BacMap

Definition	Erythrobacter litoralis HTCC2594 chromosome, complete genome.
Accession	NC_007722
Length	3,052,398

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The map label for this gene is yqjQ [H]

Identifier: 85373350

GI number: 85373350

Start: 564887

End: 565702

Strand: Reverse

Name: yqjQ [H]

Synonym: ELI_02615

Alternate gene names: 85373350

Gene position: 565702-564887 (Counterclockwise)

Preceding gene: 85373351

Following gene: 85373349

Centisome position: 18.53

GC content: 65.56

Gene sequence:

>816_bases
ATGAGTTACGACGGACAATGCTGGTGGATTACCGGCGCATCGAGCGGCATCGGCGCGGCGCTGGCGAAGGAACTGGGTGA
GCGCGGGGCGCGGGTCATCCTGTCTGGCCGCGATGAGGCGCGTCTGGCCGAGGTGGCTGGTGAGATCGCGACCGAGACGA
TGACCCTGCCCTTCGACGTGCGCGACGAGGACGCGATGCTGGCGGCGACAGAGAAGGCGATCGAATGGTCGGGAGGCGTG
GACGGCTTCGTCGCCAATGCCGGCGTGTCGCAGCGCAGCCGGGCGACGAAGACCGACATGCAGGTCTATCGCGACATCAT
CGATATCGACCTCACCGCGCAGATCGCCGCGACGCAGGCGTTGCTGCCGCACTTGGCCGCGCGCAAGTCGGGCAGCCTGC
TGTTCATCTCCTCGATCGCAGGAAAGGTCGGTGTGCCGATGCGCACCGCCTATTGCGCGGCCAAGTTCGGCCTCGCAGGC
TATGCCGATGCGCTGCGCGCCGAGCTTTCGCAGGACGGGATAGGCGTCCACGTGATCTACCCCGGCTCGATCGCGACCAA
TGTCAGCCGCAATGCGCTGTCCGCCGACGGCAGCGCACGCGGGCGCAGCGACGATGTGATCGACAACGGGATCGCGCCCG
ACGAAGCCGCCAAAACGATGCTCGACGCCGTGGCGCTCAACCAGCGCGAGATCATTGTTGCGGAAGGCATGGAAGAGGCC
ATGGGCGAAATGCGCCGCACGCCCGACCAGCTGTTCGACCAAGTCGCTGCGATGGTAGCAAACGGCTATATGGAGAAAAT
GGAAGCGGACGGCTAA

Upstream 100 bases:

>100_bases
TCGCTTCCCGACCGTGCCGGGCGATGACGAGGAATTCATTCCGCTGCCCGAGGGAAAGCCCAAGACGGTCAGCTATCCAT
AGTTCAACAAGGGAGAGGAC

Downstream 100 bases:

>100_bases
ACGCCATGGAACAAGTGCGCGTCACCCTGGAAAACAGGATTGAGCTGGATGTGGTGGATACCGGGCCGCGTGATGGCCCT
GCTCTGATCTTCCTGCACGG

Product: putative oxidoreductase/dehydrogenase

Products: (3R)-hydroxyacyl-[acyl-carrier-protein]; NADP; NADPH; Proton; beta-ketoacyl-ACP [C]

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSYDGQCWWITGASSGIGAALAKELGERGARVILSGRDEARLAEVAGEIATETMTLPFDVRDEDAMLAATEKAIEWSGGV
DGFVANAGVSQRSRATKTDMQVYRDIIDIDLTAQIAATQALLPHLAARKSGSLLFISSIAGKVGVPMRTAYCAAKFGLAG
YADALRAELSQDGIGVHVIYPGSIATNVSRNALSADGSARGRSDDVIDNGIAPDEAAKTMLDAVALNQREIIVAEGMEEA
MGEMRRTPDQLFDQVAAMVANGYMEKMEADG

Sequences:

>Translated_271_residues
MSYDGQCWWITGASSGIGAALAKELGERGARVILSGRDEARLAEVAGEIATETMTLPFDVRDEDAMLAATEKAIEWSGGV
DGFVANAGVSQRSRATKTDMQVYRDIIDIDLTAQIAATQALLPHLAARKSGSLLFISSIAGKVGVPMRTAYCAAKFGLAG
YADALRAELSQDGIGVHVIYPGSIATNVSRNALSADGSARGRSDDVIDNGIAPDEAAKTMLDAVALNQREIIVAEGMEEA
MGEMRRTPDQLFDQVAAMVANGYMEKMEADG
>Mature_270_residues
SYDGQCWWITGASSGIGAALAKELGERGARVILSGRDEARLAEVAGEIATETMTLPFDVRDEDAMLAATEKAIEWSGGVD
GFVANAGVSQRSRATKTDMQVYRDIIDIDLTAQIAATQALLPHLAARKSGSLLFISSIAGKVGVPMRTAYCAAKFGLAGY
ADALRAELSQDGIGVHVIYPGSIATNVSRNALSADGSARGRSDDVIDNGIAPDEAAKTMLDAVALNQREIIVAEGMEEAM
GEMRRTPDQLFDQVAAMVANGYMEKMEADG

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=257, Percent_Identity=36.5758754863813, Blast_Score=152, Evalue=4e-37,
Organism=Homo sapiens, GI7706318, Length=235, Percent_Identity=32.3404255319149, Blast_Score=138, Evalue=5e-33,
Organism=Homo sapiens, GI157739938, Length=267, Percent_Identity=26.9662921348315, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI150247226, Length=187, Percent_Identity=33.6898395721925, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI223718074, Length=204, Percent_Identity=31.8627450980392, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI4503817, Length=180, Percent_Identity=28.8888888888889, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI19743808, Length=183, Percent_Identity=29.5081967213115, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI7705855, Length=195, Percent_Identity=29.7435897435897, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI44680136, Length=190, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI44680133, Length=190, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI17738292, Length=190, Percent_Identity=28.4210526315789, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI142976729, Length=256, Percent_Identity=23.046875, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI5031737, Length=188, Percent_Identity=30.3191489361702, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI32483357, Length=187, Percent_Identity=32.0855614973262, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI33667109, Length=188, Percent_Identity=30.3191489361702, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI32455239, Length=235, Percent_Identity=27.2340425531915, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI5031765, Length=235, Percent_Identity=27.2340425531915, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI22507405, Length=186, Percent_Identity=31.1827956989247, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI210032110, Length=255, Percent_Identity=22.3529411764706, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI40254986, Length=216, Percent_Identity=26.8518518518519, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI7657478, Length=185, Percent_Identity=29.7297297297297, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI38348362, Length=175, Percent_Identity=30.2857142857143, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI31542939, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI38424085, Length=175, Percent_Identity=30.2857142857143, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI40548397, Length=188, Percent_Identity=26.5957446808511, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI214010158, Length=188, Percent_Identity=26.5957446808511, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI214010156, Length=188, Percent_Identity=26.5957446808511, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI22758144, Length=188, Percent_Identity=26.5957446808511, Blast_Score=71, Evalue=1e-12,
Organism=Homo sapiens, GI226371731, Length=186, Percent_Identity=30.1075268817204, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI40807363, Length=191, Percent_Identity=28.2722513089005, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI40254992, Length=186, Percent_Identity=24.1935483870968, Blast_Score=66, Evalue=3e-11,
Organism=Homo sapiens, GI50726952, Length=191, Percent_Identity=29.3193717277487, Blast_Score=65, Evalue=8e-11,
Organism=Homo sapiens, GI126723191, Length=178, Percent_Identity=26.4044943820225, Blast_Score=65, Evalue=9e-11,
Organism=Escherichia coli, GI1787335, Length=196, Percent_Identity=31.6326530612245, Blast_Score=98, Evalue=6e-22,
Organism=Escherichia coli, GI1790717, Length=194, Percent_Identity=30.9278350515464, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI87082100, Length=188, Percent_Identity=35.6382978723404, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1787526, Length=195, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=8e-16,
Organism=Escherichia coli, GI87082160, Length=191, Percent_Identity=28.2722513089005, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI1786701, Length=232, Percent_Identity=30.1724137931034, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787820, Length=226, Percent_Identity=27.4336283185841, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789208, Length=213, Percent_Identity=25.3521126760563, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789057, Length=230, Percent_Identity=26.0869565217391, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI17570069, Length=226, Percent_Identity=36.283185840708, Blast_Score=124, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71997402, Length=223, Percent_Identity=35.4260089686099, Blast_Score=120, Evalue=6e-28,
Organism=Caenorhabditis elegans, GI71994604, Length=189, Percent_Identity=28.5714285714286, Blast_Score=94, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI71994600, Length=188, Percent_Identity=27.6595744680851, Blast_Score=85, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17538486, Length=207, Percent_Identity=33.3333333333333, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17538480, Length=195, Percent_Identity=29.7435897435897, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=195, Percent_Identity=29.7435897435897, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI32563809, Length=279, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17507613, Length=279, Percent_Identity=25.8064516129032, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=186, Percent_Identity=27.9569892473118, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI193210355, Length=203, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=195, Percent_Identity=30.2564102564103, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=258, Percent_Identity=27.5193798449612, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203117, Length=191, Percent_Identity=27.7486910994764, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI193203115, Length=187, Percent_Identity=28.3422459893048, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17531453, Length=197, Percent_Identity=28.4263959390863, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17560332, Length=201, Percent_Identity=28.8557213930348, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=191, Percent_Identity=28.2722513089005, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17559104, Length=191, Percent_Identity=33.5078534031414, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=195, Percent_Identity=28.7179487179487, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17561402, Length=193, Percent_Identity=25.3886010362694, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17563726, Length=198, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=186, Percent_Identity=27.9569892473118, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=193, Percent_Identity=30.0518134715026, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=195, Percent_Identity=27.6923076923077, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=205, Percent_Identity=27.8048780487805, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17555706, Length=180, Percent_Identity=28.3333333333333, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17560676, Length=202, Percent_Identity=28.2178217821782, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25152911, Length=217, Percent_Identity=29.0322580645161, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=193, Percent_Identity=30.0518134715026, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=213, Percent_Identity=27.6995305164319, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17508895, Length=185, Percent_Identity=25.9459459459459, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=193, Percent_Identity=32.6424870466321, Blast_Score=88, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6319635, Length=235, Percent_Identity=25.9574468085106, Blast_Score=69, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322861, Length=192, Percent_Identity=28.6458333333333, Blast_Score=68, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6324126, Length=189, Percent_Identity=28.042328042328, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21358495, Length=260, Percent_Identity=31.9230769230769, Blast_Score=145, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24580925, Length=212, Percent_Identity=33.0188679245283, Blast_Score=98, Evalue=7e-21,
Organism=Drosophila melanogaster, GI281364892, Length=254, Percent_Identity=25.9842519685039, Blast_Score=88, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24644339, Length=192, Percent_Identity=30.7291666666667, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI23397609, Length=193, Percent_Identity=31.0880829015544, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24640442, Length=200, Percent_Identity=29, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355319, Length=190, Percent_Identity=28.4210526315789, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28571526, Length=193, Percent_Identity=25.3886010362694, Blast_Score=74, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24640492, Length=244, Percent_Identity=25.8196721311475, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21357673, Length=209, Percent_Identity=26.3157894736842, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI18859837, Length=190, Percent_Identity=28.4210526315789, Blast_Score=72, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281364494, Length=196, Percent_Identity=30.6122448979592, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21355631, Length=256, Percent_Identity=25.78125, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI21357041, Length=193, Percent_Identity=24.8704663212435, Blast_Score=69, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24649181, Length=193, Percent_Identity=25.3886010362694, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI161076933, Length=187, Percent_Identity=25.668449197861, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24643142, Length=184, Percent_Identity=29.8913043478261, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24584748, Length=187, Percent_Identity=25.668449197861, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.1.1.100 [C]

Molecular weight: Translated: 28595; Mature: 28463

Theoretical pI: Translated: 4.36; Mature: 4.36

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYDGQCWWITGASSGIGAALAKELGERGARVILSGRDEARLAEVAGEIATETMTLPFDV
CCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHEEECCCCC
RDEDAMLAATEKAIEWSGGVDGFVANAGVSQRSRATKTDMQVYRDIIDIDLTAQIAATQA
CCCCHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LLPHLAARKSGSLLFISSIAGKVGVPMRTAYCAAKFGLAGYADALRAELSQDGIGVHVIY
HHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEE
PGSIATNVSRNALSADGSARGRSDDVIDNGIAPDEAAKTMLDAVALNQREIIVAEGMEEA
CCHHHCCCCHHHHCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHH
MGEMRRTPDQLFDQVAAMVANGYMEKMEADG
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SYDGQCWWITGASSGIGAALAKELGERGARVILSGRDEARLAEVAGEIATETMTLPFDV
CCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHEEECCCCC
RDEDAMLAATEKAIEWSGGVDGFVANAGVSQRSRATKTDMQVYRDIIDIDLTAQIAATQA
CCCCHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LLPHLAARKSGSLLFISSIAGKVGVPMRTAYCAAKFGLAGYADALRAELSQDGIGVHVIY
HHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHCCCCCEEEEEE
PGSIATNVSRNALSADGSARGRSDDVIDNGIAPDEAAKTMLDAVALNQREIIVAEGMEEA
CCHHHCCCCHHHHCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHCCCCEEEEECCHHHH
MGEMRRTPDQLFDQVAAMVANGYMEKMEADG
HHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NADPH [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Oxoacyl-[acyl-carrier-protein]; NADPH; D-3-hydroxy-acyl-ACP; NADP [C]

Specific reaction: Oxoacyl-[acyl-carrier-protein] + NADPH = (3R)-hydroxyacyl-[acyl-carrier-protein] + NADP+ D-3-hydroxy-acyl-ACP + NADP = NADPH + Proton + beta-ketoacyl-ACP [C]

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]