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The map label for this gene is gst [C]

Identifier: 85373357

GI number: 85373357

Start: 568905

End: 569531

Strand: Reverse

Name: gst [C]

Synonym: ELI_02650

Alternate gene names: 85373357

Gene position: 569531-568905 (Counterclockwise)

Preceding gene: 85373358

Following gene: 85373356

Centisome position: 18.66

GC content: 63.32

Gene sequence:

>627_bases
ATGGCCGATTTCACTTTCTATACCGTCGCCATGAGCCGCGGGCAGATCGCGCGCTGGGCGCTGCACGAGGCGGGCGCCGA
CTACAATACCGAGATGATGACGTGGGAGACCCGGCCCAAGAGCTTCCGTGCCATCAATCCGATGAACAAGGTCCCCGCGC
TGGTGCATCATCACAACGGGCATGACCATGTCATCACCGAATGCGCGGCGATCTGCCACTATCTGGCGGAGACCCACCCG
GGACCGGAATTGGCCCCAACCTTCGAGGAAAAGGCCGACTATTTGCGCTGGCTGTTCTTCGCCGCCGGGCCGTTGGAACA
GGCGGTCGTGGCCAAATCGATGGGCTGGGAAGTGCCCGAAGACCGCAGCGGGATGGCCGGGTTCGGTTCTTTCGATCTCA
CCATAGACGCTCTCGATAGCTGGCTCACGGACCGGCAGTTCGTCTGCGGCGACAGGTTCACCATGGCGGATGTCTATGTC
GGCAGCCAGGTCGACTGGGGCCTGCAATTCGGCACCCTGCCCGAGCGCGACTCCCTGACCGCCTATCGCGAGCGGATCAA
TGCGCGCCCTGCCAAGCAGGAGGCAAATGCGATCGACATGGCCGCGATGGAGCCGGCCGATGGCTGA

Upstream 100 bases:

>100_bases
CAACGGGCCGATGGAAATCCCCGGCGGCGACCACGTCTTCCAGGGGGTCGACCCGCAAGGCGCGCTATTCTCCATCATCG
GTAGCAAGGGAGCCTGATCG

Downstream 100 bases:

>100_bases
CAGCAAGCTCGCGCTGTGCCTGTGGCTCGACCAGGGCGCGGAAGAGGCCGCCAATTTCTATTGCGACCTCTTTCCCGACA
GCGACATTACCCGGGTCGAC

Product: hypothetical protein

Products: HX; R-S-Glutathione; S-(2,4-dinitrophenyl)glutathione [C]

Alternate protein names: Glutathione S-Transferase Domain-Containing Protein; Glutathione S-Transferase Domain Protein; Glutathione S-Transferase-Like Protein; Glutathione S-Transferase Protein; Glutathione S-Transferase Domain; Glutathione S-Transferase-Like; Glutathione S-Transferase N-Terminal Domain Protein; Glutathione Transferase; Glutathione S-Transferase Family Protein; Glutathione S-Transferase N-Terminal Domain-Containing; Glutathione S-Transferase III; Transcriptional Regulator; Glutathionine S-Transferase; GSH-Dependent Dehydroascorbate Reductase; Gluthione S-Transferase

Number of amino acids: Translated: 208; Mature: 207

Protein sequence:

>208_residues
MADFTFYTVAMSRGQIARWALHEAGADYNTEMMTWETRPKSFRAINPMNKVPALVHHHNGHDHVITECAAICHYLAETHP
GPELAPTFEEKADYLRWLFFAAGPLEQAVVAKSMGWEVPEDRSGMAGFGSFDLTIDALDSWLTDRQFVCGDRFTMADVYV
GSQVDWGLQFGTLPERDSLTAYRERINARPAKQEANAIDMAAMEPADG

Sequences:

>Translated_208_residues
MADFTFYTVAMSRGQIARWALHEAGADYNTEMMTWETRPKSFRAINPMNKVPALVHHHNGHDHVITECAAICHYLAETHP
GPELAPTFEEKADYLRWLFFAAGPLEQAVVAKSMGWEVPEDRSGMAGFGSFDLTIDALDSWLTDRQFVCGDRFTMADVYV
GSQVDWGLQFGTLPERDSLTAYRERINARPAKQEANAIDMAAMEPADG
>Mature_207_residues
ADFTFYTVAMSRGQIARWALHEAGADYNTEMMTWETRPKSFRAINPMNKVPALVHHHNGHDHVITECAAICHYLAETHPG
PELAPTFEEKADYLRWLFFAAGPLEQAVVAKSMGWEVPEDRSGMAGFGSFDLTIDALDSWLTDRQFVCGDRFTMADVYVG
SQVDWGLQFGTLPERDSLTAYRERINARPAKQEANAIDMAAMEPADG

Specific function: Conjugation Of Reduced Glutathione To A Wide Number Of Exogenous And Endogenous Hydrophobic Electrophiles. [C]

COG id: COG0625

COG function: function code O; Glutathione S-transferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.5.1.18 [C]

Molecular weight: Translated: 23305; Mature: 23174

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADFTFYTVAMSRGQIARWALHEAGADYNTEMMTWETRPKSFRAINPMNKVPALVHHHNG
CCCEEEEEEEECCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHCCHHEECCCC
HDHVITECAAICHYLAETHPGPELAPTFEEKADYLRWLFFAAGPLEQAVVAKSMGWEVPE
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
DRSGMAGFGSFDLTIDALDSWLTDRQFVCGDRFTMADVYVGSQVDWGLQFGTLPERDSLT
CCCCCCCCCCCEEEHHHHHHHHCCCCEECCCCEEEEEEEECCCCCCCEEECCCCCCCHHH
AYRERINARPAKQEANAIDMAAMEPADG
HHHHHHCCCCCHHHCCCHHHHCCCCCCC
>Mature Secondary Structure 
ADFTFYTVAMSRGQIARWALHEAGADYNTEMMTWETRPKSFRAINPMNKVPALVHHHNG
CCEEEEEEEECCCCHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCHHHCCHHEECCCC
HDHVITECAAICHYLAETHPGPELAPTFEEKADYLRWLFFAAGPLEQAVVAKSMGWEVPE
CHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCC
DRSGMAGFGSFDLTIDALDSWLTDRQFVCGDRFTMADVYVGSQVDWGLQFGTLPERDSLT
CCCCCCCCCCCEEEHHHHHHHHCCCCEECCCCEEEEEEEECCCCCCCEEECCCCCCCHHH
AYRERINARPAKQEANAIDMAAMEPADG
HHHHHHCCCCCHHHCCCHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: RX; Glutathione; 1-chloro-2,4-dinitrobenzene; reduced glutathione [C]

Specific reaction: RX + Glutathione = HX + R-S-Glutathione 1-chloro-2,4-dinitrobenzene + reduced glutathione = S-(2,4-dinitrophenyl)glutathione [C]

General reaction: Aryl group transfer [C]

Inhibitor: Cd2+; CibacronBlue; Co2+; Cu2+; Hematin; Hg2+; Ni2+; Sulfophthaleins; Tributyl tinacetate; Triethyl tinbromide; Zn2+ [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA