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The map label for this gene is dhlA [H]

Identifier: 85373522

GI number: 85373522

Start: 717147

End: 718055

Strand: Direct

Name: dhlA [H]

Synonym: ELI_03475

Alternate gene names: 85373522

Gene position: 717147-718055 (Clockwise)

Preceding gene: 85373521

Following gene: 85373525

Centisome position: 23.49

GC content: 64.58

Gene sequence:

>909_bases
ATGACCGAAGCCCTGCGTACCCCAGACGAAGCCTTCGCCGAAGTCCCCGACTACCCCTTCGCGCCGCATTACGTCGACGA
CCTGCCCGGCTATGAGGGCCTGCGCGTCCACTATATCGACGAGCCAGGTGCCGAAGATGGGCCGGAGGCTGGCAAAACCT
TTCTATGCCTCCATGGCCAGCCGAGCTGGTCCTTCCTCTACCGCAAGATGATCCCGGTCTTCACCGCCGCCGGGGGGAGG
GCGGTCGCGCCCGACCTGCTCGGCTTCGGGAAGTCCGACAAACCTGTCGACGACGAAACCTATACCTACAATTTCCATCG
CGGCATGCTGATAGCCTTCATCGAGAAGCTGGACCTCACCAGCATCACACTCGTCTGCCAGGACTGGGGCGGCATCCTCG
GCCTCGGGATCGTGCCCGACATGGCCGATCGCTTCGAACGGCTGATCGTGATGAACACCGCTATTCCCATCGGCGAATCG
CCGGGGCCGGGTTTCGAGGCGTGGAAGGCCTTCAATCGCAGTCAGCCCAACATGGATGTCGCGGGGCTGTTCAAGCGCGG
CACACCCGACCTGACCGACGCAGAAGCGGCGGCCTACGGCGCTCCGTTCCCCGACCAGCGCTACAAGGCGGGGGTGCGTC
GCTTCCCCGAGCTGGTGCCGGTTAGCCCCGAGATGCAGGGCGTCGAGGAAGGCAAGCGTGCACGCGAATTCTGGGCCAAC
GAATGGAGCGGCAAGAGCTTCATGGCCATCGGCATGCAGGACCCGGTGCTGGGTCCGCCCGCGATGCGCGGGCTGCAGAA
GCAGATCCGTGGCTGCCCCGATCCGATGGAAGTGCCCGATGGCGGGCATTTCGTGCAGGAAAAAGGCGAAGGGATTGCGC
GCGCTGCGCTGGAAAGCTTCGCCGCTTAG

Upstream 100 bases:

>100_bases
TCGATCCGGCGGGCGCGGAGATTATCCGCTCGGATCGCAAGCGATAGGTGCTTGTCGGCTCTCGCGCTGGCTGCGATGAC
TGGCGCGAGAGGAGACCCGC

Downstream 100 bases:

>100_bases
GCGACCGGGCGGAGCCTGGCTTTTAGCCTGATCGTCACGGTCTTGCCCACGATCAGCGAATAGGCCGTCATCCCGAAGTC
GCGGCGATCGATCCGGGTCT

Product: haloalkane dehalogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MTEALRTPDEAFAEVPDYPFAPHYVDDLPGYEGLRVHYIDEPGAEDGPEAGKTFLCLHGQPSWSFLYRKMIPVFTAAGGR
AVAPDLLGFGKSDKPVDDETYTYNFHRGMLIAFIEKLDLTSITLVCQDWGGILGLGIVPDMADRFERLIVMNTAIPIGES
PGPGFEAWKAFNRSQPNMDVAGLFKRGTPDLTDAEAAAYGAPFPDQRYKAGVRRFPELVPVSPEMQGVEEGKRAREFWAN
EWSGKSFMAIGMQDPVLGPPAMRGLQKQIRGCPDPMEVPDGGHFVQEKGEGIARAALESFAA

Sequences:

>Translated_302_residues
MTEALRTPDEAFAEVPDYPFAPHYVDDLPGYEGLRVHYIDEPGAEDGPEAGKTFLCLHGQPSWSFLYRKMIPVFTAAGGR
AVAPDLLGFGKSDKPVDDETYTYNFHRGMLIAFIEKLDLTSITLVCQDWGGILGLGIVPDMADRFERLIVMNTAIPIGES
PGPGFEAWKAFNRSQPNMDVAGLFKRGTPDLTDAEAAAYGAPFPDQRYKAGVRRFPELVPVSPEMQGVEEGKRAREFWAN
EWSGKSFMAIGMQDPVLGPPAMRGLQKQIRGCPDPMEVPDGGHFVQEKGEGIARAALESFAA
>Mature_301_residues
TEALRTPDEAFAEVPDYPFAPHYVDDLPGYEGLRVHYIDEPGAEDGPEAGKTFLCLHGQPSWSFLYRKMIPVFTAAGGRA
VAPDLLGFGKSDKPVDDETYTYNFHRGMLIAFIEKLDLTSITLVCQDWGGILGLGIVPDMADRFERLIVMNTAIPIGESP
GPGFEAWKAFNRSQPNMDVAGLFKRGTPDLTDAEAAAYGAPFPDQRYKAGVRRFPELVPVSPEMQGVEEGKRAREFWANE
WSGKSFMAIGMQDPVLGPPAMRGLQKQIRGCPDPMEVPDGGHFVQEKGEGIARAALESFAA

Specific function: Catalyzes hydrolytic cleavage of carbon-halogen bonds in halogenated aliphatic compounds, leading to the formation of the corresponding primary alcohols, halide ions and protons. Has a broad substrate specificity, which includes terminally mono- and di- c

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the haloalkane dehalogenase family. Type 1 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.5 [H]

Molecular weight: Translated: 33130; Mature: 32999

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEALRTPDEAFAEVPDYPFAPHYVDDLPGYEGLRVHYIDEPGAEDGPEAGKTFLCLHGQ
CCCCCCCCHHHHHHCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECC
PSWSFLYRKMIPVFTAAGGRAVAPDLLGFGKSDKPVDDETYTYNFHRGMLIAFIEKLDLT
CCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCC
SITLVCQDWGGILGLGIVPDMADRFERLIVMNTAIPIGESPGPGFEAWKAFNRSQPNMDV
EEEEEEECCCCEEECCCCHHHHHHHHHEEHEECCCCCCCCCCCCHHHHHHHCCCCCCCCH
AGLFKRGTPDLTDAEAAAYGAPFPDQRYKAGVRRFPELVPVSPEMQGVEEGKRAREFWAN
HHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHC
EWSGKSFMAIGMQDPVLGPPAMRGLQKQIRGCPDPMEVPDGGHFVQEKGEGIARAALESF
CCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHH
AA
CC
>Mature Secondary Structure 
TEALRTPDEAFAEVPDYPFAPHYVDDLPGYEGLRVHYIDEPGAEDGPEAGKTFLCLHGQ
CCCCCCCHHHHHHCCCCCCCCCHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEEEECC
PSWSFLYRKMIPVFTAAGGRAVAPDLLGFGKSDKPVDDETYTYNFHRGMLIAFIEKLDLT
CCHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCCCCCCCEEEECCCCHHHHHHHHHCCC
SITLVCQDWGGILGLGIVPDMADRFERLIVMNTAIPIGESPGPGFEAWKAFNRSQPNMDV
EEEEEEECCCCEEECCCCHHHHHHHHHEEHEECCCCCCCCCCCCHHHHHHHCCCCCCCCH
AGLFKRGTPDLTDAEAAAYGAPFPDQRYKAGVRRFPELVPVSPEMQGVEEGKRAREFWAN
HHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHC
EWSGKSFMAIGMQDPVLGPPAMRGLQKQIRGCPDPMEVPDGGHFVQEKGEGIARAALESF
CCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHH
AA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2687254; 4019411; 3398051; 2026135; 8355275; 8515812; 9790663; 10508409; 10393294 [H]