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The map label for this gene is cirA [H]

Identifier: 85372892

GI number: 85372892

Start: 89732

End: 91057

Strand: Direct

Name: cirA [H]

Synonym: ELI_00325

Alternate gene names: 85372892

Gene position: 89732-91057 (Clockwise)

Preceding gene: 85372891

Following gene: 85372893

Centisome position: 2.94

GC content: 62.67

Gene sequence:

>1326_bases
ATGAAATATTCGCTTCGCCATTCGATCGCATTCGGCGCACTTGCATCCGCATTGGCCTTTATGCCGAGCGCCGCTTCGGC
GCAGGCCAATCCGCAGCAGGCGGGTGCCGGCGACAGCCAGGTCGAAGACCAGGGCCGCACCATCGTCGTAACCGGCTCGC
TCATTCGTGGCACGCCGGAAGATGCAGCGTTGCCGGTCGATGTCTACACCAGTGAAGATCTGGCGAAGCAGGGCGTCGAC
AGCCCGCTCGAATTTATCAAGGAACTGCCCTCGGTCGGCGCTGTGCTTGGCGATACCAACCAGTTCTCGACTTCCGCGCA
AGGCTTTCAGGGCGTCGGCTCGATCAACCTGCGCGGCCTCGGTCCGCAGCGTACGCTGGTGCTGGTCAACGGCAAGCGCA
CGATCCTTACCCCGGGTGCCGGCTTCGTCGATACGCAGCTGATCCCGCTCTTTGCGCTCGAACGTGTCGAGATCCTGAAG
GACGGCGCAGGCACGACCTACGGTTCCGATGCGATTGCGGGCGTTGCCAACTTCATCACCCGCAGCGATTTCGTCGGGCT
CGAATTGCAGGGCGATTACTCGCTCATCAGCGGTTCGGATAACGATTATTCGCTTAGCGCGCTGGCCGGGTTCGAGTTCG
GCGATGCCAACATAGTCATCGGCGCCGGCTGGCAGCATCGTTCGGAACTGCCGACCACCGAGCGCGACTACACCGCGCTG
CCCTACACTGTGAACCCGTCGGGCTTTTCGGCCCTCTCGACGCCCGGGCTGTTCGCAGCGACCTATCTGACAGGCCAGCC
GGACAACCCCGCTACACCGGGCAACGAGGCGCTCAACACTGTCACTCGCCCGGATCGCGGTTGTAACGAGCTGGGCGGTT
TCCAGGACGGCGCCATCTGTCGCTTCACGTTCATTCCCTTCGACAACATTGTCGAGGACGAGGATCGCTACCAGGTGTTC
GGCCAGTTCACCGTGGACCTCAGCGATCGCGTTCGTTTCCAGGCCGATGCGATGTGGGCACGCAGCGATCTTGAATCGAT
CAACTATTCGCCGGCCTTCCCGCCGACGCAGGGCCCGCGCGGCTCGGGCTTCCTGAGCGCATTTACGACGTCCCCGAATA
ATCCGGGCGTAGCACCGTTTCTCGCGCAGCAAGGGCTTCCGGCGAACAATCCGGGGCCATTGGTAGCCGTTACCAACGTG
CTGTTCCGCCCGCTGGCTATCTCGGCAACCCGCTCGATCCCGATCGCGGTTCGGGCACCGGCTTTGCCAGCAACCAGGCC
TATCGCTTCAGCGGCGGCTTCGACATCGAACTCAATGACAGCCTGA

Upstream 100 bases:

>100_bases
CCTTGCCTTTGCGCATGGGTCGCTGCCTGCGCACCGCGGAAATTGCGTAGAGGCGCCGCTTTCCCGACCGGAAGAGTTTC
AACGGGTTGAGGGAGCCACC

Downstream 100 bases:

>100_bases
CGCTCGATATCGATGGCACGTTCTGGGATTCGGACCGCACGGCTTTCGCGCCGGGCATTGTCGGTACACGCCTGCAGAAT
GCGCTCAACGGCCTCGGCGG

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MKYSLRHSIAFGALASALAFMPSAASAQANPQQAGAGDSQVEDQGRTIVVTGSLIRGTPEDAALPVDVYTSEDLAKQGVD
SPLEFIKELPSVGAVLGDTNQFSTSAQGFQGVGSINLRGLGPQRTLVLVNGKRTILTPGAGFVDTQLIPLFALERVEILK
DGAGTTYGSDAIAGVANFITRSDFVGLELQGDYSLISGSDNDYSLSALAGFEFGDANIVIGAGWQHRSELPTTERDYTAL
PYTVNPSGFSALSTPGLFAATYLTGQPDNPATPGNEALNTVTRPDRGCNELGGFQDGAICRFTFIPFDNIVEDEDRYQVF
GQFTVDLSDRVRFQADAMWARSDLESINYSPAFPPTQGPRGSGFLSAFTTSPNNPGVAPFLAQQGLPANNPGPLVAVTNV
LFRPLAISATRSIPIAVRAPALPATRPIASAAASTSNSMTA

Sequences:

>Translated_441_residues
MKYSLRHSIAFGALASALAFMPSAASAQANPQQAGAGDSQVEDQGRTIVVTGSLIRGTPEDAALPVDVYTSEDLAKQGVD
SPLEFIKELPSVGAVLGDTNQFSTSAQGFQGVGSINLRGLGPQRTLVLVNGKRTILTPGAGFVDTQLIPLFALERVEILK
DGAGTTYGSDAIAGVANFITRSDFVGLELQGDYSLISGSDNDYSLSALAGFEFGDANIVIGAGWQHRSELPTTERDYTAL
PYTVNPSGFSALSTPGLFAATYLTGQPDNPATPGNEALNTVTRPDRGCNELGGFQDGAICRFTFIPFDNIVEDEDRYQVF
GQFTVDLSDRVRFQADAMWARSDLESINYSPAFPPTQGPRGSGFLSAFTTSPNNPGVAPFLAQQGLPANNPGPLVAVTNV
LFRPLAISATRSIPIAVRAPALPATRPIASAAASTSNSMTA
>Mature_441_residues
MKYSLRHSIAFGALASALAFMPSAASAQANPQQAGAGDSQVEDQGRTIVVTGSLIRGTPEDAALPVDVYTSEDLAKQGVD
SPLEFIKELPSVGAVLGDTNQFSTSAQGFQGVGSINLRGLGPQRTLVLVNGKRTILTPGAGFVDTQLIPLFALERVEILK
DGAGTTYGSDAIAGVANFITRSDFVGLELQGDYSLISGSDNDYSLSALAGFEFGDANIVIGAGWQHRSELPTTERDYTAL
PYTVNPSGFSALSTPGLFAATYLTGQPDNPATPGNEALNTVTRPDRGCNELGGFQDGAICRFTFIPFDNIVEDEDRYQVF
GQFTVDLSDRVRFQADAMWARSDLESINYSPAFPPTQGPRGSGFLSAFTTSPNNPGVAPFLAQQGLPANNPGPLVAVTNV
LFRPLAISATRSIPIAVRAPALPATRPIASAAASTSNSMTA

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=155, Percent_Identity=34.1935483870968, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 46265; Mature: 46265

Theoretical pI: Translated: 4.34; Mature: 4.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYSLRHSIAFGALASALAFMPSAASAQANPQQAGAGDSQVEDQGRTIVVTGSLIRGTPE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHHCCCEEEEECCEECCCCC
DAALPVDVYTSEDLAKQGVDSPLEFIKELPSVGAVLGDTNQFSTSAQGFQGVGSINLRGL
CCEEEEEEECCHHHHHHCCCCHHHHHHHCCHHCEEECCCCCCCCCCCCCCCCCCEEEECC
GPQRTLVLVNGKRTILTPGAGFVDTQLIPLFALERVEILKDGAGTTYGSDAIAGVANFIT
CCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
RSDFVGLELQGDYSLISGSDNDYSLSALAGFEFGDANIVIGAGWQHRSELPTTERDYTAL
HCCEEEEEEECCEEEECCCCCCEEEEEEECCEECCCCEEEECCCCCCCCCCCCCCCCEEC
PYTVNPSGFSALSTPGLFAATYLTGQPDNPATPGNEALNTVTRPDRGCNELGGFQDGAIC
CEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCHHHHCCCCCCCEE
RFTFIPFDNIVEDEDRYQVFGQFTVDLSDRVRFQADAMWARSDLESINYSPAFPPTQGPR
EEEECCCCHHCCCCCCEEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCC
GSGFLSAFTTSPNNPGVAPFLAQQGLPANNPGPLVAVTNVLFRPLAISATRSIPIAVRAP
CCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCCEEHHHHHHHCCCEEECCCCCEEEEECC
ALPATRPIASAAASTSNSMTA
CCCCCCCHHHHHHCCCCCCCC
>Mature Secondary Structure
MKYSLRHSIAFGALASALAFMPSAASAQANPQQAGAGDSQVEDQGRTIVVTGSLIRGTPE
CCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCCCHHHCCCEEEEECCEECCCCC
DAALPVDVYTSEDLAKQGVDSPLEFIKELPSVGAVLGDTNQFSTSAQGFQGVGSINLRGL
CCEEEEEEECCHHHHHHCCCCHHHHHHHCCHHCEEECCCCCCCCCCCCCCCCCCEEEECC
GPQRTLVLVNGKRTILTPGAGFVDTQLIPLFALERVEILKDGAGTTYGSDAIAGVANFIT
CCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
RSDFVGLELQGDYSLISGSDNDYSLSALAGFEFGDANIVIGAGWQHRSELPTTERDYTAL
HCCEEEEEEECCEEEECCCCCCEEEEEEECCEECCCCEEEECCCCCCCCCCCCCCCCEEC
PYTVNPSGFSALSTPGLFAATYLTGQPDNPATPGNEALNTVTRPDRGCNELGGFQDGAIC
CEEECCCCCCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHCCCCCCCHHHHCCCCCCCEE
RFTFIPFDNIVEDEDRYQVFGQFTVDLSDRVRFQADAMWARSDLESINYSPAFPPTQGPR
EEEECCCCHHCCCCCCEEEEEEEEEECCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCCCC
GSGFLSAFTTSPNNPGVAPFLAQQGLPANNPGPLVAVTNVLFRPLAISATRSIPIAVRAP
CCCEEEEEECCCCCCCCCHHHHHCCCCCCCCCCEEHHHHHHHCCCEEECCCCCEEEEECC
ALPATRPIASAAASTSNSMTA
CCCCCCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]