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The map label for this gene is engA

Identifier: 85373044

GI number: 85373044

Start: 253268

End: 254725

Strand: Reverse

Name: engA

Synonym: ELI_01085

Alternate gene names: 85373044

Gene position: 254725-253268 (Counterclockwise)

Preceding gene: 85373046

Following gene: 85373043

Centisome position: 8.35

GC content: 65.91

Gene sequence:

>1458_bases
ATGCCTCACCACCTCAAGCCGACCGTCATCATCATAGGCCGCCCCAATGTCGGCAAGTCGACGCTGTTCAACCGGCTTGT
CGGCAAGAAGCTCGCGCTGGTCGACGACCAGCCGGGCGTGACGCGCGACCGCCGCATGGGCGATGCCGAACTGGCGGGCA
TGGAGTTCACGGTCGTCGATACCGCCGGCTGGGAAGACGACGACAAGGACAGCCTGCCCGGGCGGATGCGCGCGCAGACC
GAAGTCAGTCTCGAAGGCGCCGATGCCGCGCTGTTCGTTATCGACGCCCGCGCCGGGATCACCCCGCTCGATGAAGAGAT
CGCCCGCTGGCTGCGCACGGTCGAGGTGCCGGTGGTGCTCGTCGCCAACAAGGCCGAAGGCAAGGCAGGCGATGCCGGCC
TGCTCGAATCCTATGCGCTCGGTCTCGGCGATCCCGCCCCGGTATCCGCCGAGCACGGCGAAGGCATTGCCGACTTGTTC
GAAGGTCTGTGGCCCCATATCGGCCATTTCGAGAAGGACGCCGAACGCGCCGCTGCCGAGGCTGCGGAAGTCGGCGAGGG
CGATGAGGACGACGAAGATGCGCCGCTCGGCCCGCTCAAGCTCGCCATCGTCGGTCGTCCCAATGCCGGCAAGTCGACGC
TGATCAATCGCTTGCTGGGCGAGGACCGCCTTCTCACCGGCCCGGAAGCAGGGATCACGCGCGATTCCATCTCGGTCGAC
TGGCAATGGACCGACCCAAAGTCCGGCGAGCCTCGCGACATCCGCCTGATCGACACTGCCGGCATGCGCAAGCGCGCCAG
GGTGACCGAGAAGCTGGAGAAGCTCTCCGTTGCCGATGCCTTCCGCGCGGTGGACTTTGCCGAAGTCGTTGTCCTGCTGC
TCGATGCGACGCAGGGGCTGGAGCATCAGGATCTCAAGATCGCCAGCAAGGTGCTGGAAGAAGGCCGCGCGCTGATGATC
GCGATCAACAAGTGGGACATTGCCGAAGACGCTTCCTACCTTTTCAACGGCATCCGCGCCGCGCTCGACGAAGGGCTTAG
CCAAGTGCGCGGATTGCCGCTGTTCGCGGTCAGCGCCAAGACCGGCAAGGGTCTCGACGAGATGCTGCGCGCCGCGTTCG
AGATCCGCGAAAGCTGGTCCAAGCGCGTGCCGACCGCTGCGCTCAACCGCTGGTTCGACGATGCGCTGGACGCCAATCCC
CCCCCTGCACCCGGTGGCCGCCGTATCAAGCTGCGCTACATCACGCAGGCCGGTACCCGCCCGCCGCGATTCGTCGTGTT
CGGCACGCGGCTCGAAGCGCTGCCCAAGAGTTACGAGCGCTACCTCGTCAACGGCATCAGGGCGAAGCTCGGCTTCGAAG
CGGTCCCGGTGCGGGTCGTGCTCAAGAGCCCCAAGAACCCCTATAATGCCAACCGGGGTGGCGGCGGCAATTACAGTACC
GGATCGGATCGCGGCTGA

Upstream 100 bases:

>100_bases
CAACCTTACGATGGGCCTTGAGAGTGTGGTAAACCGAAATTTACCATACACGACATCTCACTTGCCAAGCGCCCGCGAAG
CGACCACCTGCGCCTCCATC

Downstream 100 bases:

>100_bases
TGCTTTGGGACATGCTTGCCGCGACCGGCGGAAACATCGCCAGCGATCTGCTGGAGCGCACGTCCAGCACTTTGCGCGTA
CAGGAAATCGTTCGTCTGAG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MPHHLKPTVIIIGRPNVGKSTLFNRLVGKKLALVDDQPGVTRDRRMGDAELAGMEFTVVDTAGWEDDDKDSLPGRMRAQT
EVSLEGADAALFVIDARAGITPLDEEIARWLRTVEVPVVLVANKAEGKAGDAGLLESYALGLGDPAPVSAEHGEGIADLF
EGLWPHIGHFEKDAERAAAEAAEVGEGDEDDEDAPLGPLKLAIVGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVD
WQWTDPKSGEPRDIRLIDTAGMRKRARVTEKLEKLSVADAFRAVDFAEVVVLLLDATQGLEHQDLKIASKVLEEGRALMI
AINKWDIAEDASYLFNGIRAALDEGLSQVRGLPLFAVSAKTGKGLDEMLRAAFEIRESWSKRVPTAALNRWFDDALDANP
PPAPGGRRIKLRYITQAGTRPPRFVVFGTRLEALPKSYERYLVNGIRAKLGFEAVPVRVVLKSPKNPYNANRGGGGNYST
GSDRG

Sequences:

>Translated_485_residues
MPHHLKPTVIIIGRPNVGKSTLFNRLVGKKLALVDDQPGVTRDRRMGDAELAGMEFTVVDTAGWEDDDKDSLPGRMRAQT
EVSLEGADAALFVIDARAGITPLDEEIARWLRTVEVPVVLVANKAEGKAGDAGLLESYALGLGDPAPVSAEHGEGIADLF
EGLWPHIGHFEKDAERAAAEAAEVGEGDEDDEDAPLGPLKLAIVGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVD
WQWTDPKSGEPRDIRLIDTAGMRKRARVTEKLEKLSVADAFRAVDFAEVVVLLLDATQGLEHQDLKIASKVLEEGRALMI
AINKWDIAEDASYLFNGIRAALDEGLSQVRGLPLFAVSAKTGKGLDEMLRAAFEIRESWSKRVPTAALNRWFDDALDANP
PPAPGGRRIKLRYITQAGTRPPRFVVFGTRLEALPKSYERYLVNGIRAKLGFEAVPVRVVLKSPKNPYNANRGGGGNYST
GSDRG
>Mature_484_residues
PHHLKPTVIIIGRPNVGKSTLFNRLVGKKLALVDDQPGVTRDRRMGDAELAGMEFTVVDTAGWEDDDKDSLPGRMRAQTE
VSLEGADAALFVIDARAGITPLDEEIARWLRTVEVPVVLVANKAEGKAGDAGLLESYALGLGDPAPVSAEHGEGIADLFE
GLWPHIGHFEKDAERAAAEAAEVGEGDEDDEDAPLGPLKLAIVGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVDW
QWTDPKSGEPRDIRLIDTAGMRKRARVTEKLEKLSVADAFRAVDFAEVVVLLLDATQGLEHQDLKIASKVLEEGRALMIA
INKWDIAEDASYLFNGIRAALDEGLSQVRGLPLFAVSAKTGKGLDEMLRAAFEIRESWSKRVPTAALNRWFDDALDANPP
PAPGGRRIKLRYITQAGTRPPRFVVFGTRLEALPKSYERYLVNGIRAKLGFEAVPVRVVLKSPKNPYNANRGGGGNYSTG
SDRG

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=479, Percent_Identity=41.1273486430063, Blast_Score=337, Evalue=1e-93,
Organism=Escherichia coli, GI1788919, Length=174, Percent_Identity=29.8850574712644, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI2367268, Length=173, Percent_Identity=35.2601156069364, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 52610; Mature: 52479

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHHLKPTVIIIGRPNVGKSTLFNRLVGKKLALVDDQPGVTRDRRMGDAELAGMEFTVVD
CCCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCCHHHCCCCHHHCCEEEEEEE
TAGWEDDDKDSLPGRMRAQTEVSLEGADAALFVIDARAGITPLDEEIARWLRTVEVPVVL
CCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEE
VANKAEGKAGDAGLLESYALGLGDPAPVSAEHGEGIADLFEGLWPHIGHFEKDAERAAAE
EEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
AAEVGEGDEDDEDAPLGPLKLAIVGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVD
HHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEE
WQWTDPKSGEPRDIRLIDTAGMRKRARVTEKLEKLSVADAFRAVDFAEVVVLLLDATQGL
EEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EHQDLKIASKVLEEGRALMIAINKWDIAEDASYLFNGIRAALDEGLSQVRGLPLFAVSAK
CHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
TGKGLDEMLRAAFEIRESWSKRVPTAALNRWFDDALDANPPPAPGGRRIKLRYITQAGTR
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCC
PPRFVVFGTRLEALPKSYERYLVNGIRAKLGFEAVPVRVVLKSPKNPYNANRGGGGNYST
CCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
GSDRG
CCCCC
>Mature Secondary Structure 
PHHLKPTVIIIGRPNVGKSTLFNRLVGKKLALVDDQPGVTRDRRMGDAELAGMEFTVVD
CCCCCCEEEEEECCCCCHHHHHHHHHCCEEEEECCCCCCCHHHCCCCHHHCCEEEEEEE
TAGWEDDDKDSLPGRMRAQTEVSLEGADAALFVIDARAGITPLDEEIARWLRTVEVPVVL
CCCCCCCCCCCCCCCCCCCEEEEECCCCEEEEEEECCCCCCCCHHHHHHHHHHHCCCEEE
VANKAEGKAGDAGLLESYALGLGDPAPVSAEHGEGIADLFEGLWPHIGHFEKDAERAAAE
EEECCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHH
AAEVGEGDEDDEDAPLGPLKLAIVGRPNAGKSTLINRLLGEDRLLTGPEAGITRDSISVD
HHHCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCEECCCCCCCCCCCEEEE
WQWTDPKSGEPRDIRLIDTAGMRKRARVTEKLEKLSVADAFRAVDFAEVVVLLLDATQGL
EEECCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
EHQDLKIASKVLEEGRALMIAINKWDIAEDASYLFNGIRAALDEGLSQVRGLPLFAVSAK
CHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
TGKGLDEMLRAAFEIRESWSKRVPTAALNRWFDDALDANPPPAPGGRRIKLRYITQAGTR
CCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCCC
PPRFVVFGTRLEALPKSYERYLVNGIRAKLGFEAVPVRVVLKSPKNPYNANRGGGGNYST
CCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCCCC
GSDRG
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA