Click here to switch to the map view.

The map label for this gene is sglT [H]

Identifier: 85373543

GI number: 85373543

Start: 739798

End: 741381

Strand: Direct

Name: sglT [H]

Synonym: ELI_03580

Alternate gene names: 85373543

Gene position: 739798-741381 (Clockwise)

Preceding gene: 85373539

Following gene: 85373545

Centisome position: 24.24

GC content: 62.88

Gene sequence:

>1584_bases
GTGTCGCTCGAGACCACCGATATTGTCATTATTGCGGGCTATGCGTTCGCGCTGCTCGGCATCGCCCTGTTCGTCAGTCG
CGAGCCCAAGGGACACGCCAAGAACACGGAGGATTACTTCCTCGCCGGTCGCGCGTTGCCGTGGTGGGCCATCGGCGCCT
CGCTGATCGCTTCCAATATCTCGGCCGAACAGATCATCGGCCAGTCGGGGCAGGGCTACGTCGTCGGTATCGCCATCGCG
GCCTACGAATGGCAGGCGGCGATCGTCCTGATCATCGTTGCCAAATACTTCCTGCCGATCTTCCTCAGGCGCAAGATCTA
CACCATGCCGCAATTCCTCGACCAGCGGTACGGACACGGCGTGAAAACGCTGATGAGCGTGTTTTGGGTCGCGCTCTACA
TCGCCGTCAACCTCACCACAGTGCTATGGCTGGGCGGGCTCGCTGTGACATCGCTCACGGGCTGGGGCGTCATGAGCGCG
ATGGCGGCGCTGGCGGGCTTTGCCGTACTCTACTCGCTCTACGGCGGCCTCAAGGCGGTTGCGCTGACCGACATCATCCA
GGTCGTCATCCTGATTATCGGCGGCATCGCCATCACCTGGATCGCGCTCGATGCGCTGCCTGCCGACGGCGCACTCGCGG
GCTTCGGCATGCTGATGCAGGAGATCCCGGGCCACTTCGCAATGATCCTCGACGAAAGCAATCCGTCCTACAGCGACCTG
CCGGGCATTTGGACGTTGCTCGGCGGGCTTTGGGTGCTGCATTTCAGTTACTGGGGGTTCAACCAGTATATCATCCAGCG
CGCGCTGGGCGCGGAGAGTTTGGGCGAAGCGCAGAAGGGCCTCGCCTTCGCGGCTTTGCTCAAGATCCTCGTGCCGTTCA
TCGTCGTCGTTCCCGGCATCGCCGCCATCATGCTGGCGCAGCAGGGGCTGCTGGACGGCCAGGCCCTCGCCGAACGGTCC
GACCGCACCTATGGCGAGCTGATGAGCTTCGCCCCGGCCGGCCTGCGCGGCCTCGTCTTCGCAGCGCTGATCGCGGCGGT
CGTCTCATCGCTCGCTTCGATGATGAATTCGATCTCGACCATCTTCACGATGGACCTCTATCGCGCGGCGAAGCCCGAGA
AGAGCGAACACCACTACGTGATCGTCGGCCGGGTCGCCGCCTTTGCGGCAATGCTGATCGCGCTCGTCCTGGCGCGGCCC
TTCATCGGCGGCTTCGAAAGCGGCTTCCAGACGGTGCAGGAATATACCGGCTTCATCGCGCCGGGAATCGTTGTCGTCTT
CCTGCTCGGCTTCTTCGACAGGAAGATGAACACGGCGGGCGCCTATACCGCGCTGCTTGGCTCGCTGGCGGTCAACGTCA
TGCTCAAGTTCGGCCTGCCGGACGTGCCCTTCATCATCCGTATCTGGGGCGTTTTCGTGCTTTCGATCATCGCGGCCGCC
CTCGTGTCGCGCATGACGGGGGCACCGGAAGAAGAGCGGACCGTGAAGCTGGGCGATATCGCCTTCGCCACCAGCATGCT
GTTCAATACGCTTGCCATGGTGGTCGTGGCGATACTCGTCGGGCTCTACATCTGGTTGTGGTAG

Upstream 100 bases:

>100_bases
GAATTCCACTGGACCTGTCCCGCGCGTTGGCTAGGTCCGGTCGTGAGGGAAGGATCGGGATGAGCCGGGGCAACCGGTCG
CCTGTGGGGGAGAACAGACC

Downstream 100 bases:

>100_bases
GCGCGGCGCGAGAGGACGCGCACGGCAGGTCTGAGCATGGGGTCCACAGGCCCGCCGGTAATCACCCGGCGACCTGCCTC
GACCCAGGCATGCGCATGCA

Product: sodium/glucose cotransport protein

Products: NA

Alternate protein names: Na(+)/glucose symporter [H]

Number of amino acids: Translated: 527; Mature: 526

Protein sequence:

>527_residues
MSLETTDIVIIAGYAFALLGIALFVSREPKGHAKNTEDYFLAGRALPWWAIGASLIASNISAEQIIGQSGQGYVVGIAIA
AYEWQAAIVLIIVAKYFLPIFLRRKIYTMPQFLDQRYGHGVKTLMSVFWVALYIAVNLTTVLWLGGLAVTSLTGWGVMSA
MAALAGFAVLYSLYGGLKAVALTDIIQVVILIIGGIAITWIALDALPADGALAGFGMLMQEIPGHFAMILDESNPSYSDL
PGIWTLLGGLWVLHFSYWGFNQYIIQRALGAESLGEAQKGLAFAALLKILVPFIVVVPGIAAIMLAQQGLLDGQALAERS
DRTYGELMSFAPAGLRGLVFAALIAAVVSSLASMMNSISTIFTMDLYRAAKPEKSEHHYVIVGRVAAFAAMLIALVLARP
FIGGFESGFQTVQEYTGFIAPGIVVVFLLGFFDRKMNTAGAYTALLGSLAVNVMLKFGLPDVPFIIRIWGVFVLSIIAAA
LVSRMTGAPEEERTVKLGDIAFATSMLFNTLAMVVVAILVGLYIWLW

Sequences:

>Translated_527_residues
MSLETTDIVIIAGYAFALLGIALFVSREPKGHAKNTEDYFLAGRALPWWAIGASLIASNISAEQIIGQSGQGYVVGIAIA
AYEWQAAIVLIIVAKYFLPIFLRRKIYTMPQFLDQRYGHGVKTLMSVFWVALYIAVNLTTVLWLGGLAVTSLTGWGVMSA
MAALAGFAVLYSLYGGLKAVALTDIIQVVILIIGGIAITWIALDALPADGALAGFGMLMQEIPGHFAMILDESNPSYSDL
PGIWTLLGGLWVLHFSYWGFNQYIIQRALGAESLGEAQKGLAFAALLKILVPFIVVVPGIAAIMLAQQGLLDGQALAERS
DRTYGELMSFAPAGLRGLVFAALIAAVVSSLASMMNSISTIFTMDLYRAAKPEKSEHHYVIVGRVAAFAAMLIALVLARP
FIGGFESGFQTVQEYTGFIAPGIVVVFLLGFFDRKMNTAGAYTALLGSLAVNVMLKFGLPDVPFIIRIWGVFVLSIIAAA
LVSRMTGAPEEERTVKLGDIAFATSMLFNTLAMVVVAILVGLYIWLW
>Mature_526_residues
SLETTDIVIIAGYAFALLGIALFVSREPKGHAKNTEDYFLAGRALPWWAIGASLIASNISAEQIIGQSGQGYVVGIAIAA
YEWQAAIVLIIVAKYFLPIFLRRKIYTMPQFLDQRYGHGVKTLMSVFWVALYIAVNLTTVLWLGGLAVTSLTGWGVMSAM
AALAGFAVLYSLYGGLKAVALTDIIQVVILIIGGIAITWIALDALPADGALAGFGMLMQEIPGHFAMILDESNPSYSDLP
GIWTLLGGLWVLHFSYWGFNQYIIQRALGAESLGEAQKGLAFAALLKILVPFIVVVPGIAAIMLAQQGLLDGQALAERSD
RTYGELMSFAPAGLRGLVFAALIAAVVSSLASMMNSISTIFTMDLYRAAKPEKSEHHYVIVGRVAAFAAMLIALVLARPF
IGGFESGFQTVQEYTGFIAPGIVVVFLLGFFDRKMNTAGAYTALLGSLAVNVMLKFGLPDVPFIIRIWGVFVLSIIAAAL
VSRMTGAPEEERTVKLGDIAFATSMLFNTLAMVVVAILVGLYIWLW

Specific function: Actively transports glucose into cells by Na(+) cotransport [H]

COG id: COG4146

COG function: function code R; Predicted symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family [H]

Homologues:

Organism=Homo sapiens, GI110835708, Length=547, Percent_Identity=29.981718464351, Blast_Score=212, Evalue=7e-55,
Organism=Homo sapiens, GI4507033, Length=474, Percent_Identity=30.5907172995781, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI17941285, Length=472, Percent_Identity=31.3559322033898, Blast_Score=205, Evalue=8e-53,
Organism=Homo sapiens, GI109659836, Length=490, Percent_Identity=33.0612244897959, Blast_Score=197, Evalue=2e-50,
Organism=Homo sapiens, GI4507031, Length=441, Percent_Identity=29.7052154195011, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI206597483, Length=455, Percent_Identity=32.5274725274725, Blast_Score=192, Evalue=6e-49,
Organism=Homo sapiens, GI109659839, Length=506, Percent_Identity=32.4110671936759, Blast_Score=191, Evalue=2e-48,
Organism=Homo sapiens, GI206597487, Length=480, Percent_Identity=31.0416666666667, Blast_Score=180, Evalue=4e-45,
Organism=Homo sapiens, GI14140236, Length=482, Percent_Identity=25.103734439834, Blast_Score=176, Evalue=3e-44,
Organism=Homo sapiens, GI157671931, Length=412, Percent_Identity=24.0291262135922, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI256985183, Length=432, Percent_Identity=26.1574074074074, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI4507035, Length=432, Percent_Identity=24.537037037037, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI167466278, Length=450, Percent_Identity=22.6666666666667, Blast_Score=82, Evalue=2e-15,
Organism=Escherichia coli, GI1790113, Length=467, Percent_Identity=30.1927194860814, Blast_Score=182, Evalue=3e-47,
Organism=Drosophila melanogaster, GI28573698, Length=463, Percent_Identity=25.9179265658747, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24651741, Length=430, Percent_Identity=23.4883720930233, Blast_Score=96, Evalue=9e-20,
Organism=Drosophila melanogaster, GI24651739, Length=444, Percent_Identity=25.2252252252252, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI161076631, Length=369, Percent_Identity=26.8292682926829, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24645928, Length=360, Percent_Identity=26.1111111111111, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI221459586, Length=433, Percent_Identity=26.5588914549654, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19920916, Length=398, Percent_Identity=24.6231155778894, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24650192, Length=348, Percent_Identity=26.1494252873563, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI28574994, Length=463, Percent_Identity=24.622030237581, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221459588, Length=384, Percent_Identity=26.5625, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221459584, Length=375, Percent_Identity=23.4666666666667, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI24641117, Length=451, Percent_Identity=23.2815964523282, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24640370, Length=392, Percent_Identity=26.0204081632653, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI281364280, Length=402, Percent_Identity=23.3830845771144, Blast_Score=72, Evalue=9e-13,
Organism=Drosophila melanogaster, GI281362918, Length=437, Percent_Identity=22.4256292906178, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001734
- InterPro:   IPR018212
- InterPro:   IPR019900 [H]

Pfam domain/function: PF00474 SSF [H]

EC number: NA

Molecular weight: Translated: 56676; Mature: 56545

Theoretical pI: Translated: 6.53; Mature: 6.53

Prosite motif: PS50283 NA_SOLUT_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLETTDIVIIAGYAFALLGIALFVSREPKGHAKNTEDYFLAGRALPWWAIGASLIASNI
CCCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCC
SAEQIIGQSGQGYVVGIAIAAYEWQAAIVLIIVAKYFLPIFLRRKIYTMPQFLDQRYGHG
CHHHHHCCCCCCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
VKTLMSVFWVALYIAVNLTTVLWLGGLAVTSLTGWGVMSAMAALAGFAVLYSLYGGLKAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTDIIQVVILIIGGIAITWIALDALPADGALAGFGMLMQEIPGHFAMILDESNPSYSDL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
PGIWTLLGGLWVLHFSYWGFNQYIIQRALGAESLGEAQKGLAFAALLKILVPFIVVVPGI
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAIMLAQQGLLDGQALAERSDRTYGELMSFAPAGLRGLVFAALIAAVVSSLASMMNSIST
HHHHHHHHCCCCHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IFTMDLYRAAKPEKSEHHYVIVGRVAAFAAMLIALVLARPFIGGFESGFQTVQEYTGFIA
HHHHHHHHHCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
PGIVVVFLLGFFDRKMNTAGAYTALLGSLAVNVMLKFGLPDVPFIIRIWGVFVLSIIAAA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
LVSRMTGAPEEERTVKLGDIAFATSMLFNTLAMVVVAILVGLYIWLW
HHHHHCCCCCHHCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLETTDIVIIAGYAFALLGIALFVSREPKGHAKNTEDYFLAGRALPWWAIGASLIASNI
CCCCCCEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEECCCCCHHHHHHHHHHHCC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HHHHHCCCCCHHCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8652595; 10835424; 10757971 [H]