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The map label for this gene is 85373652

Identifier: 85373652

GI number: 85373652

Start: 851129

End: 853648

Strand: Reverse

Name: 85373652

Synonym: ELI_04125

Alternate gene names: NA

Gene position: 853648-851129 (Counterclockwise)

Preceding gene: 85373653

Following gene: 85373648

Centisome position: 27.97

GC content: 63.57

Gene sequence:

>2520_bases
ATGGCGCGCCGGAATGACCCGCTCGCCATATACAATTCCAAGCGCGATTTCGCAAAAACGCCCGAACCCTCCGGCAAGGC
GGAAAGCAGTGCGGGCGGCGACCTCTTCATAGTCCAGAAGCACGACGCCACGCGGCTGCACTGGGACTTGCGACTGGAAG
TGGATGGCGTGCTGAAAAGCTGGGCGGTCACCAAGGGGCCCTCTCCCGATCCGGACATCAAGCGCCTGGCCGTGCGGACG
GAAGACCACCCGGTGTCCTACGCCGAATTCGAAGGGACCATCCCGAAGGGCGAGTACGGCGGCGGCACGGTAATGCTGTG
GGACCGTGGCAGCTGGGCCCCAATCGAGGGCAAGAGCGCGAAAGACCTGGAGAAGGGCCACCTCCATTTCATCCTGCAGG
GCGGGCGAATGCAGGGCGAGTGGTTGTTGATAAGGCTGAAGAAAAAGCCGGGAGAAAAGCGGGAGAACTGGCTCCTGCGC
AAATTGCAGGACGAGCATGCCGAAGAAGGCGACGTGCTGGTGGAGCGCGAGCTGACGAGCGTGCTGACCGGCCGCTCCAT
GGCGGAAATCGCCGCGGACAAGAAAGGCGAATACCCGCTGGCCGGCAAGAAGGACGAGGCTTTTCTGGCGCAAATGGAGA
AGGCCTCCGCCCGCAACGAGGCCAAGGCCAAGCAGAGAAAACGTCGCAAGGCAGCGCCCCTGCCGAAGTTTCGCCAACCG
CAGCTCGCGACCCTGGTCGACGACGTGCCCGCCGGAAACGGCTGGATGCACGAGATCAAGTTCGATGGATACCGCGCTCT
TGTCGCTGCGAAGGGCAATGACGTGCGTGTCTTTACCCGCAGCGGGAAGGACTGGACGGAGAAGTTCGGCCCGCTGGTAG
GAGCGATTGCCGCGCTGGACTTGCCCGCCAGCCTGATCGACGGCGAGATCGTGGCGAGCGATGCCGATGGCAATCCCGAT
TTCTCCAAGCTGCAGCAGGTCCTGAAGCGTGGCCACGGCAGCCAGTCCAAGGCCGACCGGCTGGCCTTCCACGCCTTCGA
CCTGGTCGAGCTGGATGGCGAGGATCTCGCCAAGCTGCCCAATATCGAGCGCAAGGAGCGGCTTGAGGCAATGCTCGCCA
CGGCCGAACCGCCGATCCACGTCGCCGACCATGTGATCGGCGCGGGCGAGAAGCTGTACGAGGCGATGTGCGCCGCCGGG
CAGGAAGGCATCATTTCCAAGAAAATCGACGCGCCCTATCGCCATTCGCGAAGCAAGGGCTGGGTAAAGGTCAAATGCAC
CCGGCGGCAAGAATTCGTGATCGTCGGCTGGAAGGCGTCCCGCGCCAAGGGCCGCCCATTCGCATCGCTGCTGATGGCGC
AGAACGAAGACGGCGAGCTGGTCTACAAGGGCAACGTCGGCACGGGCTTCACGGCCGACGAGCTGGACATGCTGGCCGGA
AAACTCAAACGGCTGGAGCGCAAGACGCCGCCGGTGGCGGTGGACGCAGCCAGCGCACGGCAAGTGACATGGGTGGCGCC
GAAGCTGGTAGCCGAAATCGCGTTCGCCGAATTCACCGCGGACGGCAAGATCCGGCACGGCAGTTATCTGGGCCTGCGGT
CGGACAAAGACGCGGACGATGTGAAGCCGGAAAAGGCGGCCCCCGCCCCTAAAACGGCAGCTAACGTCAAGATCTCCAGC
CGCGACCGCGTGGTATTCCCCGATAGCGGGCAGACCAAGGGCGAACTTGCGGACTATTACGAGGCCGTCGCGGGTATCAT
GCTGCCCTTCGCCGCGCGCCGTCCCGTCAGCCTCGTGCGCTGTCCACAGGGACGGGCCAAGAAATGCTTCTTCCAGAAAC
ACGATAGCGGCGCGTTCGGCGACGCGGTGCACCACGTGCCGATCATGGAGAAGGACGGCGGGACGAAGGGTTACCTCTAT
GTCGAGGATGCGCGCGGCATCCTGCAATGCGTGCAGATGGGCACGATCGAATTCCACGGCTGGGCCTCGCGCACCGACGA
TGTGGAATTGCCGGACCGGATGATCTTCGACCTCGACCCGGACGAGGGGCTGGACTTCGGCGACGTGAAGCAGGCGGCAC
GCGATATAAAGGCGCGGCTTTCCGATATCGGCCTCGTCAGCTTTGCGATGCTTTCGGGCGGGAAGGGCGTGCATGTCGTG
GTACCATTGGCGCCCGGCCATTCATGGGACGCGCACAAGGACTTCGCTCGCCGTTTTGCCGAGGCGCTGTCGCTGGCAGA
GCCGCAGCGCTTCACCGCCACGATGAGCAAGGCCAAGCGCAAAGGAAAGATCTTCATCGACTGGCTGCGCAACCAGCGCG
GCAGCACCGCGGTTCTACCTTACTCCGCACGCGCCCGTCGCGGCGCACCCGTGGCGGTGCCAATAGGCTGGAACGAATTG
AAGGATATGCAGAACGCCAAGTCCTTTAGCATTAACGACGCCAATCGCCTTCTCACACGAGCGGGCAGCAAGACGCTGGC
TGGATGGGGCTTTGCGGATCAAGAGCTGCCGGATCACTGA

Upstream 100 bases:

>100_bases
GGTGGCAATGTGATCGACCTGATGGCCGCGTTGAAGAAGTCGGTGGGTGAAAAGCCCGCGGCGAAGAAATCGGGGTCCAC
GCGCAAGAAGAGCGCGTGAC

Downstream 100 bases:

>100_bases
AACGATGGGCTAATCAAACGTCCGCAGCTCATCATCCCGGTCTTAAAAGCAGATAGTCCGCTCCCGGCCCCGAAGCTGCC
CATTGAGGTCTTTCGAATTA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 839; Mature: 838

Protein sequence:

>839_residues
MARRNDPLAIYNSKRDFAKTPEPSGKAESSAGGDLFIVQKHDATRLHWDLRLEVDGVLKSWAVTKGPSPDPDIKRLAVRT
EDHPVSYAEFEGTIPKGEYGGGTVMLWDRGSWAPIEGKSAKDLEKGHLHFILQGGRMQGEWLLIRLKKKPGEKRENWLLR
KLQDEHAEEGDVLVERELTSVLTGRSMAEIAADKKGEYPLAGKKDEAFLAQMEKASARNEAKAKQRKRRKAAPLPKFRQP
QLATLVDDVPAGNGWMHEIKFDGYRALVAAKGNDVRVFTRSGKDWTEKFGPLVGAIAALDLPASLIDGEIVASDADGNPD
FSKLQQVLKRGHGSQSKADRLAFHAFDLVELDGEDLAKLPNIERKERLEAMLATAEPPIHVADHVIGAGEKLYEAMCAAG
QEGIISKKIDAPYRHSRSKGWVKVKCTRRQEFVIVGWKASRAKGRPFASLLMAQNEDGELVYKGNVGTGFTADELDMLAG
KLKRLERKTPPVAVDAASARQVTWVAPKLVAEIAFAEFTADGKIRHGSYLGLRSDKDADDVKPEKAAPAPKTAANVKISS
RDRVVFPDSGQTKGELADYYEAVAGIMLPFAARRPVSLVRCPQGRAKKCFFQKHDSGAFGDAVHHVPIMEKDGGTKGYLY
VEDARGILQCVQMGTIEFHGWASRTDDVELPDRMIFDLDPDEGLDFGDVKQAARDIKARLSDIGLVSFAMLSGGKGVHVV
VPLAPGHSWDAHKDFARRFAEALSLAEPQRFTATMSKAKRKGKIFIDWLRNQRGSTAVLPYSARARRGAPVAVPIGWNEL
KDMQNAKSFSINDANRLLTRAGSKTLAGWGFADQELPDH

Sequences:

>Translated_839_residues
MARRNDPLAIYNSKRDFAKTPEPSGKAESSAGGDLFIVQKHDATRLHWDLRLEVDGVLKSWAVTKGPSPDPDIKRLAVRT
EDHPVSYAEFEGTIPKGEYGGGTVMLWDRGSWAPIEGKSAKDLEKGHLHFILQGGRMQGEWLLIRLKKKPGEKRENWLLR
KLQDEHAEEGDVLVERELTSVLTGRSMAEIAADKKGEYPLAGKKDEAFLAQMEKASARNEAKAKQRKRRKAAPLPKFRQP
QLATLVDDVPAGNGWMHEIKFDGYRALVAAKGNDVRVFTRSGKDWTEKFGPLVGAIAALDLPASLIDGEIVASDADGNPD
FSKLQQVLKRGHGSQSKADRLAFHAFDLVELDGEDLAKLPNIERKERLEAMLATAEPPIHVADHVIGAGEKLYEAMCAAG
QEGIISKKIDAPYRHSRSKGWVKVKCTRRQEFVIVGWKASRAKGRPFASLLMAQNEDGELVYKGNVGTGFTADELDMLAG
KLKRLERKTPPVAVDAASARQVTWVAPKLVAEIAFAEFTADGKIRHGSYLGLRSDKDADDVKPEKAAPAPKTAANVKISS
RDRVVFPDSGQTKGELADYYEAVAGIMLPFAARRPVSLVRCPQGRAKKCFFQKHDSGAFGDAVHHVPIMEKDGGTKGYLY
VEDARGILQCVQMGTIEFHGWASRTDDVELPDRMIFDLDPDEGLDFGDVKQAARDIKARLSDIGLVSFAMLSGGKGVHVV
VPLAPGHSWDAHKDFARRFAEALSLAEPQRFTATMSKAKRKGKIFIDWLRNQRGSTAVLPYSARARRGAPVAVPIGWNEL
KDMQNAKSFSINDANRLLTRAGSKTLAGWGFADQELPDH
>Mature_838_residues
ARRNDPLAIYNSKRDFAKTPEPSGKAESSAGGDLFIVQKHDATRLHWDLRLEVDGVLKSWAVTKGPSPDPDIKRLAVRTE
DHPVSYAEFEGTIPKGEYGGGTVMLWDRGSWAPIEGKSAKDLEKGHLHFILQGGRMQGEWLLIRLKKKPGEKRENWLLRK
LQDEHAEEGDVLVERELTSVLTGRSMAEIAADKKGEYPLAGKKDEAFLAQMEKASARNEAKAKQRKRRKAAPLPKFRQPQ
LATLVDDVPAGNGWMHEIKFDGYRALVAAKGNDVRVFTRSGKDWTEKFGPLVGAIAALDLPASLIDGEIVASDADGNPDF
SKLQQVLKRGHGSQSKADRLAFHAFDLVELDGEDLAKLPNIERKERLEAMLATAEPPIHVADHVIGAGEKLYEAMCAAGQ
EGIISKKIDAPYRHSRSKGWVKVKCTRRQEFVIVGWKASRAKGRPFASLLMAQNEDGELVYKGNVGTGFTADELDMLAGK
LKRLERKTPPVAVDAASARQVTWVAPKLVAEIAFAEFTADGKIRHGSYLGLRSDKDADDVKPEKAAPAPKTAANVKISSR
DRVVFPDSGQTKGELADYYEAVAGIMLPFAARRPVSLVRCPQGRAKKCFFQKHDSGAFGDAVHHVPIMEKDGGTKGYLYV
EDARGILQCVQMGTIEFHGWASRTDDVELPDRMIFDLDPDEGLDFGDVKQAARDIKARLSDIGLVSFAMLSGGKGVHVVV
PLAPGHSWDAHKDFARRFAEALSLAEPQRFTATMSKAKRKGKIFIDWLRNQRGSTAVLPYSARARRGAPVAVPIGWNELK
DMQNAKSFSINDANRLLTRAGSKTLAGWGFADQELPDH

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=291, Percent_Identity=27.4914089347079, Blast_Score=74, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 92346; Mature: 92215

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRNDPLAIYNSKRDFAKTPEPSGKAESSAGGDLFIVQKHDATRLHWDLRLEVDGVLKS
CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEEHHHHHH
WAVTKGPSPDPDIKRLAVRTEDHPVSYAEFEGTIPKGEYGGGTVMLWDRGSWAPIEGKSA
HEECCCCCCCCCHHEEEEECCCCCCCHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
KDLEKGHLHFILQGGRMQGEWLLIRLKKKPGEKRENWLLRKLQDEHAEEGDVLVERELTS
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHH
VLTGRSMAEIAADKKGEYPLAGKKDEAFLAQMEKASARNEAKAKQRKRRKAAPLPKFRQP
HHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
QLATLVDDVPAGNGWMHEIKFDGYRALVAAKGNDVRVFTRSGKDWTEKFGPLVGAIAALD
HHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHC
LPASLIDGEIVASDADGNPDFSKLQQVLKRGHGSQSKADRLAFHAFDLVELDGEDLAKLP
CCHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHEEEEEEEECCHHHHHCC
NIERKERLEAMLATAEPPIHVADHVIGAGEKLYEAMCAAGQEGIISKKIDAPYRHSRSKG
CCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCC
WVKVKCTRRQEFVIVGWKASRAKGRPFASLLMAQNEDGELVYKGNVGTGFTADELDMLAG
EEEEEEECCCEEEEEEEECCCCCCCCHHHHHEECCCCCCEEEECCCCCCCCHHHHHHHHH
KLKRLERKTPPVAVDAASARQVTWVAPKLVAEIAFAEFTADGKIRHGSYLGLRSDKDADD
HHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCEECCCEECCCCCCCCCC
VKPEKAAPAPKTAANVKISSRDRVVFPDSGQTKGELADYYEAVAGIMLPFAARRPVSLVR
CCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
CPQGRAKKCFFQKHDSGAFGDAVHHVPIMEKDGGTKGYLYVEDARGILQCVQMGTIEFHG
CCCCCCHHHHHEECCCCCCCCHHHCCCEEECCCCCCEEEEEECHHHHHHHHHHCCEEEEC
WASRTDDVELPDRMIFDLDPDEGLDFGDVKQAARDIKARLSDIGLVSFAMLSGGKGVHVV
CCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VPLAPGHSWDAHKDFARRFAEALSLAEPQRFTATMSKAKRKGKIFIDWLRNQRGSTAVLP
EECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEHHCCCCCEEEEC
YSARARRGAPVAVPIGWNELKDMQNAKSFSINDANRLLTRAGSKTLAGWGFADQELPDH
CCHHHCCCCCEEEECCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEECCCCCCCCCCCC
>Mature Secondary Structure 
ARRNDPLAIYNSKRDFAKTPEPSGKAESSAGGDLFIVQKHDATRLHWDLRLEVDGVLKS
CCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEEEEEEHHHHHH
WAVTKGPSPDPDIKRLAVRTEDHPVSYAEFEGTIPKGEYGGGTVMLWDRGSWAPIEGKSA
HEECCCCCCCCCHHEEEEECCCCCCCHHHCCCCCCCCCCCCCEEEEEECCCCCCCCCCCC
KDLEKGHLHFILQGGRMQGEWLLIRLKKKPGEKRENWLLRKLQDEHAEEGDVLVERELTS
CCCCCCCEEEEEECCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEHHHHHH
VLTGRSMAEIAADKKGEYPLAGKKDEAFLAQMEKASARNEAKAKQRKRRKAAPLPKFRQP
HHCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
QLATLVDDVPAGNGWMHEIKFDGYRALVAAKGNDVRVFTRSGKDWTEKFGPLVGAIAALD
HHHHHHHCCCCCCCEEEEEEECCEEEEEEECCCCEEEEEECCCHHHHHHHHHHHHHHHHC
LPASLIDGEIVASDADGNPDFSKLQQVLKRGHGSQSKADRLAFHAFDLVELDGEDLAKLP
CCHHHHCCEEEEECCCCCCCHHHHHHHHHHCCCCCCHHHHHHHEEEEEEEECCHHHHHCC
NIERKERLEAMLATAEPPIHVADHVIGAGEKLYEAMCAAGQEGIISKKIDAPYRHSRSKG
CCCHHHHHHHHHHCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCCHHCCCCCC
WVKVKCTRRQEFVIVGWKASRAKGRPFASLLMAQNEDGELVYKGNVGTGFTADELDMLAG
EEEEEEECCCEEEEEEEECCCCCCCCHHHHHEECCCCCCEEEECCCCCCCCHHHHHHHHH
KLKRLERKTPPVAVDAASARQVTWVAPKLVAEIAFAEFTADGKIRHGSYLGLRSDKDADD
HHHHHHHCCCCEEEECCCCCEEEEEHHHHHHHHHHHHCCCCCCEECCCEECCCCCCCCCC
VKPEKAAPAPKTAANVKISSRDRVVFPDSGQTKGELADYYEAVAGIMLPFAARRPVSLVR
CCCCCCCCCCCCCCEEEECCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
CPQGRAKKCFFQKHDSGAFGDAVHHVPIMEKDGGTKGYLYVEDARGILQCVQMGTIEFHG
CCCCCCHHHHHEECCCCCCCCHHHCCCEEECCCCCCEEEEEECHHHHHHHHHHCCEEEEC
WASRTDDVELPDRMIFDLDPDEGLDFGDVKQAARDIKARLSDIGLVSFAMLSGGKGVHVV
CCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
VPLAPGHSWDAHKDFARRFAEALSLAEPQRFTATMSKAKRKGKIFIDWLRNQRGSTAVLP
EECCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEHHCCCCCEEEEC
YSARARRGAPVAVPIGWNELKDMQNAKSFSINDANRLLTRAGSKTLAGWGFADQELPDH
CCHHHCCCCCEEEECCHHHHHHHHCCCCCCCCHHHHHHHHCCCCCEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]