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The map label for this gene is chvG [H]

Identifier: 85373253

GI number: 85373253

Start: 466916

End: 468505

Strand: Reverse

Name: chvG [H]

Synonym: ELI_02130

Alternate gene names: 85373253

Gene position: 468505-466916 (Counterclockwise)

Preceding gene: 85373254

Following gene: 85373252

Centisome position: 15.35

GC content: 66.29

Gene sequence:

>1590_bases
ATGGCTGAACGGCGCTTCGCCACCGACATCGTCCGCCCTCTCGAGCGCATGAGCGTGCTCGACCGGATATCGCTGACCGC
CCGCATCCTGCTGGTCAATATCCTGCCGCTCGCGGTGCTCGGTGGCGGCATTTTCTATCTCGACAGCTACCGTGCGCAAT
TGCTCGACGAGCGCTACAAGCTTGCCCGCATCGAAGCGCAGATCACCGCCGAAGCACTCGCCGGCGCAACGCGCGAGCGG
CAGGAGGCCCTGCTGGTCCAGATCGGCAAGGAGCAGCGCATGCGGCTGCGGATGTTCGATGCCGAGGGGCAATTGTGGGC
TGACAGCTTCGCGCTCGACGAACCGGGCTTCGCGTTCGATGATATTTCCGACGACACGTGGGAACAGCGATTTGCGCGCT
GGATCGACCGGGCCATCGACACGATTGTCAGCGCCGAACCGGTCACCGACTATATCGAGCCCGAATCGCAGCGGGCCGAT
GCCTGGCCCGAAGTCGTCCGCGCACGCGAACAGGGCCTCAGCCAGATCACGCTCTATGACTGGGTCGATGGCACTCCGGT
GATCACCGCCGCAGCGCCGGTCGGGCTCAACGGGGCGACGCTACTGACCACGCGCAATGCGGTAGACATTACCGAGGCGG
TGCGCTCGGCACGTACCTCGCTGCTGATCGGCGTCGGCTTCGCCCTCCTTGCATCGACGCTGCTGTCGCTGTTCCTCGCG
CGGACCATCGTCAAACCGCTGCAAATCCTCTCGCAATCGGCCCAGCGCGTCCGGCTCGGGCGCGAGCGCGATGTGGAAGT
GCCGCGCCTGCCGCACCGTCGCGACGAGATCGGCATGCTTGCGCGGGCCATCTCGGATATGACCGACGCACTGCGCCAGC
GCATCGATGCGGTCGAACATTTCGCCGCCGATGTCGCGCACGAGATCAAGAACCCGCTGGCCAGCCTGCGCAGTGCGACC
GAGTCATTGTCAAAGGTCGAGGACCCGGAGCTGCGCTCGCAATTGCTTGACATCGCGACGCATGACGTGCGCCGGATCGA
TCGCCTGGTGACGGAGATATCCGACGCCAGCCGGGTCGATGCGGAAATTTCGCGCGCAACCTTCGAGCGGGTGGATATGG
CCGCGCTGGTCGGCAATATCCTCGCGAGCCGGGAAAGCCGCGCCCTGAACGCCGGGCGCACGATCAACTTCGACCCGCCG
GCCCGCGCGGCCCGCGTGATGGGCGTGCCGGTGCGCCTCGAGCGCGTGATCGACAATCTGCTCGATAATGCGGTCTCGTT
CTCTCCGGAGGATGGGACGATCCAGATCGGCATGAGTGTGCAGGACGGCTGCGTCAGCCTGTCGATCTGCGACCATGGCC
CCGGCATACCGGAAGCGGAGCGCGGGAAGATCTTCGACCGCTTTCATTCCGTCCGGCCCGAGGCCGAGGACTTCGGCAAC
CACAGCGGGCTGGGCCTCGCCATTGCGCGGACCATCGCCGAAGCGCACGGCGGCTCCCTGCTCGCAGACGATCGGCCCGA
CGGGCAACAGGGCGCCTGCCTCACGCTGTCGCTGCCCGAAGCGCGGACCAGTTCAACCGGTGCGCCCTGA

Upstream 100 bases:

>100_bases
GTCGACAGCCACATCAAGCGCATGCGGCGCAAGTTCCGCAGCGTCGACAGGGAGTTCGGGGCGATCGAAACGCTTTACGG
CGCGGGATACAGTTTCTCAG

Downstream 100 bases:

>100_bases
TGCTCTACCAGGCGAGCTGCGTCGCCATCGGCGGCCGGGCTGTCCTTATCGAAGGGCCACCGGGGGCGGGCAAGACCTCG
CTGGCCCTCGCGCTAATCGA

Product: two-component signal transduction histidine kinase

Products: NA

Alternate protein names: Histidine kinase sensory protein ExoS [H]

Number of amino acids: Translated: 529; Mature: 528

Protein sequence:

>529_residues
MAERRFATDIVRPLERMSVLDRISLTARILLVNILPLAVLGGGIFYLDSYRAQLLDERYKLARIEAQITAEALAGATRER
QEALLVQIGKEQRMRLRMFDAEGQLWADSFALDEPGFAFDDISDDTWEQRFARWIDRAIDTIVSAEPVTDYIEPESQRAD
AWPEVVRAREQGLSQITLYDWVDGTPVITAAAPVGLNGATLLTTRNAVDITEAVRSARTSLLIGVGFALLASTLLSLFLA
RTIVKPLQILSQSAQRVRLGRERDVEVPRLPHRRDEIGMLARAISDMTDALRQRIDAVEHFAADVAHEIKNPLASLRSAT
ESLSKVEDPELRSQLLDIATHDVRRIDRLVTEISDASRVDAEISRATFERVDMAALVGNILASRESRALNAGRTINFDPP
ARAARVMGVPVRLERVIDNLLDNAVSFSPEDGTIQIGMSVQDGCVSLSICDHGPGIPEAERGKIFDRFHSVRPEAEDFGN
HSGLGLAIARTIAEAHGGSLLADDRPDGQQGACLTLSLPEARTSSTGAP

Sequences:

>Translated_529_residues
MAERRFATDIVRPLERMSVLDRISLTARILLVNILPLAVLGGGIFYLDSYRAQLLDERYKLARIEAQITAEALAGATRER
QEALLVQIGKEQRMRLRMFDAEGQLWADSFALDEPGFAFDDISDDTWEQRFARWIDRAIDTIVSAEPVTDYIEPESQRAD
AWPEVVRAREQGLSQITLYDWVDGTPVITAAAPVGLNGATLLTTRNAVDITEAVRSARTSLLIGVGFALLASTLLSLFLA
RTIVKPLQILSQSAQRVRLGRERDVEVPRLPHRRDEIGMLARAISDMTDALRQRIDAVEHFAADVAHEIKNPLASLRSAT
ESLSKVEDPELRSQLLDIATHDVRRIDRLVTEISDASRVDAEISRATFERVDMAALVGNILASRESRALNAGRTINFDPP
ARAARVMGVPVRLERVIDNLLDNAVSFSPEDGTIQIGMSVQDGCVSLSICDHGPGIPEAERGKIFDRFHSVRPEAEDFGN
HSGLGLAIARTIAEAHGGSLLADDRPDGQQGACLTLSLPEARTSSTGAP
>Mature_528_residues
AERRFATDIVRPLERMSVLDRISLTARILLVNILPLAVLGGGIFYLDSYRAQLLDERYKLARIEAQITAEALAGATRERQ
EALLVQIGKEQRMRLRMFDAEGQLWADSFALDEPGFAFDDISDDTWEQRFARWIDRAIDTIVSAEPVTDYIEPESQRADA
WPEVVRAREQGLSQITLYDWVDGTPVITAAAPVGLNGATLLTTRNAVDITEAVRSARTSLLIGVGFALLASTLLSLFLAR
TIVKPLQILSQSAQRVRLGRERDVEVPRLPHRRDEIGMLARAISDMTDALRQRIDAVEHFAADVAHEIKNPLASLRSATE
SLSKVEDPELRSQLLDIATHDVRRIDRLVTEISDASRVDAEISRATFERVDMAALVGNILASRESRALNAGRTINFDPPA
RAARVMGVPVRLERVIDNLLDNAVSFSPEDGTIQIGMSVQDGCVSLSICDHGPGIPEAERGKIFDRFHSVRPEAEDFGNH
SGLGLAIARTIAEAHGGSLLADDRPDGQQGACLTLSLPEARTSSTGAP

Specific function: Member of a two-component regulatory system ChvG(ExoS)/ChvI involved in regulating the production of succinoglycan. Activates ChvI by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=444, Percent_Identity=27.9279279279279, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1790861, Length=242, Percent_Identity=30.5785123966942, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082128, Length=301, Percent_Identity=27.2425249169435, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786912, Length=222, Percent_Identity=32.4324324324324, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790346, Length=296, Percent_Identity=26.0135135135135, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=226, Percent_Identity=26.9911504424779, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790551, Length=310, Percent_Identity=29.0322580645161, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788279, Length=283, Percent_Identity=27.9151943462898, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=26.2008733624454, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI1786600, Length=238, Percent_Identity=26.890756302521, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI145693157, Length=244, Percent_Identity=26.2295081967213, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787894, Length=241, Percent_Identity=27.8008298755187, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1788549, Length=279, Percent_Identity=27.2401433691756, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI1789808, Length=325, Percent_Identity=24, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788713, Length=235, Percent_Identity=25.9574468085106, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789403, Length=204, Percent_Identity=29.9019607843137, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87081816, Length=343, Percent_Identity=28.5714285714286, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1789149, Length=218, Percent_Identity=24.7706422018349, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI48994928, Length=270, Percent_Identity=21.4814814814815, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58119; Mature: 57987

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAERRFATDIVRPLERMSVLDRISLTARILLVNILPLAVLGGGIFYLDSYRAQLLDERYK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LARIEAQITAEALAGATRERQEALLVQIGKEQRMRLRMFDAEGQLWADSFALDEPGFAFD
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHEEEEECCCCCEECCCCCCCCCCCCCC
DISDDTWEQRFARWIDRAIDTIVSAEPVTDYIEPESQRADAWPEVVRAREQGLSQITLYD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEE
WVDGTPVITAAAPVGLNGATLLTTRNAVDITEAVRSARTSLLIGVGFALLASTLLSLFLA
CCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTIVKPLQILSQSAQRVRLGRERDVEVPRLPHRRDEIGMLARAISDMTDALRQRIDAVEH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAADVAHEIKNPLASLRSATESLSKVEDPELRSQLLDIATHDVRRIDRLVTEISDASRVD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEISRATFERVDMAALVGNILASRESRALNAGRTINFDPPARAARVMGVPVRLERVIDNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHCCCHHHHHHHHHH
LDNAVSFSPEDGTIQIGMSVQDGCVSLSICDHGPGIPEAERGKIFDRFHSVRPEAEDFGN
HHHHCCCCCCCCEEEEECEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHCCC
HSGLGLAIARTIAEAHGGSLLADDRPDGQQGACLTLSLPEARTSSTGAP
CCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
AERRFATDIVRPLERMSVLDRISLTARILLVNILPLAVLGGGIFYLDSYRAQLLDERYK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
LARIEAQITAEALAGATRERQEALLVQIGKEQRMRLRMFDAEGQLWADSFALDEPGFAFD
HHHHHHHHHHHHHHCCHHHHHHHHHHHHCHHHHHEEEEECCCCCEECCCCCCCCCCCCCC
DISDDTWEQRFARWIDRAIDTIVSAEPVTDYIEPESQRADAWPEVVRAREQGLSQITLYD
CCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCCCHHHHHHHHCCCCEEEEEE
WVDGTPVITAAAPVGLNGATLLTTRNAVDITEAVRSARTSLLIGVGFALLASTLLSLFLA
CCCCCCEEEECCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTIVKPLQILSQSAQRVRLGRERDVEVPRLPHRRDEIGMLARAISDMTDALRQRIDAVEH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FAADVAHEIKNPLASLRSATESLSKVEDPELRSQLLDIATHDVRRIDRLVTEISDASRVD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AEISRATFERVDMAALVGNILASRESRALNAGRTINFDPPARAARVMGVPVRLERVIDNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCHHHHHHHCCCHHHHHHHHHH
LDNAVSFSPEDGTIQIGMSVQDGCVSLSICDHGPGIPEAERGKIFDRFHSVRPEAEDFGN
HHHHCCCCCCCCEEEEECEECCCCEEEEEECCCCCCCCCCCCHHHHHHHHCCCCHHHCCC
HSGLGLAIARTIAEAHGGSLLADDRPDGQQGACLTLSLPEARTSSTGAP
CCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9422587; 11481430; 7559334 [H]