATCGCAGAGCCACGTAGCTATCGAACGAAGATCGAGCCGTTCTTCTCCAACCTCCTTCCTGAAGGAACGCTTCGC
GACTACCTGGCCCGCCGCGCCGGCGTGAAAGCCGTGCGCGAATACCACCTTCTCGCACAGCTCGGGCACGATCTTCCCGG
CGCAGTGCGCGCCCTCGCCGTCGATGCCGAGGAAACGGAGGCCGACGAGCTAGATGAAGAAGCGGCGGGGAAGCAGGCAG
AGCGCGCGCTGCGCTTCTCGCTTGCCGGCGTGCAACTCAAATTCTCGGCTATCAAAGCCCAGGGCAAGAATGGCGGACTG
ACGATCCCAGTCACAGGCAGCGGCGGCGACTGGATCGTCAAGCTGCCCTCTGCGAGACATCCGGACGTGCCCGAGGCTGA
ATTCGCAGCGATGAAACTGGCAGCAAAGATCGGGATCGACGTACCTGAAATCGGCCTTGTGCCTCTCGATCAGATCGATG
GCATACCCGAAGGTATCACCCGTTACGGAGAGTCCGCTTTTGCCATCCGGCGCTTCGACCGGGGGGAAGAGGGACCCGTG
CACACCGAAGACTTCGCCCAGGTGTTCGGTGTCTTTGCAGACGATAAATACGAGAATGCGAGCTACCGCCAGATTCTCAG
TGTCCTGGCGATCGAGACCGACGAACAAAGCGTGGTCGAATTCGTCCGCCGGCTCACCTACTCGGTACTGATCGGGAATG
GCGACATGCACCTCAAGAACTGGTCGTTGATCTACCCGGATAGGCGTAACGCGCTGCTGGCACCTGCCTATGACCTGCTT
TCGACGCTCGACTATATCCCAGGCGACGATGCTGCACTCAAGTTTCATAGCTCGCGCGAGTGGGCATCCTACACCTATGA
TGAACTCGAGGCGATCGCCGACAAGGCGAAGCTGCCTGCCAAGCTGATCACCGCGACAGCGAAGGATGTCGTTGCACGGT
TCGACGACGCCTGGCGCAGCGAAAGCGGACACCTGCCCTTCCCCGATGATGTACGAAGCGCGATTGAGAGGCATCGCAAA
ACTCTTGCGATCTGA

Upstream 100 bases:

>100_bases
CCACACGTGCCCTACGGCACGTCAGAAACCTGCAGGTTCACTCAATCGATCGAGATAGTGCCCACAGACTGCCTGCTTAC
CGGCTTGAGGACGACGCCAC

Downstream 100 bases:

>100_bases
GAGCTGCTCCGAAATCTGGTCGTGCACGCGCAGGCACGACCCGGAACAACTGCCGGGGCCAATTCGTCAGAAAATCTGGC
ACATAGCGGCCCTTCAAATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MINAAALDIFLGETRVGTIARLDGDASIFTFDDVYLADQDRPTLSLAYKDANGEIIAEPRSYRTKIEPFFSNLLPEGTLR
DYLARRAGVKAVREYHLLAQLGHDLPGAVRALAVDAEETEADELDEEAAGKQAERALRFSLAGVQLKFSAIKAQGKNGGL
TIPVTGSGGDWIVKLPSARHPDVPEAEFAAMKLAAKIGIDVPEIGLVPLDQIDGIPEGITRYGESAFAIRRFDRGEEGPV
HTEDFAQVFGVFADDKYENASYRQILSVLAIETDEQSVVEFVRRLTYSVLIGNGDMHLKNWSLIYPDRRNALLAPAYDLL
STLDYIPGDDAALKFHSSREWASYTYDELEAIADKAKLPAKLITATAKDVVARFDDAWRSESGHLPFPDDVRSAIERHRK
TLAI

Sequences:

>Translated_404_residues
MINAAALDIFLGETRVGTIARLDGDASIFTFDDVYLADQDRPTLSLAYKDANGEIIAEPRSYRTKIEPFFSNLLPEGTLR
DYLARRAGVKAVREYHLLAQLGHDLPGAVRALAVDAEETEADELDEEAAGKQAERALRFSLAGVQLKFSAIKAQGKNGGL
TIPVTGSGGDWIVKLPSARHPDVPEAEFAAMKLAAKIGIDVPEIGLVPLDQIDGIPEGITRYGESAFAIRRFDRGEEGPV
HTEDFAQVFGVFADDKYENASYRQILSVLAIETDEQSVVEFVRRLTYSVLIGNGDMHLKNWSLIYPDRRNALLAPAYDLL
STLDYIPGDDAALKFHSSREWASYTYDELEAIADKAKLPAKLITATAKDVVARFDDAWRSESGHLPFPDDVRSAIERHRK
TLAI
>Mature_404_residues
MINAAALDIFLGETRVGTIARLDGDASIFTFDDVYLADQDRPTLSLAYKDANGEIIAEPRSYRTKIEPFFSNLLPEGTLR
DYLARRAGVKAVREYHLLAQLGHDLPGAVRALAVDAEETEADELDEEAAGKQAERALRFSLAGVQLKFSAIKAQGKNGGL
TIPVTGSGGDWIVKLPSARHPDVPEAEFAAMKLAAKIGIDVPEIGLVPLDQIDGIPEGITRYGESAFAIRRFDRGEEGPV
HTEDFAQVFGVFADDKYENASYRQILSVLAIETDEQSVVEFVRRLTYSVLIGNGDMHLKNWSLIYPDRRNALLAPAYDLL
STLDYIPGDDAALKFHSSREWASYTYDELEAIADKAKLPAKLITATAKDVVARFDDAWRSESGHLPFPDDVRSAIERHRK
TLAI

Specific function: Unbalanced Or Excessive Expression Of Hipa Is Toxic To The Cell. [C]

COG id: COG3550

COG function: function code R; Uncharacterized protein related to capsule biosynthesis enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli hipA, H.influenzae HI_0665 and y4mE [H]

Homologues:

Organism=Escherichia coli, GI1787785, Length=362, Percent_Identity=24.8618784530387, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012893
- InterPro:   IPR012894
- InterPro:   IPR017508 [H]

Pfam domain/function: PF07804 HipA_C; PF07805 HipA_N [H]

EC number: NA

Molecular weight: Translated: 44524; Mature: 44524

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
0.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINAAALDIFLGETRVGTIARLDGDASIFTFDDVYLADQDRPTLSLAYKDANGEIIAEPR
CCCCEEEEEEECCCCCCEEEEECCCCEEEEECCEEEECCCCCEEEEEEECCCCCEEECCH
SYRTKIEPFFSNLLPEGTLRDYLARRAGVKAVREYHLLAQLGHDLPGAVRALAVDAEETE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEECCCCCC
ADELDEEAAGKQAERALRFSLAGVQLKFSAIKAQGKNGGLTIPVTGSGGDWIVKLPSARH
HHHHHHHHCCHHHHHHHHHHHCCEEEEEEEEEECCCCCCEEEEEECCCCCEEEECCCCCC
PDVPEAEFAAMKLAAKIGIDVPEIGLVPLDQIDGIPEGITRYGESAFAIRRFDRGEEGPV
CCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHCCCHHHHHHHCCHHHHHHHCCCCCCCCC
HTEDFAQVFGVFADDKYENASYRQILSVLAIETDEQSVVEFVRRLTYSVLIGNGDMHLKN
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCEEEEC
WSLIYPDRRNALLAPAYDLLSTLDYIPGDDAALKFHSSREWASYTYDELEAIADKAKLPA
CEEECCCCCCEEECHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCHHHHHHHHHHHHCCH
KLITATAKDVVARFDDAWRSESGHLPFPDDVRSAIERHRKTLAI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MINAAALDIFLGETRVGTIARLDGDASIFTFDDVYLADQDRPTLSLAYKDANGEIIAEPR
CCCCEEEEEEECCCCCCEEEEECCCCEEEEECCEEEECCCCCEEEEEEECCCCCEEECCH
SYRTKIEPFFSNLLPEGTLRDYLARRAGVKAVREYHLLAQLGHDLPGAVRALAVDAEETE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEEECCCCCC
ADELDEEAAGKQAERALRFSLAGVQLKFSAIKAQGKNGGLTIPVTGSGGDWIVKLPSARH
HHHHHHHHCCHHHHHHHHHHHCCEEEEEEEEEECCCCCCEEEEEECCCCCEEEECCCCCC
PDVPEAEFAAMKLAAKIGIDVPEIGLVPLDQIDGIPEGITRYGESAFAIRRFDRGEEGPV
CCCCCHHHHHHHHHHHHCCCCCCCCCEEHHHHCCCHHHHHHHCCHHHHHHHCCCCCCCCC
HTEDFAQVFGVFADDKYENASYRQILSVLAIETDEQSVVEFVRRLTYSVLIGNGDMHLKN
CHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHEEEEECCCCEEEEC
WSLIYPDRRNALLAPAYDLLSTLDYIPGDDAALKFHSSREWASYTYDELEAIADKAKLPA
CEEECCCCCCEEECHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCHHHHHHHHHHHHCCH
KLITATAKDVVARFDDAWRSESGHLPFPDDVRSAIERHRKTLAI
HHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]