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The map label for this gene is purQ [H]

Identifier: 85373315

GI number: 85373315

Start: 526513

End: 527184

Strand: Reverse

Name: purQ [H]

Synonym: ELI_02440

Alternate gene names: 85373315

Gene position: 527184-526513 (Counterclockwise)

Preceding gene: 85373316

Following gene: 85373310

Centisome position: 17.27

GC content: 66.67

Gene sequence:

>672_bases
ATGCGCACCGCCGTTATCACCTTTCCCGGCTCCAATTGCGATCGCGACATGGCGGTCGCGCTTGAACGGGCCAGCGGTAA
GGCCCCCTTGCGCGTCTGGCACGCCGACAAGGACCTGCCCGAACGGCTGGATTTCATCGCCCTGCCCGGCGGCTTTTCCT
ATGGCGACTACCTGCGCTCGGGCGCGATGGCGGCCAACAGCCCGATCATGCGCGCGGTCAAGCGAGAGGCCGATCGCGGC
GTTGCGGTGCTCGGCGTGTGCAACGGTTTTCAGGTTCTGGCCGAAAGCGGTCTGCTGCCCGGCGCCCTGATGCGCAACGC
GGCCCAGACCTTTATCTGCCGCACTGCGGCGCTCGAAGTGGTGACCAACCGGTCGCTGTTTACCTCGGGCTACGAAGCGG
GCCGGACCATTCACATTCCGGTCGCCCATCACGACGGCAATTATTTCGCCGATGCCGAAACGCTCGATCGGCTGGAGGGC
GAAGGCCGCGTGGCGTTCCGCTATCACGAGAATCCCAACGGCTCGCAGCGCGACATCGCCGGTATCCTCAATGCTGCCGG
CAACGTGCTGGGCATGATGCCGCACCCCGAACGCGCGGTGGATGCCGCGCATGGCGGCACCGACGGCCTGCCACTATTCA
AGGCGGCGCTGGAGCGGCTCGCGGCCGCCTGA

Upstream 100 bases:

>100_bases
CCGACGACACCAGCGATGCTTCGCTCACCGAGATGTGCGAGAAACTGCTCGCCAACACGGTGATCGAGAACTACCGCATC
GAGAAGGCGGACTGACGGCC

Downstream 100 bases:

>100_bases
CCGGGGGATTTGCAGCAGCCTGCCGCGTCAGGCGCGCAGACGGCCCGGCACGTCGAACAGCTTGCGGGCTTCGGCTTTGA
CCATGGGGCGCCCGAAGTAA

Product: phosphoribosylformylglycinamidine synthase I

Products: NA

Alternate protein names: Phosphoribosylformylglycinamidine synthase I; FGAM synthase I [H]

Number of amino acids: Translated: 223; Mature: 223

Protein sequence:

>223_residues
MRTAVITFPGSNCDRDMAVALERASGKAPLRVWHADKDLPERLDFIALPGGFSYGDYLRSGAMAANSPIMRAVKREADRG
VAVLGVCNGFQVLAESGLLPGALMRNAAQTFICRTAALEVVTNRSLFTSGYEAGRTIHIPVAHHDGNYFADAETLDRLEG
EGRVAFRYHENPNGSQRDIAGILNAAGNVLGMMPHPERAVDAAHGGTDGLPLFKAALERLAAA

Sequences:

>Translated_223_residues
MRTAVITFPGSNCDRDMAVALERASGKAPLRVWHADKDLPERLDFIALPGGFSYGDYLRSGAMAANSPIMRAVKREADRG
VAVLGVCNGFQVLAESGLLPGALMRNAAQTFICRTAALEVVTNRSLFTSGYEAGRTIHIPVAHHDGNYFADAETLDRLEG
EGRVAFRYHENPNGSQRDIAGILNAAGNVLGMMPHPERAVDAAHGGTDGLPLFKAALERLAAA
>Mature_223_residues
MRTAVITFPGSNCDRDMAVALERASGKAPLRVWHADKDLPERLDFIALPGGFSYGDYLRSGAMAANSPIMRAVKREADRG
VAVLGVCNGFQVLAESGLLPGALMRNAAQTFICRTAALEVVTNRSLFTSGYEAGRTIHIPVAHHDGNYFADAETLDRLEG
EGRVAFRYHENPNGSQRDIAGILNAAGNVLGMMPHPERAVDAAHGGTDGLPLFKAALERLAAA

Specific function: Unknown

COG id: COG0047

COG function: function code F; Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI31657129, Length=246, Percent_Identity=30.4878048780488, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI48994899, Length=226, Percent_Identity=34.9557522123894, Blast_Score=81, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6321498, Length=189, Percent_Identity=33.8624338624339, Blast_Score=84, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24582111, Length=239, Percent_Identity=32.6359832635983, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24582109, Length=239, Percent_Identity=32.6359832635983, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI17137292, Length=239, Percent_Identity=32.6359832635983, Blast_Score=90, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017926
- InterPro:   IPR011698
- InterPro:   IPR010075 [H]

Pfam domain/function: PF07685 GATase_3 [H]

EC number: =6.3.5.3 [H]

Molecular weight: Translated: 23815; Mature: 23815

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTAVITFPGSNCDRDMAVALERASGKAPLRVWHADKDLPERLDFIALPGGFSYGDYLRS
CCEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHCCEEECCCCCCHHHHHHC
GAMAANSPIMRAVKREADRGVAVLGVCNGFQVLAESGLLPGALMRNAAQTFICRTAALEV
CCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VTNRSLFTSGYEAGRTIHIPVAHHDGNYFADAETLDRLEGEGRVAFRYHENPNGSQRDIA
HHCCCHHHCCCCCCCEEEEEEEECCCCEEECHHHHHHHCCCCEEEEEEECCCCCCHHHHH
GILNAAGNVLGMMPHPERAVDAAHGGTDGLPLFKAALERLAAA
HHHHHCCCEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRTAVITFPGSNCDRDMAVALERASGKAPLRVWHADKDLPERLDFIALPGGFSYGDYLRS
CCEEEEEECCCCCCCHHHHHHHHCCCCCCEEEEECCCCCHHHCCEEECCCCCCHHHHHHC
GAMAANSPIMRAVKREADRGVAVLGVCNGFQVLAESGLLPGALMRNAAQTFICRTAALEV
CCCCCCCHHHHHHHHHHCCCEEEEEECCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VTNRSLFTSGYEAGRTIHIPVAHHDGNYFADAETLDRLEGEGRVAFRYHENPNGSQRDIA
HHCCCHHHCCCCCCCEEEEEEEECCCCEEECHHHHHHHCCCCEEEEEEECCCCCCHHHHH
GILNAAGNVLGMMPHPERAVDAAHGGTDGLPLFKAALERLAAA
HHHHHCCCEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA