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The map label for this gene is fnrL [H]

Identifier: 85373387

GI number: 85373387

Start: 593176

End: 593871

Strand: Reverse

Name: fnrL [H]

Synonym: ELI_02800

Alternate gene names: 85373387

Gene position: 593871-593176 (Counterclockwise)

Preceding gene: 85373388

Following gene: 85373371

Centisome position: 19.46

GC content: 67.96

Gene sequence:

>696_bases
ATGAACCTCGCCTGCGCCTCCTGCCCGGTGAGGGAGCGCGCCGCCTGTGCCGTTCTCACCGAAGCGGAGCGCGGCGAACT
GGCCCGCGCCGGGCGCACTGTTAAACTCAAGCGGGGCGAGATGCTGTTCGCAGCGGGCGACGAGGATCATGCCTGCGCCA
CGCTGCTGAGAGGCGCGCTGAAGGTCAGCGCGGTCGATCGCGAAGGCGAGGAGCGGATCCTTGCGCTGATCCATCCCGCA
GGGTTCGTGGGTGAGTTGTTCCAGCCCTTCGCCCACCATGATGTCGTGGCGCTCACCGATTGCGAGCTGTGCGTTTTCGC
GCGCCGCGAAATGGAAGCGGCGCTGGAACGGCACCCCGCCCTCGCCCGCGCCATGCTGCGCCGGTCGCAGGACGACCTGC
ATGCGGCGCGCGAACTGCTCGAGCTGACGGGGAAGCAGGATGCGGCAACGCGGCTGGCAGGCCTGATCATGGCGATGGCG
CGCGCGGCGAGCGATTCGCCGTGCCATCCGAGCCAGGCCTTCGACCTGCCGCTGACCCGCGGCGAAATGGCGCAGATGCT
GGGCCTCACCATCGAGACCGTCAGCCGCAGAATGTCCAAATTCGAGAAGGACGGCCTGATCGCCAAGAAAGGTGCGCGCG
GGATCGAACTCGTCGACCCCGCGCGTCTTGAAGCGCTGGTGGGAGTGGGCCTCTAA

Upstream 100 bases:

>100_bases
TCGAGCAGCGCGCCGAAATCGTCGAAGCGCAGGCGCAGGTCCAGGCGCTGCTCGAAGAGGAGGACGCGGTGCTCCGACGG
TTGAAGGGCGCGCTTGCGCG

Downstream 100 bases:

>100_bases
ACCAGCGCCGCAATCGTTACGCAGGCGATGCCCCAGGCGAGGATCAGTACCGGCAGGATCAACATCTGGATTGCCGCCTC
GCTGGCAGGCAGGCGGCCGG

Product: transcriptional activator protein FnrL

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MNLACASCPVRERAACAVLTEAERGELARAGRTVKLKRGEMLFAAGDEDHACATLLRGALKVSAVDREGEERILALIHPA
GFVGELFQPFAHHDVVALTDCELCVFARREMEAALERHPALARAMLRRSQDDLHAARELLELTGKQDAATRLAGLIMAMA
RAASDSPCHPSQAFDLPLTRGEMAQMLGLTIETVSRRMSKFEKDGLIAKKGARGIELVDPARLEALVGVGL

Sequences:

>Translated_231_residues
MNLACASCPVRERAACAVLTEAERGELARAGRTVKLKRGEMLFAAGDEDHACATLLRGALKVSAVDREGEERILALIHPA
GFVGELFQPFAHHDVVALTDCELCVFARREMEAALERHPALARAMLRRSQDDLHAARELLELTGKQDAATRLAGLIMAMA
RAASDSPCHPSQAFDLPLTRGEMAQMLGLTIETVSRRMSKFEKDGLIAKKGARGIELVDPARLEALVGVGL
>Mature_231_residues
MNLACASCPVRERAACAVLTEAERGELARAGRTVKLKRGEMLFAAGDEDHACATLLRGALKVSAVDREGEERILALIHPA
GFVGELFQPFAHHDVVALTDCELCVFARREMEAALERHPALARAMLRRSQDDLHAARELLELTGKQDAATRLAGLIMAMA
RAASDSPCHPSQAFDLPLTRGEMAQMLGLTIETVSRRMSKFEKDGLIAKKGARGIELVDPARLEALVGVGL

Specific function: Anaerobic regulatory protein; transcriptional activator of hemA. Appears to regulate other genes [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787595, Length=213, Percent_Identity=28.6384976525822, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 24977; Mature: 24977

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50042 CNMP_BINDING_3 ; PS00042 HTH_CRP_1 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
3.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLACASCPVRERAACAVLTEAERGELARAGRTVKLKRGEMLFAAGDEDHACATLLRGAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCHHHHHHHHHHH
KVSAVDREGEERILALIHPAGFVGELFQPFAHHDVVALTDCELCVFARREMEAALERHPA
HHHHCCCCCCHHEEEEECCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCHH
LARAMLRRSQDDLHAARELLELTGKQDAATRLAGLIMAMARAASDSPCHPSQAFDLPLTR
HHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
GEMAQMLGLTIETVSRRMSKFEKDGLIAKKGARGIELVDPARLEALVGVGL
HHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MNLACASCPVRERAACAVLTEAERGELARAGRTVKLKRGEMLFAAGDEDHACATLLRGAL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCEEEEECCCCHHHHHHHHHHH
KVSAVDREGEERILALIHPAGFVGELFQPFAHHDVVALTDCELCVFARREMEAALERHPA
HHHHCCCCCCHHEEEEECCCHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCHH
LARAMLRRSQDDLHAARELLELTGKQDAATRLAGLIMAMARAASDSPCHPSQAFDLPLTR
HHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCH
GEMAQMLGLTIETVSRRMSKFEKDGLIAKKGARGIELVDPARLEALVGVGL
HHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592416 [H]