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The map label for this gene is rkpK [H]

Identifier: 85373070

GI number: 85373070

Start: 282804

End: 284114

Strand: Reverse

Name: rkpK [H]

Synonym: ELI_01215

Alternate gene names: 85373070

Gene position: 284114-282804 (Counterclockwise)

Preceding gene: 85373071

Following gene: 85373068

Centisome position: 9.31

GC content: 61.48

Gene sequence:

>1311_bases
ATGAAAATCGCAATGGTGGGATCCGGCTACGTCGGCCTGGTTTCCGGTGCATGCTTTGCCGATTTCGGCCACGACGTTGT
CTGCATCGACAAGGACCAGTCCAAGATCGACCGCCTGCATGATGGCATCATGCCGATCTACGAGCCGGGGCTCGATGCGC
TGGTCGATGCGAATGTCAAAGCCGGTCGGCTCAGCTTCACTACAGACCTCGGCGAAGGGATCGAGGGCGCAAAGGCGATC
TTCATTGCCGTCGGCACGCCAAGCCGCCGCGGCGACGGGCACGCCGATCTCACCTTCGTTCACGAAGTCGCGCGCGAAGT
GGGCAAGAACCTCGCCAACGATGCGGTCATCGTGACAAAGTCCACCGTCCCGGTCGGCACCGGAGACGAAGTCGAACGCA
TTATCGCCGACGCCGGGACAAAGCATCGCTTCGCCGTTGTTTCCAACCCCGAGTTCCTGCGCGAAGGTGCCGCAATCGGC
GACTTCAAGCGCCCCGACCGTATCGTGATCGGTACCGAAGACGATTTCGGCCGCGAGATCATGACGGAGGTCTATCGCCC
GCTCTATCTGAACGAATCTCCGATCCTTTTCACCAGCCGCCGATCGAGCGAGCTGATCAAGTATGCCGCCAATGCGTTTC
TCGCGACCAAGATCACCTTCATCAACGAAATGGCGGATCTGTGCGAAAAGGTCGGCGGCAATGTCCAGGACGTGGCGCGC
GGGATCGGGATGGACGGCCGCATCGGCCCCAAGTTCCTCAATGCCGGCCCAGGGTATGGCGGCTCCTGCTTCCCCAAGGA
CACGCTGGCCTTGCTGAAGACGGCCGAAGATTATGACAGTCCGGTGCGGATCATCGAGGCGGTGGTCAAGACCAACGAAA
GTCGCAAGCGCGCGATGGGCCGCAAGGTTATCGATGCGCTCGGTGGAATGGATGCAGCCCGCGGCAAAAAGGTCGCGCTG
CTGGGCCTGACGTTCAAGCCCAACACCGATGACATGCGCGACAGCCCGGCTATCGCAATCGCCCAGACGCTGACCGATGC
CGGCGTCAACGTCGTCGCATACGATCCGGAAGGCATGGAGATCGCCAAGCCGCTGATGCCCGAGGTTGCTATGGCAGAGA
ACTCTTATGAGGCAATCGAAGGCGCCGATGCGGTGGTCATCGTGACCGAATGGGACGCCTTCCGCGCGCTCGACCTCGAT
CGGGTCAAGGAGCTGGCGGCAGCACCGGTGCTCGTCGACTTGCGCAACATCTACGCACCGTCCGATGTTCGCGCGAAGGG
CTTCGACTACGTCAGCATCGGACGGGTCTGA

Upstream 100 bases:

>100_bases
GGCGACTAACCGCGCTGGTGCTGGAAGAAAACCGGCGGCGCATGATTCAGGCCGTGGACGACAACGGCACAATCAGGATC
GAAAAAAGGGACAGCTTGGT

Downstream 100 bases:

>100_bases
GGATTAGCCGAACCAACGGCGTCGGCTCTCCGCATCGCGCAGGCCGACTATCGCTGCACCGATGACCAGCAGGCCGGCGA
TGATGCAGGCGAGTGCTATG

Product: hypothetical protein

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 436; Mature: 436

Protein sequence:

>436_residues
MKIAMVGSGYVGLVSGACFADFGHDVVCIDKDQSKIDRLHDGIMPIYEPGLDALVDANVKAGRLSFTTDLGEGIEGAKAI
FIAVGTPSRRGDGHADLTFVHEVAREVGKNLANDAVIVTKSTVPVGTGDEVERIIADAGTKHRFAVVSNPEFLREGAAIG
DFKRPDRIVIGTEDDFGREIMTEVYRPLYLNESPILFTSRRSSELIKYAANAFLATKITFINEMADLCEKVGGNVQDVAR
GIGMDGRIGPKFLNAGPGYGGSCFPKDTLALLKTAEDYDSPVRIIEAVVKTNESRKRAMGRKVIDALGGMDAARGKKVAL
LGLTFKPNTDDMRDSPAIAIAQTLTDAGVNVVAYDPEGMEIAKPLMPEVAMAENSYEAIEGADAVVIVTEWDAFRALDLD
RVKELAAAPVLVDLRNIYAPSDVRAKGFDYVSIGRV

Sequences:

>Translated_436_residues
MKIAMVGSGYVGLVSGACFADFGHDVVCIDKDQSKIDRLHDGIMPIYEPGLDALVDANVKAGRLSFTTDLGEGIEGAKAI
FIAVGTPSRRGDGHADLTFVHEVAREVGKNLANDAVIVTKSTVPVGTGDEVERIIADAGTKHRFAVVSNPEFLREGAAIG
DFKRPDRIVIGTEDDFGREIMTEVYRPLYLNESPILFTSRRSSELIKYAANAFLATKITFINEMADLCEKVGGNVQDVAR
GIGMDGRIGPKFLNAGPGYGGSCFPKDTLALLKTAEDYDSPVRIIEAVVKTNESRKRAMGRKVIDALGGMDAARGKKVAL
LGLTFKPNTDDMRDSPAIAIAQTLTDAGVNVVAYDPEGMEIAKPLMPEVAMAENSYEAIEGADAVVIVTEWDAFRALDLD
RVKELAAAPVLVDLRNIYAPSDVRAKGFDYVSIGRV
>Mature_436_residues
MKIAMVGSGYVGLVSGACFADFGHDVVCIDKDQSKIDRLHDGIMPIYEPGLDALVDANVKAGRLSFTTDLGEGIEGAKAI
FIAVGTPSRRGDGHADLTFVHEVAREVGKNLANDAVIVTKSTVPVGTGDEVERIIADAGTKHRFAVVSNPEFLREGAAIG
DFKRPDRIVIGTEDDFGREIMTEVYRPLYLNESPILFTSRRSSELIKYAANAFLATKITFINEMADLCEKVGGNVQDVAR
GIGMDGRIGPKFLNAGPGYGGSCFPKDTLALLKTAEDYDSPVRIIEAVVKTNESRKRAMGRKVIDALGGMDAARGKKVAL
LGLTFKPNTDDMRDSPAIAIAQTLTDAGVNVVAYDPEGMEIAKPLMPEVAMAENSYEAIEGADAVVIVTEWDAFRALDLD
RVKELAAAPVLVDLRNIYAPSDVRAKGFDYVSIGRV

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=463, Percent_Identity=36.9330453563715, Blast_Score=277, Evalue=2e-74,
Organism=Homo sapiens, GI296040438, Length=365, Percent_Identity=38.3561643835616, Blast_Score=229, Evalue=4e-60,
Organism=Homo sapiens, GI296040443, Length=457, Percent_Identity=32.6039387308534, Blast_Score=222, Evalue=5e-58,
Organism=Escherichia coli, GI1788340, Length=360, Percent_Identity=31.9444444444444, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI48994968, Length=419, Percent_Identity=28.8782816229117, Blast_Score=153, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17560350, Length=463, Percent_Identity=35.4211663066955, Blast_Score=251, Evalue=4e-67,
Organism=Drosophila melanogaster, GI17136908, Length=463, Percent_Identity=36.7170626349892, Blast_Score=271, Evalue=8e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 46833; Mature: 46833

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAMVGSGYVGLVSGACFADFGHDVVCIDKDQSKIDRLHDGIMPIYEPGLDALVDANVK
CEEEEECCCCHHHHCCCHHHHCCCCEEEEECCHHHHHHHHCCCCCHHCCCCHHHCCCCCC
AGRLSFTTDLGEGIEGAKAIFIAVGTPSRRGDGHADLTFVHEVAREVGKNLANDAVIVTK
CCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
STVPVGTGDEVERIIADAGTKHRFAVVSNPEFLREGAAIGDFKRPDRIVIGTEDDFGREI
CCCCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHCCCCCCCCCCCCEEEEECCCHHHHHH
MTEVYRPLYLNESPILFTSRRSSELIKYAANAFLATKITFINEMADLCEKVGGNVQDVAR
HHHHHCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GIGMDGRIGPKFLNAGPGYGGSCFPKDTLALLKTAEDYDSPVRIIEAVVKTNESRKRAMG
HCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHH
RKVIDALGGMDAARGKKVALLGLTFKPNTDDMRDSPAIAIAQTLTDAGVNVVAYDPEGME
HHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCH
IAKPLMPEVAMAENSYEAIEGADAVVIVTEWDAFRALDLDRVKELAAAPVLVDLRNIYAP
HHHHHCCHHHHCCCCHHHHCCCCEEEEEEECCCHHHCCHHHHHHHHHCCHHEEHHHHCCC
SDVRAKGFDYVSIGRV
CCCCCCCCCEEEECCC
>Mature Secondary Structure
MKIAMVGSGYVGLVSGACFADFGHDVVCIDKDQSKIDRLHDGIMPIYEPGLDALVDANVK
CEEEEECCCCHHHHCCCHHHHCCCCEEEEECCHHHHHHHHCCCCCHHCCCCHHHCCCCCC
AGRLSFTTDLGEGIEGAKAIFIAVGTPSRRGDGHADLTFVHEVAREVGKNLANDAVIVTK
CCEEEEECCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEE
STVPVGTGDEVERIIADAGTKHRFAVVSNPEFLREGAAIGDFKRPDRIVIGTEDDFGREI
CCCCCCCCHHHHHHHHCCCCCCEEEEECCHHHHHCCCCCCCCCCCCEEEEECCCHHHHHH
MTEVYRPLYLNESPILFTSRRSSELIKYAANAFLATKITFINEMADLCEKVGGNVQDVAR
HHHHHCCEEECCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GIGMDGRIGPKFLNAGPGYGGSCFPKDTLALLKTAEDYDSPVRIIEAVVKTNESRKRAMG
HCCCCCCCCCHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHH
RKVIDALGGMDAARGKKVALLGLTFKPNTDDMRDSPAIAIAQTLTDAGVNVVAYDPEGME
HHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCH
IAKPLMPEVAMAENSYEAIEGADAVVIVTEWDAFRALDLDRVKELAAAPVLVDLRNIYAP
HHHHHCCHHHHCCCCHHHHCCCCEEEEEEECCCHHHCCHHHHHHHHHCCHHEEHHHHCCC
SDVRAKGFDYVSIGRV
CCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9765575; 11481430 [H]