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The map label for this gene is yoeA [H]

Identifier: 85372902

GI number: 85372902

Start: 100723

End: 102075

Strand: Reverse

Name: yoeA [H]

Synonym: ELI_00375

Alternate gene names: 85372902

Gene position: 102075-100723 (Counterclockwise)

Preceding gene: 85372904

Following gene: 85372901

Centisome position: 3.34

GC content: 63.78

Gene sequence:

>1353_bases
ATGAGCGAGAATGCCAAGCTGACGCGGGGGAGTATTCCCGGCCATCTCGTATCGCAGACCCTGCCCATGATCATCGGCGT
CGCAGCCATCATGTCGATCGGCCTTGTCGATGCCTATTTCATCGGCCAACTCGGCAGCGAACAGCTTGCGGCGATCAGCT
TCATCTTCCCGATCACAGTCGCGATCACCAGTCTCGGCGTCGGCATTATGGTCGGCATCAATTCGGTCGTCGCCCGGGCG
CTCGGCGAAGGCGACGACGACATGGCGGCGAGGCGCGCCAACTTCGGGATCGTATTCGCGATCGGCTGCGGTCTGGTGTT
CGCGATCTCGTTGTTCGTGCTGCTCGATCCGCTGTTCCGGTTGATGAACGCGGAAGATGCTCTCCTTCCCTTCATCCAGA
CCTATATGCGGCCCTACCTGATGGGCTTTCCGTTACTGCTCGCCATTATGGGTTTCAATGGCGTGCTGCGGGGCCAGGGC
GAGGCGCGCAAGACGAGTTATGTCTCGCTCACATACGCCGCCGCCAACTGGGTGCTCGACCCGCTCCTCATTACCGGAGC
GTTCGGCTTCGAGGGGTTCGGCATTGCCGGGGCGGCCTATGCGACGGTCATAGGCTGGCTCCTGGGCGTCGGCATGGCGT
GGTGGCTGATGCGCGGGACGCCGCTGCCGGTCGATTTCGGCCTGCTCAGGCGCTGTAGCCTGACCGAGCCGATGAAGGCG
ATAACGCGCGTGGCAGGGCCCGCAGCTTTTTCCAACGCGATCAACCCGATCGGCCTGTCGGTGCTGACCGCGCTGGTTGC
CGTCGAAGGCCAGGCGGCGGTTGCGGGGTTCGGCGCCGCGGGTCGCTTGCAGAGTTTCGCGGTGGTACCGCTGCTCGGCC
TCTCCGGCTCCATCGGCGCAATCGTCGGTCAGAACTGGGGCGCCCACCAGAGGGACCGTGCCAAGCAGGCGACACTTTAC
GCCGGTGGGTTCTGCATCGTCTGGGGCCTTTCCATCGCCGTCGCGCTCTTTGCGGCGGGCGAGTGGTTCGCGGGCTTCTT
CACCGACGACCCTGCGGTCGTCGATGAATTTGCACGCTATCTCACCATCGCGGCCTGGGGTTACGCAGGATATGGCCTGC
TGATCGTTGGCAACGGAATATTGAACGCGGTCGACAGGGCTGGCTGGGCGCTCGCGCAGAGCTGTTTTCGCGTATTCGCG
GTGATGGTGCCGTTCGCCTGGCTGTTGCGCGGAAGCTGGGGGTCGGATGCTATTTACGGAGCCGAACTGGCTGCCAATCT
CGTAGGCGGCGCCGTTGCCATGGCGCTCGTCTGGTGGATCCTCAATCGCAAACCCGCCGGCCAAACGGCATGA

Upstream 100 bases:

>100_bases
CGCTGTCTAAGCCAAATTCGATAGCCAGCGCAAAGCCGTCGAGCGCGCTATCCGGCATTTTCGCTTCCCCCTGACCCACC
CCGCAGCTAGGCGAGACGCC

Downstream 100 bases:

>100_bases
GCCAGCCAAGCCTGTATATCTTCTGCCGCTGGCCTGCGCCGGGCAAGGCCAAGACGCGGCTCATCCCGCGCTTCGGCGAG
GCTGGGGCCGCCGCGATCTA

Product: Na(+) driven multidrug efflux pump

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 450; Mature: 449

Protein sequence:

>450_residues
MSENAKLTRGSIPGHLVSQTLPMIIGVAAIMSIGLVDAYFIGQLGSEQLAAISFIFPITVAITSLGVGIMVGINSVVARA
LGEGDDDMAARRANFGIVFAIGCGLVFAISLFVLLDPLFRLMNAEDALLPFIQTYMRPYLMGFPLLLAIMGFNGVLRGQG
EARKTSYVSLTYAAANWVLDPLLITGAFGFEGFGIAGAAYATVIGWLLGVGMAWWLMRGTPLPVDFGLLRRCSLTEPMKA
ITRVAGPAAFSNAINPIGLSVLTALVAVEGQAAVAGFGAAGRLQSFAVVPLLGLSGSIGAIVGQNWGAHQRDRAKQATLY
AGGFCIVWGLSIAVALFAAGEWFAGFFTDDPAVVDEFARYLTIAAWGYAGYGLLIVGNGILNAVDRAGWALAQSCFRVFA
VMVPFAWLLRGSWGSDAIYGAELAANLVGGAVAMALVWWILNRKPAGQTA

Sequences:

>Translated_450_residues
MSENAKLTRGSIPGHLVSQTLPMIIGVAAIMSIGLVDAYFIGQLGSEQLAAISFIFPITVAITSLGVGIMVGINSVVARA
LGEGDDDMAARRANFGIVFAIGCGLVFAISLFVLLDPLFRLMNAEDALLPFIQTYMRPYLMGFPLLLAIMGFNGVLRGQG
EARKTSYVSLTYAAANWVLDPLLITGAFGFEGFGIAGAAYATVIGWLLGVGMAWWLMRGTPLPVDFGLLRRCSLTEPMKA
ITRVAGPAAFSNAINPIGLSVLTALVAVEGQAAVAGFGAAGRLQSFAVVPLLGLSGSIGAIVGQNWGAHQRDRAKQATLY
AGGFCIVWGLSIAVALFAAGEWFAGFFTDDPAVVDEFARYLTIAAWGYAGYGLLIVGNGILNAVDRAGWALAQSCFRVFA
VMVPFAWLLRGSWGSDAIYGAELAANLVGGAVAMALVWWILNRKPAGQTA
>Mature_449_residues
SENAKLTRGSIPGHLVSQTLPMIIGVAAIMSIGLVDAYFIGQLGSEQLAAISFIFPITVAITSLGVGIMVGINSVVARAL
GEGDDDMAARRANFGIVFAIGCGLVFAISLFVLLDPLFRLMNAEDALLPFIQTYMRPYLMGFPLLLAIMGFNGVLRGQGE
ARKTSYVSLTYAAANWVLDPLLITGAFGFEGFGIAGAAYATVIGWLLGVGMAWWLMRGTPLPVDFGLLRRCSLTEPMKAI
TRVAGPAAFSNAINPIGLSVLTALVAVEGQAAVAGFGAAGRLQSFAVVPLLGLSGSIGAIVGQNWGAHQRDRAKQATLYA
GGFCIVWGLSIAVALFAAGEWFAGFFTDDPAVVDEFARYLTIAAWGYAGYGLLIVGNGILNAVDRAGWALAQSCFRVFAV
MVPFAWLLRGSWGSDAIYGAELAANLVGGAVAMALVWWILNRKPAGQTA

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528
- InterPro:   IPR015522 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47261; Mature: 47130

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSENAKLTRGSIPGHLVSQTLPMIIGVAAIMSIGLVDAYFIGQLGSEQLAAISFIFPITV
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AITSLGVGIMVGINSVVARALGEGDDDMAARRANFGIVFAIGCGLVFAISLFVLLDPLFR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHH
LMNAEDALLPFIQTYMRPYLMGFPLLLAIMGFNGVLRGQGEARKTSYVSLTYAAANWVLD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEHHHHHHHHH
PLLITGAFGFEGFGIAGAAYATVIGWLLGVGMAWWLMRGTPLPVDFGLLRRCSLTEPMKA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHH
ITRVAGPAAFSNAINPIGLSVLTALVAVEGQAAVAGFGAAGRLQSFAVVPLLGLSGSIGA
HHHHCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHH
IVGQNWGAHQRDRAKQATLYAGGFCIVWGLSIAVALFAAGEWFAGFFTDDPAVVDEFARY
HCCCCCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCHHHEECCCCCHHHHHHHHHH
LTIAAWGYAGYGLLIVGNGILNAVDRAGWALAQSCFRVFAVMVPFAWLLRGSWGSDAIYG
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
AELAANLVGGAVAMALVWWILNRKPAGQTA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SENAKLTRGSIPGHLVSQTLPMIIGVAAIMSIGLVDAYFIGQLGSEQLAAISFIFPITV
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
AITSLGVGIMVGINSVVARALGEGDDDMAARRANFGIVFAIGCGLVFAISLFVLLDPLFR
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHH
LMNAEDALLPFIQTYMRPYLMGFPLLLAIMGFNGVLRGQGEARKTSYVSLTYAAANWVLD
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCCCEEEEEEHHHHHHHHH
PLLITGAFGFEGFGIAGAAYATVIGWLLGVGMAWWLMRGTPLPVDFGLLRRCSLTEPMKA
HHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCHHHHH
ITRVAGPAAFSNAINPIGLSVLTALVAVEGQAAVAGFGAAGRLQSFAVVPLLGLSGSIGA
HHHHCCCHHHHHCCCHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHHHHHHHHCCCCCCHH
IVGQNWGAHQRDRAKQATLYAGGFCIVWGLSIAVALFAAGEWFAGFFTDDPAVVDEFARY
HCCCCCCCCHHHHHHHHHEEECCHHHHHHHHHHHHHHHCCHHHEECCCCCHHHHHHHHHH
LTIAAWGYAGYGLLIVGNGILNAVDRAGWALAQSCFRVFAVMVPFAWLLRGSWGSDAIYG
HHHHHHCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
AELAANLVGGAVAMALVWWILNRKPAGQTA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]