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The map label for this gene is infA

Identifier: 85373324

GI number: 85373324

Start: 535493

End: 535750

Strand: Reverse

Name: infA

Synonym: ELI_02485

Alternate gene names: 85373324

Gene position: 535750-535493 (Counterclockwise)

Preceding gene: 85373326

Following gene: 85373323

Centisome position: 17.55

GC content: 62.79

Gene sequence:

>258_bases
ATGGCGAAAGAAGAACTCCTCGAAATGCGCGGCAAGGTAGTCGAGCTGCTGCCTAACGCGATGTTCCGGGTCGAGCTCGA
GAATGGTCATGAAGTCCTCGGACACACCGCCGGCAAGATGCGCAAGAACCGCATCCGCGTGCTGGTGGGCGACGAAGTGC
TGTGCGAATTGACGCCGTACGACCTGACCAAGGCGCGGATCACCTATCGCTTCATGCCGGGCCGTGGCGGCCCCGGCCAG
GGTCCCGGCCCGCAATAA

Upstream 100 bases:

>100_bases
ACAAAGCGCGGCACCTGCATTTCCGCGAAGGCTTCCCTTTTGCCCTGCGCCCCGCTAAAGCGCCGCCACCTTTTCAACAT
ATTTGGACTGTCGAGACTAC

Downstream 100 bases:

>100_bases
GGTACCCATGTCTCGACAGGCCATCTCGACATGCTCGATGGCCGCTCGACACGAACGGAAAACCTTATGAGTGCCGTTCC
TCCCGAGCAGCGATCGAGCG

Product: translation initiation factor IF-1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 85; Mature: 84

Protein sequence:

>85_residues
MAKEELLEMRGKVVELLPNAMFRVELENGHEVLGHTAGKMRKNRIRVLVGDEVLCELTPYDLTKARITYRFMPGRGGPGQ
GPGPQ

Sequences:

>Translated_85_residues
MAKEELLEMRGKVVELLPNAMFRVELENGHEVLGHTAGKMRKNRIRVLVGDEVLCELTPYDLTKARITYRFMPGRGGPGQ
GPGPQ
>Mature_84_residues
AKEELLEMRGKVVELLPNAMFRVELENGHEVLGHTAGKMRKNRIRVLVGDEVLCELTPYDLTKARITYRFMPGRGGPGQG
PGPQ

Specific function: No specific function has so far been attributed to this initiation factor; however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Escherichia coli, GI1787110, Length=70, Percent_Identity=67.1428571428571, Blast_Score=102, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1_ERYLH (Q2NCK2)

Other databases:

- EMBL:   CP000157
- RefSeq:   YP_457386.1
- ProteinModelPortal:   Q2NCK2
- SMR:   Q2NCK2
- STRING:   Q2NCK2
- GeneID:   3871549
- GenomeReviews:   CP000157_GR
- KEGG:   eli:ELI_02485
- NMPDR:   fig|314225.3.peg.2588
- eggNOG:   COG0361
- HOGENOM:   HBG286099
- OMA:   KMRMHFI
- ProtClustDB:   PRK00276
- BioCyc:   ELIT314225:ELI_02485-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00075
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR022967
- InterPro:   IPR006196
- InterPro:   IPR004368
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00316
- TIGRFAMs:   TIGR00008

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 9504; Mature: 9373

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
7.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKEELLEMRGKVVELLPNAMFRVELENGHEVLGHTAGKMRKNRIRVLVGDEVLCELTPY
CCHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCCEEEEEECCCEEEEECCC
DLTKARITYRFMPGRGGPGQGPGPQ
CCCEEEEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure 
AKEELLEMRGKVVELLPNAMFRVELENGHEVLGHTAGKMRKNRIRVLVGDEVLCELTPY
CHHHHHHHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCCCEEEEEECCCEEEEECCC
DLTKARITYRFMPGRGGPGQGPGPQ
CCCEEEEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA